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Items: 1 to 20 of 31

1.
Leupaxin stimulates adhesion and migration of prostate cancer cells through modulation of the phosphorylation status of the actin-binding protein caldesmon
Sascha Dierks, Sandra von Hardenberg, Thomas Schmidt, Felix Bremmer, Peter Burfeind, Silke Kaulfuß
Oncotarget. 2015 May 30; 6(15): 13591–13606. Published online 2015 Apr 12. doi: 10.18632/oncotarget.3792
PMCID:
PMC4537036
AbstractArticlePDF–9.7M
2.
Leupaxin is expressed in mammary carcinoma and acts as a transcriptional activator of the estrogen receptor α
SILKE KAULFUSS, ANNA-MARIA HERR, ANJA BÜCHNER, BERNHARD HEMMERLEIN, ANDREAS R. GÜNTHERT, PETER BURFEIND
Int J Oncol. 2015 Jul; 47(1): 106–114. Published online 2015 May 6. doi: 10.3892/ijo.2015.2988
PMCID:
PMC4485646
AbstractArticlePDF–882K
3.
Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats
Murugendra S. Vanarotti, David B. Finkelstein, Cristina D. Guibao, Amanda Nourse, Darcie J. Miller, Jie J. Zheng
Biochemistry. 2016 Mar 8; 55(9): 1332–1345. Published online 2016 Feb 11. doi: 10.1021/acs.biochem.5b01274
PMCID:
PMC4843776
AbstractArticlePDF–6.0M
4.
Leupaxin is similar to paxillin in focal adhesion targeting and tyrosine phosphorylation but has distinct roles in cell adhesion and spreading
Pei-Wen Chen, Glenn S Kroog
Cell Adh Migr. 2010 Oct-Dec; 4(4): 527–540. doi: 10.4161/cam.4.4.12399
PMCID:
PMC3011259
AbstractArticlePDF–2.4M
5.
Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC
Mingyu Fang, Xu Liu, Wenbo Xu, Xing Wang, Lin Xu, Tong-jin Zhao, Peng Li, Hui Yang
J Biol Chem. 2024 Feb; 300(2): 105610. Published online 2023 Dec 28. doi: 10.1016/j.jbc.2023.105610
PMCID:
PMC10850781
AbstractArticlePDF–2.7M
6.
Leupaxin, a Novel Coactivator of the Androgen Receptor, Is Expressed in Prostate Cancer and Plays a Role in Adhesion and Invasion of Prostate Carcinoma Cells
Silke Kaulfuss, Michal Grzmil, Bernhard Hemmerlein, Paul Thelen, Stefan Schweyer, Jürgen Neesen, Lukas Bubendorf, Andrew G. Glass, Hubertus Jarry, Bernd Auber, Peter Burfeind
Mol Endocrinol. July 1, 2008; 22(7): 1606–1621. doi: 10.1210/me.2006-0546
PMCID:
PMC5419437
AbstractArticle
7.
GIT1 Utilizes a Focal Adhesion Targeting-Homology Domain to Bind Paxillin
Robert Schmalzigaug, Marie-Line Garron, J. Tyler Roseman, Yanghui Xing, Collin E. Davidson, Stefan T. Arold, Richard T. Premont
Cell Signal. Author manuscript; available in PMC 2008 Aug 1.
Published in final edited form as: Cell Signal. 2007 Aug; 19(8): 1733–1744. Published online 2007 Mar 30. doi: 10.1016/j.cellsig.2007.03.010
PMCID:
PMC2025689
AbstractArticlePDF–2.5M
8.
LIM domain‐containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin‐induced tyrosine phosphorylation of paxillin
Toshiyuki Tanaka, Kazumasa Moriwaki, Shinsuke Murata, Masayuki Miyasaka
Cancer Sci. 2010 Feb; 101(2): 363–368. Published online 2009 Oct 12. doi: 10.1111/j.1349-7006.2009.01398.x
PMCID:
PMC11158308
AbstractArticlePDF–546K
9.
