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Select item 111336251.

A potential defensive role of TIM-3 on T lymphocytes in the inflammatory involvement of diabetic kidney disease

Xiao-Jun Chen, Runyan Tang, Jie Zha, Li Zeng, Linshan Zhou, Zhiwen Liu, Danyi Yang, Mengru Zeng, Xuejing Zhu, Anqun Chen, Hong Liu, Huihui Chen, Guochun Chen

Front Immunol. 2024; 15: 1365226. Published online 2024 May 15. doi: 10.3389/fimmu.2024.1365226

PMCID:: PMC11133625

Abstract Article PDF–18M

Select item 110307732.

Genetic variations and haplotypes in TIM-3 gene and the risk of gastric cancer

Bangwei Cao, Linzhong Zhu, Shengtao Zhu, Danping Li, Chuanzhen Zhang, Changqing Xu, Shutian Zhang

Cancer Immunol Immunother. 2010 Dec; 59(12): 1851–1857. Published online 2010 Sep 2. doi: 10.1007/s00262-010-0910-5

PMCID:: PMC11030773

Abstract Article PDF–218K

Select item 109917023.

The role of TIM-3 in sepsis: a promising target for immunotherapy?

Changli Wang, Jinhai Liu, Qi Wu, Zhi Wang, Baoji Hu, Lulong Bo

Front Immunol. 2024; 15: 1328667. Published online 2024 Mar 21. doi: 10.3389/fimmu.2024.1328667

PMCID:: PMC10991702

Abstract Article PDF–1.2M

Select item 108625664.

The balance between CD4+ T helper 17 and T-cell immunoglobulin and mucin domain 3 is involved in the pathogenesis and development of atrial fibrillation

Wenjing Dai, Jun Zhang, Yang Wang, Jingqun Zhou, Qiuting Dai, Jianfeng Lv

Afr Health Sci. 2023 Sep; 23(3): 607–615. doi: 10.4314/ahs.v23i3.71

PMCID:: PMC10862566

Abstract Article PDF–322K

Select item 107015315.

Case Report: HAVCR2 mutation-associated Hemophagocytic lymphohistiocytosis

Deli Song, Jingshi Wang, Jia Zhang, Junxia Hu, Chaofan Wu, Zhao Wang

Front Immunol. 2023; 14: 1271324. Published online 2023 Nov 23. doi: 10.3389/fimmu.2023.1271324

PMCID:: PMC10701531

Abstract Article PDF–1.2M

Select item 105767096.

TIM-3 as a promising target for cancer immunotherapy in a wide range of tumors

Natalia Sauer, Natalia Janicka, Wojciech Szlasa, Bartłomiej Skinderowicz, Katarzyna Kołodzińska, Wioletta Dwernicka, Małgorzata Oślizło, Julita Kulbacka, Vitalij Novickij, Katarzyna Karłowicz-Bodalska

Cancer Immunol Immunother. 2023 Nov; 72(11): 3405–3425. Published online 2023 Aug 11. doi: 10.1007/s00262-023-03516-1

PMCID:: PMC10576709

Abstract Article PDF–1.5M

Select item 105431637.

Germline HAVCR2 mutations and their relation to the clinical spectrum of subcutaneous panniculitis-like T-cell lymphoma and hemophagocytic lymphohistiocytosis: results from a multicenter study and meta-analysis

Chatphatai Moonla, Chantana Polprasert, Patcharee Komvilaisak, Thanawat Rattanathammethee, Sunisa Kongkiatkamon, Kitsada Wudhikarn, Sirorat Kobbuaklee, Pitchayut Boonyabaramee, Nuanrat Tangcheewinsirikul, Samart Pakakasama, Piya Rujkijyanont, Chane Choed-Amphai, Kamon Phuakpet, Saranya Pongudom, Udomsak Bunworasate, Narittee Sukswai, Darintr Sosothikul, Ponlapat Rojnuckarin

Haematologica. 2023 Oct 1; 108(10): 2743–2752. Published online 2023 Apr 13. doi: 10.3324/haematol.2022.282419

PMCID:: PMC10543163

Abstract Article PDF–1.5M

Select item 101968038.

TIM-3 signaling hijacks the canonical Wnt/β-catenin pathway to maintain cancer stemness in acute myeloid leukemia

Teppei Sakoda, Yoshikane Kikushige, Toshihiro Miyamoto, Hidetoshi Irifune, Takuya Harada, Kiwamu Hatakeyama, Yuya Kunisaki, Koji Kato, Koichi Akashi

Blood Adv. 2023 May 23; 7(10): 2053–2065. Published online 2023 Feb 8. doi: 10.1182/bloodadvances.2022008405

PMCID:: PMC10196803

Abstract Article PDF–1.9M

Select item 101343679.

Upregulation of Tim‐3 is associated with poor prognosis in acute myeloid leukemia

Zhengwei Wu, Jiawang Ou, Nannan Liu, Zhixiang Wang, Junjie Chen, Zihong Cai, Xiaoli Liu, Xiao Yu, Min Dai, Hongsheng Zhou

Cancer Med. 2023 Apr; 12(7): 8956–8969. Published online 2022 Dec 21. doi: 10.1002/cam4.5549

PMCID:: PMC10134367

Abstract Article PDF–11M

Select item 997425810.

