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Select item 93597461.

Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer

Mingjie An, Hanhao Zheng, Jian Huang, Yan Lin, Yuming Luo, Yao Kong, Mingrui Pang, Dingwen Zhang, Jiabin Yang, Jiancheng Chen, Yuanlong Li, Changhao Chen, Tianxin Lin

Cancer Res. 2022 Jun 15; 82(12): 2239–2253. Published online 2022 Apr 8. doi: 10.1158/0008-5472.CAN-21-4349

PMCID:: PMC9359746

Abstract Article PDF–3.1M

Select item 84902372.

Nuclear receptor corepressor (NCoR) is a positive prognosticator for cervical cancer

Daniel Beilner, Christina Kuhn, Bernd P. Kost, Theresa Vilsmaier, Aurelia Vattai, Till Kaltofen, Sven Mahner, Elisa Schmoeckel, Christian Dannecker, Julia Jückstock, Doris Mayr, Udo Jeschke, Helene Hildegard Heidegger

Arch Gynecol Obstet. 2021; 304(5): 1307–1314. Published online 2021 Apr 16. doi: 10.1007/s00404-021-06053-3

PMCID:: PMC8490237

Abstract Article PDF–1.0M

Select item 77140813.

NCOR1 may be a potential biomarker of a novel molecular subtype of prostate cancer

Lu Tang, Lixia Zhang, Lei Liu, Liping Dong, Yuan Dong, Wenhe Zhu, Huiyan Wang

FEBS Open Bio. 2020 Dec; 10(12): 2678–2686. Published online 2020 Nov 8. doi: 10.1002/2211-5463.13004

PMCID:: PMC7714081

Abstract Article PDF–1.0M

Select item 62615934.

Evaluation of transcriptionally regulated genes identifies NCOR1 in hormone receptor negative breast tumors and lung adenocarcinomas as a potential tumor suppressor gene

María del Mar Noblejas-López, Sara Morcillo-García, Cristina Nieto-Jiménez, Miriam Nuncia-Cantarero, Balázs Győrffy, Eva M. Galan-Moya, Atanasio Pandiella, Alberto Ocaña

PLoS One. 2018; 13(11): e0207776. Published online 2018 Nov 28. doi: 10.1371/journal.pone.0207776

PMCID:: PMC6261593

Abstract Article PDF–2.4M

Select item 49709195.

Nuclear Receptor Corepressor 1 expression and output declines with prostate cancer progression

Sandra M. Lopez, Alexander I. Agoulnik, Manqi Zhang, Leif E. Peterson, Egla Suarez, Gregory A. Gandarillas, Anna Frolov, Rile Li, Kimal Rajapakshe, Christian Coarfa, Michael M. Ittmann, Nancy L. Weigel, Irina U. Agoulnik

Clin Cancer Res. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Clin Cancer Res. 2016 Aug 1; 22(15): 3937–3949. Published online 2016 Mar 11. doi: 10.1158/1078-0432.CCR-15-1983

PMCID:: PMC4970919

Abstract Article PDF–1.8M

Select item 47254846.

Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis

Olaia A. Martínez-Iglesias, Elvira Alonso-Merino, Sara Gómez-Rey, Juan Pedro Velasco-Martín, Rosa Martín Orozco, Enrique Luengo, Rosa García Martín, Inmaculada Ibáñez de Cáceres, Agustín F. Fernández, Mario F. Fraga, Pilar González-Peramato, Constantino Varona, José Palacios, Javier Regadera, Ana Aranda

Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3): E328–E337. Published online 2016 Jan 4. doi: 10.1073/pnas.1520469113

PMCID:: PMC4725484

Abstract Article PDF–2.0M

Select item 44962177.

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance

Fernando Gallardo, Andreina Padrón, Ricard Garcia-Carbonell, Cristina Rius, Abel González-Perez, Montserrat Arumí-Uria, Mar Iglesias, Lara Nonell, Beatriz Bellosillo, Sonia Segura, Ramon Maria Pujol, Nuria Lopez-Bigas, Joan Bertran, Anna Bigas, Lluís Espinosa

Oncotarget. 2015 Apr 20; 6(11): 9284–9294. Published online 2015 Mar 19. doi: 10.18632/oncotarget.3252

PMCID:: PMC4496217

Abstract Article PDF–3.9M

Select item 38953878.

