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Select item 67776311.

Phenotypic spectrum associated with a CRADD founder variant underlying frontotemporal predominant pachygyria in the Finnish population

Daniel L. Polla, Elisa Rahikkala, Michaela K. Bode, Tuomo Määttä, Teppo Varilo, Thyrza Loman, Anju K. Philips, Mitja Kurki, Aarno Palotie, Jarmo Körkkö, Päivi Vieira, Kristiina Avela, Valérie Jacquemin, Isabelle Pirson, Marc Abramowicz, Arjan P. M. de Brouwer, Outi Kuismin, Hans van Bokhoven, Irma Järvelä

Eur J Hum Genet. 2019 Aug; 27(8): 1235–1243. Published online 2019 Mar 26. doi: 10.1038/s41431-019-0383-8

Correction in:: Eur J Hum Genet. 2020 Apr; 28(4): 532.

PMCID:: PMC6777631

Abstract Article PDF–927K

Select item 30899642.

LBH589, a deacetylase inhibitor, induces apoptosis in adult T-cell leukemia/lymphoma cells via activation of a novel RAIDD-caspase-2 pathway

H Hasegawa, Y Yamada, K Tsukasaki, N Mori, K Tsuruda, D Sasaki, T Usui, A Osaka, S Atogami, C Ishikawa, Y Machijima, S Sawada, T Hayashi, Y Miyazaki, S Kamihira

Leukemia. 2011 Apr; 25(4): 575–587. Published online 2011 Jan 18. doi: 10.1038/leu.2010.315

PMCID:: PMC3089964

Abstract Article PDF–942K

Select item 30629653.

In vitro Reconstitution of the Interactions in the PIDDosome

Tae-ho Jang, Chao Zheng, Hao Wu, Ju-Hong Jeon, Hyun Ho Park

Apoptosis. Author manuscript; available in PMC 2011 Mar 23.

Published in final edited form as: Apoptosis. 2010 Dec; 15(12): 1444–1452. doi: 10.1007/s10495-010-0544-2

PMCID:: PMC3062965

Abstract Article PDF–904K

Select item 29029804.

Crystal Structure of RAIDD Death Domain Implicates Potential Mechanism of PIDDosome Assembly

Hyun Ho Park, Hao Wu

J Mol Biol. Author manuscript; available in PMC 2010 Jul 13.

Published in final edited form as: J Mol Biol. 2006 Mar 24; 357(2): 358–364. Published online 2006 Jan 11. doi: 10.1016/j.jmb.2005.12.082

PMCID:: PMC2902980

Abstract Article PDF–1.7M

Select item 27055035.

Purification, Crystallization and Preliminary X-ray Crystallographic Studies of RAIDD Death-Domain (DD)

Tae-ho Jang, Hyun Ho Park

Int J Mol Sci. 2009 Jun; 10(6): 2501–2509. Published online 2009 Jun 3. doi: 10.3390/ijms10062501

PMCID:: PMC2705503

Abstract Article PDF–282K

Select item 41392146.

The Adaptor CRADD/RAIDD Controls Activation of Endothelial Cells by Proinflammatory Stimuli

Huan Qiao, Yan Liu, Ruth A. Veach, Lukasz Wylezinski, Jacek Hawiger

J Biol Chem. 2014 Aug 8; 289(32): 21973–21983. Published online 2014 Jun 23. doi: 10.1074/jbc.M114.588723

PMCID:: PMC4139214

Abstract Article PDF–2.1M

Select item 23301817.

Crystallization and preliminary X-ray crystallographic studies of the oligomeric death-domain complex between PIDD and RAIDD

Hyun Ho Park, Hao Wu

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1; 63(Pt 3): 229–232. Published online 2007 Feb 23. doi: 10.1107/S1744309107007889

PMCID:: PMC2330181

Abstract Article PDF–247K

Select item 50979458.

Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant

Nataliya Di Donato, Ying Y. Jean, A. Murat Maga, Briana D. Krewson, Alison B. Shupp, Maria I. Avrutsky, Achira Roy, Sarah Collins, Carissa Olds, Rebecca A. Willert, Agnieszka M. Czaja, Rachel Johnson, Jessi A. Stover, Steven Gottlieb, Deborah Bartholdi, Anita Rauch, Amy Goldstein, Victoria Boyd-Kyle, Kimberly A. Aldinger, Ghayda M. Mirzaa, Anke Nissen, Karlla W. Brigatti, Erik G. Puffenberger, Kathleen J. Millen, Kevin A. Strauss, William B. Dobyns, Carol M. Troy, Robert N. Jinks

Am J Hum Genet. 2016 Nov 3; 99(5): 1117–1129. Published online 2016 Oct 20. doi: 10.1016/j.ajhg.2016.09.010

PMCID:: PMC5097945

Abstract Article PDF–1.3M

Select item 46192889.

PIDDosome Expression and the Role of Caspase-2 Activation for Chemotherapy-Induced Apoptosis in RCCs

Sebastian Heikaus, Igor Pejin, Helmut Erich Gabbert, Uwe Ramp, Csaba Mahotka

Cell Oncol. 2010; 32(1-2): 29–42. Published online 2010 Feb 4. doi: 10.3233/CLO-2009-0492

PMCID:: PMC4619288

Abstract PDF–543K

Select item 445819310.

An Inhibitor of PIDDosome Formation

Ruth Thompson, Richa B. Shah, Peter H. Liu, Yogesh Gupta, Kiyohiro Ando, Aneel K. Aggarwal, Samuel Sidi

Mol Cell. Author manuscript; available in PMC 2016 Jun 4.

Published in final edited form as: Mol Cell. 2015 Jun 4; 58(5): 767–779. Published online 2015 Apr 30. doi: 10.1016/j.molcel.2015.03.034

PMCID:: PMC4458193

Abstract Article PDF–2.5M

Select item 344462011.

PIDD Death-Domain Phosphorylation by ATM Controls Prodeath Versus Prosurvival PIDDosome Signaling

Kiyohiro Ando, Jennifer L. Kernan, Peter H. Liu, Takaomi Sanda, Emmanuelle Logette, Jurg Tschopp, A. Thomas Look, Jianlong Wang, Lisa Bouchier-Hayes, Samuel Sidi

Mol Cell. Author manuscript; available in PMC 2013 Sep 14.

Published in final edited form as: Mol Cell. 2012 Sep 14; 47(5): 681–693. Published online 2012 Jul 30. doi: 10.1016/j.molcel.2012.06.024

PMCID:: PMC3444620

Abstract Article PDF–2.3M

Select item 178237712.

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-κB pathway

Antoine Tinel, Sophie Janssens, Saskia Lippens, Solange Cuenin, Emmanuelle Logette, Bastienne Jaccard, Manfredo Quadroni, Jürg Tschopp

EMBO J. 2007 Jan 10; 26(1): 197–208. Published online 2006 Dec 7. doi: 10.1038/sj.emboj.7601473

PMCID:: PMC1782377

Abstract Article PDF–393K

Select item 345893013.

Cytoplasmic and Nuclear Anti-Apoptotic Roles of αB-Crystallin in Retinal Pigment Epithelial Cells

Woo Jin Jeong, Jee Hyun Rho, Young Geol Yoon, Seung Hee Yoo, Na Young Jeong, Won Yeol Ryu, Hee Bae Ahn, Woo Chan Park, Sae Heun Rho, Hee Seong Yoon, Yung Hyun Choi, Young Hyun Yoo

PLoS One. 2012; 7(9): e45754. Published online 2012 Sep 26. doi: 10.1371/journal.pone.0045754

PMCID:: PMC3458930

Abstract Article PDF–4.7M

Select item 604385014.

Dimer‐specific immunoprecipitation of active caspase‐2 identifies TRAF proteins as novel activators

Alexander C Robeson, Kelly R Lindblom, Jeffrey Wojton, Sally Kornbluth, Kenkyo Matsuura

EMBO J. 2018 Jul 13; 37(14): e97072. Published online 2018 Jun 6. doi: 10.15252/embj.201797072

PMCID:: PMC6043850

Abstract Article PDF–2.1M

Select item 298891215.

