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Select item 86047281.

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

Qiufeng Liu, Dehua Yang, Youwen Zhuang, Tristan I. Croll, Xiaoqing Cai, Antao Dai, Xinheng He, Jia Duan, Wanchao Yin, Chenyu Ye, Fulai Zhou, Beili Wu, Qiang Zhao, H. Eric Xu, Ming-Wei Wang, Yi Jiang

Nat Chem Biol. 2021; 17(12): 1238–1244. Published online 2021 Sep 23. doi: 10.1038/s41589-021-00841-3

PMCID:: PMC8604728

Abstract Article PDF–6.2M

Select item 76015272.

Photodynamic Activation of Cholecystokinin 1 Receptor with Different Genetically Encoded Protein Photosensitizers and from Varied Subcellular Sites

Yuan Li, Zong Jie Cui

Biomolecules. 2020 Oct; 10(10): 1423. Published online 2020 Oct 8. doi: 10.3390/biom10101423

PMCID:: PMC7601527

Abstract Article PDF–2.3M

Select item 43059543.

Gallbladder motor function, plasma cholecystokinin and cholecystokinin receptor of gallbladder in cholesterol stone patients

Jian Zhu, Tian-Quan Han, Sheng Chen, Yu Jiang, Sheng-Dao Zhang

World J Gastroenterol. 2005 Mar 21; 11(11): 1685–1689. Published online 2005 Mar 21. doi: 10.3748/wjg.v11.i11.1685

PMCID:: PMC4305954

Abstract Article PDF–335K

Select item 41402874.

A Type 1 Cholecystokinin Receptor Mutant That Mimics the Dysfunction Observed for Wild Type Receptor in a High Cholesterol Environment

Aditya J. Desai, Kaleeckal G. Harikumar, Laurence J. Miller

J Biol Chem. 2014 Jun 27; 289(26): 18314–18326. Published online 2014 May 13. doi: 10.1074/jbc.M114.570200

PMCID:: PMC4140287

Abstract Article PDF–2.2M

Select item 40828615.

Differential Expression of Cholecystokinin A Receptor in Gallbladder Cancer in the Young and Elderly Suggests Two Subsets of the Same Disease?

Hasan Raza Kazmi, Abhijit Chandra, Kavita Baghel, Anshuman Singh, Jaya Nigam, Devendra Parmar, Abbas Ali Mahdi, Sudhir K. Goel, Sandeep Kumar

Biomed Res Int. 2014; 2014: 625695. Published online 2014 Jun 15. doi: 10.1155/2014/625695

PMCID:: PMC4082861

Abstract Article PDF–749K

Select item 38205826.

Variants in CCK and CCKAR genes to susceptibility to biliary tract cancers and stones: a population-based study in Shanghai, China

Hong-Li Xu, Ann W. Hsing, Emily Vogtmann, Lisa W. Chu, Jia-Rong Cheng, Jing Gao, Yu-Ting Tan, Bing-Sheng Wang, Ming-Chang Shen, Yu-Tang Gao

J Gastroenterol Hepatol. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Gastroenterol Hepatol. 2013 Sep; 28(9): 10.1111/jgh.12278. doi: 10.1111/jgh.12278

PMCID:: PMC3820582

Abstract Article PDF–56K

Select item 35449207.

Cholecystokinin A Receptor (CCKAR) Gene Variation Is Associated with Language Lateralization

Sebastian Ocklenburg, Larissa Arning, Wanda M. Gerding, Jörg T. Epplen, Onur Güntürkün, Christian Beste

PLoS One. 2013; 8(1): e53643. Published online 2013 Jan 14. doi: 10.1371/journal.pone.0053643

PMCID:: PMC3544920

Abstract Article PDF–153K

Select item 32434708.

Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol

Ross M. Potter, Kaleeckal G. Harikumar, S.Vincent Wu, Laurence J. Miller

J Lipid Res. 2012 Jan; 53(1): 137–148. doi: 10.1194/jlr.M020065

PMCID:: PMC3243470

Abstract Article PDF–944K

Select item 28798319.

