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Select item 109200901.

Liprin‐α1 contributes to oncogenic MAPK signaling by counteracting ERK activity

Henna Pehkonen, Artemis Filippou, Juho Väänänen, Iida Lindfors, Mira Vänttinen, Philipp Ianevski, Anne Mäkelä, Pauliina Munne, Juha Klefström, Sanna Toppila‐Salmi, Reidar Grénman, Jaana Hagström, Antti A. Mäkitie, Piia‐Riitta Karhemo, Outi Monni

Mol Oncol. 2024 Mar; 18(3): 662–676. Published online 2024 Jan 24. doi: 10.1002/1878-0261.13593

PMCID:: PMC10920090

Abstract Article PDF–2.1M

Select item 101693762.

High expression of PPFIA1 in human esophageal squamous cell carcinoma correlates with tumor metastasis and poor prognosis

Yongyin Gao, Lizhao Guan, Ran Jia, Wanyi Xiao, Youming Han, Yue Li, Peng Tang, Zhentao Yu, Hongdian Zhang

BMC Cancer. 2023; 23: 417. Published online 2023 May 9. doi: 10.1186/s12885-023-10872-9

PMCID:: PMC10169376

Abstract Article PDF–3.7M

Select item 32662333.

Genome Wide Association Identifies PPFIA1 as a Candidate Gene for Acute Lung Injury Risk Following Major Trauma

Jason D. Christie, Mark M. Wurfel, Rui Feng, Grant E. O'Keefe, Jonathan Bradfield, Lorraine B. Ware, David C. Christiani, Carolyn S. Calfee, Mitchell J. Cohen, Michael Matthay, Nuala J. Meyer, Cecilia Kim, Mingyao Li, Joshua Akey, Kathleen C. Barnes, Jonathan Sevransky, Paul N. Lanken, Addison K. May, Richard Aplenc, James P. Maloney, Hakon Hakonarson, for the Trauma ALI SNP Consortium (TASC) investigators

PLoS One. 2012; 7(1): e28268. Published online 2012 Jan 25. doi: 10.1371/journal.pone.0028268

PMCID:: PMC3266233

Abstract Article PDF–287K

Select item 25291694.

Liprin Phosphorylation Regulates Binding to LAR: Evidence for Liprin Autophosphorylation

Carles Serra-Pagès, Michel Streuli, Quintus G. Medley

Biochemistry. Author manuscript; available in PMC 2008 Sep 4.

Published in final edited form as: Biochemistry. 2005 Dec 6; 44(48): 15715–15724. doi: 10.1021/bi051434f

PMCID:: PMC2529169

Abstract Article PDF–1.1M

Select item 60458825.

Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton

Henna Pehkonen, Mira Lento, Pernilla von Nandelstadh, Artemis Filippou, Reidar Grénman, Kaisa Lehti, Outi Monni

Cell Commun Signal. 2018; 16: 41. Published online 2018 Jul 13. doi: 10.1186/s12964-018-0253-y

PMCID:: PMC6045882

Abstract Article PDF–6.0M

Select item 48309316.

Liprin-α1 is a regulator of vimentin intermediate filament network in the cancer cell adhesion machinery

Henna Pehkonen, Pernilla von Nandelstadh, Piia-Riitta Karhemo, Tatiana Lepikhova, Reidar Grenman, Kaisa Lehti, Outi Monni

Sci Rep. 2016; 6: 24486. Published online 2016 Apr 14. doi: 10.1038/srep24486

PMCID:: PMC4830931

Abstract Article PDF–2.9M

Select item 3984017.

The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions.

C Serra-Pagès, N L Kedersha, L Fazikas, Q Medley, A Debant, M Streuli

EMBO J. 1995 Jun 15; 14(12): 2827–2838. doi: 10.1002/j.1460-2075.1995.tb07282.x

PMCID:: PMC398401

Summary Page Browse PDF–3.1M

Select item 57735248.

Identification of a membrane-less compartment regulating invadosome function and motility

Kristyna Sala, Andrea Raimondi, Diletta Tonoli, Carlo Tacchetti, Ivan de Curtis

Sci Rep. 2018; 8: 1164. Published online 2018 Jan 18. doi: 10.1038/s41598-018-19447-2

PMCID:: PMC5773524

Abstract Article PDF–5.8M

Select item 25699669.

Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1

Jiang-Cheng Shen, Motoko Unoki, Damien Ythier, Alain Duperray, Lyuba Varticovski, Kensuke Kumamoto, Remy Pedeux, Curtis C. Harris

Cancer Res. Author manuscript; available in PMC 2008 Oct 20.

Published in final edited form as: Cancer Res. 2007 Mar; 67(6): 2552–2558. doi: 10.1158/0008-5472.CAN-06-3870

PMCID:: PMC2569966

Abstract Article

Select item 209658910.

Identification of an Intramolecular Interaction Important for the Regulation of GIT1 Functions

Antonio Totaro, Simona Paris, Claudia Asperti, Ivan de Curtis

Mol Biol Cell. 2007 Dec; 18(12): 5124–5138. doi: 10.1091/mbc.E07-06-0550

PMCID:: PMC2096589

Abstract Article PDF–2.2M

Select item 512298011.

