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Items: 1 to 20 of 30

1.
AP4 suppresses DNA damage, chromosomal instability and senescence via inducing MDC1/Mediator of DNA damage Checkpoint 1 and repressing MIR22HG/miR-22-3p
Jinjiang Chou, Markus Kaller, Stephanie Jaeckel, Matjaz Rokavec, Heiko Hermeking
Mol Cancer. 2022; 21: 120. Published online 2022 May 27. doi: 10.1186/s12943-022-01581-1
PMCID:
PMC9137087
AbstractArticlePDF–13M
2.
Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis
Margaret A. Potts, Shinsuke Mizutani, Alexandra L. Garnham, Connie S. N. Li Wai Suen, Andrew J. Kueh, Lin Tai, Martin Pal, Andreas Strasser, Marco J. Herold
Cell Death Differ. 2023 Jun; 30(6): 1447–1456. Published online 2023 Mar 9. doi: 10.1038/s41418-023-01145-w
PMCID:
PMC10244435
AbstractArticlePDF–3.2M
3.
AP4 is required for mitogen- and c-MYC-induced cell cycle progression
Rene Jackstadt, Heiko Hermeking
Oncotarget. 2014 Sep; 5(17): 7316–7327. Published online 2014 Aug 19. doi: 10.18632/oncotarget.2348
PMCID:
PMC4202125
AbstractArticlePDF–4.3M
4.
c-Myc-induced transcription factor AP4 is required for CD8+ T cell-mediated host protection
Chun Chou, Amelia K. Pinto, Jonathan D. Curtis, Stephen P. Persaud, Marina Cella, Chih-Chung Lin, Brian T. Edelson, Paul M. Allen, Marco Colonna, Erika L. Pearce, Michael S. Diamond, Takeshi Egawa
Nat Immunol. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: Nat Immunol. 2014 Sep; 15(9): 884–893. Published online 2014 Jul 13. doi: 10.1038/ni.2943
PMCID:
PMC4139462
AbstractArticlePDF–1.6M
5.
Transcription factor AP-4 is a ligand for immunoglobulin-kappa promoter E-box elements.
A Aranburu, R Carlsson, C Persson, T Leanderson
Biochem J. 2001 Mar 1; 354(Pt 2): 431–438. doi: 10.1042/0264-6021:3540431
PMCID:
PMC1221672
SummaryPDF–248K
6.
Unexpected suppression of tumorigenesis by c-MYC via TFAP4-dependent restriction of stemness in B lymphocytes
Elena Tonc, Yoshiko Takeuchi, Chun Chou, Yu Xia, Melanie Holmgren, Chika Fujii, Saravanan Raju, Gue Su Chang, Masahiro Iwamoto, Takeshi Egawa
Blood. 2021 Dec 16; 138(24): 2526–2538. doi: 10.1182/blood.2021011711
PMCID:
PMC8678995
AbstractArticle
7.
Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells
Stephanie Jaeckel, Markus Kaller, Rene Jackstadt, Ursula Götz, Susanna Müller, Sophie Boos, David Horst, Peter Jung, Heiko Hermeking
Nat Commun. 2018; 9: 3573. Published online 2018 Sep 3. doi: 10.1038/s41467-018-06001-x
PMCID:
PMC6120921
AbstractArticlePDF–3.7M
8.
Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene
Takeshi Egawa, Dan R. Littman
Proc Natl Acad Sci U S A. 2011 Sep 6; 108(36): 14873–14878. Published online 2011 Aug 22. doi: 10.1073/pnas.1112293108
PMCID:
PMC3169121
AbstractArticlePDF–782K
9.
AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation
R Jackstadt, P Jung, H Hermeking
Cell Death Dis. 2013 Aug; 4(8): e775. Published online 2013 Aug 15. doi: 10.1038/cddis.2013.282
PMCID:
PMC3763444
AbstractArticlePDF–1.2M
10.
The transcription factor AP4 mediates resolution of chronic viral infection through amplification of germinal center B cell responses
Chun Chou, Daniel J. Verbaro, Elena Tonc, Melanie Holmgren, Marina Cella, Marco Colonna, Deepta Bhattacharya, Takeshi Egawa
Immunity. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Immunity. 2016 Sep 20; 45(3): 570–582. Published online 2016 Aug 23. doi: 10.1016/j.immuni.2016.07.023
PMCID:
PMC5037962
AbstractArticlePDF–3.2M
11.
A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells
Mi-Young Kim, Byung Chul Jeong, Ji Hee Lee, Hae Jin Kee, Hyun Kook, Nack Sung Kim, Yoon Ha Kim, Jong-Keun Kim, Kyu Youn Ahn, Kyung Keun Kim
Proc Natl Acad Sci U S A. 2006 Aug 29; 103(35): 13074–13079. Published online 2006 Aug 21. doi: 10.1073/pnas.0601915103
PMCID:
PMC1551900
AbstractArticlePDF–1.6M
12.
The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein
Loan K. Phan, Feng Lin, Charles A. LeDuc, Wendy K. Chung, Rudolph L. Leibel
J Clin Invest. 2002 Nov 15; 110(10): 1449–1459. doi: 10.1172/JCI16131
PMCID:
PMC151815
AbstractArticlePDF–2.6M
13.
Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain
Elizabeth AD Hammock, Kathie L Eagleson, Susan Barlow, Laurie R Earls, David M Miller, III, Pat Levitt
Neural Dev. 2010; 5: 32. Published online 2010 Dec 1. doi: 10.1186/1749-8104-5-32
PMCID:
PMC3006369
AbstractArticlePDF–792K
14.
Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation
Jeffrey D. Stevens, Eric H. Roalson, Michael K. Skinner
Differentiation. Author manuscript; available in PMC 2017 Dec 13.
Published in final edited form as: Differentiation. 2008 Nov; 76(9): 1006–1022. Published online 2008 Jun 4. doi: 10.1111/j.1432-0436.2008.00285.x
PMCID:
PMC5728086
AbstractArticlePDF–2.4M
15.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
16.
A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract
Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith
Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130
PMCID:
PMC3439845
AbstractArticlePDF–1.4M
17.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M
18.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
19.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
20.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome
Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz
Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100
PMCID:
PMC187885
AbstractArticlePDF–287K

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