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Select item 81432121.

ATG13 dynamics in nonselective autophagy and mitophagy: insights from live imaging studies and mathematical modeling

Piero Dalle Pezze, Eleftherios Karanasios, Varvara Kandia, Maria Manifava, Simon A. Walker, Nicolas Gambardella Le Novère, Nicholas T. Ktistakis

Autophagy. 2021; 17(5): 1131–1141. Published online 2020 Apr 22. doi: 10.1080/15548627.2020.1749401

PMCID:: PMC8143212

Abstract Article PDF–5.9M

Select item 67141702.

ATG13 restricts viral replication by induction of type I interferon

Jiang‐long Du, Peng Ma, Chen Wang, Yan Zeng, Yu‐jia Xue, Xue‐cai Yang, Xue‐mei Wan, Fan‐fan Chang, Tian‐yu Zhao, Xiao‐ye Jia, Hai‐zhen Wang, Jing Liu, Zhong‐ren Ma, Xin Cao, Kui‐zheng Cai

J Cell Mol Med. 2019 Sep; 23(9): 6508–6511. Published online 2019 Jul 3. doi: 10.1111/jcmm.14483

PMCID:: PMC6714170

Article PDF–459K

Select item 110623863.

Metamorphosis by ATG13 and ATG101 in human autophagy initiation

Anoshi Patel, Alex C. Faesen

Autophagy. 2024; 20(4): 968–969. Published online 2023 Jul 2. doi: 10.1080/15548627.2023.2230054

PMCID:: PMC11062386

Abstract Article PDF–325K

Select item 88821704.

Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas

Ling Gao, Qian Zhang, Shaoming Li, Jingjing Zheng, Wenhao Ren, Keqian Zhi

Cell Death Dis. 2022 Feb; 13(2): 192. Published online 2022 Feb 26. doi: 10.1038/s41419-021-04497-8

PMCID:: PMC8882170

Abstract Article PDF–4.1M

Select item 78369305.

The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy

Yasir Mohamud, Yuan Chao Xue, Huitao Liu, Chen Seng Ng, Amirhossein Bahreyni, Eric Jan, Honglin Luo

Biochem Biophys Res Commun. 2021 Feb 12; 540: 75–82. Published online 2021 Jan 8. doi: 10.1016/j.bbrc.2020.12.091

PMCID:: PMC7836930

Abstract Article PDF–1.9M

Select item 72826246.

ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle

Zhiyuan Li, Xiaofei Tian, Xinmiao Ji, Junjun Wang, Hanxiao Chen, Dongmei Wang, Xin Zhang

PLoS Biol. 2020 Jun; 18(6): e3000288. Published online 2020 Jun 9. doi: 10.1371/journal.pbio.3000288

PMCID:: PMC7282624

Abstract Article PDF–4.8M

Select item 70474147.

CircMUC16 promotes autophagy of epithelial ovarian cancer via interaction with ATG13 and miR-199a

Xiaoling Gan, Hongtao Zhu, Xingwei Jiang, Samuel C. Obiegbusi, Min Yong, Xingtao Long, Jianguo Hu

Mol Cancer. 2020; 19: 45. Published online 2020 Feb 28. doi: 10.1186/s12943-020-01163-z

PMCID:: PMC7047414

Abstract Article PDF–7.3M

Select item 58914218.

The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation

Jun Hwan Kim, Dongyeob Seo, Sun‐Jick Kim, Dong Wook Choi, Jin Seok Park, Jihoon Ha, Jungwon Choi, Ji‐Hyung Lee, Su Myung Jung, Kyoung‐Wan Seo, Eun‐Woo Lee, Youn Sook Lee, Heesun Cheong, Cheol Yong Choi, Seok Hee Park

EMBO Rep. 2018 Apr; 19(4): e44378. Published online 2018 Feb 27. doi: 10.15252/embr.201744378

PMCID:: PMC5891421

Abstract Article PDF–2.0M

Select item 46483299.

Chaperone-like protein p32 regulates ULK1 stability and autophagy

H Jiao, G-Q Su, W Dong, L Zhang, W Xie, L-m Yao, P Chen, Z-X Wang, Y-C Liou, H You

Cell Death Differ. 2015 Nov; 22(11): 1812–1823. Published online 2015 Apr 23. doi: 10.1038/cdd.2015.34

PMCID:: PMC4648329

Abstract Article PDF–4.7M

Select item 459828610.

Structure of the Human Atg13-Atg101 HORMA Heterodimer: An Interaction Hub within the ULK1 Complex

Shiqian Qi, Do Jin Kim, Goran Stjepanovic, James H. Hurley

Structure. Author manuscript; available in PMC 2016 Oct 6.

Published in final edited form as: Structure. 2015 Oct 6; 23(10): 1848–1857. Published online 2015 Aug 20. doi: 10.1016/j.str.2015.07.011

PMCID:: PMC4598286

Abstract Article PDF–2.3M

Select item 788329411.