NCoR controls glioblastoma tumor cell characteristics

Nina Heldring, Ulrika Nyman, Peter Lönnerberg, Sofie Önnestam, Anna Herland, Johan Holmberg,, Ola Hermanson

Neuro Oncol. 2014 Jan; 16(2): 241–249. Published online 2013 Dec 12. doi: 10.1093/neuonc/not214

PMCID:: PMC3895387

Abstract Article PDF–1.2M

Select item 37339159.

Akt-Induced Phosphorylation of N-CoR at Serine 1450 Contributes to Its Misfolded Conformational Dependent Loss (MCDL) in Acute Myeloid Leukemia of the M5 Subtype

Dawn Sijin Nin, Azhar Bin Ali, Koichi Okumura, Norio Asou, Chien-Shing Chen, Wee Joo Chng, Matiullah Khan

PLoS One. 2013; 8(8): e70891. Published online 2013 Aug 5. doi: 10.1371/journal.pone.0070891

PMCID:: PMC3733915

Abstract Article PDF–1.2M

Select item 317950910.

Role of Chaperone Mediated Autophagy (CMA) in the Degradation of Misfolded N-CoR Protein in Non-Small Cell Lung Cancer (NSCLC) Cells

Azhar Bin Ali, Dawn Sijin Nin, John Tam, Matiullah Khan

PLoS One. 2011; 6(9): e25268. Published online 2011 Sep 23. doi: 10.1371/journal.pone.0025268

PMCID:: PMC3179509

Abstract Article PDF–600K

Select item 293080011.

Elevated NCOR1 disrupts PPARα/γ signaling in prostate cancer and forms a targetable epigenetic lesion

Sebastiano Battaglia, Orla Maguire, James L. Thorne, Laura B. Hornung, Craig L. Doig, Song Liu, Lara E. Sucheston, Anna Bianchi, Farhat L. Khanim, Lyndon M. Gommersall, Henry S.O. Coulter, Serena Rakha, Ian Giddings, Laura P. O'Neill, Colin S. Cooper, Christopher J. McCabe, Christopher M. Bunce, Moray J. Campbell

Carcinogenesis. 2010 Sep; 31(9): 1650–1660. Published online 2010 May 13. doi: 10.1093/carcin/bgq086

PMCID:: PMC2930800

Abstract Article PDF–676K

Select item 286374312.

NCoR1 Mediates Papillomavirus E8^E2C Transcriptional Repression

Maria L. C. Powell, Jennifer A. Smith, Mathew E. Sowa, J. Wade Harper, Thomas Iftner, Frank Stubenrauch, Peter M. Howley

J Virol. 2010 May; 84(9): 4451–4460. Published online 2010 Feb 24. doi: 10.1128/JVI.02390-09

PMCID:: PMC2863743

Abstract Article PDF–1.6M

Select item 272215213.

Elevated NCOR1 disrupts a network of dietary-sensing nuclear receptors in bladder cancer cells

S. Asad Abedin, James L. Thorne, Sebastiano Battaglia, Orla Maguire, Laura B. Hornung, Alan P. Doherty, Ian G. Mills, Moray J. Campbell

Carcinogenesis. 2009 Mar; 30(3): 449–456. Published online 2009 Jan 6. doi: 10.1093/carcin/bgp005

PMCID:: PMC2722152

Abstract Article PDF–454K

Select item 23211414.

Nuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormone.

T Tagami, L D Madison, T Nagaya, J L Jameson

Mol Cell Biol. 1997 May; 17(5): 2642–2648. doi: 10.1128/mcb.17.5.2642

PMCID:: PMC232114

Summary PDF–379K

Select item 2798615.

