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Select item 35570551.

Structure of the Sgt2/Get5 complex provides insights into GET-mediated targeting of tail-anchored membrane proteins

Aline C. Simon, Peter J. Simpson, Rachael M. Goldstone, Ewelina M. Krysztofinska, James W. Murray, Stephen High, Rivka L. Isaacson

Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4): 1327–1332. Published online 2013 Jan 7. doi: 10.1073/pnas.1207518110

PMCID:: PMC3557055

Abstract Article PDF–1.1M

Select item 33187092.

Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex

Justin W. Chartron, David G. VanderVelde, Meera Rao, William M. Clemons, Jr.

J Biol Chem. 2012 Mar 9; 287(11): 8310–8317. Published online 2012 Jan 17. doi: 10.1074/jbc.M111.333252

PMCID:: PMC3318709

Abstract Article PDF–1.5M

Select item 90341883.

Deciphering the molecular organization of GET pathway chaperones through native mass spectrometry

Fabian Giska, Malaiyalam Mariappan, Moitrayee Bhattacharyya, Kallol Gupta

Biophys J. 2022 Apr 5; 121(7): 1289–1298. Published online 2022 Feb 19. doi: 10.1016/j.bpj.2022.02.026

PMCID:: PMC9034188

Abstract Article PDF–1.6M

Select item 47059984.

Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting

Harry B. Gristick, Michael E. Rome, Justin W. Chartron, Meera Rao, Sonja Hess, Shu-ou Shan, William M. Clemons, Jr.

J Biol Chem. 2015 Dec 11; 290(50): 30006–30017. Published online 2015 Oct 7. doi: 10.1074/jbc.M115.677328

PMCID:: PMC4705998

Abstract Article PDF–1.8M

Select item 32816435.

Interaction Surface and Topology of Get3-Get4-Get5 Protein Complex, Involved in Targeting Tail-anchored Proteins to Endoplasmic Reticulum

Yi-Wei Chang, Tai-Wen Lin, Yi-Chuan Li, Yu-Shan Huang, Yuh-Ju Sun, Chwan-Deng Hsiao

J Biol Chem. 2012 Feb 10; 287(7): 4783–4789. Published online 2011 Dec 21. doi: 10.1074/jbc.M111.318329

PMCID:: PMC3281643

Abstract Article PDF–1.0M

Select item 29014636.

Structural characterization of the Get4/Get5 complex and its interaction with Get3

Justin W. Chartron, Christian J. M. Suloway, Ma’ayan Zaslaver, William M. Clemons, Jr.

Proc Natl Acad Sci U S A. 2010 Jul 6; 107(27): 12127–12132. Published online 2010 Jun 16. doi: 10.1073/pnas.1006036107

PMCID:: PMC2901463

Abstract Article PDF–2.0M

Select item 91232867.

Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway

Ákos Farkas, Henning Urlaub, Katherine E. Bohnsack, Blanche Schwappach

J Cell Biol. 2022 Jun 6; 221(6): e202201036. Published online 2022 May 19. doi: 10.1083/jcb.202201036

PMCID:: PMC9123286

Abstract Article PDF–5.8M

Select item 56427128.

A protean clamp guides membrane targeting of tail-anchored proteins

Un Seng Chio, SangYoon Chung, Shimon Weiss, Shu-ou Shan

Proc Natl Acad Sci U S A. 2017 Oct 10; 114(41): E8585–E8594. Published online 2017 Sep 26. doi: 10.1073/pnas.1708731114

PMCID:: PMC5642712

Abstract Article PDF–2.4M

Select item 46671879.

Conserved targeting information in mammalian and fungal peroxisomal tail-anchored proteins

Judith Buentzel, Fabio Vilardi, Amelie Lotz-Havla, Jutta Gärtner, Sven Thoms

Sci Rep. 2015; 5: 17420. Published online 2015 Dec 2. doi: 10.1038/srep17420

PMCID:: PMC4667187

Abstract Article PDF–1.0M

Select item 438689810.

Crystal structure of ATP-bound Get3-Get4-Get5 complex reveals regulation of Get3 by Get4

Harry B. Gristick, Meera Rao, Justin W. Chartron, Michael E. Rome, Shu-ou Shan, William M. Clemons, Jr

Nat Struct Mol Biol. Author manuscript; available in PMC 2015 Apr 6.

Published in final edited form as: Nat Struct Mol Biol. 2014 May; 21(5): 437–442. Published online 2014 Apr 13. doi: 10.1038/nsmb.2813

PMCID:: PMC4386898

Abstract Article PDF–2.1M

Select item 424872711.

Structural and Functional Characterization of Ybr137wp Implicates Its Involvement in the Targeting of Tail-Anchored Proteins to Membranes

Yi-Hung Yeh, Tai-Wen Lin, Yi-Chuan Li, Jung-Yu Tung, Cheng-Yuan Lin, Chwan-Deng Hsiao

Mol Cell Biol. 2014 Dec; 34(24): 4500–4512. doi: 10.1128/MCB.00697-14

PMCID:: PMC4248727

Abstract Article PDF–4.6M

Select item 365483112.

Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal a novel interaction that forms a conserved dynamic interface

Justin W. Chartron, David G. VanderVelde, William M. Clemons, Jr.

Cell Rep. Author manuscript; available in PMC 2013 May 15.

Published in final edited form as: Cell Rep. 2012 Dec 27; 2(6): 10.1016/j.celrep.2012.10.010. Published online 2012 Nov 8. doi: 10.1016/j.celrep.2012.10.010

PMCID:: PMC3654831

Abstract Article PDF–2.9M

Select item 365144113.

Precise timing of ATPase activation drives targeting of tail-anchored proteins

Michael E. Rome, Meera Rao, William M. Clemons, Shu-ou Shan

Proc Natl Acad Sci U S A. 2013 May 7; 110(19): 7666–7671. Published online 2013 Apr 22. doi: 10.1073/pnas.1222054110

PMCID:: PMC3651441

Abstract Article PDF–785K

Select item 353220914.

Nuclear Import of UBL-Domain Protein Mdy2 Is Required for Heat-Induced Stress Response in Saccharomyces cerevisiae

Khalid Arhzaouy, Massoud Ramezani-Rad

PLoS One. 2012; 7(12): e52956. Published online 2012 Dec 28. doi: 10.1371/journal.pone.0052956

PMCID:: PMC3532209

Abstract Article PDF–5.1M

Select item 424627915.

Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway

Michael E. Rome, Un Seng Chio, Meera Rao, Harry Gristick, Shu-ou Shan

Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46): E4929–E4935. Published online 2014 Nov 3. doi: 10.1073/pnas.1411284111

PMCID:: PMC4246279

Abstract Article PDF–1.4M

Select item 360618216.

The Association of BAG6 with SGTA and Tail-Anchored Proteins

Pawel Leznicki, Quentin P. Roebuck, Lydia Wunderley, Anne Clancy, Ewelina M. Krysztofinska, Rivka L. Isaacson, Jim Warwicker, Blanche Schwappach, Stephen High

PLoS One. 2013; 8(3): e59590. Published online 2013 Mar 22. doi: 10.1371/journal.pone.0059590