Characterization of TIM-3 Expression and Its Correlation with TNF-α and IFN-γ in Patients with Surgically Resected Lung Adenocarcinoma

Jian Tan, Piao Shen, Xingping Yang, Weijie Cai, Hongying Liao

Dis Markers. 2023; 2023: 2352945. Published online 2023 Feb 21. doi: 10.1155/2023/2352945

PMCID:: PMC9974258

Abstract Article PDF–912K

Select item 974186311.

The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse

Shunsuke Kataoka, Priyanka Manandhar, Judong Lee, Creg J. Workman, Hridesh Banerjee, Andrea L. Szymczak-Workman, Michael Kvorjak, Jason Lohmueller, Lawrence P. Kane

Sci Signal. Author manuscript; available in PMC 2022 Dec 11.

Published in final edited form as: Sci Signal. 2021 Jun 15; 14(687): eaba0717. Published online 2021 Jun 15. doi: 10.1126/scisignal.aba0717

PMCID:: PMC9741863

Abstract Article PDF–1.1M

Select item 969375912.

Cutting edges and therapeutic opportunities on tumor-associated macrophages in lung cancer

Qin Hu, Gujie Wu, Runtian Wang, Huiyun Ma, Zhouwei Zhang, Qun Xue

Front Immunol. 2022; 13: 1007812. Published online 2022 Nov 2. doi: 10.3389/fimmu.2022.1007812

PMCID:: PMC9693759

Abstract Article PDF–981K

Select item 947215613.

Unveiling the tumor immune microenvironment of organ-specific melanoma metastatic sites

Jordan W Conway, Robert V Rawson, Serigne Lo, Tasnia Ahmed, Ismael A Vergara, Tuba N Gide, Grace Heloise Attrill, Matteo S Carlino, Robyn P M Saw, John F Thompson, Andrew J Spillane, Kerwin F Shannon, Brindha Shivalingam, Alexander Maxwell Menzies, James S Wilmott, Georgina V Long, Richard A Scolyer, Ines Pires da Silva

J Immunother Cancer. 2022; 10(9): e004884. Published online 2022 Sep 12. doi: 10.1136/jitc-2022-004884

PMCID:: PMC9472156

Abstract Article PDF–5.9M

Select item 905758714.

Tim-3 mediates T cell trogocytosis to limit antitumor immunity

Ornella Pagliano, Robert M. Morrison, Joe-Marc Chauvin, Hridesh Banerjee, Diwakar Davar, Quanquan Ding, Tokiyoshi Tanegashima, Wentao Gao, Saranya R. Chakka, Richelle DeBlasio, Ava Lowin, Kevin Kara, Mignane Ka, Bochra Zidi, Rada Amin, Itay Raphael, Shuowen Zhang, Simon C. Watkins, Cindy Sander, John M. Kirkwood, Marcus Bosenberg, Ana C. Anderson, Vijay K. Kuchroo, Lawrence P. Kane, Alan J. Korman, Arvind Rajpal, Sean M. West, Minhua Han, Christine Bee, Xiaodi Deng, Xiao Min Schebye, Pavel Strop, Hassane M. Zarour

J Clin Invest. 2022 May 2; 132(9): e152864. Published online 2022 May 2. doi: 10.1172/JCI152864

PMCID:: PMC9057587

Abstract Article PDF–2.5M

Select item 901866415.

Tim-3 Expression Causes NK Cell Dysfunction in Type 2 Diabetes Patients

Hui Wang, Kangli Cao, Siyu Liu, Yuanhong Xu, Ling Tang

Front Immunol. 2022; 13: 852436. Published online 2022 Apr 5. doi: 10.3389/fimmu.2022.852436

PMCID:: PMC9018664

Abstract Article PDF–6.1M

Select item 898336316.

TIM-3基因在上皮性卵巢癌中高表达并促进癌细胞的增殖和迁移

霍叶琳, 王月, 安娜, 杜雪

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Feb 20; 42(2): 190–200. Chinese. doi: 10.12122/j.issn.1673-4254.2022.02.04

PMCID:: PMC8983363

Abstract Article PDF–2.6M

Select item 894561617.

Genetic profiles of subcutaneous panniculitis-like T-cell lymphoma and clinicopathological impact of HAVCR2 mutations

Jiwon Koh, Insoon Jang, Seungchan Mun, Cheol Lee, Hee Jeong Cha, Young Ha Oh, Jin-Man Kim, Jae Ho Han, Jin Ho Paik, Junhun Cho, Young Hyeh Ko, Chan-Sik Park, Heounjeong Go, Jooryung Huh, Kwangsoo Kim, Yoon Kyung Jeon

Blood Adv. 2021 Oct 26; 5(20): 3919–3930. Published online 2021 Oct 14. doi: 10.1182/bloodadvances.2021004562

Correction in:: Blood Adv. 2022 Jun 28; 6(12): 3659–3660.

PMCID:: PMC8945616

Abstract Article PDF–2.5M

Select item 888909918.

Increased Expression of Tim-3 Is Associated With Depletion of NKT Cells In SARS-CoV-2 Infection

Jingzhi Yang, Teding Chang, Liangsheng Tang, Hai Deng, Deng Chen, Jialiu Luo, Han Wu, TingXuan Tang, Cong Zhang, Zhenwen Li, Liming Dong, Xiang-Ping Yang, Zhao-Hui Tang

Front Immunol. 2022; 13: 796682. Published online 2022 Feb 16. doi: 10.3389/fimmu.2022.796682