PMC Links for Gene (Select 89822) - PMC

Select item 41193561.

Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder

Corinna Friedrich, Susanne Rinné, Sven Zumhagen, Aytug K Kiper, Nicole Silbernagel, Michael F Netter, Birgit Stallmeyer, Eric Schulze-Bahr, Niels Decher

EMBO Mol Med. 2014 Jul; 6(7): 937–951. Published online 2014 Jun 27. doi: 10.15252/emmm.201303783

PMCID:: PMC4119356

Abstract Article PDF–2.1M

Select item 58248532.

Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity

Sam Chai, Xiaoping Wan, Angelina Ramirez-Navarro, Paul J. Tesar, Elizabeth S. Kaufman, Eckhard Ficker, Alfred L. George, Jr., Isabelle Deschênes

J Clin Invest. 2018 Mar 1; 128(3): 1043–1056. Published online 2018 Feb 12. doi: 10.1172/JCI94996

PMCID:: PMC5824853

Abstract Article PDF–3.8M

Select item 56346293.

Heterodimerization of two pore domain K⁺ channel TASK1 and TALK2 in living heterologous expression systems

Yoshiaki Suzuki, Kanako Tsutsumi, Tatsuya Miyamoto, Hisao Yamamura, Yuji Imaizumi

PLoS One. 2017; 12(10): e0186252. Published online 2017 Oct 10. doi: 10.1371/journal.pone.0186252

PMCID:: PMC5634629

Abstract Article PDF–2.3M

Select item 25184624.

Regulation of two-pore-domain (K_2P) potassium leak channels by the tyrosine kinase inhibitor genistein

J Gierten, E Ficker, R Bloehs, K Schlömer, S Kathöfer, E Scholz, E Zitron, C Kiesecker, A Bauer, R Becker, H A Katus, C A Karle, D Thomas

Br J Pharmacol. 2008 Aug; 154(8): 1680–1690. Published online 2008 Jun 2. doi: 10.1038/bjp.2008.213

PMCID:: PMC2518462

Abstract Article PDF–347K

Select item 35823985.

Meta-analysis of genome-wide association studies identifies 8 new loci for type 2 diabetes in East Asians

Yoon Shin Cho, Chien-Hsiun Chen, Cheng Hu, Jirong Long, Rick Twee Hee Ong, Xueling Sim, Fumihiko Takeuchi, Ying Wu, Min Jin Go, Toshimasa Yamauchi, Yi-Cheng Chang, Soo Heon Kwak, Ronald C.W. Ma, Ken Yamamoto, Linda S. Adair, Tin Aung, Qiuyin Cai, Li-Ching Chang, Yuan-Tsong Chen, Yutang Gao, Frank B. Hu, Hyung-Lae Kim, Sangsoo Kim, Young Jin Kim, Jeannette Jen-Mai Lee, Nanette R. Lee, Yun Li, Jian Jun Liu, Wei Lu, Jiro Nakamura, Eitaro Nakashima, Daniel Peng-Keat Ng, Wan Ting Tay, Fuu-Jen Tsai, Tien Yin Wong, Mitsuhiro Yokota, Wei Zheng, Rong Zhang, Congrong Wang, Wing Yee So, Keizo Ohnaka, Hiroshi Ikegami, Kazuo Hara, Young Min Cho, Nam H Cho, Tien-Jyun Chang, Yuqian Bao, Åsa K. Hedman, Andrew P. Morris, Mark I. McCarthy, DIAGRAM consortium, MuTHER consortium, Ryoichi Takayanagi, Kyong Soo Park, Weiping Jia, Lee-Ming Chuang, Juliana C.N. Chan, Shiro Maeda, Takashi Kadowaki, Jong-Young Lee, Jer-Yuarn Wu, Yik Ying Teo, E Shyong Tai, Xiao Ou Shu, Karen L. Mohlke, Norihiro Kato, Bok-Ghee Han, Mark Seielstad

Nat Genet. Author manuscript; available in PMC 2013 Feb 26.

