PMC Links for Gene (Select 83504) - PMC

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Select item 98624421.

Klotho Regulated by Estrogen Plays a Key Role in Sex Differences in Stress Resilience in Rats

Zhinei Tan, Yongxia Li, Yinzheng Guan, Javed Iqbal, Chenyue Wang, Riqiang Yan, Xin-Ming Ma

Int J Mol Sci. 2023 Jan; 24(2): 1206. Published online 2023 Jan 7. doi: 10.3390/ijms24021206

PMCID:: PMC9862442

Abstract Article PDF–2.6M

Select item 98403392.

Androgen increases klotho expression via the androgen receptor-mediated pathway to induce GCs apoptosis

Xin Zeng, Qiaoqing Zhong, Ming Li, Yating Liu, Shuanglian long, Yuanjie Xie, Zhongcheng Mo

J Ovarian Res. 2023; 16: 10. Published online 2023 Jan 14. doi: 10.1186/s13048-022-01087-w

PMCID:: PMC9840339

Abstract Article PDF–8.7M

Select item 90145713.

Impact of klotho on the expression of SRGAP2a in podocytes in diabetic nephropathy

Donghua Jin, Miao Jia, Yuxian Xie, Lihua Lin, Hong Qiu, Guoyuan Lu

BMC Nephrol. 2022; 23: 151. Published online 2022 Apr 18. doi: 10.1186/s12882-022-02765-z

PMCID:: PMC9014571

Abstract Article PDF–5.4M

Select item 83459724.

Role of Klotho in Hyperglycemia: Its Levels and Effects on Fibroblast Growth Factor Receptors, Glycolysis, and Glomerular Filtration

Marlena Typiak, Tomasz Kulesza, Patrycja Rachubik, Dorota Rogacka, Irena Audzeyenka, Stefan Angielski, Moin A. Saleem, Agnieszka Piwkowska

Int J Mol Sci. 2021 Aug; 22(15): 7867. Published online 2021 Jul 23. doi: 10.3390/ijms22157867

PMCID:: PMC8345972

Abstract Article PDF–2.5M

Select item 79867265.

Klotho Regulates Epithelial-to-Mesenchymal Transition In Vitro via Wnt/β-Catenin Pathway and Attenuates Chronic Allograft Dysfunction in a Rat Renal Transplant Model

Xiao-Jun Li, Pei Lu, Xue-Feng Shao, Ting Jiang, Feng Liu, Gang Li

Ann Transplant. 2021; 26: e930066-1–e930066-8. Prepublished online 2021 Feb 22. Published online 2021 Mar 19. doi: 10.12659/AOT.930066

PMCID:: PMC7986726

Abstract Article PDF–1.1M

Select item 69980596.

Salusin-β Promotes Vascular Calcification via Nicotinamide Adenine Dinucleotide Phosphate/Reactive Oxygen Species-Mediated Klotho Downregulation

Haijian Sun, Feng Zhang, Yu Xu, Shuo Sun, Huiping Wang, Qiong Du, Chenxin Gu, Stephen M. Black, Ying Han, Haiyang Tang

Antioxid Redox Signal. 2019 Dec 20; 31(18): 1352–1370. Published online 2019 Nov 13. doi: 10.1089/ars.2019.7723

PMCID:: PMC6998059

Abstract Article PDF–2.8M

Select item 37568297.

Expression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood

Sarah M. Clinton, Matthew E. Glover, Astha Maltare, Ann M. Laszczyk, Stephen J. Mehi, Rebecca K. Simmons, Gwendalyn D. King

Brain Res. Author manuscript; available in PMC 2014 Aug 21.

Published in final edited form as: Brain Res. 2013 Aug 21; 1527: 1–14. Published online 2013 Jul 6. doi: 10.1016/j.brainres.2013.06.044

PMCID:: PMC3756829

Abstract Article PDF–2.8M

Select item 34464828.

The effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells

Akihiko Hiyama, Fumiyuki Arai, Daisuke Sakai, Katsuya Yokoyama, Joji Mochida

Arthritis Res Ther. 2012; 14(3): R105. Published online 2012 May 2. doi: 10.1186/ar3830

PMCID:: PMC3446482

Abstract Article PDF–1.0M

Select item 31686009.

Zhong Zuo, Han Lei, Xiuqing Wang, Yuhong Wang, William Sonntag, Zhongjie Sun

Age (Dordr) 2011 Sep; 33(3): 261–274. Published online 2010 Sep 10. doi: 10.1007/s11357-010-9176-2

PMCID:: PMC3168600

Abstract Article PDF–701K

Select item 289669310.

Decrease of Klotho in the Kidney of Streptozotocin-Induced Diabetic Rats

Meng-Fu Cheng, Li-Jen Chen, Juei-Tang Cheng

J Biomed Biotechnol. 2010; 2010: 513853. Published online 2010 Jun 27. doi: 10.1155/2010/513853

PMCID:: PMC2896693

Abstract Article PDF–2.7M

Select item 214837811.

Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

Ci-Di Chen, Sonia Podvin, Earl Gillespie, Susan E. Leeman, Carmela R. Abraham

Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50): 19796–19801. Published online 2007 Dec 3. doi: 10.1073/pnas.0709805104

PMCID:: PMC2148378

Abstract Article PDF–774K

Select item 1114711812.

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases

R. Nagai*, Y. Saito, Y. Ohyama, H. Aizawa, T. Suga, T. Nakamura, M. Kurabayashi, M. Kuro-o

Cell Mol Life Sci. 2000 May; 57(5): 738–746. doi: 10.1007/s000180050038

PMCID:: PMC11147118

Abstract PDF–289K

Select item 859647313.

