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Select item 96724551.

GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T Cells

Yannick S. Rakké, Lucia Campos Carrascosa, Adriaan A. van Beek, Valeska de Ruiter, Rachelle S. van Gemerden, Michail Doukas, Pascal G. Doornebosch, Maarten Vermaas, Susan ter Borg, Erwin van der Harst, Peter Paul L.O. Coene, Mike Kliffen, Dirk J. Grünhagen, Cornelis Verhoef, Jan N.M. IJzermans, Jaap Kwekkeboom, Dave Sprengers

Cell Mol Gastroenterol Hepatol. 2023; 15(1): 77–97. Published online 2022 Sep 23. doi: 10.1016/j.jcmgh.2022.09.007

PMCID:: PMC9672455

Abstract Article PDF–3.4M

Select item 84752682.

GITR Promotes the Polarization of TFH-Like Cells in Helicobacter pylori-Positive Gastritis

Siqi Ming, Huan Yin, Xingyu Li, Sitang Gong, Guoliang Zhang, Yongjian Wu

Front Immunol. 2021; 12: 736269. Published online 2021 Sep 10. doi: 10.3389/fimmu.2021.736269

PMCID:: PMC8475268

Abstract Article PDF–3.7M

Select item 66193393.

GITR ligation enhances functionality of tumor‐infiltrating T cells in hepatocellular carcinoma

Adriaan A. van Beek, Guoying Zhou, Michail Doukas, Patrick P.C. Boor, Lisanne Noordam, Shanta Mancham, Lucia Campos Carrascosa, Marieke van der Heide‐Mulder, Wojciech G. Polak, Jan N.M. Ijzermans, Qiuwei Pan, Carlo Heirman, Ashley Mahne, Samantha L. Bucktrout, Marco J. Bruno, Dave Sprengers, Jaap Kwekkeboom

Int J Cancer. 2019 Aug 15; 145(4): 1111–1124. Published online 2019 Feb 27. doi: 10.1002/ijc.32181

PMCID:: PMC6619339

Abstract Article PDF–3.6M

Select item 44318244.

Expression of GITR Enhances Multiple Myeloma Cell Sensitivity to Bortezomib

Yinghao Zhao, Kun Zhang, Guangquan Li, Xingyi Zhang, Donglei Shi

PLoS One. 2015; 10(5): e0127334. Published online 2015 May 14. doi: 10.1371/journal.pone.0127334

PMCID:: PMC4431824

Abstract Article PDF–2.5M

Select item 36817755.

Novel Tumor Suppressor Function of Glucocorticoid-Induced TNF Receptor GITR in Multiple Myeloma

Yang Liu, Phong Quang, Esteban Braggio, Hai Ngo, Gayane Badalian-Very, Ludmila Flores, Yong Zhang, Antonio Sacco, Patricia Maiso, Abdel Kareem Azab, Feda Azab, Ruben Carrasco, Barrett J. Rollins, Aldo M. Roccaro, Irene M. Ghobrial

PLoS One. 2013; 8(6): e66982. Published online 2013 Jun 13. doi: 10.1371/journal.pone.0066982

PMCID:: PMC3681775

Abstract Article PDF–3.2M

Select item 31426386.

Association of functional GITR gene polymorphisms related to expression of glucocorticoid-induced tumour necrosis factor-receptor (GITR) molecules with prognosis of autoimmune thyroid disease

R Tomizawa, M Watanabe, N Inoue, K Takemura, Y Hidaka, T Akamizu, K Hayakawa, Y Iwatani

Clin Exp Immunol. 2011 Aug; 165(2): 141–147. doi: 10.1111/j.1365-2249.2011.04414.x

PMCID:: PMC3142638

Abstract Article PDF–886K

Select item 28721477.

Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family–Related Protein Triggering Enhances HIV-Specific CD4⁺ T Cell Cytokine Secretion and Protects HIV-Specific CD4⁺ T Cells from Apoptosis

Timothy P. Lahey, Suzanne D. Loisel, Wendy Wieland-Alter

J Infect Dis. Author manuscript; available in PMC 2010 May 18.