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

Jianxiang Wang, Taizo Hoshino, Robert L. Redner, Sachiko Kajigaya, Johnson M. Liu

Proc Natl Acad Sci U S A. 1998 Sep 1; 95(18): 10860–10865. doi: 10.1073/pnas.95.18.10860

PMCID:: PMC27986

Abstract Article PDF–296K

Select item 980425016.

NCoR1 controls immune tolerance in conventional dendritic cells by fine-tuning glycolysis and fatty acid oxidation

Kaushik Sen, Rashmirekha Pati, Atimukta Jha, Gyan Prakash Mishra, Subhasish Prusty, Shweta Chaudhary, Swati Swetalika, Sreeparna Podder, Aishwarya Sen, Mamuni Swain, Ranjan Kumar Nanda, Sunil K. Raghav

Redox Biol. 2023 Feb; 59: 102575. Published online 2022 Dec 16. doi: 10.1016/j.redox.2022.102575

PMCID:: PMC9804250

Abstract Article PDF–14M

Select item 799284517.

Discovery of LAMP-2A as potential biomarkers for glioblastoma development by modulating apoptosis through N-CoR degradation

Yongjie Wang, Buyi Zhang, Jianli Wang, Haijian Wu, Shenbin Xu, Jianmin Zhang, Lin Wang

Cell Commun Signal. 2021; 19: 40. Published online 2021 Mar 24. doi: 10.1186/s12964-021-00729-8

PMCID:: PMC7992845

Abstract Article PDF–9.1M

Select item 691115618.

Abnormally localized DLK1 interacts with NCOR1 in non-small cell lung cancer cell nuclear

Jinjing Tan, Susu Zhang, Lin Li, Jing Mu, Ziyu Wang, Lina Zhang, Mei Jiang, Weiying Li, Xin Yang, Yu Liu, Yanning Gao

Biosci Rep. 2019 Dec 20; 39(12): BSR20192362. Published online 2019 Dec 13. doi: 10.1042/BSR20192362

PMCID:: PMC6911156

Abstract Article PDF–3.4M

Select item 658047619.

Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals

Martin L. Privalsky, Michael L. Goodson

BMC Res Notes. 2019; 12: 343. Published online 2019 Jun 17. doi: 10.1186/s13104-019-4384-z

PMCID:: PMC6580476

Abstract Article PDF–1.1M

Select item 597424620.

Whole-exome sequence analysis highlights the role of unmasked recessive mutations in copy number variants with incomplete penetrance

Matthieu Egloff, Lam-Son Nguyen, Karine Siquier-Pernet, Valérie Cormier-Daire, Geneviève Baujat, Tania Attié-Bitach, Christine Bole-Feysot, Patrick Nitschke, Michel Vekemans, Laurence Colleaux, Valérie Malan

Eur J Hum Genet. 2018 Jun; 26(6): 912–918. Published online 2018 Feb 26. doi: 10.1038/s41431-018-0124-4

PMCID:: PMC5974246

Abstract Article PDF–1.7M

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PMC Links for Gene (Select 9611) (231)
PMC
Homo sapiens CXADR Ig-like cell adhesion molecule (CXADR), transcript variant 1,...
Homo sapiens CXADR Ig-like cell adhesion molecule (CXADR), transcript variant 1, mRNA
gi|1519244247|ref|NM_001338.5|

Nucleotide
PREDICTED: Homo sapiens nuclear receptor corepressor 1 (NCOR1), transcript varia...
PREDICTED: Homo sapiens nuclear receptor corepressor 1 (NCOR1), transcript variant X5, mRNA
gi|2217314936|ref|XM_005256868.6|

Nucleotide
PREDICTED: Homo sapiens nuclear receptor corepressor 1 (NCOR1), transcript varia...
PREDICTED: Homo sapiens nuclear receptor corepressor 1 (NCOR1), transcript variant X36, mRNA
gi|2462559074|ref|XM_054317944.1|

Nucleotide
ZC3H15 zinc finger CCCH-type containing 15 [Homo sapiens]
ZC3H15 zinc finger CCCH-type containing 15 [Homo sapiens]
Gene ID:55854

Gene

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