PMC Links for Gene (Select 9154) - PMC

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Items: 13

Select item 44335431.

Defective hCNT1 Transport Contributes to Gemcitabine Chemoresistance in Ovarian Cancer Subtypes: Overcoming Transport Defects Using a Nanoparticle Approach

Sau Wai Hung, Sean Marrache, Shannon Cummins, Yangzom D. Bhutia, Hardik Mody, Shelley B. Hooks, Shanta Dhar, Rajgopal Govindarajan

Cancer Lett. Author manuscript; available in PMC 2016 Apr 10.

Published in final edited form as: Cancer Lett. 2015 Apr 10; 359(2): 233–240. Published online 2015 Jan 16. doi: 10.1016/j.canlet.2015.01.017

PMCID:: PMC4433543

Abstract Article PDF–1.2M

Select item 36743792.

Concentrative nucleoside transporter 1 (hCNT1) promotes phenotypic changes relevant to tumor biology in a translocation-independent manner

S Pérez-Torras, A Vidal-Pla, P Cano-Soldado, I Huber-Ruano, A Mazo, M Pastor-Anglada

Cell Death Dis. 2013 May; 4(5): e648. Published online 2013 May 30. doi: 10.1038/cddis.2013.173

PMCID:: PMC3674379

Abstract Article PDF–1.6M

Select item 30481663.

CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells

Yangzom D. Bhutia, Sau Wai Hung, Bhavi Patel, Dylan Lovin, Rajgopal Govindarajan

Cancer Res. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Cancer Res. 2011 Mar 1; 71(5): 1825–1835. Published online 2011 Feb 22. doi: 10.1158/0008-5472.CAN-10-2736

PMCID:: PMC3048166

Abstract Article PDF–2.8M

Select item 39361214.

The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family

Nicolas Skrypek, Bélinda Duchêne, Mohamed Hebbar, Emmanuelle Leteurtre, Isabelle Van Seuningen, Nicolas Jonckheere

Oncogene. Author manuscript; available in PMC 2014 Mar 11.

Published in final edited form as: Oncogene. 2013 Mar; 32(13): 1714–1723. Published online 2012 May 14. doi: 10.1038/onc.2012.179

PMCID:: PMC3936121

Abstract Article

Select item 54654795.

Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance

Ras Mulinta, Sylvia Y. M. Yao, Amy M. L. Ng, Carol E. Cass, James D. Young

J Biol Chem. 2017 Jun 9; 292(23): 9505–9522. Published online 2017 Apr 6. doi: 10.1074/jbc.M116.743997

PMCID:: PMC5465479

Abstract Article PDF–4.5M

Select item 44844246.

The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2

Nicolas Skrypek, Romain Vasseur, Audrey Vincent, Bélinda Duchêne, Isabelle Van Seuningen, Nicolas Jonckheere

Oncotarget. 2015 May 10; 6(13): 10853–10867. Published online 2015 Mar 26. doi: 10.18632/oncotarget.3414

PMCID:: PMC4484424

Abstract Article PDF–4.0M

Select item 25367887.

Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes

Rajgopal Govindarajan, Christopher J. Endres, Dale Whittington, Edward LeCluyse, Marçal Pastor-Anglada, Chung-Ming Tse, Jashvant D. Unadkat

Am J Physiol Gastrointest Liver Physiol. 2008 Sep; 295(3): G570–G580. Published online 2008 Jul 17. doi: 10.1152/ajpgi.00542.2007

PMCID:: PMC2536788

Abstract Article

Select item 29668598.

Gemcitabine Metabolic and Transporter Gene Polymorphisms Are Associated with Drug Toxicity and Efficacy in Patients with Locally Advanced Pancreatic Cancer

Motofumi Tanaka, Milind Javle, Xiaoqun Dong, Cathy Eng, James L. Abbruzzese, Donghui Li

Cancer. Author manuscript; available in PMC 2011 Nov 15.

Published in final edited form as: Cancer. 2010 Nov 15; 116(22): 5325–5335. doi: 10.1002/cncr.25282

PMCID:: PMC2966859

Abstract Article PDF–390K

Select item 54306169.

Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions

Josyf C. Mychaleckyj, Alexandre Havt, Uma Nayak, Relana Pinkerton, Emily Farber, Patrick Concannon, Aldo A. Lima, Richard L. Guerrant

Mol Biol Evol. 2017 Mar; 34(3): 559–574. Published online 2017 Jan 18. doi: 10.1093/molbev/msw249

PMCID:: PMC5430616

Abstract Article PDF–1.6M

Select item 280265510.

Single Nucleotide Polymorphisms of Gemcitabine Metabolic Genes and Pancreatic Cancer Survival and Drug Toxicity

Taro Okazaki, Milind Javle, Motofumi Tanaka, James L. Abbruzzese, Donghui Li

Clin Cancer Res. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Clin Cancer Res. 2010 Jan 1; 16(1): 320–329. Published online 2009 Dec 22. doi: 10.1158/1078-0432.CCR-09-1555

PMCID:: PMC2802655

Abstract Article PDF–700K

Select item 326295211.

Genome-wide association analysis of age-at-onset in Alzheimer’s disease

M. Ilyas Kamboh, M. Michael Barmada, F. Yesim Demirci, Ryan L. Minster, Minerva M. Carrasquillo, V. Shane Pankratz, Steven G. Younkin, Andrew J. Saykin, The Alzheimer’s Disease Neuroimaging Initiative, Robert A. Sweet, Eleanor Feingold, Steven T. DeKosky, Oscar L. Lopez

Mol Psychiatry. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Mol Psychiatry. 2012 Dec; 17(12): 1340–1346. Published online 2011 Oct 18. doi: 10.1038/mp.2011.135