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Select item 86674221.

Down-regulation of SOCS6: an unfavorable prognostic factor for gastrointestinal stromal tumor proven by survival analysis

Jun Ouyang, Tailai An, Yan Wang, Xiaofang Lu, Yawei Zhang, Xiaokun Wang, Xinhua Zhang, Changhua Zhang

Diagn Pathol. 2021; 16: 113. Published online 2021 Dec 12. doi: 10.1186/s13000-021-01172-6

PMCID:: PMC8667422

Abstract Article PDF–2.1M

Select item 32818472.

Array-Comparative Genomic Hybridization Reveals Loss of SOCS6 Is Associated with Poor Prognosis in Primary Lung Squamous Cell Carcinoma

Krishna B. Sriram, Jill E. Larsen, Santiyagu M. Savarimuthu Francis, Casey M. Wright, Belinda E. Clarke, Edwina E. Duhig, Kevin M. Brown, Nicholas K. Hayward, Ian A. Yang, Rayleen V. Bowman, Kwun M. Fong

PLoS One. 2012; 7(2): e30398. Published online 2012 Feb 17. doi: 10.1371/journal.pone.0030398

PMCID:: PMC3281847

Abstract Article PDF–1.2M

Select item 79537563.

SOCS6 promotes radiosensitivity and decreases cancer cell stemness in esophageal squamous cell carcinoma by regulating c-Kit ubiquitylation

Xuanzi Sun, Yuchen Sun, Jing Li, Xu Zhao, Xiaobo Shi, Tuotuo Gong, Shupei Pan, Zhongqiang Zheng, Xiaozhi Zhang

Cancer Cell Int. 2021; 21: 165. Published online 2021 Mar 12. doi: 10.1186/s12935-021-01859-2

PMCID:: PMC7953756

Abstract Article PDF–4.6M

Select item 60843184.

PTENP1 inhibits the growth of esophageal squamous cell carcinoma by regulating SOCS6 expression and correlates with disease prognosis

Tuotuo Gong, Shuyu Zheng, Shan Huang, Shenbo Fu, Xuanwei Zhang, Shupei Pan, Tian Yang, Yuchen Sun, Ya Wang, Beina Hui, Jia Guo, Xiaozhi Zhang

Mol Carcinog. 2017 Dec; 56(12): 2610–2619. Published online 2017 Aug 21. doi: 10.1002/mc.22705

PMCID:: PMC6084318

Abstract Article PDF–2.0M

Select item 54005915.

miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6

Sebastiano Rontauroli, Ruggiero Norfo, Valentina Pennucci, Roberta Zini, Samantha Ruberti, Elisa Bianchi, Simona Salati, Zelia Prudente, Chiara Rossi, Vittorio Rosti, Paola Guglielmelli, Giovanni Barosi, Alessandro Vannucchi, Enrico Tagliafico, Rossella Manfredini

Oncotarget. 2017 Mar 28; 8(13): 21380–21397. Published online 2017 Feb 9. doi: 10.18632/oncotarget.15226

PMCID:: PMC5400591

Abstract Article PDF–9.0M

Select item 42834046.

Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

Xin Hong, Hung Thanh Nguyen, Qingfeng Chen, Rui Zhang, Zandra Hagman, P Mathijs Voorhoeve, Stephen M Cohen

EMBO J. 2014 Nov 3; 33(21): 2447–2457. Published online 2014 Sep 1. doi: 10.15252/embj.201489385

PMCID:: PMC4283404

Abstract Article PDF–1.6M

Select item 41345067.

Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer

E Letellier, M Schmitz, K Baig, N Beaume, C Schwartz, S Frasquilho, L Antunes, N Marcon, P V Nazarov, L Vallar, J Even, S Haan

Br J Cancer. 2014 Aug 12; 111(4): 726–735. Published online 2014 Jul 15. doi: 10.1038/bjc.2014.377

PMCID:: PMC4134506

Abstract Article PDF–1.7M

Select item 35246478.

Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation

H-Y Lin, R-H Lai, S-T Lin, R-C Lin, M-J Wang, C-C Lin, H-C Lee, F-F Wang, J-Y Chen

Cell Death Differ. 2013 Jan; 20(1): 139–153. Published online 2012 Sep 7. doi: 10.1038/cdd.2012.106

PMCID:: PMC3524647

Abstract Article PDF–6.9M

Select item 78847779.

