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Items: 1 to 20 of 38

1.
KLHL22 maintains PD-1 homeostasis and prevents excessive T cell suppression
Xiao Albert Zhou, Jiadong Zhou, Long Zhao, Guihui Yu, Jun Zhan, Chanyi Shi, Ruoshi Yuan, Yan Wang, Changfeng Chen, Wenjia Zhang, Donghao Xu, Yingjiang Ye, Weibin Wang, Zhanlong Shen, Wei Wang, Jiadong Wang
Proc Natl Acad Sci U S A. 2020 Nov 10; 117(45): 28239–28250. Published online 2020 Oct 27. doi: 10.1073/pnas.2004570117
PMCID:
PMC7668036
AbstractArticlePDF–2.8M
2.
CUL3 and protein kinases: Insights from PLK1/KLHL22 interaction
Thibaud Metzger, Charlotte Kleiss, Izabela Sumara
Cell Cycle. 2013 Jul 15; 12(14): 2291–2296. Published online 2013 Jun 24. doi: 10.4161/cc.25369
PMCID:
PMC3755079
AbstractArticlePDF–819K
3.
XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7
Bao‐qin Liu, Rong‐bei Liu, Wen‐ping Li, Xin‐tao Mao, Yi‐ning Li, Tao Huang, Hao‐li Wang, Hao‐tian Chen, Jiang‐yan Zhong, Bing Yang, Ren‐jie Chai, Qian Cao, Jin Jin, Yi‐yuan Li
EMBO Rep. 2023 Jan; 24(1): e55387. Published online 2022 Nov 17. doi: 10.15252/embr.202255387
PMCID:
PMC9827551
AbstractArticlePDF–3.3M
4.
AMPK promotes SPOP-mediated NANOG degradation to regulate prostate cancer cell stemness
Xinbo Wang, Jiali Jin, Fangning Wan, Linlin Zhao, Hongshang Chu, Cong Chen, Guanghong Liao, Jian Liu, Yue Yu, Hongqi Teng, Lan Fang, Cong Jiang, Weijuan Pan, Xin Xie, Jia Li, Xiaolin Lu, Xuejun Jiang, Xin Ge, Dingwei Ye, Ping Wang
Dev Cell. Author manuscript; available in PMC 2020 Sep 29.
Published in final edited form as: Dev Cell. 2019 Feb 11; 48(3): 345–360.e7. Published online 2018 Dec 27. doi: 10.1016/j.devcel.2018.11.033
PMCID:
PMC7523188
AbstractArticlePDF–2.9M
5.
Genome-Wide Association Study of Retinopathy in Individuals without Diabetes
Richard A. Jensen, Xueling Sim, Xiaohui Li, Mary Frances Cotch, M. Kamran Ikram, Elizabeth G. Holliday, Gudny Eiriksdottir, Tamara B. Harris, Fridbert Jonasson, Barbara E. K. Klein, Lenore J. Launer, Albert Vernon Smith, Eric Boerwinkle, Ning Cheung, Alex W. Hewitt, Gerald Liew, Paul Mitchell, Jie Jin Wang, John Attia, Rodney Scott, Nicole L. Glazer, Thomas Lumley, Barbara McKnight, Bruce M. Psaty, Kent Taylor, Albert Hofman, Paulus T. V. M. de Jong, Fernando Rivadeneira, Andre G. Uitterlinden, Wan-Ting Tay, Yik Ying Teo, Mark Seielstad, Jianjun Liu, Ching-Yu Cheng, Seang-Mei Saw, Tin Aung, Santhi K. Ganesh, Christopher J. O'Donnell, Mike A. Nalls, Kerri L. Wiggins, Jane Z. Kuo, The Blue Mountains Eye Study GWAS team, CKDGen Consortium, Cornelia M. van Duijn, Vilmundur Gudnason, Ronald Klein, David S. Siscovick, Jerome I. Rotter, E. Shong Tai, Johannes Vingerling, Tien Y. Wong
PLoS One. 2013; 8(2): e54232. Published online 2013 Feb 5. doi: 10.1371/journal.pone.0054232
PMCID:
PMC3564946
AbstractArticlePDF–724K
6.
Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection
Lorenza P. Ferretti, Sarah-Felicitas Himmels, Anika Trenner, Christina Walker, Christine von Aesch, Aline Eggenschwiler, Olga Murina, Radoslav I. Enchev, Matthias Peter, Raimundo Freire, Antonio Porro, Alessandro A. Sartori
Nat Commun. 2016; 7: 12628. Published online 2016 Aug 26. doi: 10.1038/ncomms12628
PMCID:
PMC5007465
AbstractArticlePDF–3.1M
7.
Ubiquitination-dependent localization of Polo-like kinase 1 in mitosis
Jochen Beck, Sarah Maerki, Markus Posch, Thibaud Metzger, Avinash Persaud, Hartmut Scheel, Kay Hofmann, Daniela Rotin, Patrick Pedrioli, Jason R. Swedlow, Matthias Peter, Izabela Sumara
Nat Cell Biol. Author manuscript; available in PMC 2020 Oct 12.
Published in final edited form as: Nat Cell Biol. 2013 Apr 1; 15(4): 430–9. Published online 2013 Mar 3. doi: 10.1038/ncb2695
PMCID:
PMC7116173
AbstractArticlePDF–2.3M
8.