The LIM protein, leupaxin, is enriched in smooth muscle and functions as an SRF-cofactor to induce smooth muscle cell gene transcription
Liisa J. Sundberg-Smith, Laura A. DiMichele, Rebecca L Thompson, Christopher P. Mack, Joan M. Taylor
Circ Res. Author manuscript; available in PMC 2009 Nov 30.
Published in final edited form as: Circ Res. 2008 Jun 20; 102(12): 1502–1511. Published online 2008 May 22. doi: 10.1161/CIRCRESAHA.107.170357
PMCID:
PMC2785029
AbstractArticlePDF–3.1M
10.
Susceptibility Loci Associated with Specific and Shared Subtypes of Lymphoid Malignancies
Joseph Vijai, Tomas Kirchhoff, Kasmintan A. Schrader, Jennifer Brown, Ana Virginia Dutra-Clarke, Christopher Manschreck, Nichole Hansen, Rohini Rau-Murthy, Kara Sarrel, Jennifer Przybylo, Sohela Shah, Srujana Cheguri, Zsofia Stadler, Liying Zhang, Ora Paltiel, Dina Ben-Yehuda, Agnes Viale, Carol Portlock, David Straus, Steven M. Lipkin, Mortimer Lacher, Mark Robson, Robert J. Klein, Andrew Zelenetz, Kenneth Offit
PLoS Genet. 2013 Jan; 9(1): e1003220. Published online 2013 Jan 17. doi: 10.1371/journal.pgen.1003220
PMCID:
PMC3547842
AbstractArticlePDF–1.4M
11.
Proteome-scale Binary Interactomics in Human Cells
Sam Lievens, José Van der Heyden, Delphine Masschaele, Leentje De Ceuninck, Ioanna Petta, Surya Gupta, Veronic De Puysseleyr, Virginie Vauthier, Irma Lemmens, Dries J. H. De Clercq, Dieter Defever, Nele Vanderroost, Anne-Sophie De Smet, Sven Eyckerman, Serge Van Calenbergh, Lennart Martens, Karolien De Bosscher, Claude Libert, David E. Hill, Marc Vidal, Jan Tavernier
Mol Cell Proteomics. 2016 Dec; 15(12): 3624–3639. Published online 2016 Nov 1. doi: 10.1074/mcp.M116.061994
PMCID:
PMC5141276
AbstractArticlePDF–1.5M
12.
Protein interactions of the transcription factor Hoxa1
Barbara Lambert, Julie Vandeputte, Sophie Remacle, Isabelle Bergiers, Nicolas Simonis, Jean-Claude Twizere, Marc Vidal, René Rezsohazy
BMC Dev Biol. 2012; 12: 29. Published online 2012 Oct 22. doi: 10.1186/1471-213X-12-29
PMCID:
PMC3514159
AbstractArticlePDF–1.6M
13.
Expanding the Substantial Interactome of NEMO Using Protein Microarrays
Beau J. Fenner, Michael Scannell, Jochen H. M. Prehn
PLoS One. 2010; 5(1): e8799. Published online 2010 Jan 20. doi: 10.1371/journal.pone.0008799
PMCID:
PMC2808332
AbstractArticlePDF–509K
14.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho
Nature. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582
PMCID:
PMC3491803
AbstractArticlePDF–706K
15.
Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism
Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva
Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650
Correction in:
Nat Commun. 2023; 14: 569.
PMCID:
PMC3996537
AbstractArticlePDF–1.9M
16.
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis
Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani
Oncogene. Author manuscript; available in PMC 2020 Sep 29.
Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9
PMCID:
PMC7523706
AbstractArticlePDF–2.3M
17.
Leveraging the power of next-generation sequencing to generate interactome datasets
Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal
Nat Methods. Author manuscript; available in PMC 2011 Dec 1.
Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597
PMCID:
PMC3188388
AbstractArticlePDF–932K
18.
Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions
Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano
Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604
PMCID:
PMC515316
AbstractArticlePDF–181K
19.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
20.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K

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