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Items: 1 to 20 of 129

1.
ASH2L drives proliferation and sensitivity to bleomycin and other genotoxins in Hodgkin’s lymphoma and testicular cancer cells
Daniel Constantin, Christian Widmann
Cell Death Dis. 2020 Nov; 11(11): 1019. Published online 2020 Nov 30. doi: 10.1038/s41419-020-03231-0
Correction in:
Cell Death Dis. 2021 Jan; 12(1): 96.
PMCID:
PMC7705021
AbstractArticlePDF–1.7M
2.
Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia
Jill S. Butler, Yi Hua Qiu, Nianxiang Zhang, Suk-Young Yoo, Kevin R. Coombes, Sharon Y.R. Dent, Steven M. Kornblau
Leuk Lymphoma. Author manuscript; available in PMC 2018 Jun 11.
Published in final edited form as: Leuk Lymphoma. 2017 May; 58(5): 1207–1218. Published online 2016 Oct 13. doi: 10.1080/10428194.2016.1235272
PMCID:
PMC5994918
AbstractArticlePDF–3.7M
3.
Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding
Yong Chen, Bingbing Wan, Kevin C Wang, Fang Cao, Yuting Yang, Angeline Protacio, Yali Dou, Howard Y Chang, Ming Lei
EMBO Rep. 2011 Aug; 12(8): 797–803. Published online 2011 Jun 10. doi: 10.1038/embor.2011.101
PMCID:
PMC3147254
AbstractArticlePDF–1.4M
4.
ASH2L is involved in promotion of endometrial cancer progression via upregulation of PAX2 transcription
Kai Zeng, Yi Wu, Chunyu Wang, Shengli Wang, Hongmiao Sun, Renlong Zou, Ge Sun, Huijuan Song, Wei Liu, Ning Sun, Shan Wei, Wensu Liu, Yingjie Su, Tingting Zhou, Yi Zhang, Yue Zhao
Cancer Sci. 2020 Jun; 111(6): 2062–2077. Published online 2020 May 23. doi: 10.1111/cas.14413
PMCID:
PMC7293091
AbstractArticlePDF–2.9M
5.
Crystal structure of the trithorax group protein Ash2L reveals a Forkhead-like DNA binding domain
Sabina Sarvan, Vanja Avdic, Véronique Tremblay, Chandra-Prakash Chaturvedi, Pamela Zhang, Sylvain Lanouette, Alexandre Blais, Joseph S. Brunzelle, Marjorie Brand, Jean-François Couture
Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Apr 10.
Published in final edited form as: Nat Struct Mol Biol. 2011 Jun 5; 18(7): 857–859. Published online 2011 Jun 5. doi: 10.1038/nsmb.2093
PMCID:
PMC3983046
AbstractArticlePDF–880K
6.
ASH2L Regulates Ubiquitylation Signaling to MLL: Trans-regulation of H3 K4 Methylation in Higher Eukaryotes
Lipeng Wu, Shirley Y. Lee, Bo Zhou, Uyen T Nguyen, Tom Muir, Song Tan, Yali Dou
Mol Cell. Author manuscript; available in PMC 2014 Mar 28.
Published in final edited form as: Mol Cell. 2013 Mar 28; 49(6): 1108–1120. Published online 2013 Feb 28. doi: 10.1016/j.molcel.2013.01.033
PMCID:
PMC3615107
AbstractArticlePDF–2.7M
7.
The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation
Dieter Pullirsch, Renate Härtel, Hiroyuki Kishimoto, Martin Leeb, Günter Steiner, Anton Wutz
Development. 2010 Mar 15; 137(6): 935–943. doi: 10.1242/dev.035956
PMCID:
PMC2834461
AbstractArticle
8.
Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma
Yan Chen, Zhonghu Li, Mengyun Zhang, Bo Wang, Jiaxin Ye, Yang Zhang, Di Tang, Dandan Ma, Weidong Jin, Xiaowu Li, Shuguang Wang
J Exp Clin Cancer Res. 2019; 38: 466. Published online 2019 Nov 12. doi: 10.1186/s13046-019-1436-0
Correction in:
J Exp Clin Cancer Res. 2021; 40: 137.
PMCID:
PMC6852927
AbstractArticlePDF–7.0M
9.
EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas
Parsa Erfani, Jessica Tome-Garcia, Peter Canoll, Fiona Doetsch, Nadejda M Tsankova
Epigenetics. 2015 Jun; 10(6): 496–507. Published online 2015 May 21. doi: 10.1080/15592294.2015.1042645
PMCID:
PMC4622924
AbstractArticlePDF–788K
10.
Ash2L enables P53–dependent apoptosis by favoring stable transcription pre–initiation complex formation on its pro-apoptotic target promoters
Sathish Kumar Mungamuri, Shaomeng Wang, James J. Manfredi, Wei Gu, Stuart A. Aaronson
Oncogene. Author manuscript; available in PMC 2015 Nov 7.
