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Select item 54125651.

The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome

Abdelhalim Loukil, Kati Tormanen, Christine Sütterlin

J Cell Biol. 2017 May 1; 216(5): 1287–1300. doi: 10.1083/jcb.201608119

PMCID:: PMC5412565

Abstract Article PDF–2.1M

Select item 89325232.

Neuralized-like protein 4 (NEURL4) mediates ADP-ribosylation of mitochondrial proteins

Maria Dafne Cardamone, Yuan Gao, Julian Kwan, Vanessa Hayashi, Megan Sheeran, Junxiang Xu, Justin English, Joseph Orofino, Andrew Emili, Valentina Perissi

J Cell Biol. 2022 Mar 7; 221(3): e202101021. Published online 2022 Feb 2. doi: 10.1083/jcb.202101021

PMCID:: PMC8932523

Abstract Article PDF–3.3M

Select item 56174673.

NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization

Monica Cubillos-Rojas, Taiane Schneider, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa

Oncotarget. 2017 Sep 5; 8(37): 61824–61836. Published online 2017 Jun 27. doi: 10.18632/oncotarget.18699

PMCID:: PMC5617467

Abstract Article PDF–5.9M

Select item 69441184.

Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2

Jesús García‐Cano, Susana Sánchez‐Tena, Joan Sala‐Gaston, Agnès Figueras, Francesc Viñals, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa

Mol Oncol. 2020 Jan; 14(1): 69–86. Published online 2019 Nov 15. doi: 10.1002/1878-0261.12592

PMCID:: PMC6944118

Abstract Article PDF–2.4M

Select item 33672365.

Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres

Ji Li, Sehyun Kim, Tetsuo Kobayashi, Feng-Xia Liang, Nina Korzeniewski, Stefan Duensing, Brian D Dynlacht

EMBO Rep. 2012 Jun; 13(6): 547–553. Published online 2012 Mar 23. doi: 10.1038/embor.2012.40

PMCID:: PMC3367236

Abstract Article PDF–1008K

Select item 38155296.

USP33 regulates centrosome biogenesis via de-ubiquitylation of a centriolar protein, CP110

Ji Li, Vincenzo D’Angiolella, E. Scott Seeley, Sehyun Kim, Tetsuo Kobayashi, Wenxiang Fu, Eric I Campos, Michele Pagano, Brian David Dynlacht

Nature. Author manuscript; available in PMC 2013 Nov 3.

Published in final edited form as: Nature. 2013 Mar 14; 495(7440): 10.1038/nature11941. doi: 10.1038/nature11941

PMCID:: PMC3815529

Abstract Article PDF–2.0M

Select item 45656727.

The Parkinson’s Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway

Yuzuru Imai, Yoshito Kobayashi, Tsuyoshi Inoshita, Hongrui Meng, Taku Arano, Kengo Uemura, Takeshi Asano, Kenji Yoshimi, Chang-Liang Zhang, Gen Matsumoto, Toshiyuki Ohtsuka, Ryoichiro Kageyama, Hiroshi Kiyonari, Go Shioi, Nobuyuki Nukina, Nobutaka Hattori, Ryosuke Takahashi

PLoS Genet. 2015 Sep; 11(9): e1005503. Published online 2015 Sep 10. doi: 10.1371/journal.pgen.1005503

PMCID:: PMC4565672

Abstract Article PDF–11M

Select item 34339078.

Interaction Proteomics Identify NEURL4 and the HECT E3 Ligase HERC2 as Novel Modulators of Centrosome Architecture

Abdallah K. Al-Hakim, Mikhail Bashkurov, Anne-Claude Gingras, Daniel Durocher, Laurence Pelletier

Mol Cell Proteomics. 2012 Jun; 11(6): M111.014233. Published online 2012 Jan 20. doi: 10.1074/mcp.M111.014233

PMCID:: PMC3433907

Abstract Article PDF–1.8M

Select item 62543569.

Angelman syndrome–associated point mutations in the Zn²⁺-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome

Simone Kühnle, Gustavo Martínez-Noël, Flavien Leclere, Sebastian D. Hayes, J. Wade Harper, Peter M. Howley

J Biol Chem. 2018 Nov 23; 293(47): 18387–18399. Published online 2018 Sep 26. doi: 10.1074/jbc.RA118.004653

PMCID:: PMC6254356

Abstract Article PDF–1.3M

Select item 343450810.

