PMC Links for Gene (Select 9415) - PMC

Marika Colombo, Federico Passarelli, Paola A. Corsetto, Angela M. Rizzo, Mirko Marabese, Giulia De Simone, Roberta Pastorelli, Massimo Broggini, Laura Brunelli, Elisa Caiola

Cells. 2022 Dec; 11(23): 3719. Published online 2022 Nov 22. doi: 10.3390/cells11233719

PMCID:: PMC9736998

Abstract Article PDF–1.7M

Select item 92452414.

Interplay between fatty acid desaturase2 (FADS2) rs174583 genetic variant and dietary antioxidant capacity: cardio-metabolic risk factors in obese individuals

Mahdieh Khodarahmi, Parisa Javidzade, Mahdieh Abbasalizad Farhangi, Ahmad Hashemzehi, Houman Kahroba

BMC Endocr Disord. 2022; 22: 167. Published online 2022 Jun 30. doi: 10.1186/s12902-022-01075-7

PMCID:: PMC9245241

Abstract Article PDF–1.3M

Select item 89930485.

Lower polyunsaturated fatty acid levels and FADS2 expression in adult compared to neonatal keratinocytes are associated with FADS2 promotor hypermethylation

C. Pararasa, D.J. Messenger, K.E. Barrett, D. Hyliands, D. Talbot, M.I. Fowler, T. Kawatra, D.A. Gunn, F.L. Lim, L.J. Wainwright, G. Jenkins, H.R. Griffiths

Biochem Biophys Res Commun. 2022 Apr 23; 601: 9–15. doi: 10.1016/j.bbrc.2022.02.055

PMCID:: PMC8993048

Abstract Article

Select item 82223076.

Fatty acid desaturase 2 (FADS 2) rs174575 (C/G) polymorphism, circulating lipid levels and susceptibility to type-2 diabetes mellitus

Shilpa S. Shetty, N. Suchetha Kumari

Sci Rep. 2021; 11: 13151. Published online 2021 Jun 23. doi: 10.1038/s41598-021-92572-7

PMCID:: PMC8222307

Abstract Article PDF–1.0M

Select item 79095657.

Is There a FADS2-Modulated Link between Long-Chain Polyunsaturated Fatty Acids in Plasma Phospholipids and Polyphenol Intake in Adult Subjects Who Are Overweight?

Manja M. Zec, Irena Krga, Ljiljana Stojković, Maja Živković, Biljana Pokimica, Aleksandra Stanković, Maria Glibetic

Nutrients. 2021 Feb; 13(2): 296. Published online 2021 Jan 21. doi: 10.3390/nu13020296

PMCID:: PMC7909565

Abstract Article PDF–2.2M

Select item 76571488.

Delta‐6‐desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue

Marilla C. Pender‐Cudlip, Karen J. Krag, David Martini, Jeanne Yu, Anthony Guidi, Sandy S. Skinner, Yu Zhang, Xiying Qu, Chengwei He, Yi Xu, Steven Y. Qian, Jing X. Kang

Cancer Sci. 2013 Jun; 104(6): 760–764. Published online 2013 Mar 19. doi: 10.1111/cas.12129

PMCID:: PMC7657148

Abstract Article PDF–202K

Select item 75732009.

Seafood, Fatty Acid Biosynthesis Genes and Multiple Sclerosis Susceptibility

Annette Langer-Gould, Lucinda J Black, Emmanuelle Waubant, Jessica B Smith, Jun Wu, Edlin G Gonzales, Xiaorong Shao, Corinna Koebnick, Robyn M Lucas, Anny Xiang, Lisa F Barcellos

Mult Scler. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Mult Scler. 2020 Oct; 26(12): 1476–1485. Published online 2019 Sep 6. doi: 10.1177/1352458519872652

PMCID:: PMC7573200

Abstract Article PDF–145K

Select item 743737110.

CircFADS2: A potential prognostic biomarker of colorectal cancer

Yi-Sheng Xiao, Hua-Zhang Tong, Xi-Hong Yuan, Chang-Hui Xiong, Xiao-Yang Xu, Yuan-Feng Zeng

Exp Biol Med (Maywood) 2020 Aug; 245(14): 1233–1241. Published online 2020 Jun 2. doi: 10.1177/1535370220929965

PMCID:: PMC7437371

Abstract Article PDF–1015K

Select item 640485111.

Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of age

Colin D Steer, Eva Lattka, Berthold Koletzko, Jean Golding, Joseph R Hibbeln

Am J Clin Nutr. 2013 Dec; 98(6): 1575–1582. Published online 2013 Sep 25. doi: 10.3945/ajcn.112.051524

PMCID:: PMC6404851

Abstract Article PDF–97K

Select item 638030712.