Published in final edited form as: J Infect Dis. 2007 Jul 1; 196(1): 43–49. Published online 2007 May 23. doi: 10.1086/518613

PMCID:: PMC2872147

Abstract Article PDF–525K

Select item 22763848.

Glucocorticoid-induced Tumor Necrosis Factor Receptor Negatively Regulates Activation of Human Primary Natural Killer (NK) Cells by Blocking Proliferative Signals and Increasing NK Cell Apoptosis

Baoying Liu, Zhuqing Li, Sankaranarayana P. Mahesh, Seth Pantanelli, Frank S. Hwang, Willie O. Siu, Robert B. Nussenblatt

J Biol Chem. 2008 Mar 28; 283(13): 8202–8210. doi: 10.1074/jbc.M708944200

PMCID:: PMC2276384

Abstract Article PDF–455K

Select item 95946899.

Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans

Annelie Shami, Dorothee Atzler, Laura A Bosmans, Holger Winkels, Svenja Meiler, Michael Lacy, Claudia van Tiel, Remco Ta Megens, Katrin Nitz, Jeroen Baardman, Pascal Kusters, Tom Seijkens, Christina Buerger, Aleksandar Janjic, Carlo Riccardi, Andreas Edsfeldt, Claudia Monaco, Mat Daemen, Menno P J de Winther, Jan Nilsson, Christian Weber, Norbert Gerdes, Isabel Gonçalves, Esther Lutgens

Eur Heart J. 2020 Aug 14; 41(31): 2938–2948. Published online 2020 Jul 30. doi: 10.1093/eurheartj/ehaa484

PMCID:: PMC9594689

Abstract Article PDF–2.3M

Select item 690040510.

NEDD4 Negatively Regulates GITR via Ubiquitination in Immune Microenvironment of Melanoma

Yu Guo, Lichang Yang, Shaorong Lei, Wuyuan Tan, Jianhong Long

Onco Targets Ther. 2019; 12: 10629–10637. Published online 2019 Dec 4. doi: 10.2147/OTT.S212317

PMCID:: PMC6900405

Abstract Article PDF–5.1M

Select item 682554211.

Characterization and comparison of GITR expression in solid tumors

Luis M Vence, Samantha L Bucktrout, Irina Fernandez, Jorge M Blando, Bevin M Smith, Ashley E Mahne, John C Lin, Terrence Park, Edward Pascua, Tao Sai, Javier Chaparro-Riggers, Sumit K Subudhi, Jorge A Scutti, Maria G Higa, Hao Zhao, Shalini S Yadav, Anirban Maitra, Ignacio I Wistuba, James P Allison, Padmanee Sharma

Clin Cancer Res. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Clin Cancer Res. 2019 Nov 1; 25(21): 6501–6510. Published online 2019 Jul 29. doi: 10.1158/1078-0432.CCR-19-0289

PMCID:: PMC6825542

Abstract Article PDF–724K

Select item 653005512.

Soluble glucocorticoid-induced tumor necrosis factor receptor regulates Helios expression in myasthenia gravis

Yi Li, Shumei Yang, Zhibin Li, Huanyu Meng, Wanling Jin, Huan Yang, Weifan Yin

J Transl Med. 2019; 17: 168. Published online 2019 May 22. doi: 10.1186/s12967-019-1916-1

PMCID:: PMC6530055

Abstract Article PDF–2.7M

Select item 441398113.

Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells

Simona Ronchetti, Erika Ricci, Maria Grazia Petrillo, Luigi Cari, Graziella Migliorati, Giuseppe Nocentini, Carlo Riccardi

J Immunol Res. 2015; 2015: 171520. Published online 2015 Apr 15. doi: 10.1155/2015/171520

PMCID:: PMC4413981

Abstract Article PDF–690K

Select item 420902314.