Published in final edited form as: Oncogene. 2015 May 7; 34(19): 2461–2470. Published online 2014 Jul 14. doi: 10.1038/onc.2014.198
PMCID:
PMC4295002
AbstractArticlePDF–1.1M
11.
Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30
Yong Chen, Fang Cao, Bingbing Wan, Yali Dou, Ming Lei
Cell Res. 2012 Mar; 22(3): 598–602. Published online 2012 Jan 10. doi: 10.1038/cr.2012.9
PMCID:
PMC3292303
ArticlePDF–510K
12.
Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin
Young-Tae Lee, Alex Ayoub, Sang-Ho Park, Liang Sha, Jing Xu, Fengbiao Mao, Wei Zheng, Yang Zhang, Uhn-Soo Cho, Yali Dou
Nat Commun. 2021; 12: 2953. Published online 2021 May 19. doi: 10.1038/s41467-021-23268-9
PMCID:
PMC8134635
AbstractArticlePDF–3.4M
13.
CircASH2L facilitates tumor-like biologic behaviours and inflammation of fibroblast-like synoviocytes via miR-129-5p/HIPK2 axis in rheumatoid arthritis
Xia Li, Meiting Qu, Jie Zhang, Kuanyin Chen, Xianghui Ma
J Orthop Surg Res. 2021; 16: 302. Published online 2021 May 8. doi: 10.1186/s13018-021-02432-3
PMCID:
PMC8106127
AbstractArticlePDF–5.1M
14.
Molecular Basis for DPY-30 Association to COMPASS-like and NURF Complexes
Véronique Tremblay, Pamela Zhang, Chandra-Prakash Chaturvedi, Janet Thornton, Joseph S. Brunzelle, Georgios Skiniotis, Ali Shilatifard, Marjorie Brand, Jean-François Couture
Structure. Author manuscript; available in PMC 2018 Mar 1.
Published in final edited form as: Structure. 2014 Dec 2; 22(12): 1821–1830. Published online 2014 Nov 20. doi: 10.1016/j.str.2014.10.002
PMCID:
PMC5832440
AbstractArticlePDF–1.2M
15.
NF-Y Recruits Ash2L to Impart H3K4 Trimethylation on CCAAT Promoters
Andrea Fossati, Diletta Dolfini, Giacomo Donati, Roberto Mantovani
PLoS One. 2011; 6(3): e17220. Published online 2011 Mar 21. doi: 10.1371/journal.pone.0017220
PMCID:
PMC3061855
AbstractArticlePDF–1.4M
16.
A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit
Gerd A. Blobel, Stephan Kadauke, Eric Wang, Alan W. Lau, Johannes Zuber, Margaret M. Chou, Christopher R. Vakoc
Mol Cell. Author manuscript; available in PMC 2010 Dec 25.
Published in final edited form as: Mol Cell. 2009 Dec 25; 36(6): 970. doi: 10.1016/j.molcel.2009.12.001
PMCID:
PMC2818742
AbstractArticlePDF–3.4M
17.
Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex
Iain W. McKinnell, Jeff Ishibashi, Fabien Le Grand, Vincent J. G. Punch, Gregory C. Addicks, Jack F. Greenblatt, F. Jeffrey Dilworth, Michael A. Rudnicki
Nat Cell Biol. Author manuscript; available in PMC 2009 Sep 8.
Published in final edited form as: Nat Cell Biol. 2008 Jan; 10(1): 77–84. Published online 2007 Dec 9. doi: 10.1038/ncb1671
PMCID:
PMC2739814
AbstractArticlePDF–1.9M
18.
The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex
Jianming Han, Tingting Li, Yanjing Li, Muchun Li, Xiaoman Wang, Chao Peng, Chen Su, Na Li, Yiwen Li, Ying Xu, Yong Chen
Nucleic Acids Res. 2019 Nov 4; 47(19): 10426–10438. Published online 2019 Sep 23. doi: 10.1093/nar/gkz819
PMCID:
PMC6821195
AbstractArticlePDF–3.9M
19.
Dissecting KMT2D missense mutations in Kabuki syndrome patients
Dario Cocciadiferro, Bartolomeo Augello, Pasquelena De Nittis, Jiyuan Zhang, Barbara Mandriani, Natascia Malerba, Gabriella M Squeo, Alessandro Romano, Barbara Piccinni, Tiziano Verri, Lucia Micale, Laura Pasqualucci, Giuseppe Merla
Hum Mol Genet. 2018 Nov 1; 27(21): 3651–3668. Published online 2018 Jun 22. doi: 10.1093/hmg/ddy241
PMCID:
PMC6488975
AbstractArticlePDF–818K
20.
Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex
Sara Weirich, Srikanth Kudithipudi, Albert Jeltsch
Mol Oncol. 2017 Apr; 11(4): 373–387. Published online 2017 Mar 10. doi: 10.1002/1878-0261.12041
PMCID:
PMC5527479
AbstractArticlePDF–1.1M

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