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Select item 61559891.

Functional and Biochemical Characterization of Dib1’s Role in pre-Messenger RNA Splicing

Christian C. Schreib, Emily K. Bowman, Cody A. Hernandez, Amber L. Lucas, Camille H.S. Potts, Corina Maeder

J Mol Biol. Author manuscript; available in PMC 2019 May 25.

Published in final edited form as: J Mol Biol. 2018 May 25; 430(11): 1640–1651. Published online 2018 Apr 30. doi: 10.1016/j.jmb.2018.04.027

PMCID:: PMC6155989

Abstract Article PDF–1.0M

Select item 42599692.

Compound Heterozygosity of Low-Frequency Promoter Deletions and Rare Loss-of-Function Mutations in TXNL4A Causes Burn-McKeown Syndrome

Dagmar Wieczorek, William G. Newman, Thomas Wieland, Tea Berulava, Maria Kaffe, Daniela Falkenstein, Christian Beetz, Elisabeth Graf, Thomas Schwarzmayr, Sofia Douzgou, Jill Clayton-Smith, Sarah B. Daly, Simon G. Williams, Sanjeev S. Bhaskar, Jill E. Urquhart, Beverley Anderson, James O’Sullivan, Odile Boute, Jasmin Gundlach, Johanna Christina Czeschik, Anthonie J. van Essen, Filiz Hazan, Sarah Park, Anne Hing, Alma Kuechler, Dietmar R. Lohmann, Kerstin U. Ludwig, Elisabeth Mangold, Laura Steenpaß, Michael Zeschnigk, Johannes R. Lemke, Charles Marques Lourenco, Ute Hehr, Eva-Christina Prott, Melanie Waldenberger, Anne C. Böhmer, Bernhard Horsthemke, Raymond T. O’Keefe, Thomas Meitinger, John Burn, Hermann-Josef Lüdecke, Tim M. Strom

Am J Hum Genet. 2014 Dec 4; 95(6): 698–707. doi: 10.1016/j.ajhg.2014.10.014

PMCID:: PMC4259969

Abstract Article PDF–1.3M

Select item 27908793.

An analytical platform for mass spectrometry-based identification and chemical analysis of RNA in ribonucleoprotein complexes

Masato Taoka, Yoshio Yamauchi, Yuko Nobe, Shunpei Masaki, Hiroshi Nakayama, Hideaki Ishikawa, Nobuhiro Takahashi, Toshiaki Isobe

Nucleic Acids Res. 2009 Nov; 37(21): e140. Published online 2009 Sep 9. doi: 10.1093/nar/gkp732

PMCID:: PMC2790879

Abstract Article PDF–580K

Select item 220604.

Purification of the yeast U4/U6⋅U5 small nuclear ribonucleoprotein particle and identification of its proteins

Scott W. Stevens, John Abelson

Proc Natl Acad Sci U S A. 1999 Jun 22; 96(13): 7226–7231. doi: 10.1073/pnas.96.13.7226

PMCID:: PMC22060

Abstract Article PDF–154K

Select item 13701975.

Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae.

S W Stevens, I Barta, H Y Ge, R E Moore, M K Young, T D Lee, J Abelson

RNA. 2001 Nov; 7(11): 1543–1553.

PMCID:: PMC1370197

Summary PDF–755K

Select item 47622016.

CryoEM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution

Thi Hoang Duong Nguyen, Wojciech P. Galej, Xiao-chen Bai, Chris Oubridge, Andrew J. Newman, Sjors H. W. Scheres, Kiyoshi Nagai

Nature. Author manuscript; available in PMC 2016 Aug 18.

Published in final edited form as: Nature. 2016 Feb 18; 530(7590): 298–302. Published online 2016 Feb 1. doi: 10.1038/nature16940

PMCID:: PMC4762201

Abstract Article PDF–6.1M

Select item 47568257.

Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly

Allison L. Didychuk, Eric J. Montemayor, David A. Brow, Samuel E. Butcher

Nucleic Acids Res. 2016 Feb 18; 44(3): 1398–1410. Published online 2015 Dec 15. doi: 10.1093/nar/gkv1374

PMCID:: PMC4756825

Abstract Article PDF–9.3M

Select item 45367688.

The architecture of the spliceosomal U4/U6.U5 tri-snRNP

Thi Hoang Duong Nguyen, Wojciech P. Galej, Xiao-chen Bai, Christos G. Savva, Andrew J. Newman, Sjors H. W. Scheres, Kiyoshi Nagai

Nature. Author manuscript; available in PMC 2016 Jan 2.

Published in final edited form as: Nature. 2015 Jul 2; 523(7558): 47–52. Published online 2015 Jun 24. doi: 10.1038/nature14548

PMCID:: PMC4536768

Abstract Article PDF–6.7M

Select item 11715289.

Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

A Gottschalk, G Neubauer, J Banroques, M Mann, R Lührmann, P Fabrizio

EMBO J. 1999 Aug 16; 18(16): 4535–4548. doi: 10.1093/emboj/18.16.4535

PMCID:: PMC1171528

Summary PDF–407K

Select item 438105310.

