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Items: 1 to 20 of 104

1.
CTR9 drives osteochondral lineage differentiation of human mesenchymal stem cells via epigenetic regulation of BMP-2 signaling
Ngai Ting Chan, Ming-Song Lee, Yidan Wang, Jacques Galipeau, Wan-Ju Li, Wei Xu
Sci Adv. 2022 Nov; 8(46): eadc9222. Published online 2022 Nov 16. doi: 10.1126/sciadv.adc9222
PMCID:
PMC9668309
AbstractArticlePDF–3.2M
2.
The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium
Ngai Ting Chan, Junfeng Huang, Gui Ma, Hao Zeng, Kristine Donahue, Yidan Wang, Lingjun Li, Wei Xu
Nucleic Acids Res. 2022 Feb 28; 50(4): 1969–1992. Published online 2022 Feb 7. doi: 10.1093/nar/gkac047
PMCID:
PMC8887485
AbstractArticlePDF–8.4M
3.
CTR9‐mediated JAK2/STAT3 pathway promotes the proliferation, migration, and invasion of human glioma cells
Yang Xu, Jiaguo Chen, Gao He, Yuhai Zhang
J Clin Lab Anal. 2021 Sep; 35(9): e23943. Published online 2021 Aug 8. doi: 10.1002/jcla.23943
PMCID:
PMC8418497
AbstractArticlePDF–2.0M
4.
Systematic identification of Ctr9 regulome in ERα-positive breast cancer
Hao Zeng, Li Lu, Ngai Ting Chan, Mark Horswill, Paul Ahlquist, Xuehua Zhong, Wei Xu
BMC Genomics. 2016; 17: 902. Published online 2016 Nov 9. doi: 10.1186/s12864-016-3248-3
PMCID:
PMC5103509
AbstractArticlePDF–2.5M
5.
Ctr9, a key subunit of PAFc, affects global estrogen signaling and drives ERα-positive breast tumorigenesis
Hao Zeng, Wei Xu
Genes Dev. 2015 Oct 15; 29(20): 2153–2167. doi: 10.1101/gad.268722.115
PMCID:
PMC4617979
AbstractArticlePDF–1.9M
6.
Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour
Sandra Hanks, Elizabeth R. Perdeaux, Sheila Seal, Elise Ruark, Shazia S. Mahamdallie, Anne Murray, Emma Ramsay, Silvana Del Vecchio Duarte, Anna Zachariou, Bianca de Souza, Margaret Warren-Perry, Anna Elliott, Alan Davidson, Helen Price, Charles Stiller, Kathy Pritchard-Jones, Nazneen Rahman
Nat Commun. 2014 Aug 7; 5: 4398. Published online 2014 Aug 7. doi: 10.1038/ncomms5398
PMCID:
PMC4143912
AbstractArticlePDF–495K
7.
CTR9, a Component of PAF Complex, Controls Elongation Block at the c-Fos Locus via Signal-Dependent Regulation of Chromatin-Bound NELF Dissociation
Hyun-Seok Yoo, Jung-Hwa Seo, Joo-Yeon Yoo
PLoS One. 2013; 8(4): e61055. Published online 2013 Apr 11. doi: 10.1371/journal.pone.0061055
PMCID:
PMC3623864
AbstractArticlePDF–1.0M
8.
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity
Bin Zhang, Zhi-yi Liu, Rui Wu, Cheng-ming Zhang, Kuan Cao, Wen-gang Shan, Zhen Liu, Ming Ji, Zi-lu Tian, Gautam Sethi, Heng-liang Shi, Ren-hao Wang
Acta Pharmacol Sin. 2022 Aug; 43(8): 2109–2118. Published online 2021 Dec 7. doi: 10.1038/s41401-021-00812-3
PMCID:
PMC9343652
AbstractArticlePDF–2.9M
9.
MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9
Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen
Eur J Histochem. 2022 Jan 12; 66(1): 3275. Published online 2022 Jan 12. doi: 10.4081/ejh.2022.3275
PMCID:
PMC8764465
AbstractArticlePDF–820K
10.
Depletion of Trypanosome CTR9 Leads to Gene Expression Defects
Benard A. Ouna, Benson Nyambega, Theresa Manful, Claudia Helbig, Matilda Males, Abeer Fadda, Christine Clayton
PLoS One. 2012; 7(4): e34256. Published online 2012 Apr 20. doi: 10.1371/journal.pone.0034256
PMCID:
PMC3332058
AbstractArticlePDF–432K
11.
