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Select item 108832451.

Tumour‐associated macrophage‐derived DOCK7‐enriched extracellular vesicles drive tumour metastasis in colorectal cancer via the RAC1/ABCA1 axis

Weiwei Chen, Menghua Zhou, Bingjie Guan, Bowen Xie, Youdong Liu, Jiang He, Jingjing Zhao, Qian Zhao, Dongwang Yan

Clin Transl Med. 2024 Feb; 14(2): e1591. Published online 2024 Feb 22. doi: 10.1002/ctm2.1591

PMCID:: PMC10883245

Article PDF–30M

Select item 81041632.

Characteristic facial features and cortical blindness distinguish the DOCK7‐related epileptic encephalopathy

Edda Haberlandt, Taras Valovka, Tanja Janjic, Thomas Müller, Georgios Blatsios, Daniela Karall, Andreas R. Janecke

Mol Genet Genomic Med. 2021 Mar; 9(3): e1607. Published online 2021 Jan 20. doi: 10.1002/mgg3.1607

PMCID:: PMC8104163

Article PDF–814K

Select item 80346143.

DOCK7 protects against replication stress by promoting RPA stability on chromatin

Ming Gao, Guijie Guo, Jinzhou Huang, Xiaonan Hou, Hyoungjun Ham, Wootae Kim, Fei Zhao, Xinyi Tu, Qin Zhou, Chao Zhang, Qian Zhu, Jiaqi Liu, Yuanliang Yan, Zhijie Xu, Ping Yin, Kuntian Luo, John Weroha, Min Deng, Daniel D Billadeau, Zhenkun Lou

Nucleic Acids Res. 2021 Apr 6; 49(6): 3322–3337. Published online 2021 Mar 11. doi: 10.1093/nar/gkab134

PMCID:: PMC8034614

Article PDF–2.4M

Select item 41214774.

Mutations in DOCK7 in Individuals with Epileptic Encephalopathy and Cortical Blindness

Isabelle Perrault, Fadi F. Hamdan, Marlène Rio, José-Mario Capo-Chichi, Nathalie Boddaert, Jean-Claude Décarie, Bruno Maranda, Rima Nabbout, Michel Sylvain, Anne Lortie, Philippe P. Roux, Elsa Rossignol, Xavier Gérard, Giulia Barcia, Patrick Berquin, Arnold Munnich, Guy A. Rouleau, Josseline Kaplan, Jean-Michel Rozet, Jacques L. Michaud

Am J Hum Genet. 2014 Jun 5; 94(6): 891–897. doi: 10.1016/j.ajhg.2014.04.012

PMCID:: PMC4121477

Article PDF–1.3M

Select item 58163845.

DOCK7-ANGPTL3 SNPs and their haplotypes with serum lipid levels and the risk of coronary artery disease and ischemic stroke

Wei-Jun Li, Rui-Xing Yin, Xiao-Li Cao, Wu-Xian Chen, Feng Huang, Jin-Zhen Wu

Lipids Health Dis. 2018; 17: 30. Published online 2018 Feb 17. doi: 10.1186/s12944-018-0677-9

PMCID:: PMC5816384

Article PDF–951K

Select item 39508766.

Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation

D W Murray, S Didier, A Chan, V Paulino, L Van Aelst, R Ruggieri, N L Tran, A T Byrne, M Symons

Br J Cancer. 2014 Mar 4; 110(5): 1307–1315. Published online 2014 Feb 11. doi: 10.1038/bjc.2014.39

PMCID:: PMC3950876

Article PDF–976K

Select item 47275557.

Association of the variants and haplotypes in the DOCK7, PCSK9 and GALNT2 genes and the risk of hyperlipidaemia

Tao Guo, Rui‐Xing Yin, Wei‐Xiong Lin, Wei Wang, Feng Huang, Shang‐Ling Pan

J Cell Mol Med. 2016 Feb; 20(2): 243–265. Published online 2015 Oct 23. doi: 10.1111/jcmm.12713

PMCID:: PMC4727555

Article PDF–166K

Select item 47054738.

Association between the DOCK7, PCSK9 and GALNT2 Gene Polymorphisms and Serum Lipid levels

Tao Guo, Rui-Xing Yin, Feng Huang, Li-Mei Yao, Wei-Xiong Lin, Shang-Ling Pan

Sci Rep. 2016; 6: 19079. Published online 2016 Jan 8. doi: 10.1038/srep19079

PMCID:: PMC4705473

Article PDF–1.5M

Select item 37439399.

