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Select item 12870801.

Localization of a Recessive Gene for North American Indian Childhood Cirrhosis to Chromosome Region 16q22—and Identification of a Shared Haplotype

Christine Bétard, Andrée Rasquin-Weber, Carl Brewer, Eric Drouin, Suzanne Clark, Andrei Verner, Corinne Darmond-Zwaig, Julie Fortin, Jocelyne Mercier, Pierre Chagnon, T. Mary Fujiwara, Kenneth Morgan, Andrea Richter, Thomas J. Hudson, Grant A. Mitchell

Am J Hum Genet. 2000 Jul; 67(1): 222–228. Published online 2000 May 11. doi: 10.1086/302993

PMCID:: PMC1287080

Abstract Article PDF–347K

Select item 34209232.

NOL11, Implicated in the Pathogenesis of North American Indian Childhood Cirrhosis, Is Required for Pre-rRNA Transcription and Processing

Emily F. Freed, José-Luis Prieto, Kathleen L. McCann, Brian McStay, Susan J. Baserga

PLoS Genet. 2012 Aug; 8(8): e1002892. Published online 2012 Aug 16. doi: 10.1371/journal.pgen.1002892

PMCID:: PMC3420923

Abstract Article PDF–2.3M

Select item 29197053.

The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis

Emily F. Freed, Susan J. Baserga

Nucleic Acids Res. 2010 Aug; 38(14): 4798–4806. Published online 2010 Apr 12. doi: 10.1093/nar/gkq185

PMCID:: PMC2919705

Abstract Article PDF–3.8M

Select item 19488594.

Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells

José-Luis Prieto, Brian McStay

Genes Dev. 2007 Aug 15; 21(16): 2041–2054. doi: 10.1101/gad.436707

PMCID:: PMC1948859

Abstract Article PDF–881K

Select item 3785905.

A Missense Mutation (R565W) in Cirhin (FLJ14728) in North American Indian Childhood Cirrhosis

Pierre Chagnon, Jacques Michaud, Grant Mitchell, Jocelyne Mercier, Jean-François Marion, Eric Drouin, Andrée Rasquin-Weber, Thomas J. Hudson, Andrea Richter

Am J Hum Genet. 2002 Dec; 71(6): 1443–1449. Published online 2002 Nov 4. doi: 10.1086/344580

PMCID:: PMC378590

Abstract Article PDF–558K

Select item 29822576.

The Protein Composition of Mitotic Chromosomes Determined Using Multiclassifier Combinatorial Proteomics

Shinya Ohta, Jimi-Carlo Bukowski-Wills, Luis Sanchez-Pulido, Flavia de Lima Alves, Laura Wood, Zhuo A. Chen, Melpi Platani, Lutz Fischer, Damien F. Hudson, Chris P. Ponting, Tatsuo Fukagawa, William C. Earnshaw, Juri Rappsilber

Cell. 2010 Sep 3; 142(5): 810–821. doi: 10.1016/j.cell.2010.07.047

PMCID:: PMC2982257

Abstract Article

Select item 87444647.

Nucleolar maturation of the human small subunit processome

Sameer Singh, Arnaud Vanden Broeck, Linamarie Miller, Malik Chaker-Margot, Sebastian Klinge

Science. Author manuscript; available in PMC 2022 Sep 10.

Published in final edited form as: Science. 2021 Sep 10; 373(6560): eabj5338. Published online 2021 Sep 10. doi: 10.1126/science.abj5338

PMCID:: PMC8744464

Abstract Article PDF–3.6M

Select item 1336178.

Functional Proteomic Analysis of Human Nucleolus

Alexander Scherl, Yohann Couté, Catherine Déon, Aleth Callé, Karine Kindbeiter, Jean-Charles Sanchez, Anna Greco, Denis Hochstrasser, Jean-Jacques Diaz

Mol Biol Cell. 2002 Nov; 13(11): 4100–4109. doi: 10.1091/mbc.E02-05-0271

PMCID:: PMC133617

Abstract Article PDF–369K

Select item 41979479.

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage

Sarah J. Hill, Thomas Rolland, Guillaume Adelmant, Xianfang Xia, Matthew S. Owen, Amélie Dricot, Travis I. Zack, Nidhi Sahni, Yves Jacob, Tong Hao, Kristine M. McKinney, Allison P. Clark, Deepak Reyon, Shengdar Q. Tsai, J. Keith Joung, Rameen Beroukhim, Jarrod A. Marto, Marc Vidal, Suzanne Gaudet, David E. Hill, David M. Livingston

Genes Dev. 2014 Sep 1; 28(17): 1957–1975. doi: 10.1101/gad.241620.114

PMCID:: PMC4197947

Abstract Article PDF–2.4M

Select item 117742710.

