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Items: 1 to 20 of 30

1.
Estrogen receptor α (ERα) indirectly induces transcription of human renal organic anion transporter 1 (OAT1)
Anna M. Euteneuer, Tamina Seeger‐Nukpezah, Hendrik Nolte, Maja Henjakovic
Physiol Rep. 2019 Nov; 7(21): e14229. Published online 2019 Nov 14. doi: 10.14814/phy2.14229
PMCID:
PMC6854606
AbstractArticlePDF–1.2M
2.
Linkage Disequilibrium Mapping of the Chromosome 6q21–22.31 Bipolar I Disorder Susceptibility Locus
Jinbo Fan, Iuliana Ionita-Laza, Matthew B. McQueen, Bernie Devlin, Shaun Purcell, Stephen V. Faraone, Michael H. Allen, Charles L. Bowden, Joseph R. Calabrese, Mark D. Fossey, Edward S. Friedman, Laszlo Gyulai, Peter Hauser, Terence B. Ketter, Lauren B. Marangell, David J. Miklowitz, Andrew A. Nierenberg, Jayendra K. Patel, Gary S. Sachs, Michael E. Thase, Francine B. Molay, Michael A. Escamilla, Vishwajit L. Nimgaonkar, Pamela Sklar, Nan M. Laird, Jordan W. Smoller
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2014 Jun 23.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5; 0(1): 29–37. doi: 10.1002/ajmg.b.30942
PMCID:
PMC4067321
AbstractArticlePDF–317K
3.
Three Ubiquitination Sites of Organic Anion Transporter-1 Synergistically Mediate Protein Kinase C–Dependent Endocytosis of the Transporter
Shanshan Li, Qiang Zhang, Guofeng You
Mol Pharmacol. 2013 Jul; 84(1): 139–146. Published online 2013 Jul. doi: 10.1124/mol.113.086769
PMCID:
PMC3684823
AbstractArticlePDF–1.2M
4.
Putative Transmembrane Domain 12 of the Human Organic Anion Transporter hOAT1 Determines Transporter Stability and Maturation Efficiency
Mei Hong, Shanshan Li, Fanfan Zhou, Paul E. Thomas, Guofeng You
J Pharmacol Exp Ther. 2010 Feb; 332(2): 650–658. doi: 10.1124/jpet.109.160515
PMCID:
PMC2812107
AbstractArticlePDF–1.6M
5.
Organic Anion Transporter OAT1 Undergoes Constitutive and Protein Kinase C-regulated Trafficking through a Dynamin- and Clathrin-dependent Pathway
Qiang Zhang, Mei Hong, Peng Duan, Zui Pan, Jianjie Ma, Guofeng You
J Biol Chem. 2008 Nov 21; 283(47): 32570–32579. doi: 10.1074/jbc.M800298200
PMCID:
PMC2583290
AbstractArticlePDF–739K
6.
A Three-dimensional Model of Human Organic Anion Transporter 1: AROMATIC AMINO ACIDS REQUIRED FOR SUBSTRATE TRANSPORT
Jennifer L. Perry, Neetu Dembla-Rajpal, Laura A. Hall, John B. Pritchard
J Biol Chem. Author manuscript; available in PMC 2007 Apr 2.
Published in final edited form as: J Biol Chem. 2006 Dec 8; 281(49): 38071–38079. Published online 2006 Oct 11. doi: 10.1074/jbc.M608834200
PMCID:
PMC1847411
AbstractArticlePDF–715K
7.
The kidney drug transporter OAT1 regulates gut microbiome–dependent host metabolism
Jeffry C. Granados, Vladimir Ermakov, Koustav Maity, David R. Vera, Geoffrey Chang, Sanjay K. Nigam
JCI Insight. 2023 Jan 24; 8(2): e160437. Published online 2023 Jan 24. doi: 10.1172/jci.insight.160437
PMCID:
PMC9977316
AbstractArticlePDF–5.9M
8.
Drug transporters OAT1 and OAT3 have specific effects on multiple organs and gut microbiome as revealed by contextualized metabolic network reconstructions
Neema Jamshidi, Sanjay K. Nigam
Sci Rep. 2022; 12: 18308. Published online 2022 Oct 31. doi: 10.1038/s41598-022-21091-w
PMCID:
PMC9622871
AbstractArticlePDF–6.0M
9.
Functional Characterization of Rare Variants in OAT1/SLC22A6 and OAT3/SLC22A8 Urate Transporters Identified in a Gout and Hyperuricemia Cohort
Jiří Vávra, Andrea Mančíková, Kateřina Pavelcová, Lenka Hasíková, Jana Bohatá, Blanka Stibůrková
Cells. 2022 Apr; 11(7): 1063. Published online 2022 Mar 22. doi: 10.3390/cells11071063
PMCID:
PMC8997829
AbstractArticlePDF–1.6M
10.
The Activity of Organic Anion Transporter-3: Role of Dexamethasone
Haoxun Wang, Chenchang Liu, Guofeng You
J Pharmacol Sci. Author manuscript; available in PMC 2021 Feb 5.
