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Select item 110257311.

Expression of RAS and RAB interactor 1 (RIN1) in head and neck tumors at selected hospital in Ghana

Roland Osei Saahene, Precious Barnes, F. A. Yeboah, Elvis Agbo, Du-Bois Asante, Samuel Kofi Arhin

PLoS One. 2024; 19(4): e0301295. Published online 2024 Apr 18. doi: 10.1371/journal.pone.0301295

PMCID:: PMC11025731

Abstract Article PDF–1.3M

Select item 30460552.

A novel protein kinase D phosphorylation site in the tumor suppressor Rab interactor 1 is critical for coordination of cell migration

Susanne Ziegler, Tim Eiseler, Rolf-Peter Scholz, Alexander Beck, Gisela Link, Angelika Hausser

Mol Biol Cell. 2011 Mar 1; 22(5): 570–580. doi: 10.1091/mbc.E10-05-0427

PMCID:: PMC3046055

Abstract Article PDF–2.0M

Select item 29500633.

RIN1 is a Breast Tumor Suppressor Gene

Marc Milstein, Chelsea K. Mooser, Hailiang Hu, Marlena Fejzo, Dennis Slamon, Lee Goodglick, Sarah Dry, John Colicelli

Cancer Res. Author manuscript; available in PMC 2010 Oct 5.

Published in final edited form as: Cancer Res. 2007 Dec 15; 67(24): 11510–11516. doi: 10.1158/0008-5472.CAN-07-1147

PMCID:: PMC2950063

Abstract Article PDF–1.3M

Select item 81940984.

Role of RIN1 on telomerase activity driven by EGF-Ras mediated signaling in breast cancer

W. Zhang, M.L. Veisaga, M.A. Barbieri

Exp Cell Res. Author manuscript; available in PMC 2021 Nov 15.

Published in final edited form as: Exp Cell Res. 2020 Nov 15; 396(2): 112318. Published online 2020 Oct 16. doi: 10.1016/j.yexcr.2020.112318

PMCID:: PMC8194098

Abstract Article PDF–1.5M

Select item 55434685.

RIN1 promotes renal cell carcinoma malignancy by activating EGFR signaling through Rab25

Zi‐Hao Feng, Yong Fang, Liang‐Yun Zhao, Jun Lu, Yong‐Qian Wang, Zhen‐Hua Chen, Yong Huang, Jin‐Huan Wei, Yan‐Ping Liang, Jun‐Jie Cen, Yi‐Hui Pan, Bing Liao, Wei Chen, Jun‐Hang Luo

Cancer Sci. 2017 Aug; 108(8): 1620–1627. Published online 2017 Jul 3. doi: 10.1111/cas.13297

PMCID:: PMC5543468

Abstract Article PDF–2.0M

Select item 32575786.

FUNCTIONAL DETERMINANTS OF RAS INTERFERENCE 1 MUTANTS REQUIRED FOR THEIR INHBITORY ACTIVITY ON ENDOCYTOSIS

Adriana Galvis, Hugo Giambini, Zoilmar Villasana, M. Alejandro Barbieri

Exp Cell Res. Author manuscript; available in PMC 2012 Jan 13.

Published in final edited form as: Exp Cell Res. 2009 Mar 10; 315(5): 820–835. Published online 2008 Dec 16. doi: 10.1016/j.yexcr.2008.12.003

PMCID:: PMC3257578

Abstract Article PDF–3.2M

Select item 30498687.

ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1

M Thai, P Y Ting, J McLaughlin, D Cheng, M Müschen, O N Witte, J Colicelli

Leukemia. 2011 Feb; 25(2): 290–300. Published online 2010 Nov 19. doi: 10.1038/leu.2010.268

PMCID:: PMC3049868

Abstract Article PDF–785K

Select item 27853218.

Cell Proliferation and Epidermal Growth Factor Signaling in Non-small Cell Lung Adenocarcinoma Cell Lines Are Dependent on Rin1

Jin C. Tomshine, Sandra R. Severson, Dennis A. Wigle, Zhifu Sun, Daniah A. T. Beleford, Vijayalakshmi Shridhar, Bruce F. Horazdovsky

J Biol Chem. 2009 Sep 25; 284(39): 26331–26339. Published online 2009 Jul 1. doi: 10.1074/jbc.M109.033514

PMCID:: PMC2785321

Abstract Article PDF–2.7M

Select item 27618169.

Inhibition of Early Endosome Fusion by RAB5 - Binding Defective RAS Interference 1 Mutants

Adriana Galvis, Valeria Balmaceda, Hugo Giambini, Alejandro Conde, Zoilmar Villasana, Miguel W. Fornes, M. Alejandro Barbieri

Arch Biochem Biophys. Author manuscript; available in PMC 2009 Oct 14.

Published in final edited form as: Arch Biochem Biophys. 2009 Feb; 482(1-2): 83–95. Published online 2008 Nov 14. doi: 10.1016/j.abb.2008.11.009

PMCID:: PMC2761816

Abstract Article PDF–1.1M

Select item 674193610.

