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Select item 105322491.

A Decrease in Maternal Iron Levels Is the Predominant Factor Suppressing Hepcidin during Pregnancy in Mice

Sheridan L. Helman, Sarah J. Wilkins, Jennifer C. J. Chan, Gunter Hartel, Daniel F. Wallace, Gregory J. Anderson, David M. Frazer

Int J Mol Sci. 2023 Sep; 24(18): 14379. Published online 2023 Sep 21. doi: 10.3390/ijms241814379

PMCID:: PMC10532249

Abstract Article PDF–2.0M

Select item 104068282.

Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis

Jean-Christophe Deschemin, Céline Ransy, Frédéric Bouillaud, Soonkyu Chung, Bruno Galy, Carole Peyssonnaux, Sophie Vaulont

Sci Rep. 2023; 13: 12794. Published online 2023 Aug 7. doi: 10.1038/s41598-023-39305-0

PMCID:: PMC10406828

Abstract Article PDF–7.0M

Select item 88357433.

Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury

Laura E. Diepeveen, Gaby Stegemann, Erwin T. Wiegerinck, Rian Roelofs, Myrthe Naber, Olivier Lóreal, Bart Smeets, Frank Thévenod, Dorine W. Swinkels, Rachel P. L. van Swelm

Int J Mol Sci. 2022 Feb; 23(3): 1352. Published online 2022 Jan 25. doi: 10.3390/ijms23031352

PMCID:: PMC8835743

Abstract Article PDF–2.2M

Select item 87520874.

Aging is associated with increased brain iron through cortex-derived hepcidin expression

Tatsuya Sato, Jason Solomon Shapiro, Hsiang-Chun Chang, Richard A Miller, Hossein Ardehali

eLife. 2022; 11: e73456. Published online 2022 Jan 11. doi: 10.7554/eLife.73456

PMCID:: PMC8752087

Abstract Article PDF–926K

Select item 83574695.

Involvement of Hepcidin in Cognitive Damage Induced by Chronic Intermittent Hypoxia in Mice

Ya-Shuo Zhao, Miao Tan, Ji-Xian Song, Ji-Ren An, Xin-Yue Yang, Wen-Ya Li, Ya-Jing Guo, En-Sheng Ji

Oxid Med Cell Longev. 2021; 2021: 8520967. Published online 2021 Aug 4. doi: 10.1155/2021/8520967

PMCID:: PMC8357469

Abstract Article PDF–3.9M

Select item 78054846.

Hepcidin is essential for alveolar macrophage function and is disrupted by smoke in a murine COPD model

Elizabeth Perez, Jonathan R. Baker, Silvana Di Giandomenico, Pouneh Kermani, Jacqueline Parker, Kihwan Kim, Jianjun Yang, Peter J. Barnes, Sophie Vaulont, Joseph M. Scandura, Louise E. Donnelly, Heather Stout-Delgado, Suzanne M. Cloonan

J Immunol. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: J Immunol. 2020 Nov 1; 205(9): 2489–2498. Published online 2020 Sep 21. doi: 10.4049/jimmunol.1901284

PMCID:: PMC7805484

Abstract Article PDF–1.3M

Select item 77545347.

Adenine alleviates iron overload by cAMP/PKA mediated hepatic hepcidin in mice

Yingqi Zhang, Xudong Wang, Qian Wu, Hao Wang, Lu Zhao, Xinhui Wang, Mingdao Mu, Enjun Xie, Xuyan He, Dandan Shao, Yanna Shang, Yongrong Lai, Yelena Ginzburg, Junxia Min, Fudi Wang

J Cell Physiol. Author manuscript; available in PMC 2020 Dec 22.

Published in final edited form as: J Cell Physiol. 2018 Sep; 233(9): 7268–7278. Published online 2018 Mar 30. doi: 10.1002/jcp.26559

PMCID:: PMC7754534

Abstract Article PDF–1.9M

Select item 67983108.

Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice

Wanting Shu, Bailey H. Baumann, Ying Song, Yingrui Liu, Xingwei Wu, Joshua L. Dunaief

Invest Ophthalmol Vis Sci. 2019 Oct; 60(13): 4378–4387. doi: 10.1167/iovs.19-28250

PMCID:: PMC6798310

Abstract Article PDF–1.5M

Select item 67119539.

Fractalkine Induces Hepcidin Expression of BV-2 Microglia and Causes Iron Accumulation in SH-SY5Y Cells

Edina Pandur, Kitti Tamási, Ramóna Pap, Edit Varga, Attila Miseta, Katalin Sipos

Cell Mol Neurobiol. 2019; 39(7): 985–1001. Published online 2019 Jun 6. doi: 10.1007/s10571-019-00694-4

PMCID:: PMC6711953

Abstract Article PDF–3.0M

Select item 658025010.

Dietary restriction of iron availability attenuates UPEC pathogenesis in a mouse model of urinary tract infection

Kyle A. Bauckman, Rina Matsuda, Cassandra B. Higgins, Brian J. DeBosch, Caihong Wang, Indira U. Mysorekar

Am J Physiol Renal Physiol. 2019 May 1; 316(5): F814–F822. Published online 2019 Feb 6. doi: 10.1152/ajprenal.00133.2018

PMCID:: PMC6580250

Abstract Article

Select item 616579311.

Circulating iron levels influence the regulation of hepcidin following stimulated erythropoiesis

Cornel S.G. Mirciov, Sarah J. Wilkins, Grace C. C. Hung, Sheridan L. Helman, Gregory J. Anderson, David M. Frazer

Haematologica. 2018 Oct; 103(10): 1616–1626. Prepublished online 2018 Jun 14. doi: 10.3324/haematol.2017.187245

PMCID:: PMC6165793

Abstract Article PDF–1.1M

Select item 594578012.

