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Select item 38588281.

TBP-TAF Complex SL1 Directs RNA Polymerase I Pre-initiation Complex Formation and Stabilizes Upstream Binding Factor at the rDNA Promoter

J. Karsten Friedrich, Kostya I. Panov, Pavel Cabart, Jackie Russell, Joost C. B. M. Zomerdijk

J Biol Chem. Author manuscript; available in PMC 2013 Dec 11.

Published in final edited form as: J Biol Chem. 2005 Aug 19; 280(33): 10.1074/jbc.M501595200. Published online 2005 Jun 21. doi: 10.1074/jbc.M501595200

PMCID:: PMC3858828

Abstract Article PDF–1.8M

Select item 34713952.

Individual common variants exert weak effects on the risk for autism spectrum disorders

Richard Anney, Lambertus Klei, Dalila Pinto, Joana Almeida, Elena Bacchelli, Gillian Baird, Nadia Bolshakova, Sven Bölte, Patrick F. Bolton, Thomas Bourgeron, Sean Brennan, Jessica Brian, Jillian Casey, Judith Conroy, Catarina Correia, Christina Corsello, Emily L. Crawford, Maretha de Jonge, Richard Delorme, Eftichia Duketis, Frederico Duque, Annette Estes, Penny Farrar, Bridget A. Fernandez, Susan E. Folstein, Eric Fombonne, John Gilbert, Christopher Gillberg, Joseph T. Glessner, Andrew Green, Jonathan Green, Stephen J. Guter, Elizabeth A. Heron, Richard Holt, Jennifer L. Howe, Gillian Hughes, Vanessa Hus, Roberta Igliozzi, Suma Jacob, Graham P. Kenny, Cecilia Kim, Alexander Kolevzon, Vlad Kustanovich, Clara M. Lajonchere, Janine A. Lamb, Miriam Law-Smith, Marion Leboyer, Ann Le Couteur, Bennett L. Leventhal, Xiao-Qing Liu, Frances Lombard, Catherine Lord, Linda Lotspeich, Sabata C. Lund, Tiago R. Magalhaes, Carine Mantoulan, Christopher J. McDougle, Nadine M. Melhem, Alison Merikangas, Nancy J. Minshew, Ghazala K. Mirza, Jeff Munson, Carolyn Noakes, Gudrun Nygren, Katerina Papanikolaou, Alistair T. Pagnamenta, Barbara Parrini, Tara Paton, Andrew Pickles, David J. Posey, Fritz Poustka, Jiannis Ragoussis, Regina Regan, Wendy Roberts, Kathryn Roeder, Bernadette Roge, Michael L. Rutter, Sabine Schlitt, Naisha Shah, Val C. Sheffield, Latha Soorya, Inês Sousa, Vera Stoppioni, Nuala Sykes, Raffaella Tancredi, Ann P. Thompson, Susanne Thomson, Ana Tryfon, John Tsiantis, Herman Van Engeland, John B. Vincent, Fred Volkmar, JAS Vorstman, Simon Wallace, Kirsty Wing, Kerstin Wittemeyer, Shawn Wood, Danielle Zurawiecki, Lonnie Zwaigenbaum, Anthony J. Bailey, Agatino Battaglia, Rita M. Cantor, Hilary Coon, Michael L. Cuccaro, Geraldine Dawson, Sean Ennis, Christine M. Freitag, Daniel H. Geschwind, Jonathan L. Haines, Sabine M. Klauck, William M. McMahon, Elena Maestrini, Judith Miller, Anthony P. Monaco, Stanley F. Nelson, John I. Nurnberger, Jr., Guiomar Oliveira, Jeremy R. Parr, Margaret A. Pericak-Vance, Joseph Piven, Gerard D. Schellenberg, Stephen W. Scherer, Astrid M. Vicente, Thomas H. Wassink, Ellen M. Wijsman, Catalina Betancur, Joseph D. Buxbaum, Edwin H. Cook, Louise Gallagher, Michael Gill, Joachim Hallmayer, Andrew D. Paterson, James S. Sutcliffe, Peter Szatmari, Veronica J. Vieland, Hakon Hakonarson, Bernie Devlin

Hum Mol Genet. 2012 Nov 1; 21(21): 4781–4792. Published online 2012 Jul 26. doi: 10.1093/hmg/dds301

PMCID:: PMC3471395

Abstract Article PDF–203K

Select item 11902533.

PTEN Represses RNA Polymerase I Transcription by Disrupting the SL1 Complex

Cheng Zhang, Lucio Comai, Deborah L. Johnson

Mol Cell Biol. 2005 Aug; 25(16): 6899–6911. doi: 10.1128/MCB.25.16.6899-6911.2005

PMCID:: PMC1190253

Abstract Article PDF–565K

Select item 44491944.

Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis

Renate Voit, Jeanette Seiler, Ingrid Grummt

PLoS Genet. 2015 May; 11(5): e1005246. Published online 2015 May 29. doi: 10.1371/journal.pgen.1005246

PMCID:: PMC4449194

Abstract Article PDF–4.2M

Select item 18528485.

Identification of novel functional TBP-binding sites and general factor repertoires

Sergey Denissov, Marc van Driel, Renate Voit, Maarten Hekkelman, Tim Hulsen, Nouria Hernandez, Ingrid Grummt, Ron Wehrens, Hendrik Stunnenberg

EMBO J. 2007 Feb 21; 26(4): 944–954. Published online 2007 Feb 1. doi: 10.1038/sj.emboj.7601550

PMCID:: PMC1852848

Abstract Article PDF–488K

Select item 860706.

Repression of RNA Polymerase I Transcription by the Tumor Suppressor p53

Weiguo Zhai, Lucio Comai

Mol Cell Biol. 2000 Aug; 20(16): 5930–5938. doi: 10.1128/mcb.20.16.5930-5938.2000

PMCID:: PMC86070

Abstract Article PDF–744K

Select item 610927.

Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription

Renate Voit, Ingrid Grummt

Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24): 13631–13636. Published online 2001 Nov 6. doi: 10.1073/pnas.231071698

PMCID:: PMC61092

Abstract Article PDF–248K

Select item 29474018.

A genome-wide scan for common alleles affecting risk for autism

Richard Anney, Lambertus Klei, Dalila Pinto, Regina Regan, Judith Conroy, Tiago R. Magalhaes, Catarina Correia, Brett S. Abrahams, Nuala Sykes, Alistair T. Pagnamenta, Joana Almeida, Elena Bacchelli, Anthony J. Bailey, Gillian Baird, Agatino Battaglia, Tom Berney, Nadia Bolshakova, Sven Bölte, Patrick F. Bolton, Thomas Bourgeron, Sean Brennan, Jessica Brian, Andrew R. Carson, Guillermo Casallo, Jillian Casey, Su H. Chu, Lynne Cochrane, Christina Corsello, Emily L. Crawford, Andrew Crossett, Geraldine Dawson, Maretha de Jonge, Richard Delorme, Irene Drmic, Eftichia Duketis, Frederico Duque, Annette Estes, Penny Farrar, Bridget A. Fernandez, Susan E. Folstein, Eric Fombonne, Christine M. Freitag, John Gilbert, Christopher Gillberg, Joseph T. Glessner, Jeremy Goldberg, Jonathan Green, Stephen J. Guter, Hakon Hakonarson, Elizabeth A. Heron, Matthew Hill, Richard Holt, Jennifer L. Howe, Gillian Hughes, Vanessa Hus, Roberta Igliozzi, Cecilia Kim, Sabine M. Klauck, Alexander Kolevzon, Olena Korvatska, Vlad Kustanovich, Clara M. Lajonchere, Janine A. Lamb, Magdalena Laskawiec, Marion Leboyer, Ann Le Couteur, Bennett L. Leventhal, Anath C. Lionel, Xiao-Qing Liu, Catherine Lord, Linda Lotspeich, Sabata C. Lund, Elena Maestrini, William Mahoney, Carine Mantoulan, Christian R. Marshall, Helen McConachie, Christopher J. McDougle, Jane McGrath, William M. McMahon, Nadine M. Melhem, Alison Merikangas, Ohsuke Migita, Nancy J. Minshew, Ghazala K. Mirza, Jeff Munson, Stanley F. Nelson, Carolyn Noakes, Abdul Noor, Gudrun Nygren, Guiomar Oliveira, Katerina Papanikolaou, Jeremy R. Parr, Barbara Parrini, Tara Paton, Andrew Pickles, Joseph Piven, David J Posey, Annemarie Poustka, Fritz Poustka, Aparna Prasad, Jiannis Ragoussis, Katy Renshaw, Jessica Rickaby, Wendy Roberts, Kathryn Roeder, Bernadette Roge, Michael L. Rutter, Laura J. Bierut, John P. Rice, Jeff Salt, Katherine Sansom, Daisuke Sato, Ricardo Segurado, Lili Senman, Naisha Shah, Val C. Sheffield, Latha Soorya, Inês Sousa, Vera Stoppioni, Christina Strawbridge, Raffaella Tancredi, Katherine Tansey, Bhooma Thiruvahindrapduram, Ann P. Thompson, Susanne Thomson, Ana Tryfon, John Tsiantis, Herman Van Engeland, John B. Vincent, Fred Volkmar, Simon Wallace, Kai Wang, Zhouzhi Wang, Thomas H. Wassink, Kirsty Wing, Kerstin Wittemeyer, Shawn Wood, Brian L. Yaspan, Danielle Zurawiecki, Lonnie Zwaigenbaum, Catalina Betancur, Joseph D. Buxbaum, Rita M. Cantor, Edwin H. Cook, Hilary Coon, Michael L. Cuccaro, Louise Gallagher, Daniel H. Geschwind, Michael Gill, Jonathan L. Haines, Judith Miller, Anthony P. Monaco, John I. Nurnberger, Jr., Andrew D. Paterson, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Stephen W. Scherer, James S. Sutcliffe, Peter Szatmari, Astrid M. Vicente, Veronica J. Vieland, Ellen M. Wijsman, Bernie Devlin, Sean Ennis, Joachim Hallmayer

