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1.
Expression and functional characterization of INPP4B in gallbladder cancer patients and gallbladder cancer cells
Youliang Wu, Delong Meng, Xin Xu, Junjun Bao, Yexiang You, Yanjun Sun, Yongxiang Li, Dengqun Sun
BMC Cancer. 2021; 21: 433. Published online 2021 Apr 20. doi: 10.1186/s12885-021-08143-6
PMCID:
PMC8056679
AbstractArticlePDF–7.8M
2.
Estrogen receptor β regulates AKT activity through up-regulation of INPP4B and inhibits migration of prostate cancer cell line PC-3
Surendra Chaurasiya, Wanfu Wu, Anders M. Strom, Margaret Warner, Jan-Åke Gustafsson
Proc Natl Acad Sci U S A. 2020 Oct 20; 117(42): 26347–26355. Published online 2020 Oct 5. doi: 10.1073/pnas.2007160117
PMCID:
PMC7584887
AbstractArticlePDF–2.5M
3.
INPP4B restrains cell proliferation and metastasis via regulation of the PI3K/AKT/SGK pathway
Ying Chen, Zeyu Sun, Mei Qi, Xiao Wang, Weifang Zhang, Chunyan Chen, Juan Liu, Weiming Zhao
J Cell Mol Med. 2018 May; 22(5): 2935–2943. Published online 2018 Mar 7. doi: 10.1111/jcmm.13595
PMCID:
PMC5908107
AbstractArticlePDF–1.4M
4.
INPP4B is an oncogenic regulator in human colon cancer
S T Guo, M N Chi, R H Yang, X Y Guo, L K Zan, C Y Wang, Y F Xi, L Jin, A Croft, H-Y Tseng, X G Yan, M Farrelly, F H Wang, F Lai, J F Wang, Y P Li, S Ackland, R Scott, I U Agoulnik, H Hondermarck, R F Thorne, T Liu, X D Zhang, C C Jiang
Oncogene. 2016 Jun 9; 35(23): 3049–3061. Published online 2015 Sep 28. doi: 10.1038/onc.2015.361
PMCID:
PMC4908438
AbstractArticlePDF–4.2M
5.
Endosome and INPP4B
Chen Li Chew, Ming Chen, Pier Paolo Pandolfi
Oncotarget. 2016 Jan 5; 7(1): 5–6. Published online 2015 Dec 18. doi: 10.18632/oncotarget.6663
PMCID:
PMC4807978
ArticlePDF–673K
6.
Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities
Sandra M. Lopez, Myles C. Hodgson, Charles Packianathan, Ozlem Bingol-Ozakpinar, Fikriye Uras, Barry P. Rosen, Irina U. Agoulnik
Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Sep 22.
Published in final edited form as: Biochem Biophys Res Commun. 2013 Oct 18; 440(2): 277–282. Published online 2013 Sep 23. doi: 10.1016/j.bbrc.2013.09.077
PMCID:
PMC4578723
AbstractArticlePDF–598K
7.
Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment
Laura R. H. Ip, George Poulogiannis, Felipe Cia Viciano, Junko Sasaki, Satoshi Kofuji, Victoria J. Spanswick, Daniel Hochhauser, John A. Hartley, Takehiko Sasaki, Christina A. Gewinner
Oncotarget. 2015 Apr 30; 6(12): 10548–10562. Published online 2015 Mar 24. doi: 10.18632/oncotarget.3307
PMCID:
PMC4496374
AbstractArticlePDF–3.3M
8.
Epigenetic Inactivation of Inositol polyphosphate 4-phosphatase B (INPP4B), a Regulator of PI3K/AKT Signaling Pathway in EBV-Associated Nasopharyngeal Carcinoma
Jessie Wai-Fong Yuen, Grace Tin-Yun Chung, Samantha Wei-Man Lun, Chartia Ching-Mei Cheung, Ka-Fai To, Kwok-Wai Lo
PLoS One. 2014; 9(8): e105163. Published online 2014 Aug 15. doi: 10.1371/journal.pone.0105163
PMCID:
PMC4134277
AbstractArticlePDF–1.0M
9.
Identification of inositol polyphosphate 4-phosphatase type II as a novel tumor resistance biomarker in human laryngeal cancer HEp-2 cells
Jae-Sung Kim, Hong Shik Yun, Hong-Duck Um, Jong Kuk Park, Kee-Ho Lee, Chang-Mo Kang, Su-Jae Lee, Sang-Gu Hwang
Cancer Biol Ther. 2012 Nov 1; 13(13): 1307–1318. doi: 10.4161/cbt.21788
PMCID:
PMC3493439
AbstractArticlePDF–1.5M
10.
INPP4B: the New Kid on the PI3K Block
Irina U. Agoulnik, Myles C. Hodgson, Wayne A. Bowden, Michael M. Ittmann
Oncotarget. 2011 Apr; 2(4): 321–328. Published online 2011 Apr 10. doi: 10.18632/oncotarget.260
PMCID:
PMC3248162
AbstractArticlePDF–1.0M
11.