Published in final edited form as: J Pharmacol Sci. 2018 Feb; 136(2): 79–85. Published online 2018 Feb 2. doi: 10.1016/j.jphs.2017.12.011
PMCID:
PMC7864676
AbstractArticlePDF–1.1M
11.
Ubiquitin-specific Peptidase 8 Regulates the Trafficking and Stability of the Human Organic Anion Transporter 1
Jinghui Zhang, Chenchang Liu, Guofeng You
Biochim Biophys Acta Gen Subj. Author manuscript; available in PMC 2021 Feb 5.
Published in final edited form as: Biochim Biophys Acta Gen Subj. 2020 Dec; 1864(12): 129701. Published online 2020 Aug 17. doi: 10.1016/j.bbagen.2020.129701
PMCID:
PMC7863590
AbstractArticlePDF–1.4M
12.
Genetic Diversity in Drug Transporters: Impact in African Populations
Iris Rajman, Laura Knapp, Imad Hanna
Clin Transl Sci. 2020 Sep; 13(5): 848–860. Published online 2020 Mar 31. doi: 10.1111/cts.12769
Correction in:
Clin Transl Sci. 2022 Jan; 15(1): 287.
PMCID:
PMC7485953
AbstractArticlePDF–244K
13.
A novel SNP in the 5’ regulatory region of organic anion transporter 1 is associated with chronic kidney disease
Chiao-Yin Sun, Mai-Szu Wu, Chin-Chan Lee, Shu-Hong Chen, Kang-Chieh Lo, Yau-Hung Chen
Sci Rep. 2018; 8: 8085. Published online 2018 May 24. doi: 10.1038/s41598-018-26460-y
PMCID:
PMC5967335
AbstractArticlePDF–1.3M
14.
PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1
Da Xu, Jinghui Zhang, Qiang Zhang, Yunzhou Fan, Chenchang Liu, Guofeng You
Drug Metab Dispos. 2017 Aug; 45(8): 887–895. Published online 2017 Aug. doi: 10.1124/dmd.117.075861
PMCID:
PMC5506456
AbstractArticlePDF–1.6M
15.
Renal elimination of organic anions in cholestasis
Adriana Mónica Torres
World J Gastroenterol. 2008 Nov 21; 14(43): 6616–6621. Published online 2008 Nov 21. doi: 10.3748/wjg.14.6616
PMCID:
PMC2773300
AbstractArticlePDF–607K
16.
Nedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1
Da Xu, Haoxun Wang, Qiang Zhang, Guofeng You
Am J Physiol Renal Physiol. 2016 May 1; 310(9): F821–F831. Published online 2016 Jan 28. doi: 10.1152/ajprenal.00522.2015
PMCID:
PMC4867312
AbstractArticle
17.
Regulation of human organic anion transporter 1 by ANG II: involvement of protein kinase Cα
Shanshan Li, Peng Duan, Guofeng You
Am J Physiol Endocrinol Metab. 2009 Feb; 296(2): E378–E383. Published online 2008 Dec 16. doi: 10.1152/ajpendo.90713.2008
PMCID:
PMC2645019
AbstractArticle
18.
Population specific resequencing associates the ATP Binding Cassette Subfamily C Member 4 (ABCC4) gene with gout in New Zealand Maori and Pacific men
Callum Tanner, James Boocock, Eli A Stahl, Amanda Dobbyn, Asim K Mandal, Murray Cadzow, Amanda J Phipps-Green, Ruth K Topless, Jennie Harré Hindmarsh, Lisa K Stamp, Nicola Dalbeth, Hyon K Choi, David B Mount, Tony R Merriman
Arthritis Rheumatol. Author manuscript; available in PMC 2018 Jul 1.
Published in final edited form as: Arthritis Rheumatol. 2017 Jul; 69(7): 1461–1469. Published online 2017 May 31. doi: 10.1002/art.40110
PMCID:
PMC5984252
AbstractArticlePDF–554K
19.
Organic anion transporters, OAT1 and OAT3, are crucial biopterin transporters involved in bodily distribution of tetrahydrobiopterin and exclusion of its excess
Akiko Ohashi, Kaori Mamada, Tomonori Harada, Masako Naito, Tomihisa Takahashi, Shin Aizawa, Hiroyuki Hasegawa
Mol Cell Biochem. 2017; 435(1): 97–108. Published online 2017 May 22. doi: 10.1007/s11010-017-3060-7
PMCID:
PMC5632347
AbstractArticlePDF–548K
20.
The role of Nedd4-1 WW domains in binding and regulating human organic anion transporter 1
Da Xu, Haoxun Wang, Carol Gardner, Zui Pan, Ping L. Zhang, Jinghui Zhang, Guofeng You
Am J Physiol Renal Physiol. 2016 Aug 1; 311(2): F320–F329. Published online 2016 May 25. doi: 10.1152/ajprenal.00153.2016
PMCID:
PMC5243221
AbstractArticle

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