Expansion of regulatory GITR⁺CD25^low/-CD4⁺ T cells in systemic lupus erythematosus patients

Giuseppe Nocentini, Alessia Alunno, Maria Grazia Petrillo, Onelia Bistoni, Elena Bartoloni, Sara Caterbi, Simona Ronchetti, Graziella Migliorati, Carlo Riccardi, Roberto Gerli

Arthritis Res Ther. 2014; 16(5): 444. Published online 2014 Sep 26. doi: 10.1186/s13075-014-0444-x

PMCID:: PMC4209023

Abstract Article PDF–1.5M

Select item 372279115.

Correlation of Increased Blood Levels of GITR and GITRL with Disease Severity in Patients with Primary Sjögren's Syndrome

Xiaoxia Gan, Xiaoke Feng, Lei Gu, Wenfeng Tan, Xiaoxuan Sun, Chengyin Lv, Miaojia Zhang

Clin Dev Immunol. 2013; 2013: 340751. Published online 2013 Jul 7. doi: 10.1155/2013/340751

PMCID:: PMC3722791

Abstract Article PDF–2.8M

Select item 359443916.

Enhancement of Anti-Tumor Immunity Through Local Modulation of CTLA-4 and GITR by Dendritic Cells

Scott K. Pruitt, David Boczkowski, Nicole de Rosa, N. Rebecca Haley, Michael A. Morse, Douglas S. Tyler, Jens Dannull, Smita Nair

Eur J Immunol. Author manuscript; available in PMC 2013 Mar 12.

Published in final edited form as: Eur J Immunol. 2011 Dec; 41(12): 10.1002/eji.201141383. Published online 2011 Oct 26. doi: 10.1002/eji.201141383

PMCID:: PMC3594439

Abstract Article PDF–3.4M

Select item 2102917.

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

Giuseppe Nocentini, Linda Giunchi, Simona Ronchetti, Ludovic Tibor Krausz, Andrea Bartoli, Rosalba Moraca, Graziella Migliorati, Carlo Riccardi

Proc Natl Acad Sci U S A. 1997 Jun 10; 94(12): 6216–6221. doi: 10.1073/pnas.94.12.6216

PMCID:: PMC21029

Abstract Article PDF–618K

Select item 631840418.

Overexpression of Regulatory T Cell-Related Markers (FOXP3, CTLA-4 and GITR) by Peripheral Blood Mononuclear Cells from Patients with Breast Cancer

Esmat Khalife, Ali Khodadadi, Abdolhosein Talaeizadeh, Leila Rahimian, Maryam Nemati, Abdollah Jafarzadeh

Asian Pac J Cancer Prev. 2018; 19(11): 3019–3025. doi: 10.31557/APJCP.2018.19.11.3019

PMCID:: PMC6318404

Abstract Article PDF–319K

Select item 229109519.

Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states

Zhaocai Zhou, Xiaomin Song, Alan Berezov, Geng Zhang, Yanjing Li, Hongtao Zhang, Ramachandran Murali, Bin Li, Mark I. Greene

Proc Natl Acad Sci U S A. 2008 Apr 8; 105(14): 5465–5470. Published online 2008 Mar 31. doi: 10.1073/pnas.0711350105

PMCID:: PMC2291095

Abstract Article PDF–726K

Select item 214831020.

Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function

Kausik Chattopadhyay, Udupi A. Ramagopal, Arunika Mukhopadhaya, Vladimir N. Malashkevich, Teresa P. DiLorenzo, Michael Brenowitz, Stanley G. Nathenson, Steven C. Almo

Proc Natl Acad Sci U S A. 2007 Dec 4; 104(49): 19452–19457. Published online 2007 Nov 26. doi: 10.1073/pnas.0709264104

PMCID:: PMC2148310

Abstract Article PDF–730K

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PMC Links for Gene (Select 8784) (36)
PMC
Myosin-10 [Gavia stellata]
Myosin-10 [Gavia stellata]
gi|678175946|gb|KFV43902.1||gnl|WGS |N328_01896

Protein
CLEC4M C-type lectin domain family 4 member M [Homo sapiens]
CLEC4M C-type lectin domain family 4 member M [Homo sapiens]
Gene ID:10332

Gene
myosin-10 isoform X3 [Pongo abelii]
myosin-10 isoform X3 [Pongo abelii]
gi|2464109993|ref|XP_054391371.1|

Protein

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