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Select item 53595391.

Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women

Megan Hardin, Michael H. Cho, Sunita Sharma, Kimberly Glass, Peter J. Castaldi, Merry-Lynn McDonald, Hugues Aschard, Jody Senter-Sylvia, Kelan Tantisira, Scott T. Weiss, Craig P. Hersh, Jarrett D. Morrow, David Lomas, Alvar Agusti, Per Bakke, Amund Gulsvik, George T. O’Connor, Josée Dupuis, John Hokanson, James D. Crapo, Terri H. Beaty, Nan Laird, Edwin K. Silverman, Dawn L. DeMeo

Am J Respir Cell Mol Biol. 2017 Mar; 56(3): 332–341. doi: 10.1165/rcmb.2016-0172OC

PMCID:: PMC5359539

Abstract Article PDF–1.0M

Select item 39548902.

Identification of Novel CELSR1 Mutations in Spina Bifida

Yunping Lei, Huiping Zhu, Wei Yang, M. Elizabeth Ross, Gary M. Shaw, Richard H. Finnell

PLoS One. 2014; 9(3): e92207. Published online 2014 Mar 14. doi: 10.1371/journal.pone.0092207

PMCID:: PMC3954890

Abstract Article PDF–1.5M

Select item 37145943.

Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis

Florence Tatin, Andrea Taddei, Anne Weston, Elaine Fuchs, Danelle Devenport, Fadel Tissir, Taija Makinen

Dev Cell. 2013 Jul 15; 26(1): 31–44. doi: 10.1016/j.devcel.2013.05.015

PMCID:: PMC3714594

Abstract Article

Select item 70728804.

CELSR1 Promotes Neuroprotection in Cerebral Ischemic Injury Mainly through the Wnt/PKC Signaling Pathway

Li-Hong Wang, Geng-Lin Zhang, Xing-Yu Liu, Ai Peng, Hai-Yuan Ren, Shu-Hong Huang, Ting Liu, Xiao-Jing Wang

Int J Mol Sci. 2020 Feb; 21(4): 1267. Published online 2020 Feb 13. doi: 10.3390/ijms21041267

PMCID:: PMC7072880

Abstract Article PDF–8.0M

Select item 65282825.

Genetics of heart rate in heart failure patients (GenHRate)

Kaleigh L. Evans, Heidi S. Wirtz, Jia Li, Ruicong She, Juan Maya, Hongsheng Gui, Andrew Hamer, Christophe Depre, David E. Lanfear

Hum Genomics. 2019; 13: 22. Published online 2019 May 21. doi: 10.1186/s40246-019-0206-6

PMCID:: PMC6528282

Abstract Article PDF–1.4M

Select item 74870406.

Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects

Tian Tian, Yunping Lei, Yongyan Chen, Menuka Karki, Lei Jin, Richard H. Finnell, Linlin Wang, Aiguo Ren

Hum Genet. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Hum Genet. 2020 Oct; 139(10): 1299–1314. Published online 2020 Apr 30. doi: 10.1007/s00439-020-02172-0

PMCID:: PMC7487040

Abstract Article PDF–1.5M

Select item 73464597.

circCELSR1 facilitates ovarian cancer proliferation and metastasis by sponging miR-598 to activate BRD4 signals

Xiang-Yang Zeng, Jing Yuan, Chen Wang, Da Zeng, Jia-Hui Yong, Xiao-Yan Jiang, Hua Lan, Song-Shu Xiao

Mol Med. 2020; 26: 70. Published online 2020 Jul 8. doi: 10.1186/s10020-020-00194-y

PMCID:: PMC7346459

Abstract Article PDF–3.7M

Select item 47721238.

Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect, craniorachischisis

Alexis Robinson, Sarah Escuin, Kit Doudney, Michel Vekemans, Roger E Stevenson, Nicholas DE Greene, Andrew J Copp, Philip Stanier

Hum Mutat. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: Hum Mutat. 2012 Feb; 33(2): 440–447. Published online 2011 Dec 20. doi: 10.1002/humu.21662

PMCID:: PMC4772123

Abstract Article PDF–1.4M

Select item 105924769.

The adhesion GPCRs CELSR1–3 and LPHN3 engage G proteins via distinct activation mechanisms

Duy Lan Huong Bui, Andrew Roach, Jingxian Li, Sumit J. Bandekar, Elizabeth Orput, Ritika Raghavan, Demet Araç, Richard C. Sando

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112552. Published online 2023 May 23. doi: 10.1016/j.celrep.2023.112552

PMCID:: PMC10592476

Abstract Article PDF–4.9M

Select item 512609610.

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

Hortensja Ł. Brzóska, Angela M. d’Esposito, Maria Kolatsi-Joannou, Vishal Patel, Peter Igarashi, Yunping Lei, Richard H. Finnell, Mark F. Lythgoe, Adrian S. Woolf, Eugenia Papakrivopoulou, David A. Long

Kidney Int. 2016 Dec; 90(6): 1274–1284. doi: 10.1016/j.kint.2016.07.011

PMCID:: PMC5126096

Abstract Article

Select item 286537811.

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

Laura L. Yates, Carsten Schnatwinkel, Jennifer N. Murdoch, Debora Bogani, Caroline J. Formstone, Stuart Townsend, Andy Greenfield, Lee A. Niswander, Charlotte H. Dean

Hum Mol Genet. 2010 Jun 1; 19(11): 2251–2267. Published online 2010 Mar 10. doi: 10.1093/hmg/ddq104

PMCID:: PMC2865378

Abstract Article PDF–1.0M

Select item 317112312.

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

Jason D. Berndt, Atsushi Aoyagi, Peitzu Yang, Jamie N. Anastas, Lan Tang, Randall T. Moon

J Cell Biol. 2011 Sep 5; 194(5): 737–750. doi: 10.1083/jcb.201107021

PMCID:: PMC3171123

Abstract Article PDF–3.3M

Select item 1620313.

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes

Qiang Wu, Tom Maniatis

Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7): 3124–3129. Published online 2000 Mar 14. doi: 10.1073/pnas.060027397

PMCID:: PMC16203

Abstract Article PDF–254K

Select item 856647314.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 926261415.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 923162316.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 674682217.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

Select item 567858118.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 582692619.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 289646420.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

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