Identification and Proteomic Analysis of Distinct UBE3A/E6AP Protein Complexes

Gustavo Martínez-Noël, Jeffrey T. Galligan, Mathew E. Sowa, Verena Arndt, Thomas M. Overton, J. Wade Harper, Peter M. Howley

Mol Cell Biol. 2012 Aug; 32(15): 3095–3106. doi: 10.1128/MCB.00201-12

PMCID:: PMC3434508

Abstract Article PDF–2.1M

Select item 586679011.

Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes

Gustavo Martínez-Noël, Katja Luck, Simone Kühnle, Alice Desbuleux, Patricia Szajner, Jeffrey T. Galligan, Diana Rodriguez, Leon Zheng, Kathleen Boyland, Flavian Leclere, Quan Zhong, David E. Hill, Marc Vidal, Peter M. Howley

J Mol Biol. Author manuscript; available in PMC 2019 Mar 30.

Published in final edited form as: J Mol Biol. 2018 Mar 30; 430(7): 1024–1050. Published online 2018 Feb 6. doi: 10.1016/j.jmb.2018.01.021

PMCID:: PMC5866790

Abstract Article PDF–4.1M

Select item 432443912.

Proteomic Analysis and Identification of Cellular Interactors of the Giant Ubiquitin Ligase HERC2

Jeffrey T. Galligan, Gustavo Martinez-Noël, Verena Arndt, Sebastian Hayes, Thomas W. Chittenden, J. Wade Harper, Peter M. Howley

J Proteome Res. 2015 Feb 6; 14(2): 953–966. Published online 2014 Dec 4. doi: 10.1021/pr501005v

PMCID:: PMC4324439

Abstract Article PDF–7.5M

Select item 796299413.

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

Yanke Chen, Ting Jiang, Hongyi Zhang, Xingchun Gou, Cong Han, Jianhui Wang, Ann T. Chen, Jun Ma, Jun Liu, Zeming Chen, Xintao Jing, Hong Lei, Zhenzhen Wang, Youmei Bao, Mehdi Baqri, Yong Zhu, Ranjit S. Bindra, James E. Hansen, Jun Dou, Chen Huang, Jiangbing Zhou

Nat Cell Biol. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Nat Cell Biol. 2020 Oct; 22(10): 1276–1285. Published online 2020 Oct 1. doi: 10.1038/s41556-020-00586-6

PMCID:: PMC7962994

Abstract Article PDF–5.5M

Select item 794896414.

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1

Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi

J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162

PMCID:: PMC7948964

Abstract Article PDF–2.7M

Select item 825771215.

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates

David Schlütermann, Niklas Berleth, Jana Deitersen, Nora Wallot-Hieke, Olena Friesen, Wenxian Wu, Fabian Stuhldreier, Yadong Sun, Lena Berning, Annabelle Friedrich, María José Mendiburo, Christoph Peter, Constanze Wiek, Helmut Hanenberg, Anja Stefanski, Kai Stühler, Björn Stork

Sci Rep. 2021; 11: 13863. Published online 2021 Jul 5. doi: 10.1038/s41598-021-92408-4

PMCID:: PMC8257712

Abstract Article PDF–3.2M

Select item 1049982116.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 584026617.

Insights into the ubiquitin-proteasome system of human embryonic stem cells

Isabel Saez, Seda Koyuncu, Ricardo Gutierrez-Garcia, Christoph Dieterich, David Vilchez

Sci Rep. 2018; 8: 4092. Published online 2018 Mar 6. doi: 10.1038/s41598-018-22384-9

PMCID:: PMC5840266

Abstract Article PDF–2.9M

Select item 821018418.

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma

Verónica Freire-Benéitez, Nicola Pomella, Thomas O Millner, Anaëlle A Dumas, Maria Victoria Niklison-Chirou, Eleni Maniati, Jun Wang, Vinothini Rajeeve, Pedro Cutillas, Silvia Marino

NAR Cancer. 2021 Mar; 3(1): zcab009. Published online 2021 Mar 22. doi: 10.1093/narcan/zcab009

Correction in:: NAR Cancer. 2021 Jun; 3(2): zcab020.

PMCID:: PMC8210184

Abstract Article PDF–3.4M

Select item 876907219.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 637572920.

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains

Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras

Mol Cell. 2019 Feb 7; 73(3): 621–638.e17. doi: 10.1016/j.molcel.2018.11.006