Hum Mol Genet. 2010 Oct 15; 19(20): 4072–4082. Published online 2010 Jul 27. doi: 10.1093/hmg/ddq307

PMCID:: PMC2947401

Abstract Article PDF–217K

Select item 18293719.

A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription

Julia J Gorski, Shalini Pathak, Kostya Panov, Taciana Kasciukovic, Tanya Panova, Jackie Russell, Joost C B M Zomerdijk

EMBO J. 2007 Mar 21; 26(6): 1560–1568. Published online 2007 Feb 22. doi: 10.1038/sj.emboj.7601601

PMCID:: PMC1829371

Abstract Article PDF–238K

Select item 14551910.

hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters

Gail Miller, Kostya I. Panov, J.Karsten Friedrich, Laura Trinkle-Mulcahy, Angus I. Lamond, Joost C.B.M. Zomerdijk

EMBO J. 2001 Mar 15; 20(6): 1373–1382. doi: 10.1093/emboj/20.6.1373

PMCID:: PMC145519

Abstract Article PDF–295K

Select item 1998511.

Cloning of murine RNA polymerase I-specific TAF factors: Conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1

Jutta Heix, Joost C. B. M. Zomerdijk, Ali Ravanpay, Robert Tjian, Ingrid Grummt

Proc Natl Acad Sci U S A. 1997 Mar 4; 94(5): 1733–1738. doi: 10.1073/pnas.94.5.1733

PMCID:: PMC19985

Abstract Article PDF–514K

Select item 14552412.

Acetylation of TAF_I68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription

Viola Muth, Sophie Nadaud, Ingrid Grummt, Renate Voit

EMBO J. 2001 Mar 15; 20(6): 1353–1362. doi: 10.1093/emboj/20.6.1353

PMCID:: PMC145524

Abstract Article PDF–271K

Select item 43425613.

Multiple Protein-Protein Interactions by RNA Polymerase I-Associated Factor PAF49 and Role of PAF49 in rRNA Transcription

Kazuo Yamamoto, Mika Yamamoto, Ken-ichi Hanada, Yasuhisa Nogi, Toshifumi Matsuyama, Masami Muramatsu

Mol Cell Biol. 2004 Jul; 24(14): 6338–6349. doi: 10.1128/MCB.24.14.6338-6349.2004

PMCID:: PMC434256

Abstract Article PDF–464K

Select item 130760314.

Multiple interactions between RNA polymerase I, TIF-IA and TAF_I subunits regulate preinitiation complex assembly at the ribosomal gene promoter

Xuejun Yuan, Jian Zhao, Hanswalter Zentgraf, Urs Hoffmann-Rohrer, Ingrid Grummt

EMBO Rep. 2002 Nov; 3(11): 1082–1087. doi: 10.1093/embo-reports/kvf212

PMCID:: PMC1307603

Abstract Article PDF–284K

Select item 117062615.

Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.

P Jansa, S W Mason, U Hoffmann-Rohrer, I Grummt

EMBO J. 1998 May 15; 17(10): 2855–2864. doi: 10.1093/emboj/17.10.2855

PMCID:: PMC1170626

Summary PDF–483K

Select item 649756916.

Spindle assembly checkpoint inhibition can resensitize p53-null stem cells to cancer chemotherapy

Changlong Liu, Carolyn E. Banister, Phillip J. Buckhaults

Cancer Res. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Cancer Res. 2019 May 1; 79(9): 2392–2403. Published online 2019 Mar 12. doi: 10.1158/0008-5472.CAN-18-3024

PMCID:: PMC6497569

Abstract Article PDF–2.2M

Select item 334973417.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695

PMCID:: PMC3349734

Abstract Article PDF–377K

Select item 773761018.

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy

Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker

EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948

PMCID:: PMC7737610

Abstract Article PDF–3.7M

Select item 956995519.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 929024120.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Abstract Article PDF–8.2M

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