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Items: 1 to 20 of 35

1.
RAPGEF2 mediates oligomeric Aβ‐induced synaptic loss and cognitive dysfunction in the 3xTg‐AD mouse model of Alzheimer’s disease
You‐Na Jang, HoChung Jang, Gyu Hyun Kim, Jeong‐Eun Noh, Keun‐A Chang, Kea Joo Lee
Neuropathol Appl Neurobiol. 2021 Aug; 47(5): 625–639. Published online 2021 Jan 6. doi: 10.1111/nan.12686
PMCID:
PMC8359155
AbstractArticlePDF–1.9M
2.
Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex
Tao Ye, Jacque P. K. Ip, Amy K. Y. Fu, Nancy Y. Ip
Nat Commun. 2014 Sep 5; 5: 4826. Published online 2014 Sep 5. doi: 10.1038/ncomms5826
PMCID:
PMC4164783
AbstractArticlePDF–4.0M
3.
The PDZ Domain of the Guanine Nucleotide Exchange Factor PDZGEF Directs Binding to Phosphatidic Acid during Brush Border Formation
Sarah V. Consonni, Patricia M. Brouwer, Eleonora S. van Slobbe, Johannes L. Bos
PLoS One. 2014; 9(5): e98253. Published online 2014 May 23. doi: 10.1371/journal.pone.0098253
PMCID:
PMC4032295
AbstractArticlePDF–2.3M
4.
NEDD4-1 Regulates Migration and Invasion of Glioma Cells through CNrasGEF Ubiquitination In Vitro
Hao Zhang, Wenchen Nie, Xu Zhang, Gentang Zhang, Zhiqiang Li, Huaibing Wu, Qiong Shi, Yong Chen, Zhijun Ding, Xiuping Zhou, Rutong Yu
PLoS One. 2013; 8(12): e82789. Published online 2013 Dec 10. doi: 10.1371/journal.pone.0082789
PMCID:
PMC3858320
AbstractArticlePDF–3.1M
5.
Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2
Bingbing Zhu, Aili Cao, Jianhua Li, James Young, Jenny Wong, Shazia Ashraf, Agnieszka Bierzynska, Madhav C. Menon, Steven Hou, Charles Sawyers, Kirk N. Campbell, Moin A. Saleem, John C. He, Friedhelm Hildebrandt, Vivette D. D’Agati, Wen Peng, Lewis Kaufman
Kidney Int. Author manuscript; available in PMC 2020 May 29.
Published in final edited form as: Kidney Int. 2019 Sep; 96(3): 642–655. Published online 2019 Mar 28. doi: 10.1016/j.kint.2019.03.016
PMCID:
PMC7259463
AbstractArticlePDF–4.1M
6.
DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth
Hwajin Lee, Andrew E Jaffe, Jason I Feinberg, Rakel Tryggvadottir, Shannon Brown, Carolina Montano, Martin J Aryee, Rafael A Irizarry, Julie Herbstman, Frank R Witter, Lynn R Goldman, Andrew P Feinberg, M Daniele Fallin
Int J Epidemiol. 2012 Feb; 41(1): 188–199. Published online 2012 Mar 14. doi: 10.1093/ije/dyr237
PMCID:
PMC3304532
AbstractArticlePDF–1.0M
7.
The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG
Jennifer Aurandt, Haris G. Vikis, J. Silvio Gutkind, Natalie Ahn, Kun-Liang Guan
Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19): 12085–12090. Published online 2002 Aug 26. doi: 10.1073/pnas.142433199
PMCID:
PMC129402
AbstractArticlePDF–314K
8.
Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap.
M Spaargaren, J R Bischoff
Proc Natl Acad Sci U S A. 1994 Dec 20; 91(26): 12609–12613. doi: 10.1073/pnas.91.26.12609
Correction in:
Proc Natl Acad Sci U S A. 1995 Jul 3; 92(14): 6650.
PMCID:
PMC45488
SummaryPage BrowsePDF–1.5M
9.
Direct Binding of the β1 Adrenergic Receptor to the Cyclic AMP-Dependent Guanine Nucleotide Exchange Factor CNrasGEF Leads to Ras Activation
Youngshil Pak, Nam Pham, Daniela Rotin
Mol Cell Biol. 2002 Nov; 22(22): 7942–7952. doi: 10.1128/MCB.22.22.7942-7952.2002
PMCID:
PMC134719
AbstractArticlePDF–582K
10.
Rapgef2 Connects GPCR-Mediated cAMP Signals to ERK Activation in Neuronal and Endocrine Cells
Andrew C. Emery, Maribeth V. Eiden, Tomris Mustafa, Lee E. Eiden
Sci Signal. Author manuscript; available in PMC 2014 Feb 22.
