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Select item 107816191.

TAF15 amyloid filaments in frontotemporal lobar degeneration

Stephan Tetter, Diana Arseni, Alexey G. Murzin, Yazead Buhidma, Sew Y. Peak-Chew, Holly J. Garringer, Kathy L. Newell, Ruben Vidal, Liana G. Apostolova, Tammaryn Lashley, Bernardino Ghetti, Benjamin Ryskeldi-Falcon

Nature. 2024; 625(7994): 345–351. Published online 2023 Dec 6. doi: 10.1038/s41586-023-06801-2

PMCID:: PMC10781619

Abstract Article PDF–27M

Select item 100860392.

TAF15 promotes cell proliferation, migration and invasion of gastric cancer via activation of the RAF1/MEK/ERK signalling pathway

Li Tang, Chengming Guo, Xu Li, Bo Zhang, Liuye Huang

Sci Rep. 2023; 13: 5846. Published online 2023 Apr 10. doi: 10.1038/s41598-023-31959-0

PMCID:: PMC10086039

Abstract Article PDF–7.6M

Select item 93006783.

The SGYS motif of TAF15 prion-like domain is critical to amyloid fibril formation

Jialin Chen, Xiushuang Yuan, Peng Wei, Daoping Wang, Chen Chen, Quanqiang Guo, Shi-Zhong Luo, Long Chen

Biophys J. 2022 Jul 5; 121(13): 2613–2623. Published online 2022 May 28. doi: 10.1016/j.bpj.2022.05.038

PMCID:: PMC9300678

Abstract Article PDF–2.7M

Select item 79359784.

Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription

Linyu Zuo, Guanwei Zhang, Matthew Massett, Jun Cheng, Zicong Guo, Liang Wang, Yifei Gao, Ru Li, Xu Huang, Pilong Li, Zhi Qi

Nat Commun. 2021; 12: 1491. Published online 2021 Mar 5. doi: 10.1038/s41467-021-21690-7

PMCID:: PMC7935978

Abstract Article PDF–7.1M

Select item 46615365.

Structural delineation of stem-loop RNA binding by human TAF15 protein

Maruthi Kashyap, Akshay Kumar Ganguly, Neel Sarovar Bhavesh

Sci Rep. 2015; 5: 17298. Published online 2015 Nov 27. doi: 10.1038/srep17298

PMCID:: PMC4661536

Abstract Article PDF–1.7M

Select item 29050596.

The TET Family of Proteins: Functions and Roles in Disease

Adelene Y. Tan, James L. Manley

J Mol Cell Biol. 2009 Dec; 1(2): 82–92. Published online 2009 Sep 24. doi: 10.1093/jmcb/mjp025

PMCID:: PMC2905059

Abstract Article PDF–185K

Select item 26808687.

Human U1 snRNA forms a new chromatin-associated snRNP with TAF15

Laure Jobert, Natalia Pinzón, Elodie Van Herreweghe, Beáta E Jády, Apostolia Guialis, Tamás Kiss, László Tora

EMBO Rep. 2009 May; 10(5): 494–500. Published online 2009 Mar 13. doi: 10.1038/embor.2009.24

PMCID:: PMC2680868

Abstract Article PDF–802K

Select item 99996428.

CircDNAJC11 interacts with TAF15 to promote breast cancer progression via enhancing MAPK6 expression and activating the MAPK signaling pathway

Bin Wang, Hang Chen, Yumei Deng, Hong Chen, Lei Xing, Yuping Guo, Min Wang, Junxia Chen

J Transl Med. 2023; 21: 186. Published online 2023 Mar 9. doi: 10.1186/s12967-023-04020-x

PMCID:: PMC9999642

Abstract Article PDF–22M

Select item 59756329.

Lysines in RNA polymerase II C-terminal domain contribute to TAF15 fibril recruitment

Abigail M. Janke, Da Hee Seo, Vahid Rahmanian, Alexander E. Conicella, Kaylee L. Mathews, Kathleen A. Burke, Jeetain Mittal, Nicolas L. Fawzi

Biochemistry. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Biochemistry. 2018 May 1; 57(17): 2549–2563. Published online 2017 Oct 11. doi: 10.1021/acs.biochem.7b00310

PMCID:: PMC5975632

Abstract Article PDF–1.8M

Select item 581876410.

Differential interaction of PRMT1 with RGG‐boxes of the FET family proteins EWS and TAF15

Kim K. C. Li, Bess L. Chau, Kevin A.W. Lee

Protein Sci. 2018 Mar; 27(3): 633–642. Published online 2017 Dec 22. doi: 10.1002/pro.3354

PMCID:: PMC5818764

Abstract Article PDF–1000K

Select item 45224011.

hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.

A Bertolotti, Y Lutz, D J Heard, P Chambon, L Tora

EMBO J. 1996 Sep 16; 15(18): 5022–5031.

PMCID:: PMC452240

Summary Page Browse PDF–2.3M

Select item 1030216712.

m6A-enriched lncRNA LINC00839 promotes tumor progression by enhancing TAF15-mediated transcription of amine oxidase AOC1 in nasopharyngeal carcinoma

Wei-Hong Zheng, Zhi-Qing Long, Zi-Qi Zheng, Lu-Lu Zhang, Ye-Lin Liang, Zhi-Xuan Li, Jia-Wei Lv, Jia Kou, Xiao-Hong Hong, Shi-Wei He, Rui Xu, Guan-Qun Zhou, Na Liu, Jun Ma, Ying Sun, Li Lin, Denghui Wei

J Biol Chem. 2023 Jul; 299(7): 104873. Published online 2023 May 29. doi: 10.1016/j.jbc.2023.104873

PMCID:: PMC10302167

Abstract Article PDF–7.5M

Select item 757181913.