Altered thermogenesis and impaired bone remodeling in Misty mice

Katherine J Motyl, Kathleen A Bishop, Victoria E DeMambro, Sheila A Bornstein, Phuong Le, Masanobu Kawai, Sutada Lotinun, Mark C Horowitz, Roland Baron, Mary L Bouxsein, Clifford J Rosen

J Bone Miner Res. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Bone Miner Res. 2013 Sep; 28(9): 1885–1897. doi: 10.1002/jbmr.1943

PMCID:: PMC3743939

Article PDF–1.7M

Select item 375268510.

Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7

Yeyun Zhou, Jared L. Johnson, Richard A. Cerione, Jon W. Erickson

Biochemistry. Author manuscript; available in PMC 2014 Jun 25.

Published in final edited form as: Biochemistry. 2013 Jun 25; 52(25): 4354–4363. Published online 2013 Jun 14. doi: 10.1021/bi301688g

PMCID:: PMC3752685

Article PDF–3.2M

Select item 328173711.

Bone Morphogenetic Protein 4 Promotes Vascular Smooth Muscle Contractility by Activating MicroRNA-21 (miR-21), which Down-regulates Expression of Family of Dedicator of Cytokinesis (DOCK) Proteins

Hara Kang, Brandi N. Davis-Dusenbery, Peter H. Nguyen, Ashish Lal, Judy Lieberman, Linda Van Aelst, Giorgio Lagna, Akiko Hata

J Biol Chem. 2012 Feb 3; 287(6): 3976–3986. Published online 2011 Dec 9. doi: 10.1074/jbc.M111.303156

PMCID:: PMC3281737

Article PDF–2.2M

Select item 587778312.

Nbeal2 interacts with Dock7, Sec16a, and Vac14

Louisa Mayer, Maria Jasztal, Mercedes Pardo, Salvadora Aguera de Haro, Janine Collins, Tadbir K. Bariana, Peter A. Smethurst, Luigi Grassi, Romina Petersen, Paquita Nurden, Rémi Favier, Lu Yu, Stuart Meacham, William J. Astle, Jyoti Choudhary, Wyatt W. Yue, Willem H. Ouwehand, Jose A. Guerrero

Blood. 2018 Mar 1; 131(9): 1000–1011. Prepublished online 2017 Nov 29. doi: 10.1182/blood-2017-08-800359

PMCID:: PMC5877783

Article

Select item 231568013.

ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration

Junji Yamauchi, Yuki Miyamoto, Jonah R. Chan, Akito Tanoue

J Cell Biol. 2008 Apr 21; 181(2): 351–365. doi: 10.1083/jcb.200709033

PMCID:: PMC2315680

Article PDF–4.1M

Select item 387541514.

A Genome Wide Association Study Identifies Common Variants Associated with Lipid Levels in the Chinese Population

Li Zhou, Meian He, Zengnan Mo, Chen Wu, Handong Yang, Dianke Yu, Xiaobo Yang, Xiaomin Zhang, Yiqin Wang, Jielin Sun, Yong Gao, Aihua Tan, Yunfeng He, Haiying Zhang, Xue Qin, Jingwen Zhu, Huaixing Li, Xu Lin, Jiang Zhu, Xinwen Min, Mingjian Lang, Dongfeng Li, Kan Zhai, Jiang Chang, Wen Tan, Jing Yuan, Weihong Chen, Youjie Wang, Sheng Wei, Xiaoping Miao, Feng Wang, Weimin Fang, Yuan Liang, Qifei Deng, Xiayun Dai, Dafeng Lin, Suli Huang, Huan Guo, S. Lilly Zheng, Jianfeng Xu, Dongxin Lin, Frank B. Hu, Tangchun Wu

PLoS One. 2013; 8(12): e82420. Published online 2013 Dec 30. doi: 10.1371/journal.pone.0082420

PMCID:: PMC3875415

Article PDF–786K

Select item 471942815.

Role of Ostm1 Cytosolic Complex with Kinesin 5B in Intracellular Dispersion and Trafficking

Subramanya N. M. Pandruvada, Janie Beauregard, Suzanne Benjannet, Monica Pata, Claude Lazure, Nabil G. Seidah, Jean Vacher

Mol Cell Biol. 2016 Feb 1; 36(3): 507–521. Prepublished online 2015 Nov 23. Published online 2016 Jan 19. doi: 10.1128/MCB.00656-15

PMCID:: PMC4719428

Article PDF–4.0M

Select item 496492816.

