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Items: 1 to 20 of 41

1.
ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction
Feiyan Xie, Di Wu, Jing Huang, Xuehe Liu, Yanfang Shen, Jinqing Huang, Zhipeng Su, Jixi Li
Cell Death Dis. 2024 Jul; 15(7): 487. Published online 2024 Jul 9. doi: 10.1038/s41419-024-06889-y
PMCID:
PMC11233663
AbstractArticlePDF–3.3M
2.
The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer
Ailing Wang, Wei-sha Zheng, Zhen Luo, Lian Bai, Shi Zhang
J Transl Med. 2024; 22: 173. Published online 2024 Feb 18. doi: 10.1186/s12967-024-04995-1
PMCID:
PMC10874569
AbstractArticlePDF–5.1M
3.
ZBP1 as a sensor of viral and cellular Z-RNAs: walking the Razor’s Edge
Carly DeAntoneo, Alan Herbert, Siddharth Balachandran
Curr Opin Immunol. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Curr Opin Immunol. 2023 Aug; 83: 102347. Published online 2023 Jun 3. doi: 10.1016/j.coi.2023.102347
PMCID:
PMC10526625
AbstractArticlePDF–1.0M
4.
PANoptosome signaling and therapeutic implications in infection: Central role for ZBP1 to activate inflammasome and PANoptosis
Rajendra Karki, Thirumala-Devi Kanneganti
Curr Opin Immunol. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Curr Opin Immunol. 2023 Aug; 83: 102348. Published online 2023 May 31. doi: 10.1016/j.coi.2023.102348
PMCID:
PMC10524556
AbstractArticlePDF–798K
5.
Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis
Joe Nassour, Lucia Gutierrez Aguiar, Adriana Correia, Tobias T. Schmidt, Laura Mainz, Sara Przetocka, Candy Haggblom, Nimesha Tadepalle, April Williams, Maxim N. Shokhirev, Semih C. Akincilar, Vinay Tergaonkar, Gerald S. Shadel, Jan Karlseder
Nature. 2023; 614(7949): 767–773. Published online 2023 Feb 8. doi: 10.1038/s41586-023-05710-8
PMCID:
PMC9946831
AbstractArticlePDF–7.5M
6.
ZBP1-Mediated Necroptosis: Mechanisms and Therapeutic Implications
Xin-yu Chen, Ying-hong Dai, Xin-xing Wan, Xi-min Hu, Wen-juan Zhao, Xiao-xia Ban, Hao Wan, Kun Huang, Qi Zhang, Kun Xiong
Molecules. 2023 Jan; 28(1): 52. Published online 2022 Dec 21. doi: 10.3390/molecules28010052
PMCID:
PMC9822119
AbstractArticlePDF–1.8M
7.
Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis
Hui Liu, Yuxuan Liu, Wei Fan, Bing Fan
Cell Commun Signal. 2022; 20: 196. Published online 2022 Dec 20. doi: 10.1186/s12964-022-01005-z
PMCID:
PMC9764563
AbstractArticlePDF–6.3M
8.
Oxidative stress induces Z-DNA-binding protein 1–dependent activation of microglia via mtDNA released from retinal pigment epithelial cells
Jamal Saada, Ryan J. McAuley, Michela Marcatti, Tony Zifeng Tang, Massoud Motamedi, Bartosz Szczesny
J Biol Chem. 2022 Jan; 298(1): 101523. Published online 2021 Dec 23. doi: 10.1016/j.jbc.2021.101523
PMCID:
PMC8753185
AbstractArticlePDF–3.3M
9.
Viral Z-RNA triggers ZBP1-dependent cell death
Siddharth Balachandran, Edward S. Mocarski
Curr Opin Virol. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Curr Opin Virol. 2021 Oct 21; 51: 134–140. Published online 2021 Oct 21. doi: 10.1016/j.coviro.2021.10.004
PMCID:
PMC8643332
AbstractArticlePDF–549K
10.
ZBP1: Innate sensor regulating cell death and inflammation
Teneema Kuriakose, Thirumala-Devi Kanneganti
Trends Immunol. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Trends Immunol. 2018 Feb; 39(2): 123–134. Published online 2017 Nov 25. doi: 10.1016/j.it.2017.11.002
PMCID:
PMC5863909
AbstractArticlePDF–1.4M
11.
