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Select item 53846371.

Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells

Subhankar Dolai, Li Xie, Dan Zhu, Tao Liang, Tairan Qin, Huanli Xie, Youhou Kang, Edwin R. Chapman, Herbert Y. Gaisano

Diabetes. 2016 Jul; 65(7): 1962–1976. Published online 2016 Apr 26. doi: 10.2337/db15-1436

PMCID:: PMC5384637

Article PDF–2.5M

Select item 42786792.

Lateral Diffusion of Proteins on Supported Lipid Bilayers: Additive Friction of Synaptotagmin 7 C2A–C2B Tandem Domains

Joseph K. Vasquez, Kan Chantranuvatana, Daniel T. Giardina, Matthew D. Coffman, Jefferson D. Knight

Biochemistry. 2014 Dec 23; 53(50): 7904–7913. Published online 2014 Dec 1. doi: 10.1021/bi5012223

PMCID:: PMC4278679

Article PDF–4.8M

Select item 21934253.

The Exocytosis-Regulatory Protein Synaptotagmin VII Mediates Cell Invasion by Trypanosoma cruzi

Elisabet V. Caler, Sabyasachi Chakrabarti, Kimberly T. Fowler, Swathi Rao, Norma W. Andrews

J Exp Med. 2001 May 7; 193(9): 1097–1104. doi: 10.1084/jem.193.9.1097

PMCID:: PMC2193425

Article PDF–378K

Select item 77337864.

Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity

Qiu-Wen Wang, Si-Yao Lu, Yao-Nan Liu, Yun Chen, Hui Wei, Wei Shen, Yan-Fen Chen, Chong-Lei Fu, Ying-Han Wang, Anbang Dai, Xuan Huang, Fred H. Gage, Qi Xu, Jun Yao

Proc Natl Acad Sci U S A. 2020 Dec 8; 117(49): 31438–31447. Published online 2020 Nov 23. doi: 10.1073/pnas.2016416117

Correction in:: Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2111933118.

PMCID:: PMC7733786

Article PDF–2.5M

Select item 70491555.

Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice

Wei Shen, Qiu-Wen Wang, Yao-Nan Liu, Maria C. Marchetto, Sara Linker, Si-Yao Lu, Yun Chen, Chuihong Liu, Chongye Guo, Zhikai Xing, Wei Shi, John R. Kelsoe, Martin Alda, Hongwei Wang, Yi Zhong, Sen-Fang Sui, Mei Zhao, Yiming Yang, Shuangli Mi, Liping Cao, Fred H. Gage, Jun Yao

Proc Natl Acad Sci U S A. 2020 Feb 25; 117(8): 4392–4399. Published online 2020 Feb 10. doi: 10.1073/pnas.1918165117

PMCID:: PMC7049155

Article PDF–1.2M

Select item 64288686.

Membrane-Binding Cooperativity and Coinsertion by C2AB Tandem Domains of Synaptotagmins 1 and 7

Hai T. Tran, Lauren H. Anderson, Jefferson D. Knight

Biophys J. 2019 Mar 19; 116(6): 1025–1036. Published online 2019 Feb 5. doi: 10.1016/j.bpj.2019.01.035

PMCID:: PMC6428868

Article PDF–1.5M

Select item 63672067.

Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells

Zhenhua Fei, Wei Gao, Raoying Xie, Ganzhu Feng, Xiaolin Chen, Yiyan Jiang

Biosci Rep. 2019 Feb 28; 39(2): BSR20181298. Prepublished online 2019 Jan 15. Published online 2019 Feb 8. doi: 10.1042/BSR20181298

PMCID:: PMC6367206

Article PDF–1.1M

Select item 58924118.

Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses

Josef Turecek, Skyler L. Jackman, Wade G. Regehr

Nature. Author manuscript; available in PMC 2018 Apr 30.

Published in final edited form as: Nature. 2017 Nov 23; 551(7681): 503–506. Published online 2017 Oct 30. doi: 10.1038/nature24474

PMCID:: PMC5892411

Article PDF–2.8M

Select item 55576609.

Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed at Atomic Detail

Josh V. Vermaas, Emad Tajkhorshid

Biochemistry. Author manuscript; available in PMC 2017 Aug 15.

Published in final edited form as: Biochemistry. 2017 Jan 10; 56(1): 281–293. Published online 2016 Dec 20. doi: 10.1021/acs.biochem.6b00468

PMCID:: PMC5557660

Article PDF–3.7M

Select item 349448210.