Published in final edited form as: Nat Genet. 2011 Dec 11; 44(1): 67–72. Published online 2011 Dec 11. doi: 10.1038/ng.1019

PMCID:: PMC3582398

Abstract Article PDF–2.4M

Select item 39696126.

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium

Nat Genet. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Nat Genet. 2014 Mar; 46(3): 234–244. Published online 2014 Feb 9. doi: 10.1038/ng.2897

PMCID:: PMC3969612

Abstract Article PDF–725K

Select item 38386667.

Discovery and Refinement of Loci Associated with Lipid Levels

Cristen J. Willer, Ellen M. Schmidt, Sebanti Sengupta, Gina M. Peloso, Stefan Gustafsson, Stavroula Kanoni, Andrea Ganna, Jin Chen, Martin L. Buchkovich, Samia Mora, Jacques S. Beckmann, Jennifer L. Bragg-Gresham, Hsing-Yi Chang, Ayse Demirkan, Heleen M. Den Hertog, Ron Do, Louise A. Donnelly, Georg B. Ehret, Tõnu Esko, Mary F. Feitosa, Teresa Ferreira, Krista Fischer, Pierre Fontanillas, Ross M. Fraser, Daniel F. Freitag, Deepti Gurdasani, Kauko Heikkilä, Elina Hyppönen, Aaron Isaacs, Anne U. Jackson, Åsa Johansson, Toby Johnson, Marika Kaakinen, Johannes Kettunen, Marcus E. Kleber, Xiaohui Li, Jian’an Luan, Leo-Pekka Lyytikäinen, Patrik K.E. Magnusson, Massimo Mangino, Evelin Mihailov, May E. Montasser, Martina Müller-Nurasyid, Ilja M. Nolte, Jeffrey R. O’Connell, Cameron D. Palmer, Markus Perola, Ann-Kristin Petersen, Serena Sanna, Richa Saxena, Susan K. Service, Sonia Shah, Dmitry Shungin, Carlo Sidore, Ci Song, Rona J. Strawbridge, Ida Surakka, Toshiko Tanaka, Tanya M. Teslovich, Gudmar Thorleifsson, Evita G. Van den Herik, Benjamin F. Voight, Kelly A. Volcik, Lindsay L. Waite, Andrew Wong, Ying Wu, Weihua Zhang, Devin Absher, Gershim Asiki, Inês Barroso, Latonya F. Been, Jennifer L. Bolton, Lori L Bonnycastle, Paolo Brambilla, Mary S. Burnett, Giancarlo Cesana, Maria Dimitriou, Alex S.F. Doney, Angela Döring, Paul Elliott, Stephen E. Epstein, Gudmundur Ingi Eyjolfsson, Bruna Gigante, Mark O. Goodarzi, Harald Grallert, Martha L. Gravito, Christopher J. Groves, Göran Hallmans, Anna-Liisa Hartikainen, Caroline Hayward, Dena Hernandez, Andrew A. Hicks, Hilma Holm, Yi-Jen Hung, Thomas Illig, Michelle R. Jones, Pontiano Kaleebu, John J.P. Kastelein, Kay-Tee Khaw, Eric Kim, Norman Klopp, Pirjo Komulainen, Meena Kumari, Claudia Langenberg, Terho Lehtimäki, Shih-Yi Lin, Jaana Lindström, Ruth J.F. Loos, François Mach, Wendy L McArdle, Christa Meisinger, Braxton D. Mitchell, Gabrielle Müller, Ramaiah Nagaraja, Narisu Narisu, Tuomo V.M. Nieminen, Rebecca N. Nsubuga, Isleifur Olafsson, Ken K. Ong, Aarno Palotie, Theodore Papamarkou, Cristina Pomilla, Anneli Pouta, Daniel J. Rader, Muredach P. Reilly, Paul M. Ridker, Fernando Rivadeneira, Igor Rudan, Aimo Ruokonen, Nilesh