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Select item 110289201.

Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients

Ray Wilkinson, Katherine Woods, Rachael D’Rozario, Rebecca Prue, Frank Vari, Melinda Y. Hardy, Ying Dong, Judith A. Clements, Derek N. J. Hart, Kristen J. Radford

Cancer Immunol Immunother. 2012 Feb; 61(2): 169–179. Published online 2011 Aug 27. doi: 10.1007/s00262-011-1095-2

PMCID:: PMC11028920

Abstract Article PDF–597K

Select item 66886622.

Crystal structure of the inhibitor-free form of the serine protease kallikrein-4

Blake T. Riley, David E. Hoke, Sheena McGowan, Ashley M. Buckle

Acta Crystallogr F Struct Biol Commun. 2019 Aug 1; 75(Pt 8): 543–546. Published online 2019 Jul 16. doi: 10.1107/S2053230X19009610

PMCID:: PMC6688662

Abstract Article PDF–575K

Select item 63922723.

Characterization of kallikrein-related peptidase 4 (KLK4) mRNA expression in tumor tissue of advanced high-grade serous ovarian cancer patients

Weiwei Gong, Yueyang Liu, Christof Seidl, Tobias Dreyer, Enken Drecoll, Matthias Kotzsch, Holger Bronger, Julia Dorn, Viktor Magdolen

PLoS One. 2019; 14(2): e0212968. Published online 2019 Feb 27. doi: 10.1371/journal.pone.0212968

PMCID:: PMC6392272

Abstract Article PDF–991K

Select item 56238154.

Thomas Kryza, Lakmali M. Silva, Nathalie Bock, Ruth A. Fuhrman‐Luck, Carson R. Stephens, Jin Gao, Hema Samaratunga, Australian Prostate Cancer BioResource, Mitchell G. Lawrence, John D. Hooper, Ying Dong, Gail P. Risbridger, Judith A. Clements

Mol Oncol. 2017 Oct; 11(10): 1307–1329. Published online 2017 Aug 10. doi: 10.1002/1878-0261.12075

PMCID:: PMC5623815

Abstract Article PDF–1.2M

Select item 50733545.

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics

Blake T. Riley, Olga Ilyichova, Mauricio G. S. Costa, Benjamin T. Porebski, Simon J. de Veer, Joakim E. Swedberg, Itamar Kass, Jonathan M. Harris, David E. Hoke, Ashley M. Buckle

Sci Rep. 2016; 6: 35385. Published online 2016 Oct 21. doi: 10.1038/srep35385

PMCID:: PMC5073354

Abstract Article PDF–2.5M

Select item 45772326.

Clinical Significance of Kallikrein-related-peptidase-4 in Oral Cancer

PETROS PAPAGERAKIS, GIUSEPPE PANNONE, LI ZHENG, MARIA ATHANASSIOU-PAPAEFTHYMIOU, YASHUO YAMAKOSHI, HOWARD STAN McGUFF, OMAR SHKEIR, KONSTANTINOS GHIRTIS, SILVANA PAPAGERAKIS

Anticancer Res. Author manuscript; available in PMC 2015 Sep 21.

Published in final edited form as: Anticancer Res. 2015 Apr; 35(4): 1861–1866.

PMCID:: PMC4577232

Abstract Article PDF–786K

Select item 34352907.

Genetic Association of the KLK4 Locus with Risk of Prostate Cancer

Felicity Lose, Srilakshmi Srinivasan, Tracy O’Mara, Louise Marquart, Suzanne Chambers, Robert A. Gardiner, Joanne F. Aitken, the Australian Prostate Cancer BioResource, Amanda B. Spurdle, Jyotsna Batra, Judith A. Clements

PLoS One. 2012; 7(9): e44520. Published online 2012 Sep 6. doi: 10.1371/journal.pone.0044520

PMCID:: PMC3435290

Abstract Article PDF–204K

Select item 28741688.

A variant of the KLK4 gene is expressed as a cis sense–antisense chimeric transcript in prostate cancer cells

John Lai, Melanie L. Lehman, Marcel E. Dinger, Stephen C. Hendy, Tim R. Mercer, Inge Seim, Mitchell G. Lawrence, John S. Mattick, Judith A. Clements, Colleen C. Nelson

RNA. 2010 Jun; 16(6): 1156–1166. doi: 10.1261/rna.2019810

PMCID:: PMC2874168

Abstract Article PDF–866K

Select item 66860159.

A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases

Daisuke Nishimiya, Yoshirou Kawaguchi, Shiho Kodama, Hatsumi Nasu, Hidenori Yano, Aya Yamaguchi, Masakazu Tamura, Ryuji Hashimoto

Sci Rep. 2019; 9: 11436. Published online 2019 Aug 7. doi: 10.1038/s41598-019-47615-5

PMCID:: PMC6686015

Abstract Article PDF–1.3M

Select item 633328210.

Crystal structures of the complex of a kallikrein inhibitor from Bauhinia bauhinioides with trypsin and modeling of kallikrein complexes

Mi Li, Jaroslav Srp, Alla Gustchina, Zbigniew Dauter, Michael Mares, Alexander Wlodawer

Acta Crystallogr D Struct Biol. 2019 Jan 1; 75(Pt 1): 56–69. Published online 2019 Jan 7. doi: 10.1107/S2059798318016492

PMCID:: PMC6333282

Abstract Article PDF–3.3M

Select item 606462411.

Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression

Dongmei Zhang, Jingrong Lin, Yulin Chao, Lu Zhang, Lei Jin, Na Li, Ruiping He, Binbin Ma, Wenzhi Zhao, Chuanchun Han

J Exp Clin Cancer Res. 2018; 37: 176. Published online 2018 Jul 28. doi: 10.1186/s13046-018-0842-z

Correction in:: J Exp Clin Cancer Res. 2021; 40: 385.

PMCID:: PMC6064624

Abstract Article PDF–5.7M

Select item 283216412.

Valérie Gratio, Nathalie Beaufort, Lina Seiz, Josefine Maier, G. Duke Virca, Mekdes Debela, Nicolai Grebenchtchikov, Viktor Magdolen, Dalila Darmoul

Am J Pathol. 2010 Mar; 176(3): 1452–1461. doi: 10.2353/ajpath.2010.090523

PMCID:: PMC2832164

Abstract Article PDF–884K

Select item 173584713.

Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta

P Hart, T Hart, M Michalec, O Ryu, D Simmons, S Hong, J Wright

J Med Genet. 2004 Jul; 41(7): 545–549. doi: 10.1136/jmg.2003.017657

PMCID:: PMC1735847

Summary PDF–1.1M

Select item 1590414.

Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression

Peter S. Nelson, Lu Gan, Camari Ferguson, Patrick Moss, Richard Gelinas, Leroy Hood, Kai Wang

Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6): 3114–3119. doi: 10.1073/pnas.96.6.3114

PMCID:: PMC15904

Abstract Article PDF–239K

Select item 357699815.

Novel KLK4 and MMP20 Mutations Discovered by Whole-exome Sequencing

S.-K. Wang, Y. Hu, J.P. Simmer, F. Seymen, N.M.R.P. Estrella, S. Pal, B.M. Reid, M. Yildirim, M. Bayram, J.D. Bartlett, J.C.-C. Hu

J Dent Res. 2013 Mar; 92(3): 266–271. doi: 10.1177/0022034513475626

PMCID:: PMC3576998

Abstract Article PDF–496K

Select item 487583716.

Maturation Stage Enamel Malformations in Amtn and Klk4 Null Mice

Stephanie M. Nunez, Yong-Hee P. Chun, Bernhard Ganss, Yuanyuan Hu, Amelia S Richardson, James E. Schmitz, Roberto Fajardo, Jie Yang, Jan C-C. Hu, James P. Simmer

Matrix Biol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Matrix Biol. 2016 May-Jul; 52-54: 219–233. Published online 2015 Nov 24. doi: 10.1016/j.matbio.2015.11.007

PMCID:: PMC4875837

Abstract Article PDF–5.3M

Select item 371088517.

Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer

Yang Jin, Su Qu, Martina Tesikova, Ling Wang, Alexandr Kristian, Gunhild M. Mælandsmo, Haiying Kong, Tianzhou Zhang, Carmen Jerónimo, Manuel R. Teixeira, Erkan Yuca, Ibrahim Tekedereli, Kivanc Gorgulu, Neslihan Alpay, Anil K. Sood, Gabriel Lopez-Berestein, Håvard E. Danielsen, Bulent Ozpolat, Fahri Saatcioglu

Proc Natl Acad Sci U S A. 2013 Jul 9; 110(28): E2572–E2581. Published online 2013 Jun 24. doi: 10.1073/pnas.1304318110

PMCID:: PMC3710885

Abstract Article PDF–1.3M

Select item 331804418.

MMP20 Hemopexin Domain Mutation in Amelogenesis Imperfecta

S.-K. Lee, F. Seymen, H.-Y. Kang, K.-E. Lee, K. Gencay, B. Tuna, J.-W. Kim

J Dent Res. 2010 Jan; 89(1): 46–50. doi: 10.1177/0022034509352844

PMCID:: PMC3318044

Abstract Article PDF–422K

Select item 275486319.

Human and Mouse Enamel Phenotypes Resulting from Mutation or Altered Expression of AMEL, ENAM, MMP20 and KLK4

J. Timothy Wright, Thomas C. Hart, P. Suzanne Hart, Darrin Simmons, Cynthia Suggs, Bill Daley, Jim Simmer, Jan Hu, John D. Bartlett, Yong Li, Zhi-An Yuan, W. Kim Seow, Carolyn W. Gibson

Cells Tissues Organs. 2008 Dec; 189(1-4): 224–229. Published online 2008 Aug 19. doi: 10.1159/000151378

PMCID:: PMC2754863

Abstract Article PDF–562K

Select item 373200920.

Susceptibility Loci Associated with Prostate Cancer Progression and Mortality

David J. Gallagher, Joseph Vijai, Angel M. Cronin, Jasmine Bhatia, Andrew J. Vickers, Mia M. Gaudet, Samson Fine, Victor Reuter, Howard I. Scher, Christer Halldén, Ana Dutra-Clarke, Robert J. Klein, Peter T. Scardino, James A. Eastham, Hans Lilja, Tomas Kirchhoff, Kenneth Offit

Clin Cancer Res. Author manuscript; available in PMC 2013 Aug 2.

Published in final edited form as: Clin Cancer Res. 2010 May 15; 16(10): 2819–2832. Published online 2010 May 11. doi: 10.1158/1078-0432.CCR-10-0028

PMCID:: PMC3732009

Abstract Article PDF–683K

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