Diverse functions of myosin VI elucidated by an isoform-specific a-helix domain

Hans-Peter Wollscheid, Matteo Biancospino, Fahu He, Elisa Magistrati, Erika Molteni, Michela Lupia, Paolo Soffientini, Klemens Rottner, Ugo Cavallaro, Uberto Pozzoli, Marina Mapelli, Kylie J. Walters, Simona Polo

Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Nat Struct Mol Biol. 2016 Apr; 23(4): 300–308. Published online 2016 Mar 7. doi: 10.1038/nsmb.3187

PMCID:: PMC4964928

Article PDF–2.1M

Select item 277739017.

Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis

Daniel I. Chasman, Guillaume Paré, Samia Mora, Jemma C. Hopewell, Gina Peloso, Robert Clarke, L. Adrienne Cupples, Anders Hamsten, Sekar Kathiresan, Anders Mälarstig, José M. Ordovas, Samuli Ripatti, Alex N. Parker, Joseph P. Miletich, Paul M. Ridker

PLoS Genet. 2009 Nov; 5(11): e1000730. Published online 2009 Nov 20. doi: 10.1371/journal.pgen.1000730

PMCID:: PMC2777390

Article PDF–462K

Select item 280546818.

Association of Mitotic Regulation Pathway Polymorphisms with Pancreatic Cancer Risk and Outcome

Fergus J. Couch, Xianshu Wang, William R. Bamlet, Mariza de Andrade, Gloria M. Petersen, Robert R. McWilliams

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Jan; 19(1): 251–257. doi: 10.1158/1055-9965.EPI-09-0629

PMCID:: PMC2805468

Article PDF–306K

Select item 268249319.

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

Sekar Kathiresan, Olle Melander, Candace Guiducci, Aarti Surti, Noël P Burtt, Mark J Rieder, Gregory M Cooper, Charlotta Roos, Benjamin F Voight, Aki S Havulinna, Björn Wahlstrand, Thomas Hedner, Dolores Corella, E Shyong Tai, Jose M Ordovas, Göran Berglund, Erkki Vartiainen, Pekka Jousilahti, Bo Hedblad, Marja-Riitta Taskinen, Christopher Newton-Cheh, Veikko Salomaa, Leena Peltonen, Leif Groop, David M Altshuler, Marju Orho-Melander

Nat Genet. Author manuscript; available in PMC 2009 May 14.

Published in final edited form as: Nat Genet. 2008 Feb; 40(2): 189–197. Published online 2008 Jan 13. doi: 10.1038/ng.75

Correction in:: volume 40 on page 1384

PMCID:: PMC2682493

Article PDF–312K

Select item 268707420.

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

Yurii S Aulchenko, Samuli Ripatti, Ida Lindqvist, Dorret Boomsma, Iris M Heid, Peter P Pramstaller, Brenda W J H Penninx, A Cecile J W Janssens, James F Wilson, Tim Spector, Nicholas G Martin, Nancy L Pedersen, Kirsten Ohm Kyvik, Jaakko Kaprio, Albert Hofman, Nelson B Freimer, Marjo-Riitta Jarvelin, Ulf Gyllensten, Harry Campbell, Igor Rudan, Åsa Johansson, Fabio Marroni, Caroline Hayward, Veronique Vitart, Inger Jonasson, Cristian Pattaro, Alan Wright, Nick Hastie, Irene Pichler, Andrew A Hicks, Mario Falchi, Gonneke Willemsen, Jouke-Jan Hottenga, Eco J C de Geus, Grant W Montgomery, John Whitfield, Patrik Magnusson, Juha Saharinen, Markus Perola, Kaisa Silander, Aaron Isaacs, Eric J G Sijbrands, Andre G Uitterlinden, Jacqueline C M Witteman, Ben A Oostra, Paul Elliott, Aimo Ruokonen, Chiara Sabatti, Christian Gieger, Thomas Meitinger, Florian Kronenberg, Angela Döring, H-Erich Wichmann, Johannes H Smit, Mark I McCarthy, Cornelia M van Duijn, Leena Peltonen, for the ENGAGE Consortium

Nat Genet. Author manuscript; available in PMC 2009 Jul 1.

Published in final edited form as: Nat Genet. 2009 Jan; 41(1): 47–55. Published online 2008 Dec 7. doi: 10.1038/ng.269

PMCID:: PMC2687074

Article PDF–596K

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