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways

Chen Zhao, Carilee Denison, Jon M. Huibregtse, Steven Gygi, Robert M. Krug

Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29): 10200–10205. Published online 2005 Jul 11. doi: 10.1073/pnas.0504754102

PMCID:: PMC1177427

Abstract Article PDF–470K

Select item 637966911.

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex

Danton Ivanochko, Levon Halabelian, Elizabeth Henderson, Pavel Savitsky, Harshika Jain, Edyta Marcon, Shili Duan, Ashley Hutchinson, Alma Seitova, Dalia Barsyte-Lovejoy, Panagis Filippakopoulos, Jack Greenblatt, Evelyne Lima-Fernandes, Cheryl H Arrowsmith

Nucleic Acids Res. 2019 Feb 20; 47(3): 1225–1238. Published online 2018 Nov 20. doi: 10.1093/nar/gky1192

PMCID:: PMC6379669

Abstract Article PDF–7.5M

Select item 631799412.

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response

Lei-Lei Chen, Huai-Peng Lin, Wen-Jie Zhou, Chen-Xi He, Zhi-Yong Zhang, Zhou-Li Cheng, Jun-Bin Song, Peng Liu, Xin-Yu Chen, Yu-Kun Xia, Xiu-Fei Chen, Ren-Qiang Sun, Jing-Ye Zhang, Yi-Ping Sun, Lei Song, Bing-Jie Liu, Rui-Kai Du, Chen Ding, Fei Lan, Sheng-Lin Huang, Feng Zhou, Suling Liu, Yue Xiong, Dan Ye, Kun-Liang Guan

Cell Rep. Author manuscript; available in PMC 2019 Jan 3.

Published in final edited form as: Cell Rep. 2018 Nov 6; 25(6): 1485–1500.e4. doi: 10.1016/j.celrep.2018.10.028

PMCID:: PMC6317994

Abstract Article PDF–1.4M

Select item 644186813.

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

Boshi Wang, Xiaoli Xu, Zhaojuan Yang, Li Zhang, Yun Liu, Aihui Ma, Guiqin Xu, Ming Tang, Tiantian Jing, Lin Wu, Yongzhong Liu

EBioMedicine. 2019 Mar; 41: 320–332. Published online 2019 Feb 7. doi: 10.1016/j.ebiom.2019.01.058

PMCID:: PMC6441868

Abstract Article PDF–7.0M

Select item 546865014.

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation

Ferdinand M. Huber, Sarah M. Greenblatt, Andrew M. Davenport, Concepcion Martinez, Ye Xu, Ly P. Vu, Stephen D. Nimer, André Hoelz

Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23): 6016–6021. Published online 2017 May 22. doi: 10.1073/pnas.1700328114

PMCID:: PMC5468650

Abstract Article PDF–1.3M

Select item 396431015.

The functional interactome landscape of the human histone deacetylase family

Preeti Joshi, Todd M Greco, Amanda J Guise, Yang Luo, Fang Yu, Alexey I Nesvizhskii, Ileana M Cristea

Mol Syst Biol. 2013; 9: 672. Published online 2013 Jun 11. doi: 10.1038/msb.2013.26

PMCID:: PMC3964310

Abstract Article PDF–5.2M

Select item 584953416.

Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS

Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda

Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.

Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012

PMCID:: PMC5849534

Abstract Article PDF–1.1M

Select item 435865917.

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA

Benjamin A Diner, Tuo Li, Todd M Greco, Marni S Crow, John A Fuesler, Jennifer Wang, Ileana M Cristea

Mol Syst Biol. 2015 Feb; 11(2): 787. Published online 2015 Feb 9. doi: 10.15252/msb.20145808

PMCID:: PMC4358659

Abstract Article PDF–3.6M

Select item 456372018.

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression

Benjamin A. Diner, Krystal K. Lum, Aaron Javitt, Ileana M. Cristea

Mol Cell Proteomics. 2015 Sep; 14(9): 2341–2356. Published online 2015 Feb 18. doi: 10.1074/mcp.M114.047068

PMCID:: PMC4563720

Abstract Article PDF–2.8M

Select item 876007719.

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord

Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6

PMCID:: PMC8760077

Abstract Article PDF–12M

Select item 555356820.

A role for mitochondrial translation in promotion of viability in K-Ras mutant cells

Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge

Cell Rep. Author manuscript; available in PMC 2017 Aug 11.

Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061

PMCID:: PMC5553568

Abstract Article PDF–1.8M

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