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Select item 97385221.

A Dual Role for FADD in Human Precursor T-Cell Neoplasms

José Luis Marín-Rubio, Laura Vela-Martín, Jack Gudgeon, Eduardo Pérez-Gómez, Frances R. Sidgwick, Matthias Trost, Debbie L. Cunningham, Javier Santos, José Fernández-Piqueras, María Villa-Morales

Int J Mol Sci. 2022 Dec; 23(23): 15157. Published online 2022 Dec 2. doi: 10.3390/ijms232315157

PMCID:: PMC9738522

Abstract Article PDF–2.5M

Select item 91349092.

The Classical Apoptotic Adaptor FADD Regulates Glycolytic Capacity in Acute Lymphoblastic Leukemia

Wenzhao Zhou, Yueyang Lai, Jianhui Zhu, Xuebo Xu, Wenliang Yu, Zengzheng Du, Leyang Wu, Xuerui Zhang, Zichun Hua

Int J Biol Sci. 2022; 18(8): 3137–3155. Published online 2022 May 1. doi: 10.7150/ijbs.68016

PMCID:: PMC9134909

Abstract Article PDF–3.6M

Select item 79621943.

Loss of FADD and Caspases Affects the Response of T-Cell Leukemia Jurkat Cells to Anti-Cancer Drugs

Zuzana Mrkvová, Michaela Portešová, Iva Slaninová

Int J Mol Sci. 2021 Mar; 22(5): 2702. Published online 2021 Mar 7. doi: 10.3390/ijms22052702

PMCID:: PMC7962194

Abstract Article PDF–3.0M

Select item 72535124.

Novel Compound Heterozygote Variations in FADD Identified to Cause FAS-Associated Protein with Death Domain Deficiency

Lisa A. Kohn, Joseph D. Long, Edward C. Trope, Caroline Y. Kuo

J Clin Immunol. 2020; 40(4): 658–661. Published online 2020 Apr 29. doi: 10.1007/s10875-020-00779-6

PMCID:: PMC7253512

Article PDF–760K

Select item 71910445.

FADD Phosphorylation Modulates Blood Glucose Levels by Decreasing the Expression of Insulin-Degrading Enzyme

Yan Lin, Jia Liu, Jia Chen, Chun Yao, Yunwen Yang, Jie Wang, Hongqin Zhuang, Zi-Chun Hua

Mol Cells. 2020 Apr 30; 43(4): 373–383. Published online 2020 Mar 20. doi: 10.14348/molcells.2020.2198

PMCID:: PMC7191044

Abstract Article PDF–5.3M

Select item 56555116.

The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD)

Nichollas E. Scott, Cristina Giogha, Georgina L. Pollock, Catherine L. Kennedy, Andrew I. Webb, Nicholas A. Williamson, Jaclyn S. Pearson, Elizabeth L. Hartland

J Biol Chem. 2017 Oct 20; 292(42): 17337–17350. Published online 2017 Aug 31. doi: 10.1074/jbc.M117.805036

PMCID:: PMC5655511

Abstract Article PDF–2.7M

Select item 53600997.

Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample

Alfredo Ramos-Miguel, Jesús A. García-Sevilla, Alasdair M. Barr, Thomas A. Bayer, Peter Falkai, Sue E. Leurgans, Julie A. Schneider, David A. Bennett, William G. Honer, M. Julia García-Fuster

Mol Neurodegener. 2017; 12: 26. Published online 2017 Mar 20. doi: 10.1186/s13024-017-0168-x

PMCID:: PMC5360099

Abstract Article PDF–1.8M

Select item 53086668.

Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma

José L. Marín-Rubio, María C. de Arriba, María A. Cobos-Fernández, Laura González-Sánchez, Inmaculada Ors, Isabel Sastre, José Fernández-Piqueras, María Villa-Morales

Oncotarget. 2016 Sep 20; 7(38): 61485–61499. Published online 2016 Aug 18. doi: 10.18632/oncotarget.11370

PMCID:: PMC5308666

Abstract Article PDF–11M

Select item 50727079.

Clinical Implications of FADD Gene Amplification and Protein Overexpression in Taiwanese Oral Cavity Squamous Cell Carcinomas

Huei-Tzu Chien, Sou-De Cheng, Wen-Yu Chuang, Chun-Ta Liao, Hung-Ming Wang, Shiang-Fu Huang

PLoS One. 2016; 11(10): e0164870. Published online 2016 Oct 20. doi: 10.1371/journal.pone.0164870

PMCID:: PMC5072707

Abstract Article PDF–2.1M

Select item 408989010.

Expression of serine 194–phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non–Hodgkin lymphomas

Elias Drakos, Vasiliki Leventaki, Vasileios Atsaves, Ellen J. Schlette, Pei Lin, Francisco Vega, Roberto N. Miranda, Francois-Xavier Claret, L. Jeffrey Medeiros, George Z. Rassidakis

Hum Pathol. Author manuscript; available in PMC 2014 Jul 9.

Published in final edited form as: Hum Pathol. 2011 Aug; 42(8): 1117–1124. Published online 2011 Feb 11. doi: 10.1016/j.humpath.2010.11.002

PMCID:: PMC4089890

Abstract Article PDF–798K

Select item 402800911.

