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Items: 1 to 20 of 95

1.
Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC
Jan-Paul Gundlach, Charlotte Hauser, Franka Maria Schlegel, Christine Böger, Christian Röder, Christoph Röcken, Thomas Becker, Jan-Hendrik Egberts, Holger Kalthoff, Anna Trauzold
BMC Cancer. 2018; 18: 777. Published online 2018 Jul 31. doi: 10.1186/s12885-018-4688-8
PMCID:
PMC6069838
AbstractArticlePDF–1.5M
2.
Genetic association between TRAIL-R1 Thr209Arg and cancer susceptibility
Peiliang Geng, Jianjun Li, Ning Wang, Yunmei Liao, Juanjuan Ou, Rina Sa, Ganfeng Xie, Chen Liu, Hongtao Li, Lisha Xiang, Houjie Liang
Sci Rep. 2015; 5: 10382. Published online 2015 Aug 28. doi: 10.1038/srep10382
PMCID:
PMC4551968
AbstractArticlePDF–710K
3.
Dominant Negative Effects of Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL) Receptor 4 on TRAIL Receptor 1 Signaling by Formation of Heteromeric Complexes
Simon Neumann, Jan Hasenauer, Nadine Pollak, Peter Scheurich
J Biol Chem. 2014 Jun 6; 289(23): 16576–16587. Published online 2014 Apr 24. doi: 10.1074/jbc.M114.559468
PMCID:
PMC4047423
AbstractArticlePDF–1.9M
4.
Death Receptor (DR4) Haplotypes Are Associated with Increased Susceptibility of Gallbladder Carcinoma in North Indian Population
Rajani Rai, Kiran L. Sharma, Surbhi Sharma, Sanjeev Misra, Ashok Kumar, Balraj Mittal
PLoS One. 2014; 9(2): e90264. Published online 2014 Feb 28. doi: 10.1371/journal.pone.0090264
PMCID:
PMC3938657
AbstractArticlePDF–182K
5.
Constitutive localization of DR4 in lipid rafts is mandatory for TRAIL-induced apoptosis in B-cell hematologic malignancies
M Marconi, B Ascione, L Ciarlo, R Vona, T Garofalo, M Sorice, A M Gianni, S L Locatelli, C Carlo-Stella, W Malorni, P Matarrese
Cell Death Dis. 2013 Oct; 4(10): e863. Published online 2013 Oct 17. doi: 10.1038/cddis.2013.389
PMCID:
PMC3920963
AbstractArticlePDF–2.4M
6.
TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients
Christian Körner, Katarina Riesner, Benjamin Krämer, Marianne Eisenhardt, Andreas Glässner, Franziska Wolter, Thomas Berg, Tobias Müller, Tilman Sauerbruch, Jacob Nattermann, Ulrich Spengler, Hans Dieter Nischalke
BMC Cancer. 2012; 12: 85. Published online 2012 Mar 8. doi: 10.1186/1471-2407-12-85
PMCID:
PMC3372437
AbstractArticlePDF–369K
7.
Nitrosylcobalamin Promotes Cell Death via S Nitrosylation of Apo2L/TRAIL Receptor DR4
Zhuo Tang, Joseph A. Bauer, Bei Morrison, Daniel J. Lindner
Mol Cell Biol. 2006 Aug; 26(15): 5588–5594. doi: 10.1128/MCB.00199-06
PMCID:
PMC1592761
AbstractArticlePDF–466K
8.
Increased Expression of Death Receptors 4 and 5 Synergizes the Apoptosis Response to Combined Treatment with Etoposide and TRAIL
Spencer B. Gibson, Ryan Oyer, Aaron C. Spalding, Steven M. Anderson, Gary L. Johnson
Mol Cell Biol. 2000 Jan; 20(1): 205–212. doi: 10.1128/mcb.20.1.205-212.2000
PMCID:
PMC85076
AbstractArticlePDF–762K
9.
Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization
Joshua D Greenlee, Maria Lopez-Cavestany, Nerymar Ortiz-Otero, Kevin Liu, Tejas Subramanian, Burt Cagir, Michael R King
eLife. 2021; 10: e67750. Published online 2021 Aug 3. doi: 10.7554/eLife.67750
PMCID:
PMC8331188
AbstractArticlePDF–6.3M
10.
Epigenetic Modification of Death Receptor Genes for TRAIL and TRAIL Resistance in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia
Atsushi Watanabe, Kunio Miyake, Koshi Akahane, Kumiko Goi, Keiko Kagami, Hideo Yagita, Takeshi Inukai
Genes (Basel) 2021 Jun; 12(6): 864. Published online 2021 Jun 5. doi: 10.3390/genes12060864
PMCID:
PMC8229974
AbstractArticlePDF–4.1M
11.