Evidence that Inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling
Christina Gewinner, Zhigang C. Wang, Andrea Richardson, Julie Teruya-Feldstein, Dariush Etemadmoghadam, David Bowtell, Jordi Barretina, William M Lin, Lucia Rameh, Leonardo Salmena, Pier Paolo Pandolfi, Lewis C. Cantley
Cancer Cell. Author manuscript; available in PMC 2010 Oct 19.
Published in final edited form as: Cancer Cell. 2009 Aug 4; 16(2): 115–125. doi: 10.1016/j.ccr.2009.06.006
PMCID:
PMC2957372
AbstractArticlePDF–2.1M
12.
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer
Samuel J. Rodgers, Lisa M. Ooms, Viola M. J. Oorschot, Ralf B. Schittenhelm, Elizabeth V. Nguyen, Sabryn A. Hamila, Natalie Rynkiewicz, Rajendra Gurung, Matthew J. Eramo, Absorn Sriratana, Clare G. Fedele, Franco Caramia, Sherene Loi, Genevieve Kerr, Helen E. Abud, Georg Ramm, Antonella Papa, Andrew M. Ellisdon, Roger J. Daly, Catriona A. McLean, Christina A. Mitchell
Nat Commun. 2021; 12: 3140. Published online 2021 May 25. doi: 10.1038/s41467-021-23241-6
PMCID:
PMC8149851
AbstractArticlePDF–4.2M
13.
miR-1290 Contributes to Colorectal Cancer Cell Proliferation by Targeting INPP4B
Qingzhu Ma, Yan Wang, Hualing Zhang, Fengqiang Wang
Oncol Res. 2018; 26(8): 1167–1174. Published online 2018 Sep 14. doi: 10.3727/096504017X15051741798389
PMCID:
PMC7844673
AbstractArticlePDF–7.7M
14.
Genetic interactions between INPP4B and RAD50 is prognostic of breast cancer survival
Xiao Chen, Rutaganda Theobard, Jianying Zhang, Xiaofeng Dai
Biosci Rep. 2020 Jan 31; 40(1): BSR20192546. Published online 2020 Jan 10. doi: 10.1042/BSR20192546
PMCID:
PMC6954369
AbstractArticlePDF–1.5M
15.
SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML
Irakli Dzneladze, John F. Woolley, Carla Rossell, Youqi Han, Ayesha Rashid, Michael Jain, Jüri Reimand, Mark D. Minden, Leonardo Salmena
PLoS One. 2018; 13(2): e0191510. Published online 2018 Feb 7. doi: 10.1371/journal.pone.0191510
Correction in:
PLoS One. 2018; 13(3): e0195417.
PMCID:
PMC5802890
AbstractArticlePDF–9.5M
16.
INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas
Meng Na Chi, Su Tang Guo, James S. Wilmott, Xiang Yun Guo, Xu Guang Yan, Chun Yan Wang, Xiao Ying Liu, Lei Jin, Hsin-Yi Tseng, Tao Liu, Amanda Croft, Hubert Hondermarck, Richard A. Scolyer, Chen Chen Jiang, Xu Dong Zhang
Oncotarget. 2015 Nov 24; 6(37): 39891–39907. Published online 2015 Nov 9. doi: 10.18632/oncotarget.5359
PMCID:
PMC4741868
AbstractArticlePDF–4.4M
17.
INPP4B suppresses prostate cancer cell invasion
Myles C Hodgson, Elena I Deryugina, Egla Suarez, Sandra M Lopez, Dong Lin, Hui Xue, Ivan P Gorlov, Yuzhuo Wang, Irina U Agoulnik
Cell Commun Signal. 2014; 12: 61. Published online 2014 Sep 25. doi: 10.1186/s12964-014-0061-y
PMCID:
PMC4181726
AbstractArticlePDF–3.1M
18.
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers
Clare G. Fedele, Lisa M. Ooms, Miriel Ho, Jessica Vieusseux, Sandra A. O'Toole, Ewan K. Millar, Elena Lopez-Knowles, Absorn Sriratana, Rajendra Gurung, Laura Baglietto, Graham G. Giles, Charles G. Bailey, John E. J. Rasko, Benjamin J. Shields, John T. Price, Philip W. Majerus, Robert L. Sutherland, Tony Tiganis, Catriona A. McLean, Christina A. Mitchell
Proc Natl Acad Sci U S A. 2010 Dec 21; 107(51): 22231–22236. Published online 2010 Dec 2. doi: 10.1073/pnas.1015245107
PMCID:
PMC3009830
AbstractArticlePDF–1.0M
19.
TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K–C2α-, and INPP4B-mediated phosphoinositide conversions
Sho Aki, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa
Mol Biol Cell. 2020 Mar 1; 31(5): 360–372. doi: 10.1091/mbc.E19-11-0662
PMCID:
PMC7183790
AbstractArticlePDF–3.6M
20.
INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia
Hongjun Jin, Liyuan Yang, Lu Wang, Zailin Yang, Qian Zhan, Yao Tao, Qin Zou, Yuting Tang, Jingrong Xian, Shuaishuai Zhang, Yipei Jing, Ling Zhang
J Exp Clin Cancer Res. 2018; 37: 8. Published online 2018 Jan 17. doi: 10.1186/s13046-018-0675-9
PMCID:
PMC5773044
AbstractArticlePDF–2.8M

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