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Select item 107836371.

RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks

Shubo Zhao, Jacqueline Cordes, Karolina M. Caban, Maximilian J. Götz, Timur Mackens-Kiani, Anthony J. Veltri, Niladri K. Sinha, Pedro Weickert, Selay Kaya, Graeme Hewitt, Danny D. Nedialkova, Thomas Fröhlich, Roland Beckmann, Allen R. Buskirk, Rachel Green, Julian Stingele

Mol Cell. 2023 Dec 7; 83(23): 4290–4303.e9. doi: 10.1016/j.molcel.2023.10.012

PMCID:: PMC10783637

Abstract Article

Select item 54279562.

The Von Hippel-Lindau Protein Suppresses Androgen Receptor Activity

Jing Wang, Wei Zhang, Wei Ji, Xing Liu, Gang Ouyang, Wuhan Xiao

Mol Endocrinol. 2014 Feb; 28(2): 239–248. Published online 2014 Jan 6. doi: 10.1210/me.2013-1258

PMCID:: PMC5427956

Abstract Article

Select item 51199913.

Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes

Sichen Shao, Jason Murray, Alan Brown, Jack Taunton, V. Ramakrishnan, Ramanujan S. Hegde

Cell. 2016 Nov 17; 167(5): 1229–1240.e15. doi: 10.1016/j.cell.2016.10.046

PMCID:: PMC5119991

Abstract Article

Select item 99944624.

An E3 ligase network engages GCN1 to promote degradation of translation factors on stalled ribosomes

Keely Oltion, Jordan D. Carelli, Tangpo Yang, Stephanie K. See, Hao-Yuan Wang, Martin Kampmann, Jack Taunton

Cell. Author manuscript; available in PMC 2024 Jan 19.

Published in final edited form as: Cell. 2023 Jan 19; 186(2): 346–362.e17. Published online 2023 Jan 12. doi: 10.1016/j.cell.2022.12.025

PMCID:: PMC9994462

Abstract Article PDF–2.4M

Select item 28489695.

Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination

Kexin Xu, Hermela Shimelis, Douglas E. Linn, Richeng Jiang, Xi Yang, Feng Sun, Zhiyong Guo, Hege Chen, Wei Li, Hegang Chen, Xiangtian Kong, Jonathan Melamed, Shengyun Fang, Zhen Xiao, Timothy D. Veenstra, Yun Qiu

Cancer Cell. Author manuscript; available in PMC 2010 Apr 7.

Published in final edited form as: Cancer Cell. 2009 Apr 7; 15(4): 270–282. doi: 10.1016/j.ccr.2009.02.021

PMCID:: PMC2848969

Abstract Article PDF–2.6M

Select item 36156546.

Ring Finger Protein 14 is a new regulator of TCF/β-catenin-mediated transcription and colon cancer cell survival

Beibei Wu, Sarah Piloto, Weihua Zeng, Nate P Hoverter, Thomas F Schilling, Marian L Waterman

EMBO Rep. 2013 Apr; 14(4): 347–355. Published online 2013 Mar 1. doi: 10.1038/embor.2013.19

PMCID:: PMC3615654

Abstract Article PDF–697K

Select item 1494677.

Electrostatic Modulation in Steroid Receptor Recruitment of LXXLL and FXXLF Motifs

Bin He, Elizabeth M. Wilson

Mol Cell Biol. 2003 Mar; 23(6): 2135–2150. doi: 10.1128/MCB.23.6.2135-2150.2003

PMCID:: PMC149467

Abstract Article PDF–1.2M

Select item 19515028.

Mammalian DET1 Regulates Cul4A Activity and Forms Stable Complexes with E2 Ubiquitin-Conjugating Enzymes

Elah Pick, On-Sun Lau, Tomohiko Tsuge, Suchithra Menon, Yingchun Tong, Naoshi Dohmae, Scott M. Plafker, Xing Wang Deng, Ning Wei

Mol Cell Biol. 2007 Jul; 27(13): 4708–4719. Published online 2007 Apr 23. doi: 10.1128/MCB.02432-06

PMCID:: PMC1951502

Abstract Article PDF–782K

Select item 5339909.