Association of CCK₁ Receptor Gene Polymorphisms and Irritable Bowel Syndrome in Korean

Seon-Young Park, Jong-Sun Rew, Soo-Mi Lee, Ho-Seok Ki, Kyong-Rok Lee, Jun-Ho Cheo, Hyung-Il Kim, Du-Yeong Noh, Young-Eun Joo, Hyun-Soo Kim, Sung-Kyu Choi

J Neurogastroenterol Motil. 2010 Jan; 16(1): 71–76. Published online 2010 Jan 31. doi: 10.5056/jnm.2010.16.1.71

PMCID:: PMC2879831

Abstract Article PDF–226K

Select item 1129085310.

Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling

Kaleeckal G. Harikumar, Peishen Zhao, Brian P. Cary, Xiaomeng Xu, Aditya J. Desai, Maoqing Dong, Jesse I. Mobbs, Chirine Toufaily, Sebastian G. B. Furness, Arthur Christopoulos, Matthew J. Belousoff, Denise Wootten, Patrick M. Sexton, Laurence J. Miller

PLoS Biol. 2024 Jul; 22(7): e3002673. Published online 2024 Jul 31. doi: 10.1371/journal.pbio.3002673

PMCID:: PMC11290853

Abstract Article PDF–3.4M

Select item 472790011.

Variants near CCK receptors are associated with electrophysiological responses to prepulse startle stimuli in a Mexican American cohort

Trina M. Norden-Krichmar, Ian R. Gizer, Evelyn Phillips, Kirk C. Wilhelmsen, Nicholas J. Schork, Cindy L. Ehlers

Twin Res Hum Genet. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Twin Res Hum Genet. 2015 Dec; 18(6): 727–737. Published online 2015 Nov 26. doi: 10.1017/thg.2015.77

PMCID:: PMC4727900

Abstract Article PDF–912K

Select item 404734112.

Investigation of cholecystokinin receptors in the human lower esophageal sphincter

Jun-Feng Liu, Jian Zhang, Xin-Bo Liu, Paul A Drew

World J Gastroenterol. 2014 Jun 7; 20(21): 6554–6559. Published online 2014 Jun 7. doi: 10.3748/wjg.v20.i21.6554

PMCID:: PMC4047341

Abstract Article PDF–1.0M

Select item 295069413.

Effects of cholesterol on CCK-1 receptors and caveolin-3 proteins recycling in human gallbladder muscle

P. Cong, V. Pricolo, P. Biancani, J. Behar

Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3): G742–G750. Published online 2010 Jun 17. doi: 10.1152/ajpgi.00064.2010

PMCID:: PMC2950694

Abstract Article

Select item 214418514.

Arginine 197 of the cholecystokinin-A receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin.

V. Gigoux, B. Maigret, C. Escrieut, S. Silvente-Poirot, M. Bouisson, J. A. Fehrentz, L. Moroder, D. Gully, J. Martinez, N. Vaysse, A. D. Fourmy

Protein Sci. 1999 Nov; 8(11): 2347–2354. doi: 10.1110/ps.8.11.2347

PMCID:: PMC2144185

Summary PDF–637K

Select item 157490915.

Involvement of endogenous CCK and CCK₁ receptors in colonic motor function

Gábor Varga, András Bálint, Beáta Burghardt, Massimo D'Amato

Br J Pharmacol. 2004 Apr; 141(8): 1275–1284. Published online 2004 Apr 22. doi: 10.1038/sj.bjp.0705769

PMCID:: PMC1574909

Abstract Article PDF–295K

Select item 820856916.

Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity

Jesse I. Mobbs, Matthew J. Belousoff, Kaleeckal G. Harikumar, Sarah J. Piper, Xiaomeng Xu, Sebastian G. B. Furness, Hari Venugopal, Arthur Christopoulos, Radostin Danev, Denise Wootten, David M. Thal, Laurence J. Miller, Patrick M. Sexton

PLoS Biol. 2021 Jun; 19(6): e3001295. Published online 2021 Jun 4. doi: 10.1371/journal.pbio.3001295