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Select item 100621231.

KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle

Danielle L. Chappell, Praneet K. Sandhu, Jason P. Wong, Aadra P. Bhatt, Xiaoxi Liu, Sara J. Buhrlage, Brenda R. S. Temple, M. Ben Major, Blossom Damania

J Virol. 2023 Mar; 97(3): e01763-22. Published online 2023 Mar 6. doi: 10.1128/jvi.01763-22

PMCID:: PMC10062123

Abstract Article PDF–2.7M

Select item 61768942.

Discovery and Validation of Methylation Biomarkers for Ulcerative Colitis Associated Neoplasia

Andrew D Beggs, Jonathan James, Germaine Caldwell, Toby Prout, Mark P Dilworth, Phillipe Taniere, Tariq Iqbal, Dion G Morton, Glenn Matthews

Inflamm Bowel Dis. 2018 Jul; 24(7): 1503–1509. Published online 2018 May 14. doi: 10.1093/ibd/izy119

PMCID:: PMC6176894

Abstract Article PDF–446K

Select item 38738953.

A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death

Raul E. Salinas, Cassandra Ogohara, Monica I. Thomas, Kajal P. Shukla, Samuel I. Miller, Dennis C. Ko

Mol Biol Cell. 2014 Jan 1; 25(1): 76–86. doi: 10.1091/mbc.E13-06-0294

PMCID:: PMC3873895

Abstract Article PDF–3.4M

Select item 38704804.

Characterization of a human βV-tubulin antibody and expression of this isotype in normal and malignant human tissue

Suzan K. Chao, Yihong Wang, Pascal Verdier-Pinard, Chia-Ping H. Yang, Lingling Liu, Alicia Rodriguez-Gabin, Hayley M. McDaid, Susan Band Horwitz

Cytoskeleton (Hoboken) Author manuscript; available in PMC 2013 Dec 23.

Published in final edited form as: Cytoskeleton (Hoboken). 2012 Aug; 69(8): 10.1002/cm.21043. Published online 2012 Jul 2. doi: 10.1002/cm.21043

PMCID:: PMC3870480

Abstract Article PDF–3.1M

Select item 38872135.

A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation

Bernard M. H. Law, Victoria A. Spain, Veronica H. L. Leinster, Ruth Chia, Alexandra Beilina, Hyun J. Cho, Jean-Marc Taymans, Mary K. Urban, Rosa M. Sancho, Marian Blanca Ramírez, Saskia Biskup, Veerle Baekelandt, Huaibin Cai, Mark R. Cookson, Daniel C. Berwick, Kirsten Harvey

J Biol Chem. 2014 Jan 10; 289(2): 895–908. Published online 2013 Nov 25. doi: 10.1074/jbc.M113.507913

PMCID:: PMC3887213

Abstract Article PDF–3.8M

Select item 21802226.

HIV-1 Rev Depolymerizes Microtubules to Form Stable Bilayered Rings

Norman R. Watts, Dan L. Sackett, Rita D. Ward, Mill W. Miller, Paul T. Wingfield, Stephen S. Stahl, Alasdair C. Steven

J Cell Biol. 2000 Jul 24; 150(2): 349–360. doi: 10.1083/jcb.150.2.349

PMCID:: PMC2180222

Abstract Article PDF–640K

Select item 93858627.

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2

Jie Wang, Zhiwei He, Xinyuan Liu, Jian Xu, Xueyi Jiang, Gang Quan, Jianxin Jiang

Cell Death Dis. 2022 Aug; 13(8): 718. Published online 2022 Aug 18. doi: 10.1038/s41419-022-05172-2

PMCID:: PMC9385862

Abstract Article PDF–6.6M

Select item 1391038.

HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim

Dan Chen, Michael Wang, Sharleen Zhou, Qiang Zhou

EMBO J. 2002 Dec 16; 21(24): 6801–6810. doi: 10.1093/emboj/cdf683

PMCID:: PMC139103

Abstract Article PDF–343K

Select item 36950419.

Systematic Analysis of the Functions of Lysine Acetylation in the Regulation of Tat Activity

Minghao He, Linlin Zhang, Xincheng Wang, Lihong Huo, Lei Sun, Chengye Feng, Xutian Jing, Danyao Du, Huabin Liang, Min Liu, Zhangyong Hong, Jun Zhou

PLoS One. 2013; 8(6): e67186. Published online 2013 Jun 27. doi: 10.1371/journal.pone.0067186

PMCID:: PMC3695041

Abstract Article PDF–1.8M

Select item 626852410.

c-IAP1 Binds and Processes PCSK9 Protein: Linking the c-IAP1 in a TNF-α Pathway to PCSK9-Mediated LDLR Degradation Pathway

Weiming Xu, Lizhi Liu, David Hornby

Molecules. 2012 Oct; 17(10): 12086–12101. Published online 2012 Oct 15. doi: 10.3390/molecules171012086

PMCID:: PMC6268524

Abstract Article PDF–528K

Select item 829252711.