Negative Modulation of Androgen Receptor Transcriptional Activity by Daxx

Ding-Yen Lin, Hsin-I Fang, Ai-Hong Ma, Yen-Sung Huang, Yeong-Shiau Pu, Guido Jenster, Hsing-Jien Kung, Hsiu-Ming Shih

Mol Cell Biol. 2004 Dec; 24(24): 10529–10541. doi: 10.1128/MCB.24.24.10529-10541.2004

PMCID:: PMC533990

Abstract Article PDF–626K

Select item 352229510.

Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15

Sebastian D. Hayes, Han Liu, Ewan MacDonald, Christopher M. Sanderson, Judy M. Coulson, Michael J. Clague, Sylvie Urbé

J Biol Chem. 2012 Dec 14; 287(51): 43007–43018. Published online 2012 Oct 26. doi: 10.1074/jbc.M112.386938

PMCID:: PMC3522295

Abstract Article PDF–2.6M

Select item 273665211.

A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

Sjoerd J L van Wijk, Sjoerd J de Vries, Patrick Kemmeren, Anding Huang, Rolf Boelens, Alexandre M J J Bonvin, H Th Marc Timmers

Mol Syst Biol. 2009; 5: 295. Published online 2009 Aug 18. doi: 10.1038/msb.2009.55

Correction in:: Mol Syst Biol. 2009; 5: 317.

PMCID:: PMC2736652

Abstract Article PDF–5.6M

Select item 339495212.

Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks

Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson

Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162

PMCID:: PMC3394952

Abstract Article PDF–3.3M

Select item 276528013.

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

Gabriel Markson, Christina Kiel, Russell Hyde, Stephanie Brown, Panagoula Charalabous, Anja Bremm, Jennifer Semple, Jonathan Woodsmith, Simon Duley, Kourosh Salehi-Ashtiani, Marc Vidal, David Komander, Luis Serrano, Paul Lehner, Christopher M. Sanderson

Genome Res. 2009 Oct; 19(10): 1905–1911. doi: 10.1101/gr.093963.109

PMCID:: PMC2765280

Abstract Article PDF–425K

Select item 827099914.

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis

Rui Liu, Lin-Wen Zeng, Rong Gong, Fanen Yuan, Hong-Bing Shu, Shu Li

Nat Commun. 2021; 12: 4227. Published online 2021 Jul 9. doi: 10.1038/s41467-021-24321-3

PMCID:: PMC8270999

Abstract Article PDF–3.8M

Select item 44214815.

Functional Proteomics Mapping of a Human Signaling Pathway

Frédéric Colland, Xavier Jacq, Virginie Trouplin, Christelle Mougin, Caroline Groizeleau, Alexandre Hamburger, Alain Meil, Jérôme Wojcik, Pierre Legrain, Jean-Michel Gauthier

Genome Res. 2004 Jul; 14(7): 1324–1332. doi: 10.1101/gr.2334104

PMCID:: PMC442148

Abstract Article PDF–290K

Select item 406471816.

Charting the Landscape of Tandem BRCT Domain-Mediated Protein Interactions

Nicholas T. Woods, Rafael D. Mesquita, Michael Sweet, Marcelo A. Carvalho, Xueli Li, Yun Liu, Huey Nguyen, C. Eric Thomas, Edwin S. Iversen, Jr., Sylvia Marsillac, Rachel Karchin, John Koomen, Alvaro N.A. Monteiro

Sci Signal. Author manuscript; available in PMC 2014 Jun 20.

Published in final edited form as: Sci Signal. 2012; 5(242): rs6. Published online 2012 Sep 18. doi: 10.1126/scisignal.2002255

PMCID:: PMC4064718

Abstract Article PDF–2.1M

Select item 674264617.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 910523518.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 927928519.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 426658820.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

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