PMC Links for Gene (Select 9874) - PMC

Fangfang Wu, Bing Han, Shusheng Wu, Li Yang, Shuo Leng, Mingyue Li, Jiefeng Liao, Guangtian Wang, Qingqing Ye, Yuan Zhang, Haifeng Chen, Xufeng Chen, Ming Zhong, Yun Xu, Qiang Liu, John H. Zhang, Honghong Yao

J Neurosci. 2019 Sep 11; 39(37): 7369–7393. doi: 10.1523/JNEUROSCI.0299-19.2019

PMCID:: PMC6759031

Abstract Article PDF–7.3M

Select item 52571994.

Tousled Kinase Activator, Gallic Acid, Promotes Homologous Recombinational Repair and Suppresses Radiation Cytotoxicity in Salivary Gland Cells

Prakash Srinivasan Timiri Shanmugam, Renjith Nair, Arrigo De Benedetti, Gloria Caldito, Fleurette Abreo, Gulshan Sunavala-Dossabhoy

Free Radic Biol Med. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: Free Radic Biol Med. 2016 Apr; 93: 217–226. Published online 2016 Feb 15. doi: 10.1016/j.freeradbiomed.2015.12.029

PMCID:: PMC5257199

Abstract Article PDF–2.1M

Select item 100359525.

The interaction between ASF1B and TLK1 promotes the malignant progression of low-grade glioma

Zifa Zhang, Shuming Liu

Ann Med. 2023; 55(1): 1111–1122. Published online 2023 Mar 22. doi: 10.1080/07853890.2023.2169751

PMCID:: PMC10035952

Abstract Article PDF–4.1M

Select item 92518786.

TLK1‐mediated MK5‐S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies

Md Imtiaz Khalil, Vibha Singh, Judy King, Arrigo De Benedetti

Mol Oncol. 2022 Jul; 16(13): 2537–2557. Published online 2022 Feb 3. doi: 10.1002/1878-0261.13183

PMCID:: PMC9251878

Abstract Article PDF–5.0M

Select item 74085027.

Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres

Sandra Segura-Bayona, Marina Villamor-Payà, Camille Stephan-Otto Attolini, Lars M. Koenig, Maria Sanchiz-Calvo, Simon J. Boulton, Travis H. Stracker

Cell Rep. 2020 Aug 4; 32(5): 107983. Published online 2020 Aug 4. doi: 10.1016/j.celrep.2020.107983

PMCID:: PMC7408502

Abstract Article

Select item 70281568.

The TLK1/Nek1 axis contributes to mitochondrial integrity and apoptosis prevention via phosphorylation of VDAC1

Vibha Singh, Md Imtiaz Khalil, Arrigo De Benedetti

Cell Cycle. 2020; 19(3): 363–375. Published online 2020 Jan 9. doi: 10.1080/15384101.2019.1711317

PMCID:: PMC7028156

Abstract Article PDF–4.5M

Select item 66177299.

Targeting the TLK1/NEK1 DDR axis with Thioridazine suppresses outgrowth of androgen independent prostate tumors

Vibha Singh, Praveen Kumar Jaiswal, Ishita Ghosh, Hari K. Koul, Xiuping Yu, Arrigo De Benedetti

Int J Cancer. 2019 Aug 15; 145(4): 1055–1067. Published online 2019 Feb 25. doi: 10.1002/ijc.32200

PMCID:: PMC6617729

Abstract Article PDF–53M

Select item 474692210.

TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint

Sanket Awate, Arrigo De Benedetti

BMC Mol Biol. 2016; 17: 3. Published online 2016 Feb 9. doi: 10.1186/s12867-016-0056-x

PMCID:: PMC4746922

Abstract Article PDF–5.1M

Select item 386994211.

Tousled-Like Kinase-Dependent Phosphorylation of Rad9 Plays a Role in Cell Cycle Progression and G2/M Checkpoint Exit

Ryan Kelly, Scott K. Davey

PLoS One. 2013; 8(12): e85859. Published online 2013 Dec 20. doi: 10.1371/journal.pone.0085859

PMCID:: PMC3869942

Abstract Article PDF–1.4M

Select item 124223112.