Published in final edited form as: Sci Signal. 2013 Jun 25; 6(281): ra51. Published online 2013 Jun 25. doi: 10.1126/scisignal.2003993
PMCID:
PMC3932028
AbstractArticlePDF–2.6M
11.
Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth
Shu Hisata, Toshiaki Sakisaka, Takeshi Baba, Tomohiro Yamada, Kazuhiro Aoki, Michiyuki Matsuda, Yoshimi Takai
J Cell Biol. 2007 Aug 27; 178(5): 843–860. doi: 10.1083/jcb.200610073
PMCID:
PMC2064548
AbstractArticlePDF–4.4M
12.
JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function
Ana C. Monteiro, Ronen Sumagin, Carl R. Rankin, Giovanna Leoni, Michael J. Mina, Dirk M. Reiter, Thilo Stehle, Terence S. Dermody, Stacy A. Schaefer, Randy A. Hall, Asma Nusrat, Charles A. Parkos
Mol Biol Cell. 2013 Sep 15; 24(18): 2849–2860. doi: 10.1091/mbc.E13-06-0298
PMCID:
PMC3771947
AbstractArticlePDF–1.6M
13.
DNA Damage Regulates Translation through β-TRCP Targeting of CReP
Theresa B. Loveless, Benjamin R. Topacio, Ajay A. Vashisht, Shastyn Galaang, Katie M. Ulrich, Brian D. Young, James A. Wohlschlegel, David P. Toczyski
PLoS Genet. 2015 Jun; 11(6): e1005292. Published online 2015 Jun 19. doi: 10.1371/journal.pgen.1005292
PMCID:
PMC4474599
AbstractArticlePDF–12M
14.
Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase
Tai Young Kim, Priscila F. Siesser, Kent L. Rossman, Dennis Goldfarb, Kathryn Mackinnon, Feng Yan, XianHua Yi, Michael J. MacCoss, Randall T. Moon, Channing J. Der, Michael B. Major
Mol Cell Biol. 2015 Jan; 35(1): 167–181. Prepublished online 2014 Oct 20. Published online 2014 Dec 9. doi: 10.1128/MCB.00857-14
PMCID:
PMC4295375
AbstractArticlePDF–5.6M
15.
Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved
Tabish Hussain, Jaeho Lee, Martin C. Abba, Junjie Chen, C. Marcelo Aldaz
Front Oncol. 2018; 8: 591. Published online 2018 Dec 13. doi: 10.3389/fonc.2018.00591
PMCID:
PMC6300487
AbstractArticlePDF–1.8M
16.
Characterizing WW Domain Interactions of Tumor Suppressor WWOX Reveals Its Association with Multiprotein Networks
Mohammad Abu-Odeh, Tomer Bar-Mag, Haiming Huang, TaeHyung Kim, Zaidoun Salah, Suhaib K. Abdeen, Marius Sudol, Dana Reichmann, Sachdev Sidhu, Philip M. Kim, Rami I. Aqeilan
J Biol Chem. 2014 Mar 28; 289(13): 8865–8880. Published online 2014 Feb 18. doi: 10.1074/jbc.M113.506790
PMCID:
PMC3979411
AbstractArticlePDF–3.0M
17.
Interaction proteome of human Hippo signaling: modular control of the co‐activator YAP1
Simon Hauri, Alexander Wepf, Audrey van Drogen, Markku Varjosalo, Nic Tapon, Ruedi Aebersold, Matthias Gstaiger
Mol Syst Biol. 2013; 9: 713. Published online 2013 Dec 20. doi: 10.1002/msb.201304750
PMCID:
PMC4019981
AbstractArticlePDF–915K
18.
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation
Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang
Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5
PMCID:
PMC8314547
AbstractArticlePDF–3.7M
19.
A Human MAP Kinase Interactome
Sourav Bandyopadhyay, Chih-yuan Chiang, Jyoti Srivastava, Merril Gersten, Suhaila White, Russell Bell, Cornelia Kurschner, Christopher H. Martin, Mike Smoot, Sudhir Sahasrabudhe, Diane L. Barber, Sumit K. Chanda, Trey Ideker
Nat Methods. Author manuscript; available in PMC 2011 Apr 1.
Published in final edited form as: Nat Methods. 2010 Oct; 7(10): 801–805. doi: 10.1038/nmeth.1506
PMCID:
PMC2967489
AbstractArticlePDF–1.2M
20.
Large-Scale Concatenation cDNA Sequencing
Wei Yu, Björn Andersson, Kim C. Worley, Donna M. Muzny, Yan Ding, Wen Liu, Jennifer Y. Ricafrente, Meredith A. Wentland, Greg Lennon, Richard A. Gibbs
Genome Res. 1997 Apr; 7(4): 353–358. doi: 10.1101/gr.7.4.353
PMCID:
PMC139146
AbstractArticlePDF–62K

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