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis

Giulia Mana, Fabiana Clapero, Emiliano Panieri, Valentina Panero, Ralph T. Böttcher, Hui-Yuan Tseng, Federico Saltarin, Elena Astanina, Katarzyna I. Wolanska, Mark R. Morgan, Martin J. Humphries, Massimo M. Santoro, Guido Serini, Donatella Valdembri

Nat Commun. 2016; 7: 13546. Published online 2016 Nov 23. doi: 10.1038/ncomms13546

PMCID:: PMC5122980

Abstract Article PDF–6.6M

Select item 350056012.

The Liprin Homology Domain Is Essential for the Homomeric Interaction of SYD-2/Liprin-α Protein in Presynaptic Assembly

Hidenori Taru, Yishi Jin

J Neurosci. 2011 Nov 9; 31(45): 16261–16268. doi: 10.1523/JNEUROSCI.0002-11.2011

PMCID:: PMC3500560

Abstract Article PDF–2.1M

Select item 4046713.

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

R Pulido, C Serra-Pagès, M Tang, M Streuli

Proc Natl Acad Sci U S A. 1995 Dec 5; 92(25): 11686–11690. doi: 10.1073/pnas.92.25.11686

PMCID:: PMC40467

Summary Page Browse PDF–1.3M

Select item 832170114.

CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP

Kanako Nishiyama, Masashi Maekawa, Tomoya Nakagita, Jun Nakayama, Takeshi Kiyoi, Mami Chosei, Akari Murakami, Yoshiaki Kamei, Hiroyuki Takeda, Yasutsugu Takada, Shigeki Higashiyama

Life Sci Alliance. 2021 Sep; 4(9): e202101095. Published online 2021 Jun 29. doi: 10.26508/lsa.202101095

PMCID:: PMC8321701

Abstract Article PDF–4.8M

Select item 674197515.

Interaction between Liprin-α and GIT1 Is Required for AMPA Receptor Targeting

Jaewon Ko, Seho Kim, Juli G. Valtschanoff, Hyewon Shin, Jae-Ran Lee, Morgan Sheng, Richard T. Premont, Richard J. Weinberg, Eunjoon Kim

J Neurosci. 2003 Mar 1; 23(5): 1667–1677. doi: 10.1523/JNEUROSCI.23-05-01667.2003

PMCID:: PMC6741975

Abstract Article PDF–1.3M

Select item 456629116.

Proteomic analysis of HIV-1 Gag interacting partners using proximity-dependent biotinylation

Valerie Le Sage, Alessandro Cinti, Fernando Valiente-Echeverría, Andrew J. Mouland

Virol J. 2015; 12: 138. Published online 2015 Sep 11. doi: 10.1186/s12985-015-0365-6

PMCID:: PMC4566291

Abstract Article PDF–1.3M

Select item 262100417.

A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

Marilyn Goudreault, Lisa M. D’Ambrosio, Michelle J. Kean, Michael J. Mullin, Brett G. Larsen, Amy Sanchez, Sidharth Chaudhry, Ginny I. Chen, Frank Sicheri, Alexey I. Nesvizhskii, Ruedi Aebersold, Brian Raught, Anne-Claude Gingras

Mol Cell Proteomics. 2009 Jan; 8(1): 157–171. doi: 10.1074/mcp.M800266-MCP200

PMCID:: PMC2621004

Abstract Article PDF–641K

Select item 632288618.

RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III–dependent transcription

Fang Wang, Kailiang Zhao, Sixiang Yu, An Xu, Wei Han, Yide Mei

J Biol Chem. 2019 Jan 4; 294(1): 130–141. Published online 2018 Nov 9. doi: 10.1074/jbc.RA118.004524

PMCID:: PMC6322886

Abstract Article PDF–3.0M

Select item 567959719.

Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase

Joan A. Lenihan, Orthis Saha, Paul W. Young

PLoS One. 2017; 12(11): e0187352. Published online 2017 Nov 9. doi: 10.1371/journal.pone.0187352

PMCID:: PMC5679597

Abstract Article PDF–10M

Select item 658469120.

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI

Wen-Feng Hu, Kimiko L. Krieger, Dragana Lagundžin, Xueli Li, Ronald S. Cheung, Toshiyasu Taniguchi, Keith R. Johnson, Tadayoshi Bessho, Alvaro N. A. Monteiro, Nicholas T. Woods

Cell Death Discov. 2019; 5: 105. Published online 2019 Jun 19. doi: 10.1038/s41420-019-0185-3

PMCID:: PMC6584691

Abstract Article PDF–1.6M

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PMC Links for Gene (Select 8500) (87)
PMC
PREDICTED: Homo sapiens PTPRF interacting protein alpha 1 (PPFIA1), transcript v...
PREDICTED: Homo sapiens PTPRF interacting protein alpha 1 (PPFIA1), transcript variant X22, mRNA
gi|2217285213|ref|XM_047427771.1|

Nucleotide
PREDICTED: Homo sapiens PTPRF interacting protein alpha 1 (PPFIA1), transcript v...
PREDICTED: Homo sapiens PTPRF interacting protein alpha 1 (PPFIA1), transcript variant X28, mRNA
gi|2217285224|ref|XM_047427776.1|

Nucleotide
liprin-alpha-1 isoform X21 [Homo sapiens]
liprin-alpha-1 isoform X21 [Homo sapiens]
gi|2462497742|ref|XP_054188474.1|

Protein
liprin-alpha-1 isoform X11 [Homo sapiens]
liprin-alpha-1 isoform X11 [Homo sapiens]
gi|767968916|ref|XP_011543616.1|

Protein

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