Circular RNA circ_103820 suppresses lung cancer tumorigenesis by sponging miR-200b-3p to release LATS2 and SOCS6

Yongbin Chi, Wenlong Zheng, Guangyu Bao, Lifeng Wu, Xiaoxue He, Ruyi Gan, Yan Shen, Xudong Yin, Mingming Jin

Cell Death Dis. 2021 Feb; 12(2): 185. Published online 2021 Feb 15. doi: 10.1038/s41419-021-03472-7

PMCID:: PMC7884777

Abstract Article PDF–3.4M

Select item 636863210.

miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC

Yang Xia, Ke Wei, Feng-Ming Yang, Liu-Qing Hu, Chun-Feng Pan, Xiang-Long Pan, Wei-Bing Wu, Jun Wang, Wei Wen, Zhi-Cheng He, Jing Xu, Xin-Feng Xu, Quan Zhu, Liang Chen

Cell Death Dis. 2019 Feb; 10(2): 112. Published online 2019 Feb 8. doi: 10.1038/s41419-019-1390-y

Correction in:: Cell Death Dis. 2020 Apr; 11(4): 261.

PMCID:: PMC6368632

Abstract Article PDF–3.7M

Select item 347631611.

Suppressor of Cytokine Signaling 6 (SOCS6) Negatively Regulates Flt3 Signal Transduction through Direct Binding to Phosphorylated Tyrosines 591 and 919 of Flt3

Julhash U. Kazi, Jianmin Sun, Bengt Phung, Fahad Zadjali, Amilcar Flores-Morales, Lars Rönnstrand

J Biol Chem. 2012 Oct 19; 287(43): 36509–36517. Published online 2012 Sep 5. doi: 10.1074/jbc.M112.376111

PMCID:: PMC3476316

Abstract Article PDF–1.6M

Select item 1082329012.

Extracellular vesicle‐encapsulated microRNA‐296‐3p from cancer‐associated fibroblasts promotes ovarian cancer development through regulation of the PTEN/AKT and SOCS6/STAT3 pathways

Luyao Sun, Miaola Ke, Mengyuan Yin, Ying Zeng, Yutong Ji, Yiming Hu, Songbin Fu, Chunyu Zhang

Cancer Sci. 2024 Jan; 115(1): 155–169. Published online 2023 Nov 16. doi: 10.1111/cas.16014

PMCID:: PMC10823290

Abstract Article PDF–25M

Select item 729834713.

miR-155-5p Implicates in the Pathogenesis of Renal Fibrosis via Targeting SOCS1 and SOCS6

Wanfen Zhang, Xiaoping Li, Yushang Tang, Cheng Chen, Ran Jing, Tongqiang Liu

Oxid Med Cell Longev. 2020; 2020: 6263921. Published online 2020 Jun 6. doi: 10.1155/2020/6263921

PMCID:: PMC7298347

Abstract Article PDF–2.1M

Select item 301300714.

Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin Ligase

Fahad Zadjali, Ashley C. W. Pike, Mattias Vesterlund, Jianmin Sun, Chenggang Wu, Shawn S. C. Li, Lars Rönnstrand, Stefan Knapp, Alex N. Bullock, Amilcar Flores-Morales

J Biol Chem. 2011 Jan 7; 286(1): 480–490. Published online 2010 Oct 28. doi: 10.1074/jbc.M110.173526

PMCID:: PMC3013007

Abstract Article PDF–2.7M

Select item 284417515.

SOCS-6 Negatively Regulates T Cell Activation through Targeting p56^lck to Proteasomal Degradation

Young Bong Choi, Myoungsun Son, Mijin Park, Jaekyoon Shin, Yungdae Yun

J Biol Chem. 2010 Mar 5; 285(10): 7271–7280. Published online 2009 Dec 10. doi: 10.1074/jbc.M109.073726

PMCID:: PMC2844175

Abstract Article PDF–1.4M

Select item 13390816.

SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation

Danielle L. Krebs, Rachel T. Uren, Donald Metcalf, Steven Rakar, Jian-Guo Zhang, Robyn Starr, David P. De Souza, Kathy Hanzinikolas, Jo Eyles, Lisa M. Connolly, Richard J. Simpson, Nicos A. Nicola, Sandra E. Nicholson, Manuel Baca, Douglas J. Hilton, Warren S. Alexander

Mol Cell Biol. 2002 Jul; 22(13): 4567–4578. doi: 10.1128/MCB.22.13.4567-4578.2002

PMCID:: PMC133908

Abstract Article PDF–350K

Select item 385151917.

Rbx2 regulates neuronal migration through different Cullin5-RING ligase adaptors

Sergi Simó, Jonathan A. Cooper

Dev Cell. Author manuscript; available in PMC 2014 Nov 25.

Published in final edited form as: Dev Cell. 2013 Nov 25; 27(4): 10.1016/j.devcel.2013.09.022. Published online 2013 Nov 7. doi: 10.1016/j.devcel.2013.09.022