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Select item 49494451.

F-actin dampens NLRP3 inflammasome activity via Flightless-I and LRRFIP2

Danielle Burger, Céline Fickentscher, Philippe de Moerloose, Karim J. Brandt

Sci Rep. 2016; 6: 29834. Published online 2016 Jul 19. doi: 10.1038/srep29834

PMCID:: PMC4949445

Abstract Article PDF–1.9M

Select item 5485592.

Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis

Jun Liu, Anne G. Bang, Chris Kintner, Anthony P. Orth, Sumit K. Chanda, Sheng Ding, Peter G. Schultz

Proc Natl Acad Sci U S A. 2005 Feb 8; 102(6): 1927–1932. Published online 2005 Jan 26. doi: 10.1073/pnas.0409472102

PMCID:: PMC548559

Abstract Article PDF–454K

Select item 30641453.

Unambiguous Characterization of Site-specific Phosphorylation of Leucine-rich Repeat Fli-I-interacting Protein 2 (LRRFIP2) in Toll-like Receptor 4 (TLR4)-mediated Signaling

Harsha P. Gunawardena, Yi Huang, Roma Kenjale, Haiyang Wang, Ling Xie, Xian Chen

J Biol Chem. 2011 Apr 1; 286(13): 10897–10910. Published online 2011 Jan 10. doi: 10.1074/jbc.M110.168179

PMCID:: PMC3064145

Abstract Article PDF–2.3M

Select item 52458674.

Il-Taeg Cho, Youngshin Lim, Jeffrey A. Golden, Ginam Cho

PLoS One. 2017; 12(1): e0170282. Published online 2017 Jan 19. doi: 10.1371/journal.pone.0170282

PMCID:: PMC5245867

Abstract Article PDF–4.1M

Select item 37535435.

LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition

Jing Jin, Qian Yu, Chaofeng Han, Xiang Hu, Sheng Xu, Qingqing Wang, Jianli Wang, Nan Li, Xuetao Cao

Nat Commun. 2013 Aug 14; 4: 2075. Published online 2013 Aug 14. doi: 10.1038/ncomms3075

PMCID:: PMC3753543

Abstract Article PDF–850K

Select item 35894176.

14-3-3ε Mediates the Cell Fate Decision-Making Pathways in Response of Hepatocellular Carcinoma to Bleomycin-Induced DNA Damage

Siwei Tang, Huimin Bao, Yang Zhang, Jun Yao, Pengyuan Yang, Xian Chen

PLoS One. 2013; 8(3): e55268. Published online 2013 Mar 5. doi: 10.1371/journal.pone.0055268

PMCID:: PMC3589417

Abstract Article PDF–2.8M

Select item 96675867.

ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells

Zijie Gao, Jianye Xu, Yang Fan, Zongpu Zhang, Huizhi Wang, Mingyu Qian, Ping Zhang, Lin Deng, Jie Shen, Hao Xue, Rongrong Zhao, Teng Zhou, Xing Guo, Gang Li

J Exp Clin Cancer Res. 2022; 41: 323. Published online 2022 Nov 16. doi: 10.1186/s13046-022-02526-8

PMCID:: PMC9667586

Abstract Article PDF–11M

Select item 64645938.

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169

Vijay R. Menon, Varsha Ananthapadmanabhan, Selene Swanson, Siddharth Saini, Fatmata Sesay, Vasily Yakovlev, Laurence Florens, James A. DeCaprio, Michael P. Washburn, Mikhail Dozmorov, Larisa Litovchick

Cell Cycle. 2019; 18(5): 531–551. Published online 2019 Feb 17. doi: 10.1080/15384101.2019.1577525

PMCID:: PMC6464593

Abstract Article PDF–2.8M

Select item 90626599.

Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0

Fujun Hou, Zeyu Sun, Yue Deng, Siyu Chen, Xiyuan Yang, Feiyang Ji, Menghao Zhou, Keyi Ren, Dongli Pan

Front Microbiol. 2022; 13: 856471. Published online 2022 Apr 18. doi: 10.3389/fmicb.2022.856471

PMCID:: PMC9062659

Abstract Article PDF–3.5M

Select item 973393710.

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos

Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437

PMCID:: PMC9733937

Abstract Article PDF–2.2M

Select item 849618211.

Linking nuclear matrix–localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z

Zhaosu Chen, Yunpeng Zhang, Qingqing Guan, Huifang Zhang, Jing Luo, Jialun Li, Wei Wei, Xiang Xu, Lujian Liao, Jiemin Wong, Jiwen Li

J Biol Chem. 2021 Oct; 297(4): 101200. Published online 2021 Sep 17. doi: 10.1016/j.jbc.2021.101200

PMCID:: PMC8496182

Abstract Article PDF–5.8M

Select item 857430712.

Interactome profiling reveals interaction of SARS-CoV-2 NSP13 with host factor STAT1 to suppress interferon signaling

Kuan Feng, Yuan-Qin Min, Xiulian Sun, Fei Deng, Peiqing Li, Hualin Wang, Yun-Jia Ning

J Mol Cell Biol. 2021 Oct; 13(10): 760–762. Published online 2021 Oct 23. doi: 10.1093/jmcb/mjab068

PMCID:: PMC8574307

Article PDF–764K

Select item 562937213.

RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma

E Viziteu, B Klein, J Basbous, Y-L Lin, C Hirtz, C Gourzones, L Tiers, A Bruyer, L Vincent, C Grandmougin, A Seckinger, H Goldschmidt, A Constantinou, P Pasero, D Hose, J Moreaux

Leukemia. 2017 Oct; 31(10): 2104–2113. Prepublished online 2017 Feb 10. Published online 2017 Mar 10. doi: 10.1038/leu.2017.54

PMCID:: PMC5629372

Abstract Article PDF–2.9M

Select item 733229314.

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt M Kessler, John C Christianson

eLife. 2020; 9: e57306. Published online 2020 Jul 2. doi: 10.7554/eLife.57306

PMCID:: PMC7332293

Abstract Article PDF–2.2M

Select item 584947815.

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease

Graham F. Brady, Raymond Kwan, Peter J. Ulintz, Phirum Nguyen, Shirin Bassirian, Venkatesha Basrur, Alexey I. Nesvizhskii, Rohit Loomba, M. Bishr Omary

Hepatology. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Hepatology. 2018 May; 67(5): 1710–1725. Published online 2018 Mar 24. doi: 10.1002/hep.29522

PMCID:: PMC5849478

Abstract Article PDF–1.7M

Select item 754235616.

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells

Jaya Bhushan, Joshua B. Radke, Yi-Chieh Perng, Michael Mcallaster, Deborah J. Lenschow, Herbert W. Virgin, L. David Sibley

mBio. 2020 Sep-Oct; 11(5): e00852-20. Published online 2020 Oct 6. doi: 10.1128/mBio.00852-20

PMCID:: PMC7542356

Abstract Article PDF–2.4M

Select item 459714617.

Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases

Jun Yang, Yingxin Zhao, Mridul Kalita, Xueling Li, Mohammad Jamaluddin, Bing Tian, Chukwudi B. Edeh, John E. Wiktorowicz, Andrzej Kudlicki, Allan R. Brasier

Mol Cell Proteomics. 2015 Oct; 14(10): 2701–2721. Published online 2015 Jul 21. doi: 10.1074/mcp.M115.049221