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Select item 99415101.

TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis

Yuzhen Wang, Yingchun Wang, Wen Liu, Lu Ding, Xiaodi Zhang, Bo Wang, Zheng Tong, Xuetian Yue, Chunyang Li, Liyun Xu, Zhuanchang Wu, Xiaohong Liang, Chunhong Ma, Lifen Gao

Cell Death Dis. 2023 Feb; 14(2): 141. Published online 2023 Feb 20. doi: 10.1038/s41419-023-05678-3

PMCID:: PMC9941510

Abstract Article PDF–6.1M

Select item 66431072.

TIMD4 rs6882076 SNP Is Associated with Decreased Levels of Triglycerides and the Risk of Coronary Heart Disease and Ischemic Stroke

Eksavang Khounphinith, Rui-Xing Yin, Xiao-Li Cao, Feng Huang, Jin-Zhen Wu, Hui Li

Int J Med Sci. 2019; 16(6): 864–871. Published online 2019 Jun 2. doi: 10.7150/ijms.31729

PMCID:: PMC6643107

Abstract Article PDF–375K

Select item 55056213.

Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells

Brian Sims, Anitra L Farrow, Sparkle D Williams, Anju Bansal, Alexandre Krendelchtchikov, Linlin Gu, Qiana L Matthews

Int J Nanomedicine. 2017; 12: 4823–4833. Published online 2017 Jul 6. doi: 10.2147/IJN.S132762

PMCID:: PMC5505621

Abstract Article PDF–747K

Select item 48158844.

TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner

Qianqian Zhang, Hongxing Wang, Xiaodong Wu, Bing Liu, Wen Liu, Rong Wang, Xiaohong Liang, Chunhong Ma, Lifen Gao

Br J Cancer. 2015 Nov 17; 113(10): 1484–1492. Published online 2015 Oct 29. doi: 10.1038/bjc.2015.323

PMCID:: PMC4815884

Abstract Article PDF–2.3M

Select item 47101955.

Expression of Tim4 in Glioma and its Regulatory Role in LN-18 Glioma Cells

Weiguo Li, Xingang Li, Shujun Xu, Xiangyu Ma, Qiujie Zhang

Med Sci Monit. 2016; 22: 77–82. Published online 2016 Jan 7. doi: 10.12659/MSM.894963

PMCID:: PMC4710195

Abstract Article PDF–827K

Select item 40018906.

Increased expression of human T-cell immunoglobulin- and mucin-domain-containing molecule-4 in peripheral blood mononuclear cells from patients with system lupus erythematosus

Peiqing Zhao, Liyun Xu, Piming Wang, Xiaohong Liang, Jianni Qi, Peng Liu, Chun Guo, Lining Zhang, Chunhong Ma, Lifen Gao

Cell Mol Immunol. 2010 Mar; 7(2): 152–156. Published online 2010 Feb 8. doi: 10.1038/cmi.2009.118

PMCID:: PMC4001890

Abstract Article PDF–208K

Select item 38005927.

Cockroach Allergen Bla g 7 Promotes TIM4 Expression in Dendritic Cells Leading to Th2 Polarization

Lingxiao Xu, Miaojia Zhang, Wenjing Ma, Shanshan Jin, Weijuan Song, Shaoheng He

Mediators Inflamm. 2013; 2013: 983149. Published online 2013 Sep 24. doi: 10.1155/2013/983149

PMCID:: PMC3800592

Abstract Article PDF–2.0M

Select item 31961348.

Glioma-derived T Cell Immunoglobulin- and Mucin Domain-containing Molecule-4 (TIM4) Contributes to Tumor Tolerance

Lunshan Xu, Hualiang Xiao, Minhui Xu, Chun Zhou, Liang Yi, Hong Liang

J Biol Chem. 2011 Oct 21; 286(42): 36694–36699. Published online 2011 Sep 6. doi: 10.1074/jbc.M111.292540

PMCID:: PMC3196134

Abstract Article PDF–1.2M

Select item 82245649.

EphA2 Interacts with Tim-4 through Association between Its FN3 Domain and the IgV Domain of Tim-4

Byeongjin Moon, Susumin Yang, Kwangwoo Kim, Juyeon Lee, Dongtak Jeong, Daeho Park

Cells. 2021 Jun; 10(6): 1290. Published online 2021 May 22. doi: 10.3390/cells10061290

PMCID:: PMC8224564

Abstract Article PDF–1.9M

Select item 793122510.

Platelet‐derived extracellular vesicles are increased in sera of Alzheimer's disease patients, as revealed by Tim4‐based assays

Haruki Odaka, Keiko Hiemori, Asako Shimoda, Kazunari Akiyoshi, Hiroaki Tateno

FEBS Open Bio. 2021 Mar; 11(3): 741–752. Published online 2021 Feb 3. doi: 10.1002/2211-5463.13068

PMCID:: PMC7931225

Abstract Article PDF–789K

Select item 577382211.

Association between the TIMD4-HAVCR1 variants and serum lipid levels, coronary heart disease and ischemic stroke risk and atorvastatin lipid-lowering efficacy

Qing-Hui Zhang, Rui-Xing Yin, Wu-Xian Chen, Xiao-Li Cao, Yu-Ming Chen

Biosci Rep. 2018 Feb 28; 38(1): BSR20171058. Prepublished online 2018 Jan 19. Published online 2018 Jan 19. doi: 10.1042/BSR20171058

PMCID:: PMC5773822

Abstract Article PDF–1.7M

Select item 490723012.

Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry

Bethany A. Rhein, Rachel B. Brouillette, Grace A. Schaack, John A. Chiorini, Wendy Maury

J Virol. 2016 Jul 1; 90(13): 6097–6111. Prepublished online 2016 Apr 27. Published online 2016 Jun 10. doi: 10.1128/JVI.00100-16

PMCID:: PMC4907230

Abstract Article PDF–2.9M

Select item 315343713.

TIM-4, a Receptor for Phosphatidylserine, Controls Adaptive Immunity by Regulating the Removal of Antigen-Specific T Cells

Lee A. Albacker, Piia Karisola, Ya-Jen Chang, Sarah E. Umetsu, Meixia Zhou, Omid Akbari, Norimoto Kobayashi, Nicole Baumgarth, Gordon J. Freeman, Dale T. Umetsu, Rosemarie H. DeKruyff

J Immunol. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: J Immunol. 2010 Dec 1; 185(11): 6839–6849. Published online 2010 Oct 29. doi: 10.4049/jimmunol.1001360

PMCID:: PMC3153437

Abstract Article PDF–1.4M

Select item 311574014.

The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms

David M. Dorfman, Jason L. Hornick, Aliakbar Shahsafaei, Gordon J. Freeman

Hum Pathol. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Hum Pathol. 2010 Oct; 41(10): 1486–1494. Published online 2010 Jul 24. doi: 10.1016/j.humpath.2010.04.005

PMCID:: PMC3115740

Abstract Article PDF–4.6M

Select item 710696215.

IL‐6 promotes metastasis of non‐small‐cell lung cancer by up‐regulating TIM‐4 via NF‐κB

Wen Liu, Hongxing Wang, Fuxiang Bai, Lu Ding, Yanyan Huang, Changchang Lu, Siyuan Chen, Chunyang Li, Xuetian Yue, Xiaohong Liang, Chunhong Ma, Liyun Xu, Lifen Gao

Cell Prolif. 2020 Mar; 53(3): e12776. Published online 2020 Feb 5. doi: 10.1111/cpr.12776

PMCID:: PMC7106962

Abstract Article PDF–2.7M

Select item 431514616.

Genetic and environmental determinants of the susceptibility of Amerindian derived populations for having hypertriglyceridemia

Carlos A. Aguilar-Salinas, Teresa Tusie-Luna, Päivi Pajukanta

Metabolism. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Metabolism. 2014 Jul; 63(7): 887–894. Published online 2014 Mar 30. doi: 10.1016/j.metabol.2014.03.012

PMCID:: PMC4315146

Abstract Article PDF–434K

Select item 361069617.

TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine

Stephanie Jemielity, Jinyize J. Wang, Ying Kai Chan, Asim A. Ahmed, Wenhui Li, Sheena Monahan, Xia Bu, Michael Farzan, Gordon J. Freeman, Dale T. Umetsu, Rosemarie H. DeKruyff, Hyeryun Choe

PLoS Pathog. 2013 Mar; 9(3): e1003232. Published online 2013 Mar 28. doi: 10.1371/journal.ppat.1003232

PMCID:: PMC3610696

Abstract Article PDF–1.2M

Select item 938901418.

TIM-4 in macrophages contributes to nasal polyp formation through the TGF-β1–mediated epithelial to mesenchymal transition in nasal epithelial cells

Danxue Qin, Peiqiang Liu, Huiqin Zhou, Jing Jin, Wanyang Gong, Kunyu Liu, Siyuan Chen, Jingyu Huang, Wenjun Fan, Zezhang Tao, Yu Xu

Front Immunol. 2022; 13: 941608. Published online 2022 Aug 5. doi: 10.3389/fimmu.2022.941608

PMCID:: PMC9389014

Abstract Article PDF–10M

Select item 911560419.

Tim-4⁺ Cavity-Resident Macrophages Impair Anti-Tumor CD8⁺ T cell Immunity

Andrew Chow, Sara Schad, Michael D. Green, Matthew D. Hellmann, Viola Allaj, Nicholas Ceglia, Giulia Zago, Nisargbhai S. Shah, Sai Kiran Sharma, Marissa Mattar, Joseph Chan, Hira Rizvi, Hong Zhong, Cailian Liu, Yonina Bykov, Dmitriy Zamarin, Hongyu Shi, Sadna Budhu, Corrin Wohlhieter, Fathema Uddin, Aditi Gupta, Inna Khodos, Jessica J. Waninger, Angel Qin, Geoffrey J. Markowitz, Vivek Mittal, Vinod Balachandran, Jennifer N. Durham, Dung T. Le, Weiping Zou, Sohrab P. Shah, Andrew McPherson, Katherine Panageas, Jason S. Lewis, Justin S.A. Perry, Elisa de Stanchina, Triparna Sen, John Thomas Poirier, Jedd D. Wolchok, Charles M. Rudin, Taha Merghoub

Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 973–988.e9. Published online 2021 Jun 10. doi: 10.1016/j.ccell.2021.05.006

PMCID:: PMC9115604

Abstract Article PDF–3.8M

Select item 740861020.

Mertk Interacts with Tim-4 to Enhance Tim-4-Mediated Efferocytosis

Byeongjin Moon, Juyeon Lee, Sang-Ah Lee, Chanhyuk Min, Hyunji Moon, Deokhwan Kim, Susumin Yang, Heera Moon, Jaeseon Jeon, Young-Eun Joo, Daeho Park

Cells. 2020 Jul; 9(7): 1625. Published online 2020 Jul 6. doi: 10.3390/cells9071625

PMCID:: PMC7408610

Abstract Article PDF–8.2M

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