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Select item 70601761.

Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes

Yi Ching Esther Wan, Tsz Chui Sophia Leung, Dongbo Ding, Xulun Sun, Jiaxian Liu, Lina Zhu, Tze Zhen Evangeline Kang, Du Yang, Yuchen Zhang, Jitian Zhang, Chengmin Qian, Michael Shing Yan Huen, Qing Li, Maggie Zi Ying Chow, Zongli Zheng, Junhong Han, Ajay Goel, Xin Wang, Toyotaka Ishibashi, Kui Ming Chan

Signal Transduct Target Ther. 2020; 5: 27. Published online 2020 Mar 6. doi: 10.1038/s41392-020-0131-0

PMCID:: PMC7060176

Article PDF–1.4M

Select item 41993672.

Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate

Gilad Fuchs, Dror Hollander, Yoav Voichek, Gil Ast, Moshe Oren

Genome Res. 2014 Oct; 24(10): 1572–1583. doi: 10.1101/gr.176487.114

PMCID:: PMC4199367

Abstract Article PDF–1.9M

Select item 33717063.

H2B monoubiquitylation is a 5′-enriched active transcription mark and correlates with exon–intron structure in human cells

Inkyung Jung, Seung-Kyoon Kim, Mirang Kim, Yong-Mahn Han, Yong Sung Kim, Dongsup Kim, Daeyoup Lee

Genome Res. 2012 Jun; 22(6): 1026–1035. doi: 10.1101/gr.120634.111

PMCID:: PMC3371706

Abstract Article PDF–1.7M

Select item 33539454.

Coupling of Glucose Deprivation with Impaired Histone H2B Monoubiquitination in Tumors

Yasuyo Urasaki, Linda Heath, C. Wilson Xu

PLoS One. 2012; 7(5): e36775. Published online 2012 May 16. doi: 10.1371/journal.pone.0036775

PMCID:: PMC3353945

Abstract Article PDF–1.6M

Select item 73269725.

The H2BG53D oncohistone directly upregulates ANXA3 transcription and enhances cell migration in pancreatic ductal adenocarcinoma

Yi Ching Esther Wan, Jiaxian Liu, Lina Zhu, Tze Zhen Evangeline Kang, Xiaoxuan Zhu, John Lis, Toyotaka Ishibashi, Charles G. Danko, Xin Wang, Kui Ming Chan

Signal Transduct Target Ther. 2020; 5: 106. Published online 2020 Jun 30. doi: 10.1038/s41392-020-00219-2

PMCID:: PMC7326972

Article PDF–1.1M

Select item 47626306.

Top-down and Middle-down Protein Analysis Reveals that Intact and Clipped Human Histones Differ in Post-translational Modification Patterns

Andrey Tvardovskiy, Krzysztof Wrzesinski, Simone Sidoli, Stephen J. Fey, Adelina Rogowska-Wrzesinska, Ole N. Jensen

Mol Cell Proteomics. 2015 Dec; 14(12): 3142–3153. Published online 2015 Sep 30. doi: 10.1074/mcp.M115.048975

PMCID:: PMC4762630

Abstract Article PDF–1.9M

Select item 47458807.

Expressing Status and Correlation of ARID1A and Histone H2B on Breast Cancer

Yan Wu, Yan Gu, Shanyu Guo, Qiancheng Dai, Wei Zhang

Biomed Res Int. 2016; 2016: 7593787. Published online 2016 Jan 21. doi: 10.1155/2016/7593787

PMCID:: PMC4745880

Abstract Article PDF–2.8M

Select item 47444068.

Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer

Marsela Braunstein, Linda Liao, Nicola Lyttle, Nazleen Lobo, Karen J. Taylor, Paul M. Krzyzanowski, Irina Kalatskaya, Cindy Q. Yao, Lincoln D. Stein, Paul C. Boutros, Christopher J. Twelves, Richard Marcellus, John M. S. Bartlett, Melanie Spears

Breast Cancer Res. 2016; 18: 16. Published online 2016 Feb 6. doi: 10.1186/s13058-016-0676-6

PMCID:: PMC4744406

Abstract Article PDF–1.8M

Select item 45473109.

Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin

Matthew T. Holt, Yael David, Sam Pollock, Zhanyun Tang, Jongcheol Jeon, Jaehoon Kim, Robert G. Roeder, Tom W. Muir

Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33): 10365–10370. Published online 2015 Aug 3. doi: 10.1073/pnas.1504483112

PMCID:: PMC4547310

Abstract Article PDF–1.4M

Select item 426388510.

Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity

Andreas K. Hock, Arnaud M. Vigneron, Karen H. Vousden

J Biol Chem. 2014 Dec 12; 289(50): 34862–34870. Published online 2014 Oct 21. doi: 10.1074/jbc.M114.589267

PMCID:: PMC4263885

Abstract Article PDF–2.2M

Select item 385889711.

The Oncogenic Polycomb Histone Methyltransferase EZH2 Methylates Lysine 120 on Histone H2B and Competes Ubiquitination

Masaharu Kogure, Masashi Takawa, Vassiliki Saloura, Kenbun Sone, Lianhua Piao, Koji Ueda, Reem Ibrahim, Tatsuhiko Tsunoda, Masanori Sugiyama, Yutaka Atomi, Yusuke Nakamura, Ryuji Hamamoto

Neoplasia. 2013 Nov; 15(11): 1251–1261. doi: 10.1593/neo.131436

PMCID:: PMC3858897

Abstract Article PDF–4.1M

Select item 323315812.

