PMC Links for Gene (Select 84033) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 56

<< First< Prev

Page of 3

Select item 75326771.

Intracellular calcium current disorder and disease phenotype in OBSCN mutant iPSC-based cardiomyocytes in arrhythmogenic right ventricular cardiomyopathy

Peipei Chen, Ying Xiao, Yuanpin Wang, Zhifa Zheng, Lianfeng Chen, Xufei Yang, Jingyi Li, Wei Wu, Shuyang Zhang

Theranostics. 2020; 10(24): 11215–11229. Published online 2020 Sep 14. doi: 10.7150/thno.45172

PMCID:: PMC7532677

Abstract Article PDF–2.8M

Select item 64237192.

Obscurin is a semi‐flexible molecule in solution

Jacob A. Whitley, Aidan M. Ex‐Willey, Daniel R. Marzolf, Maegen A. Ackermann, Anthony L. Tongen, Oleksandr Kokhan, Nathan T. Wright

Protein Sci. 2019 Apr; 28(4): 717–726. Published online 2019 Feb 6. doi: 10.1002/pro.3578

PMCID:: PMC6423719

Abstract Article PDF–922K

Select item 58967643.

Obscurin Variants in Patients With Left Ventricular Noncompaction

Teisha J. Rowland, Sharon L. Graw, Mary E. Sweet, Marta Gigli, Matthew R.G. Taylor, Luisa Mestroni

J Am Coll Cardiol. Author manuscript; available in PMC 2018 Apr 12.

Published in final edited form as: J Am Coll Cardiol. 2016 Nov 15; 68(20): 2237–2238. doi: 10.1016/j.jacc.2016.08.052

PMCID:: PMC5896764

Article PDF–285K

Select item 45831864.

OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency

Steven Marston, Cecile Montgiraud, Alex B. Munster, O’Neal Copeland, Onjee Choi, Cristobal dos Remedios, Andrew E. Messer, Elisabeth Ehler, Ralph Knöll

PLoS One. 2015; 10(9): e0138568. Published online 2015 Sep 25. doi: 10.1371/journal.pone.0138568

PMCID:: PMC4583186

Abstract Article PDF–5.6M

Select item 44262465.

Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis

M Shriver, KM Stroka, MI Vitolo, S Martin, DL Huso, K Konstantopoulos, A Kontrogianni-Konstantopoulos

Oncogene. Author manuscript; available in PMC 2015 Aug 8.

Published in final edited form as: Oncogene. 2015 Aug 6; 34(32): 4248–4259. Published online 2014 Nov 10. doi: 10.1038/onc.2014.358

PMCID:: PMC4426246

Abstract Article PDF–2.2M

Select item 40460986.

Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance

Nicole A. Perry, Marey Shriver, Marie G. Mameza, Bryan Grabias, Eric Balzer, Aikaterini Kontrogianni-Konstantopoulos

FASEB J. 2012 Jul; 26(7): 2764–2775. doi: 10.1096/fj.12-205419

Correction in:: FASEB J. 2012 Sep; 26(9): 3931.

PMCID:: PMC4046098

Abstract Article

Select item 33789587.

Contribution of the OBSCN Nonsynonymous Variants to Aspirin Exacerbated Respiratory Disease Susceptibility in Korean Population

Jeong-Hyun Kim, Byung-Lae Park, Charisse Flerida A. Pasaje, Yongha Kim, Joon Seol Bae, Jong Sook Park, Soo-Taek Uh, Yong-Hoon Kim, Mi-Kyeong Kim, Inseon S. Choi, Sang Heon Cho, Byoung Whui Choi, InSong Koh, Choon-Sik Park, Hyoung Doo Shin

DNA Cell Biol. 2012 Jun; 31(6): 1001–1009. doi: 10.1089/dna.2011.1436

PMCID:: PMC3378958

Abstract Article PDF–528K

Select item 18991688.

Different obscurin isoforms localize to distinct sites at sarcomeres

Amber L Bowman, Aikaterini Kontrogianni-Konstantopoulos, Sara S Hirsch, Sarah B Geisler, Hugo Gonzalez-Serratos, Mark W Russell, Robert J Bloch

FEBS Lett. Author manuscript; available in PMC 2007 Jun 25.

Published in final edited form as: FEBS Lett. 2007 Apr 17; 581(8): 1549–1554. Published online 2007 Mar 15. doi: 10.1016/j.febslet.2007.03.011

PMCID:: PMC1899168

Abstract Article PDF–765K

Select item 94270049.

