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Select item 104974151.

Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge

Eva P. Karasmanis, Janice M. Reimer, Agnieszka A. Kendrick, Kendrick H. V. Nguyen, Jennifer A. Rodriguez, Joey B. Truong, Indrajit Lahiri, Samara L. Reck-Peterson, Andres E. Leschziner

Nat Struct Mol Biol. 2023; 30(9): 1357–1364. Published online 2023 Aug 24. doi: 10.1038/s41594-023-01069-6

PMCID:: PMC10497415

Abstract Article PDF–7.1M

Select item 88244742.

Structural basis for cytoplasmic dynein-1 regulation by Lis1

John P Gillies, Janice M Reimer, Eva P Karasmanis, Indrajit Lahiri, Zaw Min Htet, Andres E Leschziner, Samara L Reck-Peterson

eLife. 2022; 11: e71229. Published online 2022 Jan 7. doi: 10.7554/eLife.71229

PMCID:: PMC8824474

Abstract Article PDF–12M

Select item 43593663.

Lis1 regulates dynein by sterically blocking its mechanochemical cycle

Katerina Toropova, Sirui Zou, Anthony J Roberts, William B Redwine, Brian S Goodman, Samara L Reck-Peterson, Andres E Leschziner

eLife. 2014; 3: e03372. Published online 2014 Nov 7. doi: 10.7554/eLife.03372

PMCID:: PMC4359366

Abstract Article PDF–3.0M

Select item 34384484.

Lis1 Acts as a “Clutch” between the ATPase and Microtubule-Binding Domains of the Dynein Motor

Julie Huang, Anthony J. Roberts, Andres E. Leschziner, Samara L. Reck-Peterson

Cell. 2012 Aug 31; 150(5): 975–986. doi: 10.1016/j.cell.2012.07.022

PMCID:: PMC3438448

Abstract Article PDF–3.7M

Select item 30534425.

Quantitative Analysis of Pac1/LIS1-mediated Dynein Targeting: Implications for Regulation of Dynein Activity in Budding Yeast

Steven M. Markus, Karen M. Plevock, Bryan J. St. Germain, Jesse J. Punch, Christopher W. Meaden, Wei-Lih Lee

Cytoskeleton (Hoboken) Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Cytoskeleton (Hoboken). 2011 Mar; 68(3): 157–174. Published online 2011 Feb 3. doi: 10.1002/cm.20502

PMCID:: PMC3053442

Abstract Article PDF–2.1M

Select item 85038456.

Substrate ubiquitination retains misfolded membrane proteins in the endoplasmic reticulum for degradation

Zhihao Sun, Christopher J. Guerriero, Jeffrey L. Brodsky

Cell Rep. Author manuscript; available in PMC 2021 Oct 11.

Published in final edited form as: Cell Rep. 2021 Sep 21; 36(12): 109717. doi: 10.1016/j.celrep.2021.109717

PMCID:: PMC8503845

Abstract Article PDF–2.2M

Select item 56258417.

Lis1 has two opposing modes of regulating cytoplasmic dynein

Morgan E. DeSantis, Michael A. Cianfrocco, Zaw Min Htet, Phuoc Tien Tran, Samara L. Reck-Peterson, Andres E. Leschziner

Cell. Author manuscript; available in PMC 2018 Sep 7.

Published in final edited form as: Cell. 2017 Sep 7; 170(6): 1197–1208.e12. doi: 10.1016/j.cell.2017.08.037

PMCID:: PMC5625841

Abstract Article PDF–3.8M

Select item 105902758.

Microtubule binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport

William D. Ton, Yue Wang, Pengxin Chai, Cisloynny Beauchamp-Perez, Nicholas T. Flint, Lindsay G. Lammers, Hao Xiong, Kai Zhang, Steven M. Markus

Nat Struct Mol Biol. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Nat Struct Mol Biol. 2023 Sep; 30(9): 1365–1379. Published online 2023 Jun 15. doi: 10.1038/s41594-023-01010-x

PMCID:: PMC10590275

Abstract Article PDF–8.9M

Select item 46218409.

The dynein cortical anchor Num1 activates dynein motility by relieving Pac1/LIS1-mediated inhibition

Lindsay G. Lammers, Steven M. Markus

J Cell Biol. 2015 Oct 26; 211(2): 309–322. doi: 10.1083/jcb.201506119

PMCID:: PMC4621840

Abstract Article PDF–8.6M

Select item 309924410.

Regulated Offloading of Cytoplasmic Dynein from Microtubule Plus Ends to the Cortex

Steven M. Markus, Wei-Lih Lee

Dev Cell. Author manuscript; available in PMC 2012 May 17.

Published in final edited form as: Dev Cell. 2011 May 17; 20(5): 639–651. doi: 10.1016/j.devcel.2011.04.011

PMCID:: PMC3099244

Abstract Article PDF–1.1M

Select item 156943311.

NudEL targets dynein to microtubule ends through LIS1

Jun Li, Wei-Lih Lee, John A. Cooper

Nat Cell Biol. Author manuscript; available in PMC 2006 Sep 15.

