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Select item 112420951.

Hypomethylation of the RUNX2 Gene Is a New Potential Biomarker of Primary Osteoporosis in Men and Women

Bulat Yalaev, Anton Tyurin, Karina Akhiiarova, Rita Khusainova

Int J Mol Sci. 2024 Jul; 25(13): 7312. Published online 2024 Jul 3. doi: 10.3390/ijms25137312

PMCID:: PMC11242095

Abstract Article PDF–1.8M

Select item 111582112.

Runx2 in human breast carcinoma: its potential roles in cancer progression

Yoshiaki Onodera, Yasuhiro Miki, Takashi Suzuki, Kiyoshi Takagi, Jun‐ichi Akahira, Takuya Sakyu, Mika Watanabe, Satoshi Inoue, Takanori Ishida, Noriaki Ohuchi, Hironobu Sasano

Cancer Sci. 2010 Dec; 101(12): 2670–2675. Published online 2010 Oct 12. doi: 10.1111/j.1349-7006.2010.01742.x

PMCID:: PMC11158211

Abstract Article PDF–274K

Select item 108268223.

RUNX2 prompts triple negative breast cancer drug resistance through TGF-β pathway regulating breast cancer stem cells

Fengxu Lv, Wentao Si, Xiaodan Xu, Xiaogang He, Ying Wang, Yetian Li, Feifei Li

Neoplasia. 2024 Feb; 48: 100967. Published online 2024 Jan 13. doi: 10.1016/j.neo.2024.100967

PMCID:: PMC10826822

Abstract Article PDF–24M

Select item 108046644.

Scopolamine regulates the osteogenic differentiation of human periodontal ligament stem cells through lactylation modification of RUNX2 protein

Ying Wu, Pan Gong

Pharmacol Res Perspect. 2024 Feb; 12(1): e1169. Published online 2024 Jan 23. doi: 10.1002/prp2.1169

PMCID:: PMC10804664

Abstract Article PDF–2.4M

Select item 103748875.

Functional consequences of C-terminal mutations in RUNX2

Sermporn Thaweesapphithak, Thanakorn Theerapanon, Khanti Rattanapornsompong, Narin Intarak, Pimsiri Kanpittaya, Vorapat Trachoo, Thantrira Porntaveetus, Vorasuk Shotelersuk

Sci Rep. 2023; 13: 12202. Published online 2023 Jul 27. doi: 10.1038/s41598-023-39293-1

PMCID:: PMC10374887

Abstract Article PDF–4.3M

Select item 101390766.

RUNX2 and Cancer

Tsung-Chieh Lin

Int J Mol Sci. 2023 Apr; 24(8): 7001. Published online 2023 Apr 10. doi: 10.3390/ijms24087001

PMCID:: PMC10139076

Abstract Article PDF–3.1M

Select item 101208677.

Complement Cross Talks With H-K-ATPase to Upregulate Runx2 in Human Aortic Valve Interstitial Cells

Xin-sheng Deng, Xianzhong Meng, David Fullerton, Matthew Stone, John Iguidbashian, James Jaggers

J Surg Res. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: J Surg Res. 2023 Jun; 286: 118–126. Published online 2023 Feb 21. doi: 10.1016/j.jss.2022.12.028

PMCID:: PMC10120867

Abstract Article PDF–1.4M

Select item 97604298.

RUNX2 stabilization by long non-coding RNAs contributes to hypertrophic changes in human chondrocytes

Dong Suk Yoon, Eun-Ji Kim, Sehee Cho, Soyeong Jung, Kyoung-Mi Lee, Kwang Hwan Park, Jin Woo Lee, Sung-Hwan Kim

Int J Biol Sci. 2023; 19(1): 13–33. Published online 2023 Jan 1. doi: 10.7150/ijbs.74895

PMCID:: PMC9760429

Abstract Article PDF–3.5M

Select item 96136649.

RUNX2 recruits the NuRD(MTA1)/CRL4B complex to promote breast cancer progression and bone metastasis

Xin Yin, Xu Teng, Tianyu Ma, Tianshu Yang, Jingyao Zhang, Miaomiao Huo, Wei Liu, Yunkai Yang, Baowen Yuan, Hefen Yu, Wei Huang, Yan Wang

Cell Death Differ. 2022 Nov; 29(11): 2203–2217. Published online 2022 May 9. doi: 10.1038/s41418-022-01010-2

PMCID:: PMC9613664

Abstract Article PDF–8.6M

Select item 932248410.

A Novel 90-kbp Deletion of RUNX2 Associated with Cleidocranial Dysplasia

Yanli Zhang, Xiaohong Duan

Genes (Basel) 2022 Jul; 13(7): 1128. Published online 2022 Jun 23. doi: 10.3390/genes13071128

PMCID:: PMC9322484

Abstract Article PDF–1.2M

Select item 925901411.

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

Sigrid Wahlen, Filip Matthijssens, Wouter Van Loocke, Sylvie Taveirne, Laura Kiekens, Eva Persyn, Els Van Ammel, Zenzi De Vos, Stijn De Munter, Patrick Matthys, Filip Van Nieuwerburgh, Tom Taghon, Bart Vandekerckhove, Pieter Van Vlierberghe, Georges Leclercq

eLife. 2022; 11: e80320. Published online 2022 Jul 6. doi: 10.7554/eLife.80320

PMCID:: PMC9259014

Abstract Article PDF–2.2M

Select item 923930012.