The RAS Effector RIN1 Modulates the Formation of Aversive Memories

Ajay Dhaka, Rui M. Costa, Hailiang Hu, Dwain K. Irvin, Apoor Patel, Harley I. Kornblum, Alcino J. Silva, Thomas J. O'Dell, John Colicelli

J Neurosci. 2003 Feb 1; 23(3): 748–757. doi: 10.1523/JNEUROSCI.23-03-00748.2003

PMCID:: PMC6741936

Abstract Article PDF–498K

Select item 487716411.

Activation of mitofusin2 by Smad2-RIN1 complex during mitochondrial fusion

Sanjay Kumar, Christopher C. Pan, Nirav Shah, Sarah E. Wheeler, Kari R. Hoyt, Nadine Hempel, Karthikeyan Mythreye, Nam Y. Lee

Mol Cell. Author manuscript; available in PMC 2017 May 19.

Published in final edited form as: Mol Cell. 2016 May 19; 62(4): 520–531. Published online 2016 May 12. doi: 10.1016/j.molcel.2016.04.010

PMCID:: PMC4877164

Abstract Article PDF–691K

Select item 13355612.

The RAS Effector RIN1 Directly Competes with RAF and Is Regulated by 14-3-3 Proteins

Ying Wang, Richard T. Waldron, Ajay Dhaka, Apoor Patel, Maggie M. Riley, Enrique Rozengurt, John Colicelli

Mol Cell Biol. 2002 Feb; 22(3): 916–926. doi: 10.1128/MCB.22.3.916-926.2001

PMCID:: PMC133556

Abstract Article PDF–560K

Select item 23035513.

A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1.

L Han, J Colicelli

Mol Cell Biol. 1995 Mar; 15(3): 1318–1323. doi: 10.1128/mcb.15.3.1318

PMCID:: PMC230355

Summary PDF–766K

Select item 5135014.

Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae.

J Colicelli, C Nicolette, C Birchmeier, L Rodgers, M Riggs, M Wigler

Proc Natl Acad Sci U S A. 1991 Apr 1; 88(7): 2913–2917. doi: 10.1073/pnas.88.7.2913

PMCID:: PMC51350

Summary Page Browse PDF–1.1M

Select item 357571515.

RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR

Kavitha Balaji, Chelsea Mooser, Christine M. Janson, Joanne M. Bliss, Houmehr Hojjat, John Colicelli

J Cell Sci. 2012 Dec 1; 125(23): 5887–5896. doi: 10.1242/jcs.113688

PMCID:: PMC3575715

Abstract Article

Select item 2461216.

Protein binding and signaling properties of RIN1 suggest a unique effector function

Limin Han, Derrick Wong, Ajay Dhaka, Daniel Afar, Michael White, Wielin Xie, Harvey Herschman, Owen Witte, John Colicelli

Proc Natl Acad Sci U S A. 1997 May 13; 94(10): 4954–4959. doi: 10.1073/pnas.94.10.4954

PMCID:: PMC24612

Abstract Article PDF–346K

Select item 549375517.

Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein

Laura A. Laviolette, Julien Mermoud, Isabel A. Calvo, Nicholas Olson, Myriam Boukhali, Ortrud K. Steinlein, Elisabeth Roider, Elke C. Sattler, Dachuan Huang, Bin Tean Teh, Mo Motamedi, Wilhelm Haas, Othon Iliopoulos

Nat Commun. 2017; 8: 15866. Published online 2017 Jun 28. doi: 10.1038/ncomms15866

PMCID:: PMC5493755

Abstract Article PDF–2.4M

Select item 873228218.

Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer

Chune Yu, Dan Luo, Jing Yu, Min Zhang, Xiaobo Zheng, Guangchao Xu, Jiaxin Wang, Huiling Wang, Yufei Xu, Ke Jiang, Jie Xu, Xuelei Ma, Jing Jing, Hubing Shi

Oncogene. 2022; 41(2): 191–203. Published online 2021 Oct 30. doi: 10.1038/s41388-021-02077-w

PMCID:: PMC8732282

Abstract Article PDF–6.3M

Select item 270004819.

Identification of Novel Smad2 and Smad3 Associated Proteins in Response to TGF-β1

Kimberly A. Brown, Amy-Joan L. Ham, Cara N. Clark, Nahum Meller, Brian K. Law, Anna Chytil, Nikki Cheng, Jennifer A. Pietenpol, Harold L. Moses

J Cell Biochem. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: J Cell Biochem. 2008 Oct 1; 105(2): 596–611. doi: 10.1002/jcb.21860

PMCID:: PMC2700048

Abstract Article PDF–1.1M

Select item 900533220.

A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity

Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez-Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan

Science. Author manuscript; available in PMC 2022 Apr 13.

Published in final edited form as: Science. 2021 Oct; 374(6563): eabf2911. Published online 2021 Oct 1. doi: 10.1126/science.abf2911

PMCID:: PMC9005332

Abstract Article PDF–2.0M

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