Prognostic significance of TMEM16A, PPFIA1, and FADD expression in invasive ductal carcinoma of the breast

Eun Ji Choi, Jeong A Yun, Sahrish Jabeen, Eun Kyoung Jeon, Hye Sung Won, Yoon Ho Ko, Su Young Kim

World J Surg Oncol. 2014; 12: 137. Published online 2014 May 1. doi: 10.1186/1477-7819-12-137

PMCID:: PMC4028009

Abstract Article PDF–1.1M

Select item 272402612.

Topology is the Principal Determinant in the Folding of a Complex All-alpha Greek Key Death Domain from Human FADD

Annette Steward, Gary S. McDowell, Jane Clarke

J Mol Biol. 2009 Jun 5; 389(2-3): 425–437. doi: 10.1016/j.jmb.2009.04.004

PMCID:: PMC2724026

Abstract Article

Select item 254698413.

The Interaction between Human Papillomavirus Type 16 and FADD Is Mediated by a Novel E6 Binding Domain

Sandy S. Tungteakkhun, Maria Filippova, Jonathan W. Neidigh, Nadja Fodor, Penelope J. Duerksen-Hughes

J Virol. 2008 Oct; 82(19): 9600–9614. Published online 2008 Jul 16. doi: 10.1128/JVI.00538-08

PMCID:: PMC2546984

Abstract Article PDF–936K

Select item 236118414.

FADD phosphorylation is critical for cell cycle regulation in breast cancer cells

S Matsuyoshi, K Shimada, M Nakamura, E Ishida, N Konishi

Br J Cancer. 2006 Feb 27; 94(4): 532–539. Published online 2006 Jan 31. doi: 10.1038/sj.bjc.6602955

PMCID:: PMC2361184

Abstract Article PDF–306K

Select item 119489915.

Phosphorylated FADD induces NF-κB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas

Guoan Chen, Mahaveer S. Bhojani, Andrew C. Heaford, Daniel C. Chang, Bharathi Laxman, Dafydd G. Thomas, Laura B. Griffin, James Yu, Julia M. Coppola, Thomas J. Giordano, Lin Lin, David Adams, Mark B. Orringer, Brian D. Ross, David G. Beer, Alnawaz Rehemtulla

Proc Natl Acad Sci U S A. 2005 Aug 30; 102(35): 12507–12512. Published online 2005 Aug 18. doi: 10.1073/pnas.0500397102

PMCID:: PMC1194899

Abstract Article PDF–451K

Select item 15089716.

Apoptosis and NF-κB: the FADD connection

Colin S. Duckett

J Clin Invest. 2002 Mar 1; 109(5): 579–580. doi: 10.1172/JCI15197

PMCID:: PMC150897

Article PDF–233K

Select item 1976317.

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

John Bertin, Robert C. Armstrong, Sabine Ottilie, David A. Martin, Yu Wang, Sean Banks, Guang-Hua Wang, Tatiana G. Senkevich, Emad S. Alnemri, Bernard Moss, Michael J. Lenardo, Kevin J. Tomaselli, Jeffrey I. Cohen

Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4): 1172–1176. doi: 10.1073/pnas.94.4.1172

PMCID:: PMC19763

Abstract Article PDF–382K

Select item 992845618.

FADD phosphorylation contributes to development of renal fibrosis by accelerating epithelial-mesenchymal transition

Yan Lin, Fangfang Cai, Xiaoyang Wang, Yunwen Yang, Yongzhe Ren, Chun Yao, Xiaoxing Yin, Hongqin Zhuang, Zichun Hua

Cell Cycle. 2023; 22(5): 580–595. Published online 2022 Oct 24. doi: 10.1080/15384101.2022.2136463

PMCID:: PMC9928456

Abstract Article PDF–3.7M

Select item 837349119.

Development and Validation of an Autophagy-Related Signature for Head and Neck Squamous Cell Carcinoma

Chang Liu, Wenling Wu, Meng Xu, Jinglin Mi, Longjiang Xu, Rensheng Wang

Biomed Res Int. 2021; 2021: 1028158. Published online 2021 Aug 11. doi: 10.1155/2021/1028158

PMCID:: PMC8373491

Abstract Article PDF–3.1M

Select item 786495920.

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Joanna L. Fox, Michelle A. Hughes, Xin Meng, Nikola A. Sarnowska, Ian R. Powley, Rebekah Jukes-Jones, David Dinsdale, Timothy J. Ragan, Louise Fairall, John W. R. Schwabe, Nobuhiro Morone, Kelvin Cain, Marion MacFarlane

Nat Commun. 2021; 12: 819. Published online 2021 Feb 5. doi: 10.1038/s41467-020-20806-9

PMCID:: PMC7864959

Abstract Article PDF–8.3M

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PMC Links for Gene (Select 8772) (165)
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PREDICTED: Homo sapiens serine/arginine repetitive matrix 2 (SRRM2), transcript ...
PREDICTED: Homo sapiens serine/arginine repetitive matrix 2 (SRRM2), transcript variant X1, mRNA
gi|2462548294|ref|XM_054379978.1|

Nucleotide
Homo sapiens cDNA clone IMAGE:5247589
Homo sapiens cDNA clone IMAGE:5247589
gi|83404932|gb|BC111027.1|

Nucleotide

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