Ctr9, a Protein in the Transcription Complex Paf1, Regulates Dopamine Transporter Activity at the Plasma Membrane
Stéphanie De Gois, Patrick Slama, Nicolas Pietrancosta, Amaia M. Erdozain, Franck Louis, Caroline Bouvrais-Veret, Laurent Daviet, Bruno Giros
J Biol Chem. 2015 Jul 17; 290(29): 17848–17862. Published online 2015 Jun 5. doi: 10.1074/jbc.M115.646315
PMCID:
PMC4505035
AbstractArticlePDF–2.8M
12.
Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome
Hwa-Young Sun, Nari Kim, Cheol-Sang Hwang, Joo-Yeon Yoo
PLoS One. 2015; 10(5): e0125599. Published online 2015 May 1. doi: 10.1371/journal.pone.0125599
PMCID:
PMC4416890
AbstractArticlePDF–4.4M
13.
saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription
Victoria Portnoy, Szu Hua Sharon Lin, Kathy H Li, Alma Burlingame, Zheng-Hui Hu, Hao Li, Long-Cheng Li
Cell Res. 2016 Mar; 26(3): 320–335. Published online 2016 Feb 23. doi: 10.1038/cr.2016.22
PMCID:
PMC4783471
AbstractArticlePDF–4.8M
14.
Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation
Ying Xie, Minying Zheng, Xinlei Chu, Yue Chen, Huisha Xu, Jiawei Wang, Hao Zhou, Jiafu Long
Nat Commun. 2018; 9: 3795. Published online 2018 Sep 18. doi: 10.1038/s41467-018-06237-7
PMCID:
PMC6143631
AbstractArticlePDF–2.0M
15.
PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia
James Ropa, Nirmalya Saha, Zhiling Chen, Justin Serio, Wei Chen, Dattatreya Mellacheruvu, Lili Zhao, Venkatesha Basrur, Alexey I. Nesvizhskii, Andrew G. Muntean
Oncotarget. 2018 Apr 24; 9(31): 22123–22136. Published online 2018 Apr 24. doi: 10.18632/oncotarget.25204
PMCID:
PMC5955148
AbstractArticlePDF–4.4M
16.
New and novel intrinsic host repressive factors against HIV-1: PAF1 complex, HERC5 and others
Mudit Tyagi, Fatah Kashanchi
Retrovirology. 2012; 9: 19. Published online 2012 Mar 9. doi: 10.1186/1742-4690-9-19
PMCID:
PMC3311033
ArticlePDF–214K
17.
The Parafibromin Tumor Suppressor Protein Is Part of a Human Paf1 Complex
Orit Rozenblatt-Rosen, Christina M. Hughes, Suraj J. Nannepaga, Kalai Selvi Shanmugam, Terry D. Copeland, Tad Guszczynski, James H. Resau, Matthew Meyerson
Mol Cell Biol. 2005 Jan; 25(2): 612–620. doi: 10.1128/MCB.25.2.612-620.2005
PMCID:
PMC543415
AbstractArticlePDF–443K
18.
Histone H3R17me2a mark recruits human RNA Polymerase-Associated Factor 1 Complex to activate transcription
Jiacai Wu, Wei Xu
Proc Natl Acad Sci U S A. 2012 Apr 10; 109(15): 5675–5680. Published online 2012 Mar 26. doi: 10.1073/pnas.1114905109
PMCID:
PMC3326481
AbstractArticlePDF–632K
19.
SHP2 Tyrosine Phosphatase Converts Parafibromin/Cdc73 from a Tumor Suppressor to an Oncogenic Driver
Atsushi Takahashi, Ryouhei Tsutsumi, Ippei Kikuchi, Chikashi Obuse, Yasuhiro Saito, Azadeh Seidi, Robert Karisch, Minerva Fernandez, Taewoo Cho, Naomi Ohnishi, Orit Rozenblatt-Rosen, Matthew Meyerson, Benjamin G. Neel, Masanori Hatakeyama
Mol Cell. Author manuscript; available in PMC 2016 Nov 9.
Published in final edited form as: Mol Cell. 2011 Jul 8; 43(1): 45–56. doi: 10.1016/j.molcel.2011.05.014
PMCID:
PMC5101830
AbstractArticlePDF–1.3M
20.
The HRPT2 Tumor Suppressor Gene Product Parafibromin Associates with Human PAF1 and RNA Polymerase II
Armelle Yart, Matthias Gstaiger, Christiane Wirbelauer, Maria Pecnik, Dimitrios Anastasiou, Daniel Hess, Wilhelm Krek
Mol Cell Biol. 2005 Jun; 25(12): 5052–5060. doi: 10.1128/MCB.25.12.5052-5060.2005
PMCID:
PMC1140601
AbstractArticlePDF–522K

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