DNA-dependent Activator of Interferon-regulatory Factors (DAI) Promotes Lupus Nephritis by Activating the Calcium Pathway
Weijuan Zhang, Qian Zhou, Wei Xu, Yanxing Cai, Zhinan Yin, Xiaoming Gao, Sidong Xiong
J Biol Chem. 2013 May 10; 288(19): 13534–13550. Published online 2013 Apr 3. doi: 10.1074/jbc.M113.457218
PMCID:
PMC3650390
AbstractArticlePDF–5.3M
12.
Solution structure of the Zβ domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs
Kyungmin Kim, Bulat I. Khayrutdinov, Chung-Kyung Lee, Hae-Kap Cheong, Sung Wook Kang, Hyejin Park, Sangho Lee, Yang-Gyun Kim, JunGoo Jee, Alexander Rich, Kyeong Kyu Kim, Young Ho Jeon
Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17): 6921–6926. Published online 2011 Apr 6. doi: 10.1073/pnas.1014898107
PMCID:
PMC3084098
AbstractArticlePDF–1.0M
13.
ZBP1 subcellular localization and association with stress granules is controlled by its Z-DNA binding domains
Nikolaus Deigendesch, Friedrich Koch-Nolte, Stefan Rothenburg
Nucleic Acids Res. 2006 Oct; 34(18): 5007–5020. Published online 2006 Sep 20. doi: 10.1093/nar/gkl575
PMCID:
PMC1636418
AbstractArticlePDF–1.4M
14.
ADAR1/ZBP1 in innate immunity, cell death, and disease
Rajendra Karki, Thirumala-Devi Kanneganti
Trends Immunol. Author manuscript; available in PMC 2024 Mar 1.
Published in final edited form as: Trends Immunol. 2023 Mar; 44(3): 201–216. Published online 2023 Jan 27. doi: 10.1016/j.it.2023.01.001
PMCID:
PMC9974732
AbstractArticlePDF–1.1M
15.
Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis
Heather Koehler, Samantha Cotsmire, Ting Zhang, Siddharth Balachandran, Jason W. Upton, Jeffery Langland, Daniel Kalman, Bertram L. Jacobs, Edward S. Mocarski
Cell Host Microbe. Author manuscript; available in PMC 2022 Jul 28.
Published in final edited form as: Cell Host Microbe. 2021 Aug 11; 29(8): 1266–1276.e5. Published online 2021 Jun 29. doi: 10.1016/j.chom.2021.05.009
PMCID:
PMC9333947
AbstractArticlePDF–2.0M
16.
ZBP1 not RIPK1 mediates tumor necroptosis in breast cancer
Jin Young Baik, Zhaoshan Liu, Delong Jiao, Hyung-Joon Kwon, Jiong Yan, Chamila Kadigamuwa, Moran Choe, Ross Lake, Michael Kruhlak, Mayank Tandon, Zhenyu Cai, Swati Choksi, Zheng-gang Liu
Nat Commun. 2021; 12: 2666. Published online 2021 May 11. doi: 10.1038/s41467-021-23004-3
PMCID:
PMC8113527
AbstractArticlePDF–7.3M
17.
DNA Sensing-Independent Inhibition of Herpes Simplex Virus 1 Replication by DAI/ZBP1
Thanh H. Pham, Ki Mun Kwon, Young-Eui Kim, Kyeong Kyu Kim, Jin-Hyun Ahn
J Virol. 2013 Mar; 87(6): 3076–3086. doi: 10.1128/JVI.02860-12
PMCID:
PMC3592125
AbstractArticlePDF–2.5M
18.
Human Cytomegalovirus Induces the Interferon Response via the DNA Sensor ZBP1
Victor R. DeFilippis, David Alvarado, Tina Sali, Stefan Rothenburg, Klaus Früh
J Virol. 2010 Jan; 84(1): 585–598. Published online 2009 Oct 21. doi: 10.1128/JVI.01748-09
PMCID:
PMC2798427
AbstractArticlePDF–2.2M
19.
The crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA reveals an unusual binding mode to Z-DNA
Sung Chul Ha, Doyoun Kim, Hye-Yeon Hwang, Alexander Rich, Yang-Gyun Kim, Kyeong Kyu Kim
Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52): 20671–20676. Published online 2008 Dec 18. doi: 10.1073/pnas.0810463106
PMCID:
PMC2634953
AbstractArticlePDF–1.4M
20.
Complex regulation of the human gene for the Z-DNA binding protein DLM-1
Stefan Rothenburg, Thomas Schwartz, Friedrich Koch-Nolte, Friedrich Haag
Nucleic Acids Res. 2002 Feb 15; 30(4): 993–1000. doi: 10.1093/nar/30.4.993
PMCID:
PMC100341
AbstractArticlePDF–506K

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