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Select item 88874721.

Nuclear export restricts Gdown1 to a mitotic function

Christopher B Ball, Mrutyunjaya Parida, Juan F Santana, Benjamin M Spector, Gustavo A Suarez, David H Price

Nucleic Acids Res. 2022 Feb 28; 50(4): 1908–1926. Published online 2022 Jan 20. doi: 10.1093/nar/gkac015

PMCID:: PMC8887472

Abstract Article PDF–6.8M

Select item 50553132.

Gdown1 Associates Efficiently with RNA Polymerase II after Promoter Clearance and Displaces TFIIF during Transcript Elongation

Elizabeth DeLaney, Donal S. Luse

PLoS One. 2016; 11(10): e0163649. Published online 2016 Oct 7. doi: 10.1371/journal.pone.0163649

PMCID:: PMC5055313

Abstract Article PDF–2.0M

Select item 40362533.

Functional Interactions of the RNA Polymerase II-interacting Proteins Gdown1 and TFIIF

Melissa A. Mullen Davis, Jiannan Guo, David H. Price, Donal S. Luse

J Biol Chem. 2014 Apr 18; 289(16): 11143–11152. Published online 2014 Mar 4. doi: 10.1074/jbc.M113.544395

PMCID:: PMC4036253

Abstract Article PDF–2.1M

Select item 40074554.

Regulation of RNA Polymerase II Termination by Phosphorylation of Gdown1

Jiannan Guo, Michael E. Turek, David H. Price

J Biol Chem. 2014 May 2; 289(18): 12657–12665. Published online 2014 Mar 14. doi: 10.1074/jbc.M113.537662

PMCID:: PMC4007455

Abstract Article PDF–1.7M

Select item 34338575.

Regulation of mammalian transcription by Gdown1 through a novel steric crosstalk revealed by cryo-EM

Yi-Min Wu, Jen-Wei Chang, Chun-Hsiung Wang, Yen-Chen Lin, Pei-lun Wu, Shih-hsin Huang, Chia-Chi Chang, Xiaopeng Hu, Averell Gnatt, Wei-hau Chang

EMBO J. 2012 Aug 29; 31(17): 3575–3587. Published online 2012 Jul 31. doi: 10.1038/emboj.2012.205

PMCID:: PMC3433857

Abstract Article PDF–1.7M

Select item 32595266.

Functional association of Gdown1 with RNA polymerase II poised on human genes

Bo Cheng, Tiandao Li, Peter B. Rahl, Todd E. Adamson, Nicholas B. Loudas, Jiannan Guo, Katayoun Varzavand, Jeffrey J. Cooper, Xiaopeng Hu, Averell Gnatt, Richard A. Young, David H. Price

Mol Cell. Author manuscript; available in PMC 2013 Jan 13.

Published in final edited form as: Mol Cell. 2012 Jan 13; 45(1): 38–50. doi: 10.1016/j.molcel.2011.10.022

PMCID:: PMC3259526

Abstract Article PDF–1.0M

Select item 32595317.

Transcriptional regulation by Pol II(G) involving Mediator and competitive interactions of Gdown1 and TFIIF with Pol II

Miki Jishage, Sohail Malik, Ulrich Wagner, Beatrix Uberheide, Yasushi Ishihama, Xiaopeng Hu, Brian T. Chait, Averell Gnatt, Bing Ren, Robert G. Roeder

Mol Cell. Author manuscript; available in PMC 2013 Jan 13.

Published in final edited form as: Mol Cell. 2012 Jan 13; 45(1): 51–63. doi: 10.1016/j.molcel.2011.12.014

Correction in:: volume 47 on page 491

PMCID:: PMC3259531

Abstract Article PDF–3.4M

Select item 14804378.

A Mediator-responsive form of metazoan RNA polymerase II

Xiaopeng Hu, Sohail Malik, Costin Catalin Negroiu, Kyle Hubbard, Chidambaram Natesa Velalar, Brian Hampton, Dan Grosu, Jennifer Catalano, Robert G. Roeder, Averell Gnatt

Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25): 9506–9511. Published online 2006 Jun 12. doi: 10.1073/pnas.0603702103

PMCID:: PMC1480437

Abstract Article PDF–611K

Select item 62984269.

Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1

Miki Jishage, Xiaodi Yu, Yi Shi, Sai J. Ganesan, Wei-Yi Chen, Andrej Sali, Brian T. Chait, Francisco J. Asturias, Robert G. Roeder

Nat Struct Mol Biol. Author manuscript; available in PMC 2019 Mar 6.

Published in final edited form as: Nat Struct Mol Biol. 2018 Sep; 25(9): 859–867. Published online 2018 Sep 6. doi: 10.1038/s41594-018-0118-5

PMCID:: PMC6298426

Abstract Article PDF–2.1M

Select item 888541810.

