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Select item 110064711.

WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma

Qiankun Ji, Yazhou Guo, Zibo Li, Xiaoyang Zhang

Aging (Albany NY) 2024 Mar 31; 16(6): 5601–5617. Published online 2024 Mar 25. doi: 10.18632/aging.205666

PMCID:: PMC11006471

Abstract Article PDF–3.5M

Select item 94962642.

Role of WTAP in Cancer: From Mechanisms to the Therapeutic Potential

Yongfei Fan, Xinwei Li, Huihui Sun, Zhaojia Gao, Zheng Zhu, Kai Yuan

Biomolecules. 2022 Sep; 12(9): 1224. Published online 2022 Sep 2. doi: 10.3390/biom12091224

PMCID:: PMC9496264

Abstract Article PDF–2.0M

Select item 88306373.

Upregulated WTAP expression in colorectal cancer correlates with tumor site and differentiation

Xiao-Fang Dong, Yan Wang, Chih-Hsin Tang, Bi-Fei Huang, Zhang Du, Qian Wang, Jun-Kang Shao, Hua-Jun Lu, Chao-Qun Wang

PLoS One. 2022; 17(2): e0263749. Published online 2022 Feb 10. doi: 10.1371/journal.pone.0263749

PMCID:: PMC8830637

Abstract Article PDF–1.1M

Select item 77914564.

Gene Signatures and Prognostic Values of m6A RNA Methylation Regulators in Ovarian Cancer

Xiao Han, Jie Liu, Guomei Cheng, Shihong Cui

Cancer Control. 2020 Jan-Dec; 27(1): 1073274820960460. Published online 2020 Sep 21. doi: 10.1177/1073274820960460

PMCID:: PMC7791456

Abstract Article PDF–1.4M

Select item 76593285.

Expression and roles of Wilms' tumor 1‐associating protein in glioblastoma

Du‐Il Jin, Sang Weon Lee, Myoung‐Eun Han, Hyun‐Jung Kim, Seon‐Ae Seo, Gi‐Yeong Hur, Shin Jung, Bong‐Seon Kim, Sae‐Ock Oh

Cancer Sci. 2012 Dec; 103(12): 2102–2109. Published online 2012 Oct 22. doi: 10.1111/cas.12022

PMCID:: PMC7659328

Abstract Article PDF–997K

Select item 75283306.

Identification of WTAP-related genes by weighted gene co-expression network analysis in ovarian cancer

Jing Wang, Jing Xu, Ke Li, Yunke Huang, Yilin Dai, Congjian Xu, Yu Kang

J Ovarian Res. 2020; 13: 119. Published online 2020 Sep 30. doi: 10.1186/s13048-020-00710-y

PMCID:: PMC7528330

Abstract Article PDF–5.1M

Select item 74384897.

WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m⁶A-dependent manner

Shijie Chen, Yuezhan Li, Shuang Zhi, Zhiyu Ding, Weiguo Wang, Yi Peng, Yan Huang, Ruping Zheng, Haiyang Yu, Jianlong Wang, Minghua Hu, Jinglei Miao, Jinsong Li

Cell Death Dis. 2020 Aug; 11(8): 659. Published online 2020 Aug 19. doi: 10.1038/s41419-020-02847-6

PMCID:: PMC7438489

Abstract Article PDF–2.5M

Select item 71768778.

High expression of WTAP leads to poor prognosis of gastric cancer by influencing tumour‐associated T lymphocyte infiltration

Huafu Li, Qiao Su, Bo Li, Linxiang Lan, Chunming Wang, Wuguo Li, Gangqiang Wang, Wei Chen, Yulong He, Changhua Zhang

J Cell Mol Med. 2020 Apr; 24(8): 4452–4465. Published online 2020 Mar 16. doi: 10.1111/jcmm.15104

PMCID:: PMC7176877

Abstract Article PDF–2.8M

Select item 67045839.

WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1

Yunhao Chen, Chuanhui Peng, Junru Chen, Diyu Chen, Beng Yang, Bin He, Wendi Hu, Yanpeng Zhang, Hua Liu, Longfei Dai, Haiyang Xie, Lin Zhou, Jian Wu, Shusen Zheng

Mol Cancer. 2019; 18: 127. Published online 2019 Aug 22. doi: 10.1186/s12943-019-1053-8

PMCID:: PMC6704583

Abstract Article PDF–4.7M

Select item 582799310.

