PMC Links for Gene (Select 8843) - PMC

Select item 34028021.

Activated human hydroxy-carboxylic acid receptor-3 signals to MAP kinase cascades via the PLC-dependent PKC and MMP-mediated EGFR pathways

Q Zhou, G Li, XY Deng, XB He, LJ Chen, C Wu, Y Shi, KP Wu, LJ Mei, JX Lu, NM Zhou

Br J Pharmacol. 2012 Jul; 166(6): 1756–1773. doi: 10.1111/j.1476-5381.2012.01875.x

PMCID:: PMC3402802

Abstract Article PDF–3.2M

Select item 26561822.

Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B

Yoko Irukayama-Tomobe, Hirokazu Tanaka, Takehiko Yokomizo, Tomomi Hashidate-Yoshida, Masashi Yanagisawa, Takeshi Sakurai

Proc Natl Acad Sci U S A. 2009 Mar 10; 106(10): 3930–3934. Published online 2009 Feb 23. doi: 10.1073/pnas.0811844106

PMCID:: PMC2656182

Abstract Article PDF–620K

Select item 87052443.

Alterations in Kynurenine and NAD⁺ Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets

Artur Wnorowski, Sylwia Wnorowska, Jacek Kurzepa, Jolanta Parada-Turska

Int J Mol Sci. 2021 Dec; 22(24): 13497. Published online 2021 Dec 16. doi: 10.3390/ijms222413497

PMCID:: PMC8705244

Abstract Article PDF–2.2M

Select item 70454124.

Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84

Anna Peters, Philipp Rabe, Petra Krumbholz, Hermann Kalwa, Robert Kraft, Torsten Schöneberg, Claudia Stäubert

Cell Commun Signal. 2020; 18: 31. Published online 2020 Feb 26. doi: 10.1186/s12964-020-0516-2

PMCID:: PMC7045412

Abstract Article PDF–6.7M

Select item 46373155.

Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism

Claudia Stäubert, Oliver Jay Broom, Anders Nordström

Oncotarget. 2015 Aug 14; 6(23): 19706–19720. Published online 2015 Mar 14. doi: 10.18632/oncotarget.3565

PMCID:: PMC4637315

Abstract Article PDF–4.6M

Select item 31050696.

Nicotinic Acid Receptor Abnormalities in Human Skin Cancer: Implications for a Role in Epidermal Differentiation

Yira Bermudez, Claudia A. Benavente, Ralph G. Meyer, W. Russell Coyle, Myron K. Jacobson, Elaine L. Jacobson

PLoS One. 2011; 6(5): e20487. Published online 2011 May 31. doi: 10.1371/journal.pone.0020487

PMCID:: PMC3105069

Abstract Article PDF–2.5M

Select item 27559177.

Deorphanization of GPR109B as a Receptor for the β-Oxidation Intermediate 3-OH-octanoic Acid and Its Role in the Regulation of Lipolysis

Kashan Ahmed, Sorin Tunaru, Claus-Dieter Langhans, Julien Hanson, Christoph W. Michalski, Stefan Kölker, Patricia M. Jones, Jürgen G. Okun, Stefan Offermanns

J Biol Chem. 2009 Aug 14; 284(33): 21928–21933. Published online 2009 Jun 26. doi: 10.1074/jbc.M109.019455

PMCID:: PMC2755917

Abstract Article PDF–974K

Select item 86381848.

Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases

Cierla McGuire Sams, Kasey Shepp, Jada Pugh, Madison R. Bishop, Nancy D. Merner

BMC Med Genomics. 2021; 14: 284. Published online 2021 Dec 1. doi: 10.1186/s12920-021-01126-3

PMCID:: PMC8638184

Abstract Article PDF–4.5M

Select item 28556879.

Two Complex Genotypes Relevant to the Kynurenine Pathway and Melanotropin Function show Association with Schizophrenia and Bipolar Disorder

Christine L. Miller, Peter Murakami, Ingo Ruczinski, Randal G. Ross, Melissa Sinkus, Bernadette Sullivan, Sherry Leonard

Schizophr Res. Author manuscript; available in PMC 2010 Apr 16.

Published in final edited form as: Schizophr Res. 2009 Sep; 113(2-3): 259–267. Published online 2009 Jun 6. doi: 10.1016/j.schres.2009.05.014

PMCID:: PMC2855687

Abstract Article PDF–1.1M

Select item 278532610.

Peroxisome Proliferator-activated Receptor γ Regulates Expression of the Anti-lipolytic G-protein-coupled Receptor 81 (GPR81/Gpr81)

Ellen H. Jeninga, Anne Bugge, Ronni Nielsen, Sander Kersten, Nicole Hamers, Christian Dani, Martin Wabitsch, Ruud Berger, Hendrik G. Stunnenberg, Susanne Mandrup, Eric Kalkhoven

J Biol Chem. 2009 Sep 25; 284(39): 26385–26393. Published online 2009 Jul 24. doi: 10.1074/jbc.M109.040741

PMCID:: PMC2785326

Abstract Article PDF–1.2M

Select item 239476011.

Large-scale identification of human genes implicated in epidermal barrier function

Eve Toulza, Nicolas R Mattiuzzo, Marie-Florence Galliano, Nathalie Jonca, Carole Dossat, Daniel Jacob, Antoine de Daruvar, Patrick Wincker, Guy Serre, Marina Guerrin

Genome Biol. 2007; 8(6): R107. Published online 2007 Jun 11. doi: 10.1186/gb-2007-8-6-r107

PMCID:: PMC2394760

Abstract Article PDF–1.0M

Select item 274057212.

A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication

Man Lung Yeung, Laurent Houzet, Venkat S. R. K. Yedavalli, Kuan-Teh Jeang

J Biol Chem. 2009 Jul 17; 284(29): 19463–19473. Published online 2009 May 20. doi: 10.1074/jbc.M109.010033

PMCID:: PMC2740572

Abstract Article PDF–2.5M

Select item 294516813.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 277583214.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

Select item 135612915.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406