LncRNA PITPNA‐AS1 boosts the proliferation and migration of lung squamous cell carcinoma cells by recruiting TAF15 to stabilize HMGB3 mRNA

Ping Ren, Lei Xing, Xiaodong Hong, Liang Chang, Hong Zhang

Cancer Med. 2020 Oct; 9(20): 7706–7716. Published online 2020 Sep 1. doi: 10.1002/cam4.3268

PMCID:: PMC7571819

Abstract Article PDF–2.2M

Select item 676696914.

NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas

Monica Brenca, Silvia Stacchiotti, Kelly Fassetta, Marta Sbaraglia, Milijana Janjusevic, Dominga Racanelli, Maurizio Polano, Sabrina Rossi, Silvia Brich, Gian P Dagrada, Paola Collini, Chiara Colombo, Alessandro Gronchi, Annalisa Astolfi, Valentina Indio, Maria A Pantaleo, Piero Picci, Paolo G Casali, Angelo P Dei Tos, Silvana Pilotti, Roberta Maestro

J Pathol. 2019 Sep; 249(1): 90–101. Published online 2019 May 14. doi: 10.1002/path.5284

Correction in:: J Pathol. 2021 Aug; 254(5): 606.

PMCID:: PMC6766969

Abstract Article PDF–7.4M

Select item 510035115.

Role of FET proteins in neurodegenerative disorders

Francesca Svetoni, Paola Frisone, Maria Paola Paronetto

RNA Biol. 2016; 13(11): 1089–1102. Published online 2016 Jul 14. doi: 10.1080/15476286.2016.1211225

PMCID:: PMC5100351

Abstract Article PDF–797K

Select item 345798016.

Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions

Jenny Blechingberg, Yonglun Luo, Lars Bolund, Christian Kroun Damgaard, Anders Lade Nielsen

PLoS One. 2012; 7(9): e46251. Published online 2012 Sep 25. doi: 10.1371/journal.pone.0046251

PMCID:: PMC3457980

Abstract Article PDF–1.1M

Select item 337323817.

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis

Julien Couthouis, Michael P. Hart, Renske Erion, Oliver D. King, Zamia Diaz, Tadashi Nakaya, Fadia Ibrahim, Hyung-Jun Kim, Jelena Mojsilovic-Petrovic, Saarene Panossian, Cecilia E. Kim, Edward C. Frackelton, Jennifer A. Solski, Kelly L. Williams, Dana Clay-Falcone, Lauren Elman, Leo McCluskey, Robert Greene, Hakon Hakonarson, Robert G. Kalb, Virginia M.Y. Lee, John Q. Trojanowski, Garth A. Nicholson, Ian P. Blair, Nancy M. Bonini, Vivianna M. Van Deerlin, Zissimos Mourelatos, James Shorter, Aaron D. Gitler

Hum Mol Genet. 2012 Jul 1; 21(13): 2899–2911. Published online 2012 Mar 27. doi: 10.1093/hmg/dds116

PMCID:: PMC3373238

Abstract Article PDF–520K

Select item 324851818.

A yeast functional screen predicts new candidate ALS disease genes

Julien Couthouis, Michael P. Hart, James Shorter, Mariely DeJesus-Hernandez, Renske Erion, Rachel Oristano, Annie X. Liu, Daniel Ramos, Niti Jethava, Divya Hosangadi, James Epstein, Ashley Chiang, Zamia Diaz, Tadashi Nakaya, Fadia Ibrahim, Hyung-Jun Kim, Jennifer A. Solski, Kelly L. Williams, Jelena Mojsilovic-Petrovic, Caroline Ingre, Kevin Boylan, Neill R. Graff-Radford, Dennis W. Dickson, Dana Clay-Falcone, Lauren Elman, Leo McCluskey, Robert Greene, Robert G. Kalb, Virginia M.-Y. Lee, John Q. Trojanowski, Albert Ludolph, Wim Robberecht, Peter M. Andersen, Garth A. Nicholson, Ian P. Blair, Oliver D. King, Nancy M. Bonini, Vivianna Van Deerlin, Rosa Rademakers, Zissimos Mourelatos, Aaron D. Gitler

Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52): 20881–20890. Published online 2011 Nov 7. doi: 10.1073/pnas.1109434108

Correction in:: Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2220845120.

PMCID:: PMC3248518

Abstract Article PDF–1.9M

Select item 317053919.

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations

Manuela Neumann, Eva Bentmann, Dorothee Dormann, Ali Jawaid, Mariely DeJesus-Hernandez, Olaf Ansorge, Sigrun Roeber, Hans A. Kretzschmar, David G. Munoz, Hirofumi Kusaka, Osamu Yokota, Lee-Cyn Ang, Juan Bilbao, Rosa Rademakers, Christian Haass, Ian R. A. Mackenzie

Brain. 2011 Sep; 134(9): 2595–2609. Published online 2011 Aug 19. doi: 10.1093/brain/awr201

PMCID:: PMC3170539

Abstract Article PDF–1.8M

Select item 305653820.

mRNA and Protein Levels of FUS, EWSR1 and TAF15 are Upregulated in Liposarcoma

Jessica I. Spitzer, Stacy Ugras, Simon Runge, Penelope Decarolis, Christina Antonescu, Tom Tuschl, Samuel Singer

Genes Chromosomes Cancer. Author manuscript; available in PMC 2012 May 1.

Published in final edited form as: Genes Chromosomes Cancer. 2011 May; 50(5): 338–347. Published online 2011 Feb 22. doi: 10.1002/gcc.20858

PMCID:: PMC3056538

Abstract Article PDF–104K

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