Regulation of autophagosome biogenesis by OFD1‐mediated selective autophagy

Manuela Morleo, Simona Brillante, Umberto Formisano, Luigi Ferrante, Fabrizia Carbone, Daniela Iaconis, Alessandro Palma, Viviana Buonomo, Angela Serena Maione, Paolo Grumati, Carmine Settembre, Brunella Franco

EMBO J. 2021 Feb 15; 40(4): e105120. Published online 2020 Dec 28. doi: 10.15252/embj.2020105120

PMCID:: PMC7883294

Abstract Article PDF–2.5M

Select item 317211812.

Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death

W Gao, Z Shen, L Shang, X Wang

Cell Death Differ. 2011 Oct; 18(10): 1598–1607. Published online 2011 Apr 8. doi: 10.1038/cdd.2011.33

PMCID:: PMC3172118

Abstract Article PDF–633K

Select item 835460413.

LUBAC and OTULIN regulate autophagy initiation and maturation by mediating the linear ubiquitination and the stabilization of ATG13

Yuanyuan Chu, Yingjin Kang, Cong Yan, Cuiwei Yang, Tao Zhang, Huanhuan Huo, Yanfen Liu

Autophagy. 2021; 17(7): 1684–1699. Published online 2020 Jun 26. doi: 10.1080/15548627.2020.1781393

PMCID:: PMC8354604

Abstract Article PDF–10M

Select item 750568014.

Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

Luke M. Simpson, Thomas J. Macartney, Alice Nardin, Luke J. Fulcher, Sascha Röth, Andrea Testa, Chiara Maniaci, Alessio Ciulli, Ian G. Ganley, Gopal P. Sapkota

Cell Chem Biol. 2020 Sep 17; 27(9): 1164–1180.e5. doi: 10.1016/j.chembiol.2020.06.013

PMCID:: PMC7505680

Abstract Article

Select item 593225415.

Autophagic Flux is Regulated by Interaction Between the C-terminal Domain of Patched1 and ATG101

Lucy X. Chen, Cintli C. Morales-Alcala, Natalia A. Riobo-Del Galdo

Mol Cancer Res. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Mol Cancer Res. 2018 May; 16(5): 909–919. Published online 2018 Feb 16. doi: 10.1158/1541-7786.MCR-17-0597

PMCID:: PMC5932254

Abstract Article PDF–2.4M

Select item 574897116.

p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1

Yingli He, Hua She, Ting Zhang, Haidong Xu, Lihong Cheng, Manuel Yepes, Yingren Zhao, Zixu Mao

J Cell Biol. 2018 Jan 2; 217(1): 315–328. doi: 10.1083/jcb.201701049

PMCID:: PMC5748971

Abstract Article PDF–2.4M

Select item 698476217.

The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation

Byeong-Won Kim, Yunjung Jin, Jiyea Kim, Jun Hoe Kim, Juneyoung Jung, Seongman Kang, Ick Young Kim, Joungmok Kim, Heesun Cheong, Hyun Kyu Song

Autophagy. 2018; 14(12): 2104–2116. Published online 2018 Aug 16. doi: 10.1080/15548627.2018.1504716

PMCID:: PMC6984762

Abstract Article PDF–2.0M

Select item 647715218.

The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria

Benjamin J. Ravenhill, Keith B. Boyle, Natalia von Muhlinen, Cara J. Ellison, Glenn R. Masson, Elsje G. Otten, Agnes Foeglein, Roger Williams, Felix Randow

Mol Cell. 2019 Apr 18; 74(2): 320–329.e6. doi: 10.1016/j.molcel.2019.01.041

PMCID:: PMC6477152

Abstract Article

Select item 595932319.

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction

Ji-Man Park, Minchul Seo, Chang Hwa Jung, Douglas Grunwald, Matthew Stone, Neil Michael Otto, Erik Toso, Yeseul Ahn, Michael Kyba, Timothy J. Griffin, LeeAnn Higgins, Do-Hyung Kim

Autophagy. 2018; 14(4): 584–597. Published online 2018 Feb 21. doi: 10.1080/15548627.2017.1422851

PMCID:: PMC5959323

Abstract Article PDF–1.2M

Select item 532304620.

Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator

Jennifer Jung, Arnab Nayak, Véronique Schaeffer, Tatjana Starzetz, Achim K Kirsch, Stefan Müller, Ivan Dikic, Michel Mittelbronn, Christian Behrends

eLife. 2017; 6: e23063. Published online 2017 Feb 14. doi: 10.7554/eLife.23063

PMCID:: PMC5323046

Abstract Article PDF–5.8M

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PMC Links for Gene (Select 9776) (78)
PMC
Homo sapiens coiled-coil domain containing 3, mRNA (cDNA clone MGC:59716 IMAGE:6...
Homo sapiens coiled-coil domain containing 3, mRNA (cDNA clone MGC:59716 IMAGE:6302570), complete cds
gi|30410961|gb|BC051334.1|

Nucleotide
autophagy-related protein 13 isoform c [Homo sapiens]
autophagy-related protein 13 isoform c [Homo sapiens]
gi|1077193449|ref|NP_001333256.1|

Protein
Homo sapiens HT-1080 protein mRNA, complete cds
Homo sapiens HT-1080 protein mRNA, complete cds
gi|3551741|gb|U27112.1|

Nucleotide

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