Giant obscurin regulates migration and metastasis via RhoA-dependent cytoskeletal remodeling in pancreatic cancer

Soontorn Tuntithavornwat, Daniel J. Shea, Bin Sheng Wong, Talia Guardia, Se Jong Lee, Christopher L. Yankaskas, Lei Zheng, Aikaterini Kontrogianni-Konstantopoulos, Konstantinos Konstantopoulos

Cancer Lett. Author manuscript; available in PMC 2022 Aug 30.

Published in final edited form as: Cancer Lett. 2022 Feb 1; 526: 155–167. Published online 2021 Nov 23. doi: 10.1016/j.canlet.2021.11.016

PMCID:: PMC9427004

Abstract Article PDF–2.5M

Select item 565797610.

A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy

Daniela Rossi, Johanna Palmio, Anni Evilä, Lucia Galli, Virginia Barone, Tracy A. Caldwell, Rachel A. Policke, Esraa Aldkheil, Christopher E. Berndsen, Nathan T. Wright, Edoardo Malfatti, Guy Brochier, Enrico Pierantozzi, Albena Jordanova, Velina Guergueltcheva, Norma Beatriz Romero, Peter Hackman, Bruno Eymard, Bjarne Udd, Vincenzo Sorrentino

PLoS One. 2017; 12(10): e0186642. Published online 2017 Oct 26. doi: 10.1371/journal.pone.0186642

PMCID:: PMC5657976

Abstract Article PDF–8.9M

Select item 521673111.

Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit

Marey Shriver, Saravanakumar Marimuthu, Colin Paul, Janelle Geist, Tessa Seale, Konstantinos Konstantopoulos, Aikaterini Kontrogianni-Konstantopoulos

Oncotarget. 2016 Jul 19; 7(29): 45414–45428. Published online 2016 Jun 13. doi: 10.18632/oncotarget.9985

PMCID:: PMC5216731

Abstract Article PDF–9.3M

Select item 422670412.

Loss of the obscurin-RhoGEF downregulates RhoA signaling and increases microtentacle formation and attachment of breast epithelial cells

Nicole A. Perry, Michele I. Vitolo, Stuart S. Martin, Aikaterini Kontrogianni-Konstantopoulos

Oncotarget. 2014 Sep; 5(18): 8558–8568. Published online 2014 Aug 10. doi: 10.18632/oncotarget.2338

PMCID:: PMC4226704

Abstract Article PDF–2.9M

Select item 290447213.

TC10 controls human myofibril organization and is activated by the sarcomeric RhoGEF obscurin

Marjorie Coisy-Quivy, Olivia Touzet, Annick Bourret, Robert A. Hipskind, Jacques Mercier, Philippe Fort, Alexandre Philips

J Cell Sci. Author manuscript; available in PMC 2010 Jul 15.

Published in final edited form as: J Cell Sci. 2009 Apr; 122(Pt 7): 947–956. Published online 2009 Mar 3. doi: 10.1242/jcs.040121

PMCID:: PMC2904472

Abstract Article

Select item 180551714.

Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas

Nathan D. Price, Jonathan Trent, Adel K. El-Naggar, David Cogdell, Ellen Taylor, Kelly K. Hunt, Raphael E. Pollock, Leroy Hood, Ilya Shmulevich, Wei Zhang

Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9): 3414–3419. Published online 2007 Feb 21. doi: 10.1073/pnas.0611373104

PMCID:: PMC1805517

Abstract Article PDF–463K

Select item 818840515.

When is an obscurin variant pathogenic? The impact of Arg4344Gln and Arg4444Trp variants on protein–protein interactions and protein stability

Atsushi Fukuzawa, Daniel Koch, Sarah Grover, Martin Rees, Mathias Gautel

Hum Mol Genet. 2021 Jun 15; 30(12): 1131–1141. Published online 2021 Jan 12. doi: 10.1093/hmg/ddab010

PMCID:: PMC8188405

Abstract Article PDF–1.3M

Select item 522258816.

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection

Stefano Pernigo, Atsushi Fukuzawa, Amy E.M. Beedle, Mark Holt, Adam Round, Alessandro Pandini, Sergi Garcia-Manyes, Mathias Gautel, Roberto A. Steiner

Structure. 2017 Jan 3; 25(1): 107–120. doi: 10.1016/j.str.2016.11.015