The Cul3–KLHL21 E3 ubiquitin ligase targets Aurora B to midzone microtubules in anaphase and is required for cytokinesis
Sarah Maerki, Michael H. Olma, Titu Staubli, Patrick Steigemann, Daniel W. Gerlich, Manfredo Quadroni, Izabela Sumara, Matthias Peter
J Cell Biol. 2009 Dec 14; 187(6): 791–800. doi: 10.1083/jcb.200906117
PMCID:
PMC2806313
AbstractArticlePDF–5.9M
9.
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development
Xiangxing Kong, Xin Shu, Jiachuan Wang, Dandan Liu, Yingchun Ni, Weiqi Zhao, Lebo Wang, Zhihua Gao, Jiadong Chen, Bing Yang, Xing Guo, Zhiping Wang
Development. 2022 Dec 15; 149(24): dev201286. Published online 2022 Dec 20. doi: 10.1242/dev.201286
PMCID:
PMC9845739
AbstractArticle
10.
Update on the Kelch-like (KLHL) gene family
Bajinder S Dhanoa, Tiziana Cogliati, Akhila G Satish, Elspeth A Bruford, James S Friedman
Hum Genomics. 2013; 7(1): 13. Published online 2013 May 15. doi: 10.1186/1479-7364-7-13
PMCID:
PMC3658946
AbstractArticlePDF–1.3M
11.
A Novel CUL3 Variant causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase activity
Harish E. Chatrathi, Jason C. Collins, Lynne A. Wolfe, Thomas C. Markello, David R. Adams, William A. Gahl, Achim Werner, Prashant Sharma
Hypertension. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Hypertension. 2022 Jan; 79(1): 60–75. Published online 2021 Dec 2. doi: 10.1161/HYPERTENSIONAHA.121.17624
PMCID:
PMC8667186
AbstractArticlePDF–1.6M
12.
An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases
Michael Hans Olma, Marcia Roy, Thierry Le Bihan, Izabela Sumara, Sarah Maerki, Brett Larsen, Manfredo Quadroni, Matthias Peter, Mike Tyers, Lionel Pintard
J Cell Sci. 2009 Apr 1; 122(7): 1035–1044. Published online 2009 Mar 18. doi: 10.1242/jcs.043539
PMCID:
PMC2720933
AbstractArticle
13.
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover
Gabriela Alexandru, Johannes Graumann, Geoffrey T. Smith, Natalie J. Kolawa, Ruihua Fang, Raymond J. Deshaies
Cell. Author manuscript; available in PMC 2009 Mar 5.
Published in final edited form as: Cell. 2008 Sep 5; 134(5): 804–816. doi: 10.1016/j.cell.2008.06.048
PMCID:
PMC2614663
AbstractArticlePDF–3.7M
14.
Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
Daniel C. Scott, David Y. Rhee, David M. Duda, Ian R. Kelsall, Jennifer L. Olszewski, Joao A. Paulo, Annemieke de Jong, Huib Ovaa, Arno F. Alpi, J. Wade Harper, Brenda A. Schulman
Cell. Author manuscript; available in PMC 2017 Aug 25.
Published in final edited form as: Cell. 2016 Aug 25; 166(5): 1198–1214.e24. doi: 10.1016/j.cell.2016.07.027
PMCID:
PMC5091668
AbstractArticlePDF–4.2M
15.
Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors
Ya-Juan Wang, Xiao-Jing Di, Ting-Wei Mu
J Biol Chem. 2022 Oct; 298(10): 102423. Published online 2022 Aug 27. doi: 10.1016/j.jbc.2022.102423
PMCID:
PMC9493394
AbstractArticlePDF–2.6M
16.
A genome annotation-driven approach to cloning the human ORFeome
John E Collins, Charmain L Wright, Carol A Edwards, Matthew P Davis, James A Grinham, Charlotte G Cole, Melanie E Goward, Begoña Aguado, Meera Mallya, Younes Mokrab, Elizabeth J Huckle, David M Beare, Ian Dunham
Genome Biol. 2004; 5(10): R84. Published online 2004 Sep 30. doi: 10.1186/gb-2004-5-10-r84
PMCID:
PMC545604
AbstractArticlePDF–762K
17.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
Mikko Taipale, George Tucker, Jian Peng, Irina Krykbaeva, Zhen-Yuan Lin, Brett Larsen, Hyungwon Choi, Bonnie Berger, Anne-Claude Gingras, Susan Lindquist
Cell. Author manuscript; available in PMC 2015 Jul 17.
Published in final edited form as: Cell. 2014 Jul 17; 158(2): 434–448. doi: 10.1016/j.cell.2014.05.039
PMCID:
PMC4104544
AbstractArticlePDF–3.2M
18.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M
19.
FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane
Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri
Structure. Author manuscript; available in PMC 2020 Jun 4.
Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022
PMCID:
PMC6551266
AbstractArticlePDF–3.4M
20.
CHK2–BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly
Norman Ertych, Ailine Stolz, Oliver Valerius, Gerhard H. Braus, Holger Bastians
Proc Natl Acad Sci U S A. 2016 Feb 16; 113(7): 1817–1822. Published online 2016 Feb 1. doi: 10.1073/pnas.1525129113
PMCID:
PMC4763769
AbstractArticlePDF–1.3M

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