Brr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding

Lingdi Zhang, Xueni Li, Ryan C. Hill, Yan Qiu, Wenzheng Zhang, Kirk C. Hansen, Rui Zhao

Nucleic Acids Res. 2015 Mar 31; 43(6): 3286–3297. Published online 2015 Feb 10. doi: 10.1093/nar/gkv062

PMCID:: PMC4381053

Abstract Article PDF–5.3M

Select item 471892211.

Systematic humanization of yeast genes reveals conserved functions and genetic modularity

Aashiq H. Kachroo, Jon M. Laurent, Christopher M. Yellman, Austin G. Meyer, Claus O. Wilke, Edward M. Marcotte

Science. Author manuscript; available in PMC 2016 Jan 20.

Published in final edited form as: Science. 2015 May 22; 348(6237): 921–925. doi: 10.1126/science.aaa0769

PMCID:: PMC4718922

Abstract Article PDF–2.0M

Select item 464965012.

Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants

Akil Hamza, Erik Tammpere, Megan Kofoed, Christelle Keong, Jennifer Chiang, Guri Giaever, Corey Nislow, Philip Hieter

Genetics. 2015 Nov; 201(3): 1263–1274. Published online 2015 Sep 9. doi: 10.1534/genetics.115.181099

PMCID:: PMC4649650

Abstract Article PDF–6.2M

Select item 358713813.

Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing

Shravan Kumar Mishra, Tim Ammon, Grzegorz M. Popowicz, Marcin Krajewski, Roland J. Nagel, Manuel Ares, Jr, Tad A. Holak, Stefan Jentsch

Nature. Author manuscript; available in PMC 2013 Mar 4.

Published in final edited form as: Nature. 2011 May 25; 474(7350): 173–178. Published online 2011 May 25. doi: 10.1038/nature10143

PMCID:: PMC3587138

Abstract Article PDF–1.5M

Select item 658956614.

Selective defects in gene expression control genome instability in yeast splicing mutants

Annie S. Tam, Tianna S. Sihota, Karissa L. Milbury, Anni Zhang, Veena Mathew, Peter C. Stirling

Mol Biol Cell. 2019 Jan 15; 30(2): 191–200. doi: 10.1091/mbc.E18-07-0439

PMCID:: PMC6589566

Abstract Article PDF–5.1M

Select item 315945815.

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells

Beate Schwer, Hediye Erdjument-Bromage, Stewart Shuman

Nucleic Acids Res. 2011 Aug; 39(15): 6715–6728. Published online 2011 May 10. doi: 10.1093/nar/gkr279

PMCID:: PMC3159458

Abstract Article PDF–8.4M

Select item 307093816.

Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes

Joseph Fasolo, Andrea Sboner, Mark G.F. Sun, Haiyuan Yu, Rui Chen, Donald Sharon, Philip M. Kim, Mark Gerstein, Michael Snyder

Genes Dev. 2011 Apr; 25(7): 767–778. doi: 10.1101/gad.1998811

PMCID:: PMC3070938

Abstract Article PDF–1.2M

Select item 309130117.

Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins

Tanja Scherrer, Christian Femmer, Ralph Schiess, Ruedi Aebersold, André P Gerber

Genome Biol. 2011; 12(1): R3. Published online 2011 Jan 13. doi: 10.1186/gb-2011-12-1-r3

PMCID:: PMC3091301

Abstract Article PDF–1.3M

Select item 328593318.

La-motif–dependent mRNA association with Slf1 promotes copper detoxification in yeast

Luca Schenk, Dominik M. Meinel, Katja Strässer, André P. Gerber

RNA. 2012 Mar; 18(3): 449–461. doi: 10.1261/rna.028506.111

PMCID:: PMC3285933

Abstract Article PDF–812K

Select item 484875819.

An inter‐species protein–protein interaction network across vast evolutionary distance

Quan Zhong, Samuel J Pevzner, Tong Hao, Yang Wang, Roberto Mosca, Jörg Menche, Mikko Taipale, Murat Taşan, Changyu Fan, Xinping Yang, Patrick Haley, Ryan R Murray, Flora Mer, Fana Gebreab, Stanley Tam, Andrew MacWilliams, Amélie Dricot, Patrick Reichert, Balaji Santhanam, Lila Ghamsari, Michael A Calderwood, Thomas Rolland, Benoit Charloteaux, Susan Lindquist, Albert‐László Barabási, David E Hill, Patrick Aloy, Michael E Cusick, Yu Xia, Frederick P Roth, Marc Vidal

Mol Syst Biol. 2016 Apr; 12(4): 865. Published online 2016 Apr 23. doi: 10.15252/msb.20156484

PMCID:: PMC4848758

Abstract Article PDF–2.1M

Select item 257886020.

Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast

Yuko Hasegawa, Kenji Irie, André P. Gerber

RNA. 2008 Nov; 14(11): 2333–2347. doi: 10.1261/rna.1016508

PMCID:: PMC2578860

Abstract Article PDF–1.3M

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