Downregulation of death receptor 4 is tightly associated with positive response of EGFR mutant lung cancer to EGFR-targeted therapy and improved prognosis
Shuo Zhang, Zhen Chen, Puyu Shi, Songqing Fan, Yong He, Qiming Wang, Yixiang Li, Suresh S. Ramalingam, Taofeek K. Owonikoko, Shi-Yong Sun
Theranostics. 2021; 11(8): 3964–3980. Published online 2021 Feb 15. doi: 10.7150/thno.54824
PMCID:
PMC7914351
AbstractArticlePDF–3.6M
12.
Secretory stressors induce intracellular death receptor accumulation to control apoptosis
Bram J van Raam, Tamara Lacina, Ralph K Lindemann, Jan H Reiling
Cell Death Dis. 2017 Oct; 8(10): e3069. Published online 2017 Oct 5. doi: 10.1038/cddis.2017.466
PMCID:
PMC5680588
AbstractArticlePDF–3.3M
13.
TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress
Florent Dufour, Thibault Rattier, Andrei Alexandru Constantinescu, Luciana Zischler, Aymeric Morlé, Hazem Ben Mabrouk, Etienne Humblin, Guillaume Jacquemin, Eva Szegezdi, Fabien Delacote, Naziha Marrakchi, Gilles Guichard, Catherine Pellat-Deceunynck, Pierre Vacher, Patrick Legembre, Carmen Garrido, Olivier Micheau
Oncotarget. 2017 Feb 7; 8(6): 9974–9985. Published online 2016 Dec 27. doi: 10.18632/oncotarget.14285
PMCID:
PMC5354785
AbstractArticlePDF–5.2M
14.
Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition
Weilong Yao, You-Take Oh, Jiusheng Deng, Ping Yue, Liang Deng, Henry Huang, Wei Zhou, Shi-Yong Sun
J Biol Chem. 2016 Oct 7; 291(41): 21694–21702. Published online 2016 Aug 30. doi: 10.1074/jbc.M116.738302
Correction in:
J Biol Chem. 2020 Jun 26; 295(26): 8871.
PMCID:
PMC5076838
AbstractArticlePDF–1.7M
15.
TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill
Andrea Mohr, Rui Yu, Ralf M. Zwacka
BMC Cancer. 2015; 15: 494. Published online 2015 Jul 3. doi: 10.1186/s12885-015-1508-2
PMCID:
PMC4489125
AbstractArticlePDF–1.8M
16.
Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells
Youhong Liu, Lin Chen, Zhicheng Gong, Liangfang Shen, Chinghai Kao, Janet M. Hock, Lunquan Sun, Xiong Li
Oncotarget. 2015 Feb; 6(5): 3055–3070. Published online 2014 Dec 26. doi: 10.18632/oncotarget.3073
PMCID:
PMC4413637
AbstractArticlePDF–2.0M
17.
TRAIL-R1 Is a Negative Regulator of Pro-Inflammatory Responses and Modulates Long-Term Sequelae Resulting from Chlamydia trachomatis Infections in Humans
Mufadhal Al-Kuhlani, James Rothchild, Sukumar Pal, Luis M. de la Maza, Sander Ouburg, Servaas A. Morré, Deborah Dean, David M. Ojcius
PLoS One. 2014; 9(4): e93939. Published online 2014 Apr 2. doi: 10.1371/journal.pone.0093939
Correction in:
PLoS One. 2014; 9(8): e106964.
PMCID:
PMC3973638
AbstractArticlePDF–811K
18.
Human Embryonic and Induced Pluripotent Stem Cells Express TRAIL Receptors and Can Be Sensitized to TRAIL-Induced Apoptosis
Vladimir Vinarsky, Jan Krivanek, Liina Rankel, Zuzana Nahacka, Tomas Barta, Josef Jaros, Ladislav Andera, Ales Hampl
Stem Cells Dev. 2013 Nov 15; 22(22): 2964–2974. Published online 2013 Jun 27. doi: 10.1089/scd.2013.0057
PMCID:
PMC3822377
AbstractArticlePDF–734K
19.
Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL
Dolly G. Aguilera, Chandra M. Das, Neeta D. Sinnappah-Kang, Celine Joyce, Pete H. Taylor, Sijin Wen, Martin Hasselblatt, Werner Paulus, Greg Fuller, Johannes E. Wolff, Vidya Gopalakrishnan
J Neurooncol. Author manuscript; available in PMC 2013 Nov 7.
Published in final edited form as: J Neurooncol. 2009 Jul; 93(3): 10.1007/s11060-008-9788-x. Published online 2009 Jan 16. doi: 10.1007/s11060-008-9788-x
PMCID:
PMC3820292
AbstractArticlePDF–4.3M
20.
Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors
T Bagci-Onder, A Agarwal, D Flusberg, S Wanningen, P Sorger, K Shah
Oncogene. Author manuscript; available in PMC 2014 Jun 6.
Published in final edited form as: Oncogene. 2013 Jun 6; 32(23): 2818–2827. Published online 2012 Jul 23. doi: 10.1038/onc.2012.304
PMCID:
PMC3676868
AbstractArticlePDF–3.2M

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