Core Histones H2B and H4 Are Mobilized during Infection with Herpes Simplex Virus 1

Kristen L. Conn, Michael J. Hendzel, Luis M. Schang

J Virol. 2011 Dec; 85(24): 13234–13252. doi: 10.1128/JVI.06038-11

PMCID:: PMC3233158

Abstract Article PDF–3.9M

Select item 769367913.

HIV-Infected Patients: Cross Site-Specific Hydrolysis of H2a and H2b Histones and Myelin Basic Protein with Antibodies against These Three Proteins

Svetlana V. Baranova, Pavel S. Dmitrienok, Valentina N. Buneva, Georgy A. Nevinsky

Biomolecules. 2020 Nov; 10(11): 1501. Published online 2020 Oct 30. doi: 10.3390/biom10111501

PMCID:: PMC7693679

Abstract Article PDF–10M

Select item 703555914.

Role of a DEF/Y motif in histone H2A-H2B recognition and nucleosome editing

Yan Huang, Lu Sun, Leonidas Pierrakeas, Linchang Dai, Lu Pan, Ed Luk, Zheng Zhou

Proc Natl Acad Sci U S A. 2020 Feb 18; 117(7): 3543–3550. Published online 2020 Jan 30. doi: 10.1073/pnas.1914313117

PMCID:: PMC7035559

Abstract Article PDF–1.9M

Select item 560025815.

let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery

Ambra Spolverini, Gilad Fuchs, Débora Rosa Bublik, Moshe Oren

Oncogene. Author manuscript; available in PMC 2017 Dec 12.

Published in final edited form as: Oncogene. 2017 Oct 19; 36(42): 5819–5828. Published online 2017 Jun 12. doi: 10.1038/onc.2017.187

PMCID:: PMC5600258

Abstract Article PDF–1.9M

Select item 508705016.

Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition

Siming Zhao, Stefania Bellone, Salvatore Lopez, Durga Thakral, Carlton Schwab, Diana P. English, Jonathan Black, Emiliano Cocco, Jungmin Choi, Luca Zammataro, Federica Predolini, Elena Bonazzoli, Mark Bi, Natalia Buza, Pei Hui, Serena Wong, Maysa Abu-Khalaf, Antonella Ravaggi, Eliana Bignotti, Elisabetta Bandiera, Chiara Romani, Paola Todeschini, Renata Tassi, Laura Zanotti, Franco Odicino, Sergio Pecorelli, Carla Donzelli, Laura Ardighieri, Fabio Facchetti, Marcella Falchetti, Dan-Arin Silasi, Elena Ratner, Masoud Azodi, Peter E. Schwartz, Shrikant Mane, Roberto Angioli, Corrado Terranova, Charles Matthew Quick, Babak Edraki, Kaya Bilgüvar, Moses Lee, Murim Choi, Amy L. Stiegler, Titus J. Boggon, Joseph Schlessinger, Richard P. Lifton, Alessandro D. Santin

Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43): 12238–12243. Published online 2016 Oct 10. doi: 10.1073/pnas.1614120113

PMCID:: PMC5087050

Abstract Article PDF–935K

Select item 492024917.

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4⁺ T cells through p65 and H2B phosphorylation

Jasmine Li, Kristine Hardy, Chan Phetsouphanh, Wen Juan Tu, Elissa L. Sutcliffe, Robert McCuaig, Christopher R. Sutton, Anjum Zafar, C. Mee Ling Munier, John J. Zaunders, Yin Xu, Angelo Theodoratos, Abel Tan, Pek Siew Lim, Tobias Knaute, Antonia Masch, Johannes Zerweck, Vedran Brezar, Peter J. Milburn, Jenny Dunn, Marco G. Casarotto, Stephen J. Turner, Nabila Seddiki, Anthony D. Kelleher, Sudha Rao

J Cell Sci. 2016 Jun 15; 129(12): 2448–2461. doi: 10.1242/jcs.181248

PMCID:: PMC4920249

Abstract Article

Select item 206451718.

A novel histone exchange factor, protein phosphatase 2Cγ, mediates the exchange and dephosphorylation of H2A–H2B

Hiroshi Kimura, Nanako Takizawa, Eric Allemand, Tetsuya Hori, Francisco J. Iborra, Naohito Nozaki, Michiko Muraki, Masatoshi Hagiwara, Adrian R. Krainer, Tatsuo Fukagawa, Katsuya Okawa

J Cell Biol. 2006 Nov 6; 175(3): 389–400. doi: 10.1083/jcb.200608001

PMCID:: PMC2064517

Abstract Article PDF–3.4M

Select item 144083719.

Nucleolin is a histone chaperone with FACT-like activity and assists remodeling of nucleosomes

Dimitar Angelov, Vladimir A Bondarenko, Sébastien Almagro, Hervé Menoni, Fabien Mongélard, Fabienne Hans, Flore Mietton, Vasily M Studitsky, Ali Hamiche, Stefan Dimitrov, Philippe Bouvet

EMBO J. 2006 Apr 19; 25(8): 1669–1679. Published online 2006 Apr 6. doi: 10.1038/sj.emboj.7601046

PMCID:: PMC1440837

Abstract Article PDF–316K

Select item 2791020.

Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane

Islam U. Khan, Reidar Wallin, Radhey S. Gupta, Gary M. Kammer

Proc Natl Acad Sci U S A. 1998 Sep 1; 95(18): 10425–10430. doi: 10.1073/pnas.95.18.10425

PMCID:: PMC27910

Abstract Article PDF–283K

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