Hydrophobic Contributions to the Membrane Docking of Synaptotagmin 7 C2A Domain: Mechanistic Contrast Between Isoforms 1 and 7

Devin S. Brandt, Matthew D. Coffman, Joseph J. Falke, Jefferson D. Knight

Biochemistry. Author manuscript; available in PMC 2013 Oct 2.

Published in final edited form as: Biochemistry. 2012 Oct 2; 51(39): 7654–7664. Published online 2012 Sep 21. doi: 10.1021/bi3007115

Correction in:: Biochemistry. 2013 Mar 5; 52(9): 1649.

PMCID:: PMC3494482

Article PDF–1.0M

Select item 122266711.

Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human.

Mitsunori Fukuda, Yukie Ogata, Chika Saegusa, Eiko Kanno, Katsuhiko Mikoshiba

Biochem J. 2002 Jul 1; 365(Pt 1): 173–180. doi: 10.1042/BJ20011877

PMCID:: PMC1222667

Summary PDF–351K

Select item 31099112.

Prediction of Gene Function by Genome-Scale Expression Analysis: Prostate Cancer-Associated Genes

Michael G. Walker, Wayne Volkmuth, Einat Sprinzak, David Hodgson, Tod Klingler

Genome Res. 1999 Dec; 9(12): 1198–1203. doi: 10.1101/gr.9.12.1198

PMCID:: PMC310991

Article PDF–201K

Select item 510212113.

Plexin C1 deficiency permits synaptotagmin 7–mediated macrophage migration and enhances mammalian lung fibrosis

Xueyan Peng, Meagan Moore, Aditi Mathur, Yang Zhou, Huanxing Sun, Ye Gan, Jose D. Herazo-Maya, Naftali Kaminski, Xinyuan Hu, Hongyi Pan, Changwan Ryu, Awo Osafo-Addo, Robert J. Homer, Carol Feghali-Bostwick, Wassim H. Fares, Mridu Gulati, Buqu Hu, Chun-Geun Lee, Jack A. Elias, Erica L. Herzog

FASEB J. 2016 Dec; 30(12): 4056–4070. Published online 2016 Sep 8. doi: 10.1096/fj.201600373R

PMCID:: PMC5102121

Article

Select item 412386214.

Genome-Wide Association Study of Plasma N6 Polyunsaturated Fatty Acids within the CHARGE Consortium

Weihua Guan, Brian T. Steffen, Rozenn N. Lemaitre, Jason H.Y. Wu, Toshiko Tanaka, Ani Manichaikul, Millennia Foy, Stephen S. Rich, Lu Wang, Jennifer A. Nettleton, Weihong Tang, Xiangjun Gu, Stafania Bandinelli, Irena B. King, Barbara McKnight, Bruce M. Psaty, David Siscovick, Luc Djousse, Yii-Der Ida Chen, Luigi Ferrucci, Myriam Fornage, Dariush Mozafarrian, Michael Y. Tsai, Lyn M. Steffen

Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Circ Cardiovasc Genet. 2014 Jun; 7(3): 321–331. Published online 2014 May 13. doi: 10.1161/CIRCGENETICS.113.000208

PMCID:: PMC4123862

Article PDF–430K

Select item 901632015.

A Hypoxia-Induced SCF^FBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis

Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou

Cancer Res Treat. 2022 Apr; 54(2): 525–540. Published online 2021 Jun 29. doi: 10.4143/crt.2021.373

PMCID:: PMC9016320

Article PDF–3.0M

Select item 737208116.

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245

PMCID:: PMC7372081

Article PDF–2.0M

Select item 638658817.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Article PDF–1.7M

Select item 497239718.

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

Zhenhuan Guo, Lisa J Neilson, Hang Zhong, Paul S Murray, Megha Vaman Rao, Sara Zanivan, Ronen Zaidel-Bar

Sci Signal. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Sci Signal. 2014 Dec 2; 7(354): rs7. Published online 2014 Dec 2. doi: 10.1126/scisignal.2005473

PMCID:: PMC4972397

Article PDF–3.1M

Select item 694204419.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Article PDF–10M

Select item 545599620.

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

Cell Syst. Author manuscript; available in PMC 2017 Sep 28.

Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001

PMCID:: PMC5455996

Article PDF–3.1M

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