SIRT1 and Klotho expression in the heart and kidneys of rats with acute and chronic renovascular hypertension

Mahboobeh Yeganeh-Hajahmadi, Hamid Najafipour, Farzaneh Rostamzadeh, Yaser Masoumi-Ardakani

Croat Med J. 2021 Oct; 62(5): 504–512. doi: 10.3325/cmj.2021.62.504

PMCID:: PMC8596473

Abstract Article PDF–2.4M

Select item 603191714.

Klotho and activin A in kidney injury: plasma Klotho is maintained in unilateral obstruction despite no upregulation of Klotho biosynthesis in the contralateral kidney

Anders Nordholm, Maria L. Mace, Eva Gravesen, Jacob Hofman-Bang, Marya Morevati, Klaus Olgaard, Ewa Lewin

Am J Physiol Renal Physiol. 2018 May 1; 314(5): F753–F762. Published online 2017 Nov 29. doi: 10.1152/ajprenal.00528.2017

PMCID:: PMC6031917

Abstract Article

Select item 587610115.

Alpha-Klotho Enrichment in Induced Pluripotent Stem Cell Secretome Contributes to Antioxidative Protection in Acute Lung Injury

Amiq Gazdhar, Priya Ravikumar, Johanne Pastor, Manfred Heller, Jianfeng Ye, Jianning Zhang, Orson W. Moe, Thomas Geiser, Connie C.W. Hsia

Stem Cells. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Stem Cells. 2018 Apr; 36(4): 616–625. Published online 2017 Dec 25. doi: 10.1002/stem.2752

PMCID:: PMC5876101

Abstract Article PDF–665K

Select item 557219116.

Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily exercise and caloric restriction

Justin A. Fletcher, Grace M. Meers, M. Harold Laughlin, Jamal A. Ibdah, John P. Thyfault, R. Scott Rector

Appl Physiol Nutr Metab. Author manuscript; available in PMC 2017 Aug 28.

Published in final edited form as: Appl Physiol Nutr Metab. 2012 Dec; 37(6): 1054–1062. Published online 2012 Aug 15. doi: 10.1139/h2012-091

PMCID:: PMC5572191

Abstract Article PDF–903K

Select item 443893917.

Klotho gene delivery ameliorates renal hypertrophy and fibrosis in streptozotocin-induced diabetic rats by suppressing the Rho-associated coiled-coil kinase signaling pathway

MINGHONG DENG, YUMEI LUO, YUNKUI LI, QIUCHEN YANG, XIAOQIN DENG, PING WU, HOUXUN MA

Mol Med Rep. 2015 Jul; 12(1): 45–54. Published online 2015 Feb 17. doi: 10.3892/mmr.2015.3367

PMCID:: PMC4438939

Abstract Article PDF–2.0M

Select item 397232018.

Klotho has dual protective effects on cisplatin-induced acute kidney injury

Monica Chang Panesso, Mingjun Shi, Han Ju Cho, Jean Paek, Jianfeng Ye, Orson W. Moe, Ming Chang Hu

Kidney Int. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Kidney Int. 2014 Apr; 85(4): 855–870. Published online 2013 Dec 4. doi: 10.1038/ki.2013.489

PMCID:: PMC3972320

Abstract Article PDF–4.1M

Select item 374389919.

Renal Expression of FGF23 in Progressive Renal Disease of Diabetes and the Effect of Ace Inhibitor

Cristina Zanchi, Monica Locatelli, Ariela Benigni, Daniela Corna, Susanna Tomasoni, Daniela Rottoli, Flavio Gaspari, Giuseppe Remuzzi, Carlamaria Zoja

PLoS One. 2013; 8(8): e70775. Published online 2013 Aug 14. doi: 10.1371/journal.pone.0070775

PMCID:: PMC3743899

Abstract Article PDF–5.1M

Select item 371138820.

The Antiaging Protein Klotho Enhances Oligodendrocyte Maturation and Myelination of the CNS

Ci-Di Chen, Jacob A. Sloane, Hu Li, Nurgul Aytan, Eustathia L. Giannaris, Ella Zeldich, Jason D. Hinman, Alpaslan Dedeoglu, Douglas L. Rosene, Rashmi Bansal, Jennifer I. Luebke, Makoto Kuro-o, Carmela R. Abraham

J Neurosci. 2013 Jan 30; 33(5): 1927–1939. doi: 10.1523/JNEUROSCI.2080-12.2013

PMCID:: PMC3711388

Abstract Article PDF–1.8M

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PMC Links for Gene (Select 83504) (32)
PMC
uncharacterized protein Dwil_GK21592 [Drosophila willistoni]
uncharacterized protein Dwil_GK21592 [Drosophila willistoni]
gi|194159126|gnl|WGS:AAQB|GK21592-P EDW74027.1|

Protein
ventricular zone-expressed PH domain-containing protein [Danio rerio]
ventricular zone-expressed PH domain-containing protein [Danio rerio]
gi|47086371|ref|NP_997996.1|

Protein
Nucleotide Links for Gene (Select 128078759) (7)
Nucleotide
Mus musculus targeted KO-first, conditional ready, lacZ-tagged mutant allele Chs...
Mus musculus targeted KO-first, conditional ready, lacZ-tagged mutant allele Chst8:tm1a(KOMP)Ucd; transgenic
gi|354797184|gb|JN961685.1|

Nucleotide

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