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Select item 80112871.

Incomplete mitophagy in the mevalonate kinase-deficient Saccharomyces cerevisiae and its relation to the MKD-related autoinflammatory disease in humans

Manuella Maria Silva Santos, Damián Gatica, Jaqueline de Azêvedo Silva, Sergio Crovella, Daniel J. Klionsky, Marcos Antonio de Morais, Jr

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1; 1867(4): 166053. Published online 2020 Dec 29. doi: 10.1016/j.bbadis.2020.166053

PMCID:: PMC8011287

Abstract Article PDF–161K

Select item 3906222.

Sterol control of the phosphatidylethanolamine-phosphatidylcholine conversion in the yeast mutant GL7.

S Kawasaki, M Ramgopal, J Chin, K Bloch

Proc Natl Acad Sci U S A. 1985 Sep; 82(17): 5715–5719. doi: 10.1073/pnas.82.17.5715

PMCID:: PMC390622

Summary Page Browse PDF–1.0M

Select item 38964893.

Allosteric Regulation of the Hsp90 Dynamics and Stability by Client Recruiter Cochaperones: Protein Structure Network Modeling

Kristin Blacklock, Gennady M. Verkhivker

PLoS One. 2014; 9(1): e86547. Published online 2014 Jan 20. doi: 10.1371/journal.pone.0086547

PMCID:: PMC3896489

Abstract Article PDF–6.1M

Select item 24352794.

Genetic Interactions of MAF1 Identify a Role for Med20 in Transcriptional Repression of Ribosomal Protein Genes

Ian M. Willis, Gordon Chua, Amy H. Tong, Renee L. Brost, Timothy R. Hughes, Charles Boone, Robyn D. Moir

PLoS Genet. 2008 Jul; 4(7): e1000112. Published online 2008 Jul 4. doi: 10.1371/journal.pgen.1000112

PMCID:: PMC2435279

Abstract Article PDF–439K

Select item 47189225.

Systematic humanization of yeast genes reveals conserved functions and genetic modularity

Aashiq H. Kachroo, Jon M. Laurent, Christopher M. Yellman, Austin G. Meyer, Claus O. Wilke, Edward M. Marcotte

Science. Author manuscript; available in PMC 2016 Jan 20.

Published in final edited form as: Science. 2015 May 22; 348(6237): 921–925. doi: 10.1126/science.aaa0769

PMCID:: PMC4718922

Abstract Article PDF–2.0M

Select item 46496506.

Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants

Akil Hamza, Erik Tammpere, Megan Kofoed, Christelle Keong, Jennifer Chiang, Guri Giaever, Corey Nislow, Philip Hieter

Genetics. 2015 Nov; 201(3): 1263–1274. Published online 2015 Sep 9. doi: 10.1534/genetics.115.181099

PMCID:: PMC4649650

Abstract Article PDF–6.2M

Select item 91699137.

The ubiquitin–proteasome system regulates meiotic chromosome organization

Xiao Yang, Meihui Song, Ying Wang, Taicong Tan, Zhongyu Tian, Binyuan Zhai, Xuan Yang, Yingjin Tan, Yanding Cao, Shaojun Dai, Shunxin Wang, Liangran Zhang

Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17): e2106902119. Published online 2022 Apr 19. doi: 10.1073/pnas.2106902119

PMCID:: PMC9169913

Abstract Article PDF–2.1M

Select item 35332868.

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

Mahadeo A. Sukhai, Swayam Prabha, Rose Hurren, Angela C. Rutledge, Anna Y. Lee, Shrivani Sriskanthadevan, Hong Sun, Xiaoming Wang, Marko Skrtic, Ayesh Seneviratne, Maria Cusimano, Bozhena Jhas, Marcela Gronda, Neil MacLean, Eunice E. Cho, Paul A. Spagnuolo, Sumaiya Sharmeen, Marinella Gebbia, Malene Urbanus, Kolja Eppert, Dilan Dissanayake, Alexia Jonet, Alexandra Dassonville-Klimpt, Xiaoming Li, Alessandro Datti, Pamela S. Ohashi, Jeff Wrana, Ian Rogers, Pascal Sonnet, William Y. Ellis, Seth J. Corey, Connie Eaves, Mark D. Minden, Jean C.Y. Wang, John E. Dick, Corey Nislow, Guri Giaever, Aaron D. Schimmer

J Clin Invest. 2013 Jan 2; 123(1): 315–328. Published online 2012 Dec 3. doi: 10.1172/JCI64180

PMCID:: PMC3533286

Abstract Article PDF–2.1M

Select item 37913129.

A Lipid E-MAP Identifies Ubx2 as a Critical Regulator of Lipid Saturation and Lipid Bilayer Stress

Michal A. Surma, Christian Klose, Debby Peng, Michael Shales, Caroline Mrejen, Adam Stefanko, Hannes Braberg, David E. Gordon, Daniela Vorkel, Christer S. Ejsing, Robert Farese, Jr., Kai Simons, Nevan J. Krogan, Robert Ernst

Mol Cell. Author manuscript; available in PMC 2014 Aug 22.

