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Select item 102906351.

PDE4DIP contributes to colorectal cancer growth and chemoresistance through modulation of the NF1/RAS signaling axis

Rulu Pan, Juji Dai, Weicheng Liang, Hongxiao Wang, Lin Ye, Siqi Ye, Ziqi Lin, Shishun Huang, Yan Xiong, Li Zhang, Liting Lu, Ouchen Wang, Xian Shen, Wanqin Liao, Xincheng Lu

Cell Death Dis. 2023 Jun; 14(6): 373. Published online 2023 Jun 24. doi: 10.1038/s41419-023-05885-y

PMCID:: PMC10290635

Abstract Article PDF–4.9M

Select item 73134742.

Bioinformatic Analysis Reveals Phosphodiesterase 4D-Interacting Protein as a Key Frontal Cortex Dementia Switch Gene

Judith A. Potashkin, Virginie Bottero, Jose A. Santiago, James P. Quinn

Int J Mol Sci. 2020 Jun; 21(11): 3787. Published online 2020 May 27. doi: 10.3390/ijms21113787

PMCID:: PMC7313474

Abstract Article PDF–3.5M

Select item 86847123.

Myomegalin regulates Hedgehog pathway by controlling PDE4D at the centrosome

Hualing Peng, Jingyi Zhang, Amanda Ya, Winston Ma, Sammy Villa, Shahar Sukenik, Xuecai Ge

Mol Biol Cell. 2021 Sep 1; 32(19): 1807–1817. doi: 10.1091/mbc.E21-02-0064

PMCID:: PMC8684712

Abstract Article PDF–1.5M

Select item 84349674.

Epistatic interaction of PDE4DIP and DES mutations in familial atrial fibrillation with slow conduction

Maen D. Abou Ziki, Neha Bhat, Arpita Neogi, Tristan P. Driscoll, Nelson Ugwu, Ya Liu, Emily Smith, Johny M Abboud, Salah Chouairi, Martin A. Schwartz, Joseph G. Akar, Arya Mani

Hum Mutat. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Hum Mutat. 2021 Oct; 42(10): 1279–1293. Published online 2021 Jul 29. doi: 10.1002/humu.24265

PMCID:: PMC8434967

Abstract Article PDF–1.1M

Select item 60546845.

Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma

Matija Snuderl, Kasthuri Kannan, Elke Pfaff, Shiyang Wang, James M. Stafford, Jonathan Serrano, Adriana Heguy, Karina Ray, Arline Faustin, Olga Aminova, Igor Dolgalev, Stacie L. Stapleton, David Zagzag, Luis Chiriboga, Sharon L. Gardner, Jeffrey H. Wisoff, John G. Golfinos, David Capper, Volker Hovestadt, Marc K. Rosenblum, Dimitris G. Placantonakis, Sarah E. LeBoeuf, Thales Y. Papagiannakopoulos, Lukas Chavez, Sama Ahsan, Charles G. Eberhart, Stefan M. Pfister, David T. W. Jones, Matthias A. Karajannis

Nat Commun. 2018; 9: 2868. Published online 2018 Jul 20. doi: 10.1038/s41467-018-05029-3

PMCID:: PMC6054684

Abstract Article PDF–2.5M

Select item 46739866.

Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project

Paul L. Auer, Mike Nalls, James F. Meschia, Bradford B. Worrall, W. T. Longstreth, Jr, Sudha Seshadri, Charles Kooperberg, Kathleen M. Burger, Christopher S. Carlson, Cara L. Carty, Wei-Min Chen, L. Adrienne Cupples, Anita L. DeStefano, Myriam Fornage, John Hardy, Li Hsu, Rebecca D. Jackson, Gail P. Jarvik, Daniel S. Kim, Kamakshi Lakshminarayan, Leslie A. Lange, Ani Manichaikul, Aaron R. Quinlan, Andrew B. Singleton, Timothy A. Thornton, Deborah A. Nickerson, Ulrike Peters, Stephen S. Rich, The National Heart Lung, and Blood Institute Exome Sequencing Project

JAMA Neurol. Author manuscript; available in PMC 2015 Dec 9.

Published in final edited form as: JAMA Neurol. 2015 Jul; 72(7): 781–788. doi: 10.1001/jamaneurol.2015.0582

PMCID:: PMC4673986

Abstract Article PDF–390K

Select item 34138927.

Identification of Novel Germline Polymorphisms Governing Capecitabine Sensitivity

Peter H. O’Donnell, Amy L. Stark, Eric R. Gamazon, Heather E. Wheeler, Bridget E. McIlwee, Lidija Gorsic, Hae Kyung Im, R. Stephanie Huang, Nancy J. Cox, M. Eileen Dolan

Cancer. Author manuscript; available in PMC 2013 Aug 15.

Published in final edited form as: Cancer. 2012 Aug 15; 118(16): 4063–4073. Published online 2012 Jan 3. doi: 10.1002/cncr.26737

PMCID:: PMC3413892

Abstract Article PDF–1.7M

Select item 21691798.

Protein Kinase A, Ca²⁺/Calmodulin-Dependent Kinase II, and Calcineurin Regulate the Intracellular Trafficking of Myopodin between the Z-Disc and the Nucleus of Cardiac Myocytes

Christian Faul, Ashwini Dhume, Alison D. Schecter, Peter Mundel

Mol Cell Biol. 2007 Dec; 27(23): 8215–8227. Published online 2007 Oct 8. doi: 10.1128/MCB.00950-07

PMCID:: PMC2169179

Abstract Article PDF–1.3M

Select item 31034379.

Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C

Gerrida M Uys, Amsha Ramburan, Benjamin Loos, Craig J Kinnear, Lundi J Korkie, Jomien Mouton, Johann Riedemann, Johanna C Moolman-Smook

BMC Cell Biol. 2011; 12: 18. Published online 2011 May 10. doi: 10.1186/1471-2121-12-18

PMCID:: PMC3103437

Abstract Article PDF–1.8M

Select item 339041310.

Proteomic Profiling of the TRAF3 Interactome Network Reveals a New Role for the ER-to-Golgi Transport Compartments in Innate Immunity

Wendy J. van Zuylen, Priscilla Doyon, Jean-François Clément, Kashif Aziz Khan, Lisa M. D'Ambrosio, Florence Dô, Myriam St-Amant-Verret, Tasheen Wissanji, Gregory Emery, Anne-Claude Gingras, Sylvain Meloche, Marc J. Servant

PLoS Pathog. 2012 Jul; 8(7): e1002747. Published online 2012 Jul 5. doi: 10.1371/journal.ppat.1002747

PMCID:: PMC3390413

Abstract Article PDF–1.8M

Select item 405428911.

PEA15 Regulates the DNA Damage-Induced Cell Cycle Checkpoint and Oncogene-Directed Transformation

Arvindhan Nagarajan, Shaillay Kumar Dogra, Alex Y. Liu, Michael R. Green, Narendra Wajapeyee

Mol Cell Biol. 2014 Jun; 34(12): 2264–2282. doi: 10.1128/MCB.01542-13

PMCID:: PMC4054289

Abstract Article PDF–6.2M

Select item 255592312.

Arf GTPase-activating Protein ASAP1 Interacts with Rab11 Effector FIP3 and Regulates Pericentrosomal Localization of Transferrin Receptor–positive Recycling Endosome

Hiroki Inoue, Vi Luan Ha, Rytis Prekeris, Paul A. Randazzo

Mol Biol Cell. 2008 Oct; 19(10): 4224–4237. doi: 10.1091/mbc.E08-03-0290

PMCID:: PMC2555923

Abstract Article PDF–1.7M

Select item 574065513.

EB1-binding–myomegalin protein complex promotes centrosomal microtubules functions

Habib Bouguenina, Danièle Salaun, Aurélie Mangon, Leslie Muller, Emilie Baudelet, Luc Camoin, Taro Tachibana, Sarah Cianférani, Stéphane Audebert, Pascal Verdier-Pinard, Ali Badache

Proc Natl Acad Sci U S A. 2017 Dec 12; 114(50): E10687–E10696. Published online 2017 Nov 21. doi: 10.1073/pnas.1705682114

PMCID:: PMC5740655

Abstract Article PDF–2.4M

Select item 631391214.

Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A

Anna M. Schmoker, Samuel A. Barritt, Marion E. Weir, Jacqueline E. Mann, Tyler C. Hogan, Bryan A. Ballif, Paula B. Deming

Proteomes. 2018 Dec; 6(4): 37. Published online 2018 Sep 29. doi: 10.3390/proteomes6040037

PMCID:: PMC6313912

Abstract Article PDF–4.8M

Select item 669413215.

HENA, heterogeneous network-based data set for Alzheimer’s disease

Elena Sügis, Jerome Dauvillier, Anna Leontjeva, Priit Adler, Valerie Hindie, Thomas Moncion, Vincent Collura, Rachel Daudin, Yann Loe-Mie, Yann Herault, Jean-Charles Lambert, Henning Hermjakob, Tal Pupko, Jean-Christophe Rain, Ioannis Xenarios, Jaak Vilo, Michel Simonneau, Hedi Peterson

Sci Data. 2019; 6: 151. Published online 2019 Aug 14. doi: 10.1038/s41597-019-0152-0

PMCID:: PMC6694132

Abstract Article PDF–2.8M

Select item 333877516.

Intersectin (ITSN) Family of Scaffolds Function as Molecular Hubs in Protein Interaction Networks

Katy A. Wong, Jessica Wilson, Angela Russo, Li Wang, Mustafa Nazir Okur, Xuerong Wang, Negin P. Martin, Erica Scappini, Graeme K. Carnegie, John P. O'Bryan

PLoS One. 2012; 7(4): e36023. Published online 2012 Apr 27. doi: 10.1371/journal.pone.0036023

PMCID:: PMC3338775

Abstract Article PDF–1.7M

Select item 830719417.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 625176118.

Endogenous Cell Type-Specific DISC1 Interactomes Reveal Protein Networks Associated to Neurodevelopmental Disorders

Brent Wilkinson, Oleg Evgrafov, DongQing Zheng, Nicolas Hartel, James A. Knowles, Nicholas A. Graham, Justin Ichida, Marcelo P. Coba

Biol Psychiatry. Author manuscript; available in PMC 2020 Feb 15.

Published in final edited form as: Biol Psychiatry. 2019 Feb 15; 85(4): 305–316. Published online 2018 May 23. doi: 10.1016/j.biopsych.2018.05.009

PMCID:: PMC6251761

Abstract Article PDF–1.6M

Select item 794845219.

A conserved acetylation switch enables pharmacological control of tubby-like protein stability

Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard

J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839

PMCID:: PMC7948452

Abstract Article PDF–3.6M

Select item 1049982120.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

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