Wilms’ tumor 1-associating protein promotes renal cell carcinoma proliferation by regulating CDK2 mRNA stability

Jingyuan Tang, Feng Wang, Gong Cheng, Shuhui Si, Xi Sun, Jie Han, Hao Yu, Wei Zhang, Qiang Lv, Ji-Fu Wei, Haiwei Yang

J Exp Clin Cancer Res. 2018; 37: 40. Published online 2018 Feb 27. doi: 10.1186/s13046-018-0706-6

PMCID:: PMC5827993

Abstract Article PDF–3.9M

Select item 436979111.

WTAP is a novel oncogenic protein in acute myeloid leukemia

H Bansal, Q Yihua, SP Iyer, S Ganapathy, D Proia, LO Penalva, PJ Uren, U Suresh, JS Carew, AB Karnad, S Weitman, GE Tomlinson, MK Rao, SM Kornblau, S Bansal

Leukemia. Author manuscript; available in PMC 2015 Mar 23.

Published in final edited form as: Leukemia. 2014 May; 28(5): 1171–1174. Published online 2014 Jan 13. doi: 10.1038/leu.2014.16

Correction in:: volume 28 on page 2427

PMCID:: PMC4369791

Article PDF–689K

Select item 1083496112.

WTAP-mediated m⁶A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis

Xueying An, Rongliang Wang, Zhongyang Lv, Wenshu Wu, Ziying Sun, Rui Wu, Wenjin Yan, Qing Jiang, Xingquan Xu

Exp Mol Med. 2024 Feb; 56(1): 156–167. Published online 2024 Jan 4. doi: 10.1038/s12276-023-01135-5

PMCID:: PMC10834961

Abstract Article PDF–8.9M

Select item 1077409413.

甲基化酶WTAP通过调控FOXO1的表达参与肾缺血再灌注损伤

赵刚刚, 李华锋, 张鸿毅, 肖克兵, 杨辉, 李子峰, 傅崇德

Nan Fang Yi Ke Da Xue Xue Bao. 2023 Dec 20; 43(12): 2035–2042. Chinese. doi: 10.12122/j.issn.1673-4254.2023.12.07

PMCID:: PMC10774094

Abstract Article PDF–1.6M

Select item 1043523714.

A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression

Chaojun Yan, Jingjing Xiong, Zirui Zhou, Qifang Li, Chuan Gao, Mengyao Zhang, Liya Yu, Jinpeng Li, Ming-Ming Hu, Chen-Song Zhang, Cheguo Cai, Haojian Zhang, Jing Zhang

eLife. 2023; 12: RP87283. Published online 2023 Aug 17. doi: 10.7554/eLife.87283

PMCID:: PMC10435237

Abstract Article PDF–7.9M

Select item 1041651015.

N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progression

Zhaowei Lin, Tao Jiang, Wei Zheng, Jiayuan Zhang, Anan Li, Chao Lu, Wengang Liu

Cell Commun Signal. 2023; 21: 199. Published online 2023 Aug 10. doi: 10.1186/s12964-023-01228-8

PMCID:: PMC10416510

Abstract Article PDF–18M

Select item 984523916.

WTAP-mediated m⁶A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis

Yunhao You, Jincheng Liu, Lu Zhang, Xiang Li, Zhenqian Sun, Zihan Dai, Jinlong Ma, Guangjun Jiao, Yunzhen Chen

Cell Death Dis. 2023 Jan; 14(1): 33. Published online 2023 Jan 17. doi: 10.1038/s41419-023-05565-x

PMCID:: PMC9845239

Abstract Article PDF–7.2M

Select item 968300817.

WTAP Targets the METTL3 m⁶A-Methyltransferase Complex to Cytoplasmic Hepatitis C Virus RNA to Regulate Infection

Matthew T. Sacco, Katherine M. Bland, Stacy M. Horner

J Virol. 2022 Nov; 96(22): e00997-22. Published online 2022 Oct 31. doi: 10.1128/jvi.00997-22

PMCID:: PMC9683008

Abstract Article PDF–1.7M

Select item 966619718.

Potential impact of WTAP and YTHDF2 on tumor immunity in lung adenocarcinoma

Xinyu Zhang, Xinsheng Cai

Medicine (Baltimore) 2022 Nov 11; 101(45): e31195. Published online 2022 Nov 11. doi: 10.1097/MD.0000000000031195

PMCID:: PMC9666197

Abstract Article PDF–3.3M

Select item 935269919.

Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH)

Xinzhi Li, Kaixin Ding, Xueying Li, Bingchuan Yuan, Yuqin Wang, Zhicheng Yao, Shuaikang Wang, He Huang, Bolin Xu, Liwei Xie, Tuo Deng, Xiao-wei Chen, Zheng Chen

Nat Commun. 2022; 13: 4549. Published online 2022 Aug 4. doi: 10.1038/s41467-022-32163-w