Published in final edited form as: Nat Cell Biol. 2005 Jul; 7(7): 686–690. Published online 2005 Jun 19. doi: 10.1038/ncb1273

PMCID:: PMC1569433

Abstract Article PDF–1.0M

Select item 741359312.

Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity

Matthew G. Marzo, Jacqueline M. Griswold, Steven M. Markus

Nat Cell Biol. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Nat Cell Biol. 2020 May; 22(5): 559–569. Published online 2020 Apr 27. doi: 10.1038/s41556-020-0492-1

PMCID:: PMC7413593

Abstract Article PDF–6.0M

Select item 217267213.

The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast

Wei-Lih Lee, Jessica R. Oberle, John A. Cooper

J Cell Biol. 2003 Feb 3; 160(3): 355–364. doi: 10.1083/jcb.200209022

PMCID:: PMC2172672

Abstract Article PDF–4.1M

Select item 8488614.

Bni1p Regulates Microtubule-Dependent Nuclear Migration through the Actin Cytoskeleton in Saccharomyces cerevisiae

Takeshi Fujiwara, Kazuma Tanaka, Eiji Inoue, Mitsuhiro Kikyo, Yoshimi Takai

Mol Cell Biol. 1999 Dec; 19(12): 8016–8027. doi: 10.1128/mcb.19.12.8016

PMCID:: PMC84886

Abstract Article PDF–1.2M

Select item 404656415.

Reconstitution of dynein transport to the microtubule plus end by kinesin

Anthony J Roberts, Brian S Goodman, Samara L Reck-Peterson

eLife. 2014; 3: e02641. Published online 2014 Jun 10. doi: 10.7554/eLife.02641

PMCID:: PMC4046564

Abstract Article PDF–2.0M

Select item 267429916.

Motor and Tail Dependent Targeting of Dynein to Microtubule Plus-Ends and the Cell Cortex

Steven M. Markus, Jesse J. Punch, Wei-Lih Lee

Curr Biol. Author manuscript; available in PMC 2010 Feb 10.

Published in final edited form as: Curr Biol. 2009 Feb 10; 19(3): 196–205. Published online 2009 Jan 29. doi: 10.1016/j.cub.2008.12.047

PMCID:: PMC2674299

Abstract Article PDF–1.6M

Select item 351001717.

The yeast homologue of the microtubule-associated protein Lis1 interacts with the sumoylation machinery and a SUMO-targeted ubiquitin ligase

Annabel Alonso, Sonia D'Silva, Maliha Rahman, Pam B. Meluh, Jacob Keeling, Nida Meednu, Harold J. Hoops, Rita K. Miller

Mol Biol Cell. 2012 Dec 1; 23(23): 4552–4566. doi: 10.1091/mbc.E12-03-0195

PMCID:: PMC3510017

Abstract Article PDF–1.8M

Select item 671295318.

The TOG protein Stu2/XMAP215 interacts covalently and noncovalently with SUMO

Matt Greenlee, Annabel Alonso, Maliha Rahman, Nida Meednu, Kayla Davis, Victoria Tabb, River Cook, Rita K. Miller

Cytoskeleton (Hoboken) 2018 Jul; 75(7): 290–306. Published online 2018 Jul 2. doi: 10.1002/cm.21449

PMCID:: PMC6712953

Abstract Article PDF–11M

Select item 236737119.

Dynactin Function in Mitotic Spindle Positioning

Jeffrey K. Moore, Jun Li, John A. Cooper

Traffic. Author manuscript; available in PMC 2008 May 6.

Published in final edited form as: Traffic. 2008 Apr; 9(4): 510–527. Published online 2008 Jan 22. doi: 10.1111/j.1600-0854.2008.00710.x

PMCID:: PMC2367371

Abstract Article PDF–2.3M

Select item 30571220.

Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways.

J R Geiser, E J Schott, T J Kingsbury, N B Cole, L J Totis, G Bhattacharyya, L He, M A Hoyt

Mol Biol Cell. 1997 Jun; 8(6): 1035–1050. doi: 10.1091/mbc.8.6.1035

PMCID:: PMC305712

Summary Page Browse PDF–3.2M

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PMC Links for Gene (Select 854443) (51)
PMC
GPL30515[RGSE] (5)
GEO DataSets
UI-E-EO1-aja-c-04-0-UI.s1 UI-E-EO1 Homo sapiens cDNA clone UI-E-EO1-aja-c-04-0-U...
UI-E-EO1-aja-c-04-0-UI.s1 UI-E-EO1 Homo sapiens cDNA clone UI-E-EO1-aja-c-04-0-UI 3', mRNA sequence
gi|18990088|gnl|dbEST|11261125|gb|B 86.1|

Nucleotide
PREDICTED: Homo sapiens uncharacterized lncRNA (LOC105374254), transcript varian...
PREDICTED: Homo sapiens uncharacterized lncRNA (LOC105374254), transcript variant X2, ncRNA
gi|2217348200|ref|XR_924792.3|

Nucleotide

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