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui zhang, Qun-Ying Lei, Zhi-min Shao, Xiuwu Bian, Ronggui Hu, Lixing Zhang, Suling Liu

Nat Commun. 2021; 12: 4413. Published online 2021 Jul 20. doi: 10.1038/s41467-021-24703-7

PMCID:: PMC8292527

Abstract Article PDF–6.5M

Select item 450556712.

Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement

Sarah N. Fontaine, Jennifer N. Rauch, Bryce A. Nordhues, Victoria A. Assimon, Andrew R. Stothert, Umesh K. Jinwal, Jonathan J. Sabbagh, Lyra Chang, Stanley M. Stevens, Jr., Erik R. P. Zuiderweg, Jason E. Gestwicki, Chad A. Dickey

J Biol Chem. 2015 May 22; 290(21): 13115–13127. Published online 2015 Apr 11. doi: 10.1074/jbc.M115.637595

PMCID:: PMC4505567

Abstract Article PDF–3.2M

Select item 745748413.

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target

Kumar Saurabh, Parag P. Shah, Mark A. Doll, Leah J. Siskind, Levi J. Beverly

BMC Cancer. 2020; 20: 824. Published online 2020 Aug 31. doi: 10.1186/s12885-020-07322-1

PMCID:: PMC7457484

Abstract Article PDF–3.1M

Select item 343392514.

Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking

Dale S. Haines, J. Eugene Lee, Stephen L. Beauparlant, Dane B. Kyle, Willem den Besten, Michael J. Sweredoski, Robert L. J. Graham, Sonja Hess, Raymond J. Deshaies

Mol Cell Proteomics. 2012 Jun; 11(6): M111.016444. Published online 2012 Feb 14. doi: 10.1074/mcp.M111.016444

PMCID:: PMC3433925

Abstract Article PDF–939K

Select item 692724315.

Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif

Thi Hai Yen Tran, Dae-Wook Yang, Minchul Kim, Da-Hye Lee, Marta Gai, Ferdinando Di Cunto, Kwang-Wook Choi, Dae-Sik Lim

J Mol Cell Biol. 2019 Nov; 11(11): 1006–1017. Published online 2019 Mar 13. doi: 10.1093/jmcb/mjz013

PMCID:: PMC6927243

Abstract Article PDF–1.5M

Select item 630576616.

A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx

Christine D. Landsberg, Dominik A. Megger, Dominik Hotter, Meike U. Rückborn, Mareike Eilbrecht, Jassin Rashidi-Alavijeh, Sebastian Howe, Stefan Heinrichs, Daniel Sauter, Barbara Sitek, Vu Thuy Khanh Le-Trilling, Mirko Trilling

Front Immunol. 2018; 9: 2978. Published online 2018 Dec 19. doi: 10.3389/fimmu.2018.02978

PMCID:: PMC6305766

Abstract Article PDF–4.3M

Select item 596730617.

FAM188B enhances cell survival via interaction with USP7

Eun-Seok Choi, Hanna Lee, Jee Young Sung, Chang-Hun Lee, Hyonchol Jang, Kyung Tae Kim, Yong-Nyun Kim, Hyoung-Pyo Kim, Sung-Ho Goh

Cell Death Dis. 2018 Jun; 9(6): 633. Published online 2018 May 24. doi: 10.1038/s41419-018-0650-6

PMCID:: PMC5967306

Abstract Article PDF–2.8M

Select item 629714118.

The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage

Ryotaro Nishi, Paul W. G. Wijnhoven, Yusuke Kimura, Misaki Matsui, Rebecca Konietzny, Qian Wu, Keisuke Nakamura, Tom L. Blundell, Benedikt M. Kessler

Sci Rep. 2018; 8: 17891. Published online 2018 Dec 17. doi: 10.1038/s41598-018-36235-0

PMCID:: PMC6297141

Abstract Article PDF–2.6M

Select item 445750919.

Ski regulates Hippo and TAZ signaling to suppress breast cancer progression

Juliet Rashidian, Erwan Le Scolan, Xiaodan Ji, Qingwei Zhu, Melinda M. Mulvihill, Daniel Nomura, Kunxin Luo

Sci Signal. Author manuscript; available in PMC 2015 Jun 5.

Published in final edited form as: Sci Signal. 2015 Feb 10; 8(363): ra14. Published online 2015 Feb 10. doi: 10.1126/scisignal.2005735

PMCID:: PMC4457509

Abstract Article PDF–781K

Select item 477633120.

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders

Jingjing Li, Zhihai Ma, Minyi Shi, Ramy H. Malty, Hiroyuki Aoki, Zoran Minic, Sadhna Phanse, Ke Jin, Dennis P. Wall, Zhaolei Zhang, Alexander E. Urban, Joachim Hallmayer, Mohan Babu, Michael Snyder

Cell Syst. Author manuscript; available in PMC 2016 Nov 25.

Published in final edited form as: Cell Syst. 2015 Nov 25; 1(5): 361–374. doi: 10.1016/j.cels.2015.11.002