Published in final edited form as: Mol Cell. 2013 Aug 22; 51(4): 519–530. Published online 2013 Jul 25. doi: 10.1016/j.molcel.2013.06.014

PMCID:: PMC3791312

Abstract Article PDF–1.9M

Select item 520924510.

A network of conserved synthetic lethal interactions for exploration of precision cancer therapy

Rohith Srivas, John Paul Shen, Chih Cheng Yang, Su Ming Sun, Jianfeng Li, Andrew M. Gross, James Jensen, Katherine Licon, Ana Bojorquez-Gomez, Kristin Klepper, Justin Huang, Daniel Pekin, Jia L. Xu, Huwate Yeerna, Vignesh Sivaganesh, Leonie Kollenstart, Haico van Attikum, Pedro Aza-Blanc, Robert W. Sobol, Trey Ideker

Mol Cell. Author manuscript; available in PMC 2017 Aug 4.

Published in final edited form as: Mol Cell. 2016 Aug 4; 63(3): 514–525. Published online 2016 Jul 21. doi: 10.1016/j.molcel.2016.06.022

PMCID:: PMC5209245

Abstract Article PDF–1.6M

Select item 312543911.

An integrated approach to characterize genetic interaction networks in yeast metabolism

Balázs Szappanos, Károly Kovács, Béla Szamecz, Frantisek Honti, Michael Costanzo, Anastasia Baryshnikova, Gabriel Gelius-Dietrich, Martin J. Lercher, Márk Jelasity, Chad L. Myers, Brenda J. Andrews, Charles Boone, Stephen G. Oliver, Csaba Pál, Balázs Papp

Nat Genet. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: Nat Genet. 2011 Jul; 43(7): 656–662. Published online 2011 May 29. doi: 10.1038/ng.846

PMCID:: PMC3125439

Abstract Article PDF–2.5M

Select item 328593312.

La-motif–dependent mRNA association with Slf1 promotes copper detoxification in yeast

Luca Schenk, Dominik M. Meinel, Katja Strässer, André P. Gerber

RNA. 2012 Mar; 18(3): 449–461. doi: 10.1261/rna.028506.111

PMCID:: PMC3285933

Abstract Article PDF–812K

Select item 1029770013.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 356498714.

Saccharomyces cerevisiae Genetics Predicts Candidate Therapeutic Genetic Interactions at the Mammalian Replication Fork

Derek M. van Pel, Peter C. Stirling, Sean W. Minaker, Payal Sipahimalani, Philip Hieter

G3 (Bethesda) 2013 Feb; 3(2): 273–282. Published online 2013 Feb 1. doi: 10.1534/g3.112.004754

PMCID:: PMC3564987

Abstract Article PDF–2.3M

Select item 319815615.

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

Suzanne Hoppins, Sean R. Collins, Ann Cassidy-Stone, Eric Hummel, Rachel M. DeVay, Laura L. Lackner, Benedikt Westermann, Maya Schuldiner, Jonathan S. Weissman, Jodi Nunnari

J Cell Biol. 2011 Oct 17; 195(2): 323–340. doi: 10.1083/jcb.201107053

PMCID:: PMC3198156

Abstract Article PDF–4.1M

Select item 486983516.

One library to make them all: Streamlining yeast library creation by a SWAp-Tag (SWAT) strategy

Ido Yofe, Uri Weill, Matthias Meurer, Silvia Chuartzman, Einat Zalckvar, Omer Goldman, Shifra Ben-Dor, Conny Schütze, Nils Wiedemann, Michael Knop, Anton Khmelinskii, Maya Schuldiner

Nat Methods. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Nat Methods. 2016 Apr; 13(4): 371–378. Published online 2016 Feb 29. doi: 10.1038/nmeth.3795

PMCID:: PMC4869835

Abstract Article PDF–2.7M

Select item 355349717.

The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis

Felix Willmund, Marta del Alamo, Sebastian Pechmann, Taotao Chen, Veronique Albanese, Eric B. Dammer, Junmin Peng, Judith Frydman

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2013 Jan 17; 152(1-2): 196–209. doi: 10.1016/j.cell.2012.12.001

PMCID:: PMC3553497

Abstract Article PDF–5.1M

Select item 520434818.

A novel translational control mechanism involving RNA structures within coding sequences

Jennifer Jungfleisch, Danny D. Nedialkova, Ivan Dotu, Katherine E. Sloan, Neus Martinez-Bosch, Lukas Brüning, Emanuele Raineri, Pilar Navarro, Markus T. Bohnsack, Sebastian A. Leidel, Juana Díez

Genome Res. 2017 Jan; 27(1): 95–106. doi: 10.1101/gr.209015.116

Correction in:: Genome Res. 2017 Apr; 27(4): 663.

PMCID:: PMC5204348

Abstract Article PDF–1.3M

Select item 1023336819.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 278735320.

Purification of Nuclear Poly(A)-binding Protein Nab2 Reveals Association with the Yeast Transcriptome and a Messenger Ribonucleoprotein Core Structure

Julien Batisse, Claire Batisse, Aidan Budd, Bettina Böttcher, Ed Hurt

J Biol Chem. 2009 Dec 11; 284(50): 34911–34917. Published online 2009 Oct 19. doi: 10.1074/jbc.M109.062034

PMCID:: PMC2787353

Abstract Article PDF–3.8M

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