Samani, Hubert Scharnagl, Janet Seeley, Kaisa Silander, Alena Stancáková, Kathleen Stirrups, Amy J. Swift, Laurence Tiret, Andre G. Uitterlinden, L. Joost van Pelt, Sailaja Vedantam, Nicholas Wainwright, Cisca Wijmenga, Sarah H. Wild, Gonneke Willemsen, Tom Wilsgaard, James F. Wilson, Elizabeth H. Young, Jing Hua Zhao, Linda S. Adair, Dominique Arveiler, Themistocles L. Assimes, Stefania Bandinelli, Franklyn Bennett, Murielle Bochud, Bernhard O. Boehm, Dorret I. Boomsma, Ingrid B. Borecki, Stefan R. Bornstein, Pascal Bovet, Michel Burnier, Harry Campbell, Aravinda Chakravarti, John C. Chambers, Yii-Der Ida Chen, Francis S. Collins, Richard S. Cooper, John Danesh, George Dedoussis, Ulf de Faire, Alan B. Feranil, Jean Ferrières, Luigi Ferrucci, Nelson B. Freimer, Christian Gieger, Leif C. Groop, Vilmundur Gudnason, Ulf Gyllensten, Anders Hamsten, Tamara B. Harris, Aroon Hingorani, Joel N. Hirschhorn, Albert Hofman, G. Kees Hovingh, Chao Agnes Hsiung, Steve E. Humphries, Steven C. Hunt, Kristian Hveem, Carlos Iribarren, Marjo-Riitta Järvelin, Antti Jula, Mika Kähönen, Jaakko Kaprio, Antero Kesäniemi, Mika Kivimaki, Jaspal S. Kooner, Peter J. Koudstaal, Ronald M. Krauss, Diana Kuh, Johanna Kuusisto, Kirsten O. Kyvik, Markku Laakso, Timo A. Lakka, Lars Lind, Cecilia M. Lindgren, Nicholas G. Martin, Winfried März, Mark I. McCarthy, Colin A. McKenzie, Pierre Meneton, Andres Metspalu, Leena Moilanen, Andrew D. Morris, Patricia B. Munroe, Inger Njølstad, Nancy L. Pedersen, Chris Power, Peter P. Pramstaller, Jackie F. Price, Bruce M. Psaty, Thomas Quertermous, Rainer Rauramaa, Danish Saleheen, Veikko Salomaa, Dharambir K. Sanghera, Jouko Saramies, Peter E.H. Schwarz, Wayne H-H Sheu, Alan R. Shuldiner, Agneta Siegbahn, Tim D. Spector, Kari Stefansson, David P. Strachan, Bamidele O. Tayo, Elena Tremoli, Jaakko Tuomilehto, Matti Uusitupa, Cornelia M. van Duijn, Peter Vollenweider, Lars Wallentin, Nicholas J. Wareham, John B. Whitfield, Bruce H.R. Wolffenbuttel, Jose M. Ordovas, Eric Boerwinkle, Colin N.A. Palmer, Unnur Thorsteinsdottir, Daniel I. Chasman, Jerome I. Rotter, Paul W. Franks, Samuli Ripatti, L. Adrienne Cupples, Manjinder S. Sandhu, Stephen S. Rich, Michael Boehnke, Panos Deloukas, Sekar Kathiresan, Karen L. Mohlke, Erik Ingelsson, Gonçalo R. Abecasis, The Global Lipids Genetics Consortium

Nat Genet. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Nat Genet. 2013 Nov; 45(11): 1274–1283. Published online 2013 Oct 6. doi: 10.1038/ng.2797

PMCID:: PMC3838666

Abstract Article PDF–1.0M

Select item 4036978.

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanabe, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I. Wood, Paul Godowski

Genome Res. 2003 Oct; 13(10): 2265–2270. doi: 10.1101/gr.1293003