Endogenous hepcidin synthesis protects the distal nephron against hemin and hemoglobin mediated necroptosis

Rachel P. L. van Swelm, Madelon Vos, Frank Verhoeven, Frank Thévenod, Dorine W. Swinkels

Cell Death Dis. 2018 May; 9(5): 550. Published online 2018 May 10. doi: 10.1038/s41419-018-0568-z

PMCID:: PMC5945780

Abstract Article PDF–2.1M

Select item 579221613.

Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice

Stela McLachlan, Kathryn E. Page, Seung-Min Lee, Alex Loguinov, Erika Valore, Simon T. Hui, Grace Jung, Jie Zhou, Aldons J. Lusis, Brie Fuqua, Tomas Ganz, Elizabeta Nemeth, Chris D. Vulpe

Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1; 313(5): G511–G523. Published online 2017 Aug 10. doi: 10.1152/ajpgi.00307.2016

PMCID:: PMC5792216

Abstract Article

Select item 576437314.

Hepcidin deficiency and iron deficiency do not alter tuberculosis susceptibility in a murine M.tb infection model

Rachel Harrington-Kandt, Elena Stylianou, Lucy A. Eddowes, Pei Jin Lim, Lisa Stockdale, Nawamin Pinpathomrat, Naomi Bull, Janet Pasricha, Marta Ulaszewska, Yulia Beglov, Sophie Vaulont, Hal Drakesmith, Helen McShane

PLoS One. 2018; 13(1): e0191038. Published online 2018 Jan 11. doi: 10.1371/journal.pone.0191038

PMCID:: PMC5764373

Abstract Article PDF–4.0M

Select item 552047215.

Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non–transferrin-bound iron

Deborah Stefanova, Antoan Raychev, Joao Arezes, Piotr Ruchala, Victoria Gabayan, Mikael Skurnik, Barbara J. Dillon, Marcus A. Horwitz, Tomas Ganz, Yonca Bulut, Elizabeta Nemeth

Blood. 2017 Jul 20; 130(3): 245–257. Prepublished online 2017 May 2. doi: 10.1182/blood-2017-03-772715

PMCID:: PMC5520472

Abstract Article

Select item 541062716.

Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella Infection

Alexandra Willemetz, Sean Beatty, Etienne Richer, Aude Rubio, Anne Auriac, Ruth J. Milkereit, Olivier Thibaudeau, Sophie Vaulont, Danielle Malo, François Canonne-Hergaux

Front Immunol. 2017; 8: 498. Published online 2017 May 1. doi: 10.3389/fimmu.2017.00498

PMCID:: PMC5410627

Abstract Article PDF–3.2M

Select item 539496217.

Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model

Mark R. Hanudel, Maxime Rappaport, Victoria Gabayan, Grace Jung, Isidro B. Salusky, Elizabeta Nemeth, Tomas Ganz, Joshua Zaritsky

Haematologica. 2017 Mar; 102(3): e85–e88. Prepublished online 2016 Nov 22. doi: 10.3324/haematol.2016.150433

PMCID:: PMC5394962

Article PDF–1.2M

Select item 532258318.

Induced Disruption of the Iron-Regulatory Hormone Hepcidin Inhibits Acute Inflammatory Hypoferraemia

Andrew E. Armitage, Pei Jin Lim, Joe N. Frost, Sant-Rayn Pasricha, Elizabeth J. Soilleux, Emma Evans, Alireza Morovat, Ana Santos, Rebeca Diaz, Daniel Biggs, Benjamin Davies, Uzi Gileadi, Peter A. Robbins, Samira Lakhal-Littleton, Hal Drakesmith

J Innate Immun. 2016 Aug; 8(5): 517–528. Published online 2016 Jul 16. doi: 10.1159/000447713

PMCID:: PMC5322583

Abstract Article PDF–455K

Select item 517635419.

An essential cell-autonomous role for hepcidin in cardiac iron homeostasis

Samira Lakhal-Littleton, Magda Wolna, Yu Jin Chung, Helen C Christian, Lisa C Heather, Marcella Brescia, Vicky Ball, Rebeca Diaz, Ana Santos, Daniel Biggs, Kieran Clarke, Benjamin Davies, Peter A Robbins

eLife. 2016; 5: e19804. Published online 2016 Nov 29. doi: 10.7554/eLife.19804

PMCID:: PMC5176354

Abstract Article PDF–5.6M

Select item 513045320.

Lack of hepcidin ameliorates anemia and improves growth in an adenine-induced mouse model of chronic kidney disease

Oleh Akchurin, Angara Sureshbabu, Steve B. Doty, Yuan-Shan Zhu, Edwin Patino, Susanna Cunningham-Rundles, Mary E. Choi, Adele Boskey, Stefano Rivella

Am J Physiol Renal Physiol. 2016 Nov 1; 311(5): F877–F889. Published online 2016 Jul 20. doi: 10.1152/ajprenal.00089.2016

PMCID:: PMC5130453

Abstract Article

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PMC Links for Gene (Select 84506) (150)
PMC
gastrokine-1 precursor [Homo sapiens]
gastrokine-1 precursor [Homo sapiens]
gi|1752938038|ref|NP_062563.4|

Protein
hepcidin preproprotein [Mus musculus]
hepcidin preproprotein [Mus musculus]
gi|14211542|ref|NP_115930.1|

Protein

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