The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

Liwei Wang, Jin Kuk Yang, Venkataraman Kabaleeswaran, Amanda J. Rice, Anthony C. Cruz, Ah Young Park, Qian Yin, Ermelinda Damko, Se Bok Jang, Stefan Raunser, Carol V. Robinson, Richard M. Siegel, Thomas Walz, Hao Wu

Nat Struct Mol Biol. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Nat Struct Mol Biol. 2010 Nov; 17(11): 1324–1329. Published online 2010 Oct 10. doi: 10.1038/nsmb.1920

PMCID:: PMC2988912

Abstract Article PDF–1.6M

Select item 326015316.

Genetic Mapping and Exome Sequencing Identify Variants Associated with Five Novel Diseases

Erik G. Puffenberger, Robert N. Jinks, Carrie Sougnez, Kristian Cibulskis, Rebecca A. Willert, Nathan P. Achilly, Ryan P. Cassidy, Christopher J. Fiorentini, Kory F. Heiken, Johnny J. Lawrence, Molly H. Mahoney, Christopher J. Miller, Devika T. Nair, Kristin A. Politi, Kimberly N. Worcester, Roni A. Setton, Rosa DiPiazza, Eric A. Sherman, James T. Eastman, Christopher Francklyn, Susan Robey-Bond, Nicholas L. Rider, Stacey Gabriel, D. Holmes Morton, Kevin A. Strauss

PLoS One. 2012; 7(1): e28936. Published online 2012 Jan 17. doi: 10.1371/journal.pone.0028936

PMCID:: PMC3260153

Abstract Article PDF–6.2M

Select item 546101517.

NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus

Kiyohiro Ando, Melissa J. Parsons, Richa B. Shah, Chloé I. Charendoff, Sheré L. Paris, Peter H. Liu, Sara R. Fassio, Brittany A. Rohrman, Ruth Thompson, Andrew Oberst, Samuel Sidi, Lisa Bouchier-Hayes

J Cell Biol. 2017 Jun 5; 216(6): 1795–1810. doi: 10.1083/jcb.201608095

PMCID:: PMC5461015

Abstract Article PDF–2.8M

Select item 316028318.

Caspase-2-mediated cleavage of Mdm2 creates p53-induced positive feedback loop

Trudy G. Oliver, Etienne Meylan, Gregory P. Chang, Wen Xue, James R. Burke, Timothy J. Humpton, Diana Hubbard, Arjun Bhutkar, Tyler Jacks

Mol Cell. Author manuscript; available in PMC 2012 Jan 8.

Published in final edited form as: Mol Cell. 2011 Jul 8; 43(1): 57–71. doi: 10.1016/j.molcel.2011.06.012

PMCID:: PMC3160283

Abstract Article PDF–1.5M

Select item 313194419.

PIDD orchestrates translesion DNA synthesis in response to UV irradiation

E Logette, S Schuepbach-Mallepell, M J Eckert, X H Leo, B Jaccard, C Manzl, A Tardivel, A Villunger, M Quadroni, O Gaide, J Tschopp

Cell Death Differ. 2011 Jun; 18(6): 1036–1045. Published online 2011 Mar 18. doi: 10.1038/cdd.2011.19

PMCID:: PMC3131944

Abstract Article PDF–547K

Select item 335172920.

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses

Nicolas Simonis, Jean-François Rual, Irma Lemmens, Mathieu Boxus, Tomoko Hirozane-Kishikawa, Jean-Stéphane Gatot, Amélie Dricot, Tong Hao, Didier Vertommen, Sébastien Legros, Sarah Daakour, Niels Klitgord, Maud Martin, Jean-François Willaert, Franck Dequiedt, Vincent Navratil, Michael E Cusick, Arsène Burny, Carine Van Lint, David E Hill, Jan Tavernier, Richard Kettmann, Marc Vidal, Jean-Claude Twizere

Retrovirology. 2012; 9: 26. Published online 2012 Mar 29. doi: 10.1186/1742-4690-9-26

PMCID:: PMC3351729

Abstract Article PDF–1.3M

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