The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis

Christiaan J. Stavast, Iris van Zuijen, Elena Karkoulia, Arman Özçelik, Antoinette van Hoven-Beijen, Leticia G. Leon, Jane S. A. Voerman, George M. C. Janssen, Peter A. van Veelen, Monika Burocziova, Rutger W. W. Brouwer, Wilfred F. J. van IJcken, Alex Maas, Eric M. Bindels, Vincent H. J. van der Velden, Christopher Schliehe, Peter D. Katsikis, Meritxell Alberich-Jorda, Stefan J. Erkeland

Leukemia. 2022; 36(3): 687–700. Published online 2021 Nov 5. doi: 10.1038/s41375-021-01461-5

PMCID:: PMC8885418

Abstract Article PDF–5.0M

Select item 326578211.

Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B

Zuyao Ni, Jonathan B Olsen, Xinghua Guo, Guoqing Zhong, Eric Dongliang Ruan, Edyta Marcon, Peter Young, Hongbo Guo, Joyce Li, Jason Moffat, Andrew Emili, Jack F Greenblatt

Transcription. 2011 Sep-Oct; 2(5): 237–242. Published online 2011 Sep 1. doi: 10.4161/trns.2.5.17803

PMCID:: PMC3265782

Abstract Article PDF–1.7M

Select item 359192112.

Identification of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Replication by In Silico Screening Targeting Cyclin T1/Tat Interaction

Takayuki Hamasaki, Mika Okamoto, Masanori Baba

Antimicrob Agents Chemother. 2013 Mar; 57(3): 1323–1331. doi: 10.1128/AAC.01711-12

PMCID:: PMC3591921

Abstract Article PDF–2.2M

Select item 323445013.

HIV Latency

Robert F. Siliciano, Warner C. Greene

Cold Spring Harb Perspect Med. 2011 Sep; 1(1): a007096. doi: 10.1101/cshperspect.a007096

PMCID:: PMC3234450

Abstract Article PDF–1.0M

Select item 188768914.

The HIV-1 Virion-associated Protein Vpr Is a Coactivator of the Human Glucocorticoid Receptor

Tomoshige Kino, Alexander Gragerov, Jeffrey B. Kopp, Roland H. Stauber, George N. Pavlakis, George P. Chrousos

J Exp Med. 1999 Jan 4; 189(1): 51–62. doi: 10.1084/jem.189.1.51

PMCID:: PMC1887689

Abstract Article PDF–283K

Select item 15066815.

Human Immunodeficiency Virus Type 1 (HIV-1) Vpr Enhances Expression from Unintegrated HIV-1 DNA

Betty Poon, Irvin S. Y. Chen

J Virol. 2003 Apr; 77(7): 3962–3972. doi: 10.1128/JVI.77.7.3962-3972.2003

PMCID:: PMC150668

Abstract Article PDF–620K

Select item 347539516.

HIV-1 Reverse Transcription

Wei-Shau Hu, Stephen H. Hughes

Cold Spring Harb Perspect Med. 2012 Oct; 2(10): a006882. doi: 10.1101/cshperspect.a006882

PMCID:: PMC3475395

Abstract Article PDF–1.0M

Select item 359239417.

The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation

Zichong Li, Jia Guo, Yuntao Wu, Qiang Zhou

Nucleic Acids Res. 2013 Jan; 41(1): 277–287. Published online 2012 Oct 18. doi: 10.1093/nar/gks976

PMCID:: PMC3592394

Abstract Article PDF–2.5M

Select item 250483518.

A quantitative atlas of mitotic phosphorylation

Noah Dephoure, Chunshui Zhou, Judit Villén, Sean A. Beausoleil, Corey E. Bakalarski, Stephen J. Elledge, Steven P. Gygi

Proc Natl Acad Sci U S A. 2008 Aug 5; 105(31): 10762–10767. Published online 2008 Jul 31. doi: 10.1073/pnas.0805139105

PMCID:: PMC2504835

Abstract Article PDF–1.0M

Select item 333563219.

The Role of RNA Polymerase II Elongation Control in HIV-1 Gene Expression, Replication, and Latency

Kyle A. Nilson, David H. Price

Genet Res Int. 2011; 2011: 726901. Published online 2011 Oct 13. doi: 10.4061/2011/726901

PMCID:: PMC3335632

Abstract Article PDF–1.3M

Select item 375551920.

Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic development

Satinder Dahiya, Michael R. Nonnemacher, Brian Wigdahl

J Gen Virol. 2012 Jun; 93(Pt 6): 1151–1172. doi: 10.1099/vir.0.041186-0

PMCID:: PMC3755519

Abstract Article PDF–931K

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PMC Links for Gene (Select 81488) (44)
PMC
RecName: Full=DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5; AltN...
RecName: Full=DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5; AltName: Full=DNA-directed RNA polymerase II subunit M, isoforms 4/5
gi|74709235|sp|Q6EEV4.1|GL1AD_HUMAN

Protein
RecName: Full=26S proteasome non-ATPase regulatory subunit 4; AltName: Full=26S ...
RecName: Full=26S proteasome non-ATPase regulatory subunit 4; AltName: Full=26S proteasome regulatory subunit RPN10; AltName: Full=26S proteasome regulatory subunit S5A; AltName: Full=Antisecretory factor 1; Short=AF; Short=ASF; AltName: Full=Multiubiquitin chain-binding protein
gi|1709796|sp|P55036.1|PSMD4_HUMAN

Protein

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