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Items: 1 to 20 of 89

1.
SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling
Chong Zeng, Jie Lin, Ketao Zhang, Huohui Ou, Ke Shen, Qingbo Liu, Zibo Wei, Xinhuai Dong, Xiaokang Zeng, Liming Zeng, Weidong Wang, Jie Yao
Cancer Sci. 2022 Nov; 113(11): 3766–3775. Published online 2022 Sep 8. doi: 10.1111/cas.15531
PMCID:
PMC9633309
AbstractArticlePDF–17M
2.
A functional variant of SHARPIN confers increased risk of late-onset Alzheimer’s disease
Yuya Asanomi, Daichi Shigemizu, Shintaro Akiyama, Akinori Miyashita, Risa Mitsumori, Norikazu Hara, Takeshi Ikeuchi, Shumpei Niida, Kouichi Ozaki
J Hum Genet. 2022; 67(4): 203–208. Published online 2021 Nov 5. doi: 10.1038/s10038-021-00987-x
PMCID:
PMC8948087
AbstractArticlePDF–878K
3.
Imaging genomics discovery of a new risk variant for Alzheimer's disease in the postsynaptic SHARPIN gene
Sourena Soheili‐Nezhad, Neda Jahanshad, Sebastian Guelfi, Reza Khosrowabadi, Andrew J. Saykin, Paul M. Thompson, Christian F. Beckmann, Emma Sprooten, Mojtaba Zarei, the Alzheimer's Disease Neuroimaging
Hum Brain Mapp. 2020 Sep; 41(13): 3737–3748. Published online 2020 Jun 18. doi: 10.1002/hbm.25083
PMCID:
PMC7416020
AbstractArticlePDF–9.3M
4.
A novel gammaretroviral shuttle vector insertional mutagenesis screen identifies SHARPIN as a breast cancer metastasis gene and prognostic biomarker
Victor M. Bii, Dustin T. Rae, Grant D. Trobridge
Oncotarget. 2015 Nov 24; 6(37): 39507–39520. Published online 2015 Oct 25. doi: 10.18632/oncotarget.6232
PMCID:
PMC4741842
AbstractArticlePDF–2.5M
5.
Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk
Jason De Melo, Damu Tang
PLoS One. 2015; 10(5): e0127546. Published online 2015 May 19. doi: 10.1371/journal.pone.0127546
PMCID:
PMC4438068
AbstractArticlePDF–6.4M
6.
Crystallization of SHARPIN using an automated two-dimensional grid screen for optimization
Benjamin Stieglitz, Katrin Rittinger, Lesley F. Haire
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1; 68(Pt 7): 816–819. Published online 2012 Jun 28. doi: 10.1107/S1744309112022208
PMCID:
PMC3388930
AbstractArticlePDF–489K
7.
Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold
Benjamin Stieglitz, Lesley F. Haire, Ivan Dikic, Katrin Rittinger
J Biol Chem. 2012 Jun 15; 287(25): 20823–20829. Published online 2012 May 1. doi: 10.1074/jbc.M112.359547
PMCID:
PMC3375506
AbstractArticlePDF–1.8M
8.
A missense variant in SHARPIN mediates Alzheimer’s disease-specific brain damages
Jun Young Park, Dongsoo Lee, Jang Jae Lee, Jungsoo Gim, Tamil Iniyan Gunasekaran, Kyu Yeong Choi, Sarang Kang, Ah Ra Do, Jinyeon Jo, Juhong Park, Kyungtaek Park, Donghe Li, Sanghun Lee, Hoowon Kim, Immanuel Dhanasingh, Suparna Ghosh, Seula Keum, Jee Hye Choi, Gyun Jee Song, Lee Sael, Sangmyung Rhee, Simon Lovestone, Eunae Kim, Seung Hwan Moon, Byeong C. Kim, SangYun Kim, Andrew J. Saykin, Kwangsik Nho, Sung Haeng Lee, Lindsay A. Farrer, Gyungah R. Jun, Sungho Won, Kun Ho Lee, for the Alzheimer’s Disease Neuroimaging Initiative
Transl Psychiatry. 2021; 11: 590. Published online 2021 Nov 16. doi: 10.1038/s41398-021-01680-5
PMCID:
PMC8595886
AbstractArticlePDF–1.8M
9.
SHARPIN regulates the development of clear cell renal cell carcinoma by promoting von Hippel‐Lindau protein ubiquitination and degradation
Rusha Yin, Shuai Liu
Cancer Sci. 2021 Oct; 112(10): 4100–4111. Published online 2021 Aug 22. doi: 10.1111/cas.15096
PMCID:
PMC8486188
AbstractArticlePDF–1.8M
10.
SHARPIN Inhibits Esophageal Squamous Cell Carcinoma Progression by Modulating Hippo Signaling
Aijia Zhang, Weilong Wang, Zhijun Chen, Dan Pang, Xiaofeng Zhou, Kui Lu, Jinghan Hou, Sujie Wang, Can Gao, Benjie Lv, Ziyi Yan, Zhen Chen, Jian Zhu, Lidong Wang, Ting Zhuang, Xiumin Li
Neoplasia. 2020 Feb; 22(2): 76–85. Published online 2019 Dec 26. doi: 10.1016/j.neo.2019.12.001
PMCID:
PMC6939053
AbstractArticlePDF–2.0M
11.
SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation
Ting Zhuang, Sifan Yu, Lichen Zhang, Huijie Yang, Xin Li, Yingxiang Hou, Zhenhua Liu, Yuanyuan Shi, Weilong Wang, Na Yu, Anqi Li, Xuefeng Li, Xiumin Li, Gang Niu, Juntao Xu, Muhammad Sharif Hasni, Kun Mu, Hui Wang, Jian Zhu
Oncotarget. 2017 Sep 29; 8(44): 77137–77151. Published online 2017 Aug 19. doi: 10.18632/oncotarget.20368
PMCID:
PMC5652769
AbstractArticlePDF–13M
12.
Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells
Lizhi He, Alistair Ingram, Adrian P. Rybak, Damu Tang
J Clin Invest. 2010 Jun 1; 120(6): 2094–2108. Published online 2010 May 10. doi: 10.1172/JCI40778
PMCID:
PMC2877943
AbstractArticlePDF–4.4M
13.
Identification and molecular analysis of RNF31 Q622H germline polymorphism
Seshiru Nakazawa, Ryo Mamiya, Reika Kawabata-Iwakawa, Daisuke Oikawa, Kyoichi Kaira, Fuminori Tokunaga, Sumihito Nobusawa, Yusuke Sato, Atsushi Sasaki, Toshiki Yajima, Ken Shirabe
Oncol Lett. 2022 Nov; 24(5): 394. Published online 2022 Sep 21. doi: 10.3892/ol.2022.13514
PMCID:
PMC9533369
AbstractArticlePDF–3.1M
14.
Serine 165 phosphorylation of SHARPIN regulates the activation of NF-κB
An Thys, Kilian Trillet, Sara Rosińska, Audrey Gayraud, Tiphaine Douanne, Yannic Danger, Clotilde C.N. Renaud, Luc Antigny, Régis Lavigne, Charles Pineau, Emmanuelle Com, Franck Vérité, Julie Gavard, Nicolas Bidère
iScience. 2021 Jan 22; 24(1): 101939. Published online 2020 Dec 13. doi: 10.1016/j.isci.2020.101939
PMCID:
PMC7773595
AbstractArticlePDF–14M
15.
Linear Ubiquitin Code: Its Writer, Erasers, Decoders, Inhibitors, and Implications in Disorders
Daisuke Oikawa, Yusuke Sato, Hidefumi Ito, Fuminori Tokunaga
Int J Mol Sci. 2020 May; 21(9): 3381. Published online 2020 May 11. doi: 10.3390/ijms21093381
PMCID:
PMC7246992
AbstractArticlePDF–3.2M
16.
SHARPIN regulates cell proliferation of cutaneous basal cell carcinoma via inactivation of the transcriptional factors GLI2 and c-JUN
Yao Yang, Yan-Hua Liang, Yan Zheng, Ling-Jie Tang, Si-Tong Zhou, Jing-Na Zhu
Mol Med Rep. 2020 Apr; 21(4): 1799–1808. Published online 2020 Feb 7. doi: 10.3892/mmr.2020.10981
PMCID:
PMC7057814
AbstractArticlePDF–1.0M
17.
LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB
Jessica Noad, Alexander von der Malsburg, Claudio Pathe, Martin A. Michel, David Komander, Felix Randow
Nat Microbiol. Author manuscript; available in PMC 2017 Nov 8.
Published in final edited form as: Nat Microbiol. 2017 May 8; 2: 17063. Published online 2017 May 8. doi: 10.1038/nmicrobiol.2017.63
PMCID:
PMC5576533
AbstractArticlePDF–2.0M
18.
SHARPIN Facilitates p53 Degradation in Breast Cancer Cells
Huijie Yang, Sifan Yu, Weilong Wang, Xin Li, Yingxiang Hou, Zhenhua Liu, Yuanyuan Shi, Kun Mu, Gang Niu, Juntao Xu, Hui Wang, Jian Zhu, Ting Zhuang
Neoplasia. 2017 Feb; 19(2): 84–92. Published online 2017 Jan 5. doi: 10.1016/j.neo.2016.12.002
PMCID:
PMC5219588
AbstractArticlePDF–1.1M
19.
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
Benjamin Stieglitz, Rohini R. Rana, Marios G. Koliopoulos, Aylin C. Morris-Davies, Veronique Schaeffer, Evangelos Christodoulou, Steven Howell, Nicholas R. Brown, Ivan Dikic, Katrin Rittinger
Nature. Author manuscript; available in PMC 2014 May 21.
Published in final edited form as: Nature. 2013 Nov 21; 503(7476): 422–426. Published online 2013 Oct 20. doi: 10.1038/nature12638
PMCID:
PMC3838313
AbstractArticlePDF–2.1M
20.
HOIP modulates the stability of GPx4 by linear ubiquitination
Kangyun Dong, Ran Wei, Taijie Jin, Mengmeng Zhang, Jiali Shen, Huaijiang Xiang, Bing Shan, Junying Yuan, Ying Li
Proc Natl Acad Sci U S A. 2022 Nov 1; 119(44): e2214227119. Published online 2022 Oct 24. doi: 10.1073/pnas.2214227119
PMCID:
PMC9636971
AbstractArticlePDF–2.3M

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