Cleidocranial dysplasia and novel RUNX2 variants: dental, craniofacial, and osseous manifestations

Sermporn THAWEESAPPHITHAK, Jirawat SAENGSIN, Wuttichart KAMOLVISIT, Thanakorn THEERAPANON, Thantrira PORNTAVEETUS, Vorasuk SHOTELERSUK

J Appl Oral Sci. 2022; 30: e20220028. Published online 2022 Jun 6. doi: 10.1590/1678-7757-2022-0028

PMCID:: PMC9239300

Abstract Article PDF–6.9M

Select item 868717513.

Integrated expression analysis revealed RUNX2 upregulation in lung squamous cell carcinoma tissues

Da‐Ping Yang, Hui‐Ping Lu, Gang Chen, Jie Yang, Li Gao, Jian‐Hua Song, Shang‐Wei Chen, Jun‐Xian Mo, Jin‐Liang Kong, Zhong‐Qing Tang, Chang‐Bo Li, Hua‐Fu Zhou, Lin‐Jie Yang

IET Syst Biol. 2020 Oct; 14(5): 252–260. Published online 2020 Sep 15. doi: 10.1049/iet-syb.2020.0063

PMCID:: PMC8687175

Abstract Article PDF–3.2M

Select item 840942314.

The transcription factor RUNX2 fuels YAP1 signaling and gastric cancer tumorigenesis

Zhengjun Guo, Kai Zhou, Qiang Wang, Yusheng Huang, Jia Ji, Yuan Peng, Xiaoyue Zhang, Taihao Zheng, Zhen Zhang, Daochen Chong, Zhenzhou Yang

Cancer Sci. 2021 Sep; 112(9): 3533–3544. Published online 2021 Jul 16. doi: 10.1111/cas.15045

PMCID:: PMC8409423

Abstract Article PDF–2.6M

Select item 833439415.

Identification of a Novel Splice Site Mutation in RUNX2 Gene in a Family with Rare Autosomal Dominant Cleidocranial Dysplasia

Ebrahim Jamali, Raziyeh Khalesi, Fatemeh Bitarafan, Navid Almadani, Masoud Garshasbi

Iran Biomed J. 2021 Jul; 25(4): 297–302. Published online 2020 Oct 19. doi: 10.52547/ibj.25.4.297

PMCID:: PMC8334394

Abstract Article PDF–652K

Select item 832629716.

Complement up-regulates Runx-2 to induce pro-fibrogenic change in aortic valve interstitial cells

Xin-sheng Deng, Xianzhong Meng, David Fullerton, Matthew Stone, James Jaggers

Ann Thorac Surg. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Ann Thorac Surg. 2021 Dec; 112(6): 1962–1972. Published online 2021 Feb 3. doi: 10.1016/j.athoracsur.2020.12.058

PMCID:: PMC8326297

Abstract Article PDF–1.5M

Select item 795460517.

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia

Filip Matthijssens, Nitesh D. Sharma, Monique Nysus, Christian K. Nickl, Huining Kang, Dominique R. Perez, Beatrice Lintermans, Wouter Van Loocke, Juliette Roels, Sofie Peirs, Lisa Demoen, Tim Pieters, Lindy Reunes, Tim Lammens, Barbara De Moerloose, Filip Van Nieuwerburgh, Dieter L. Deforce, Laurence C. Cheung, Rishi S. Kotecha, Martijn D.P. Risseeuw, Serge Van Calenbergh, Takeshi Takarada, Yukio Yoneda, Frederik W. van Delft, Richard B. Lock, Seth D. Merkley, Alexandre Chigaev, Larry A. Sklar, Charles G. Mullighan, Mignon L. Loh, Stuart S. Winter, Stephen P. Hunger, Steven Goossens, Eliseo F. Castillo, Wojciech Ornatowski, Pieter Van Vlierberghe, Ksenia Matlawska-Wasowska

J Clin Invest. 2021 Mar 15; 131(6): e141566. Published online 2021 Mar 15. doi: 10.1172/JCI141566

PMCID:: PMC7954605

Abstract Article PDF–9.5M

Select item 770600218.

Treatment of keloids through Runx2 siRNA-induced inhibition of the PI3K/AKT signaling pathway

Wenchang Lv, Min Wu, Yuping Ren, Xiao Luo, Weijie Hu, Qi Zhang, Yiping Wu

Mol Med Rep. 2021 Jan; 23(1): 55. Published online 2020 Nov 16. doi: 10.3892/mmr.2020.11693

PMCID:: PMC7706002

Abstract Article PDF–2.0M

Select item 735899119.

Gain-of-function variants and overexpression of RUNX2 in patients with nonsyndromic midline craniosynostosis

Araceli Cuellar, Krithi Bala, Lorena Di Pietro, Marta Barba, Garima Yagnik, Jia Lie Liu, Christina Stevens, David J. Hur, Roxann G. Ingersoll, Cristina M. Justice, Hicham Drissi, Jinoh Kim, Wanda Lattanzi, Simeon A. Boyadjiev

Bone. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: Bone. 2020 Aug; 137: 115395. Published online 2020 Apr 30. doi: 10.1016/j.bone.2020.115395

PMCID:: PMC7358991

Abstract Article PDF–1.9M

Select item 718905820.

Functions of Exogenous RUNX2 in Giant Cell Tumor of Bone In Vitro

Yuan‐han Jin, Jing Zhang, Hao Zhu, Gen‐tao Fan, Guang‐xin Zhou

Orthop Surg. 2020 Apr; 12(2): 668–678. Published online 2020 Mar 10. doi: 10.1111/os.12568

PMCID:: PMC7189058

Abstract Article PDF–2.7M

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