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

Fernando Pires Hartwig, Neil Martin Davies, Bernardo Lessa Horta, Tarunveer S Ahluwalia, Hans Bisgaard, Klaus Bønnelykke, Avshalom Caspi, Terrie E Moffitt, Richie Poulton, Ayesha Sajjad, Henning W Tiemeier, Albert Dalmau-Bueno, Mònica Guxens, Mariona Bustamante, Loreto Santa-Marina, Nadine Parker, Tomáš Paus, Zdenka Pausova, Lotte Lauritzen, Theresia M Schnurr, Kim F Michaelsen, Torben Hansen, Wendy Oddy, Craig E Pennell, Nicole M Warrington, George Davey Smith, Cesar Gomes Victora

Int J Epidemiol. 2019 Feb; 48(1): 45–57. Published online 2018 Dec 11. doi: 10.1093/ije/dyy273

PMCID:: PMC6380307

Abstract Article PDF–729K

Select item 633780613.

Liver DNA methylation of FADS2 associates with FADS2 genotypex

Paula Walle, Ville Männistö, Vanessa Derenji de Mello, Maija Vaittinen, Alexander Perfilyev, Kati Hanhineva, Charlotte Ling, Jussi Pihlajamäki

Clin Epigenetics. 2019; 11: 10. Published online 2019 Jan 17. doi: 10.1186/s13148-019-0609-1

Correction in:: Clin Epigenetics. 2019; 11: 47.

PMCID:: PMC6337806

Abstract Article PDF–1017K

Select item 621829914.

A novel FADS2 isoform identified in human milk fat globule suppresses FADS2 mediated Δ6-desaturation of omega-3 fatty acids

Kumar S. D. Kothapalli, Hui Gyu Park, Xiaoxian Guo, Xuepeng Sun, James Zou, Stephanie S. Hyon, Xia Qin, Peter Lawrence, Rinat R. Ran-Ressler, Ji Yao Zhang, Zhenglong Gu, J. Thomas Brenna

Prostaglandins Leukot Essent Fatty Acids. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2018 Nov; 138: 52–59. Published online 2018 Jun 28. doi: 10.1016/j.plefa.2018.06.004

PMCID:: PMC6218299

Abstract Article PDF–801K

Select item 468933615.

FADS2 genotype regulates delta-6 desaturase activity and inflammation in human adipose tissue

Maija Vaittinen, Paula Walle, Emmi Kuosmanen, Ville Männistö, Pirjo Käkelä, Jyrki Ågren, Ursula Schwab, Jussi Pihlajamäki

J Lipid Res. 2016 Jan; 57(1): 56–65. doi: 10.1194/jlr.M059113

PMCID:: PMC4689336

Abstract Article PDF–1.1M

Select item 455036816.

The fatty acid desaturase 2 (FADS2) gene product catalyzes Δ4 desaturation to yield n-3 docosahexaenoic acid and n-6 docosapentaenoic acid in human cells

Hui Gyu Park, Woo Jung Park, Kumar S. D. Kothapalli, J. Thomas Brenna

FASEB J. 2015 Sep; 29(9): 3911–3919. Published online 2015 Jun 11. doi: 10.1096/fj.15-271783

PMCID:: PMC4550368

Abstract Article

Select item 428019117.

Loss of FADS2 Function Severely Impairs the Use of HeLa Cells as an In Vitro Model for Host Response Studies Involving Fatty Acid Effects

Anke Jaudszus, Christian Degen, Stephan W. Barth, Martin Klempt, Wiebke Schlörmann, Alexander Roth, Carsten Rohrer, Helga Sauerwein, Konrad Sachse, Gerhard Jahreis

PLoS One. 2014; 9(12): e115610. Published online 2014 Dec 30. doi: 10.1371/journal.pone.0115610

PMCID:: PMC4280191

Abstract Article PDF–899K

Select item 400481918.

Brain White Matter Development Is Associated with a Human-Specific Haplotype Increasing the Synthesis of Long Chain Fatty Acids

Bart D. Peters, Aristotle N. Voineskos, Philip R. Szeszko, Tristram A. Lett, Pamela DeRosse, Saurav Guha, Katherine H. Karlsgodt, Toshikazu Ikuta, Daniel Felsky, Majnu John, David J. Rotenberg, James L. Kennedy, Todd Lencz, Anil K. Malhotra

J Neurosci. 2014 Apr 30; 34(18): 6367–6376. doi: 10.1523/JNEUROSCI.2818-13.2014

PMCID:: PMC4004819

Abstract Article PDF–1.5M

Select item 364851419.

Genetic Variation in FADS Genes and Plasma Cholesterol Levels in 2-Year-Old Infants: KOALA Birth Cohort Study

Carolina Moltó-Puigmartí, Eugène Jansen, Joachim Heinrich, Marie Standl, Ronald P. Mensink, Jogchum Plat, John Penders, Monique Mommers, Gerard H. Koppelman, Dirkje S. Postma, Carel Thijs

PLoS One. 2013; 8(5): e61671. Published online 2013 May 8. doi: 10.1371/journal.pone.0061671

PMCID:: PMC3648514

Abstract Article PDF–390K

Select item 346569520.

Polyunsaturated fatty acid levels in blood during pregnancy, at birth and at 7 years: their associations with two common FADS2 polymorphisms

Colin D. Steer, Joseph R. Hibbeln, Jean Golding, George Davey Smith

Hum Mol Genet. 2012 Apr 1; 21(7): 1504–1512. Published online 2011 Dec 21. doi: 10.1093/hmg/ddr588

PMCID:: PMC3465695

Abstract Article PDF–240K

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