The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks

Gulshan Sunavala-Dossabhoy, Sri Kripa Balakrishnan, Siddhartha Sen, Sam Nuthalapaty, Arrigo De Benedetti

BMC Mol Biol. 2005; 6: 19. Published online 2005 Sep 12. doi: 10.1186/1471-2199-6-19

PMCID:: PMC1242231

Abstract Article PDF–886K

Select item 841919613.

CircTLK1 modulates sepsis‐induced cardiomyocyte apoptosis via enhancing PARP1/HMGB1 axis–mediated mitochondrial DNA damage by sponging miR‐17‐5p

Yu Qiu, Ying Yu, Xiao‐Mei Qin, Tao Jiang, Yan‐Fang Tan, Wen‐Xian Ouyang, Zheng‐Hui Xiao, Shuang‐Jie Li

J Cell Mol Med. 2021 Sep; 25(17): 8244–8260. Published online 2021 Aug 19. doi: 10.1111/jcmm.16738

PMCID:: PMC8419196

Abstract Article PDF–3.4M

Select item 622622614.

Loss of miR-16 contributes to tumor progression by activation of tousled-like kinase 1 in oral squamous cell carcinoma

Shousen Hu, Honghan Wang, Dan Yan, Wuhao Lu, Pei Gao, Weihua Lou, Xiangzhen Kong

Cell Cycle. 2018; 17(18): 2284–2295. Published online 2018 Oct 9. doi: 10.1080/15384101.2018.1526601

PMCID:: PMC6226226

Abstract Article PDF–1.4M

Select item 397704615.

Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication

Ilnaz M Klimovskaia, Clifford Young, Caroline B Strømme, Patrice Menard, Zuzana Jasencakova, Jakob Mejlvang, Katrine Ask, Michael Ploug, Michael L Nielsen, Ole N Jensen, Anja Groth

Nat Commun. Author manuscript; available in PMC 2014 Sep 6.

Published in final edited form as: Nat Commun. 2014; 5: 3394. Published online 2014 Mar 6. doi: 10.1038/ncomms4394

PMCID:: PMC3977046

Abstract Article PDF–3.3M

Select item 162647816.

TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1

Siddhartha P Sen, Arrigo De Benedetti

BMC Mol Biol. 2006; 7: 37. Published online 2006 Oct 20. doi: 10.1186/1471-2199-7-37

PMCID:: PMC1626478

Abstract Article PDF–2.2M

Select item 2574117.

Phosphorylation of SNAP-23 by the Novel Kinase SNAK Regulates t-SNARE Complex Assembly

J.-P. Cabaniols, V. Ravichandran, P.A. Roche

Mol Biol Cell. 1999 Dec; 10(12): 4033–4041. doi: 10.1091/mbc.10.12.4033

PMCID:: PMC25741

Abstract Article PDF–577K

Select item 546208518.

Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity

Vibha Singh, Zachary M. Connelly, Xinggui Shen, Arrigo De Benedetti

Cell Cycle. 2017; 16(10): 915–926. Published online 2017 Apr 20. doi: 10.1080/15384101.2017.1314421

PMCID:: PMC5462085

Abstract Article PDF–1.1M

Select item 1035569319.

CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis

Liting Kuang, Anshang Lu, Shaojuan Yao

Ren Fail. 2023; 45(1): 2236219. Published online 2023 Jul 18. doi: 10.1080/0886022X.2023.2236219

PMCID:: PMC10355693

Abstract Article PDF–1.7M

Select item 279144320.

Phosphorylation-Mediated Control of Histone Chaperone ASF1 Levels by Tousled-Like Kinases

Maxim Pilyugin, Jeroen Demmers, C. Peter Verrijzer, Francois Karch, Yuri M. Moshkin

PLoS One. 2009; 4(12): e8328. Published online 2009 Dec 16. doi: 10.1371/journal.pone.0008328

PMCID:: PMC2791443

Abstract Article PDF–398K

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PMC Links for Gene (Select 9874) (55)
PMC
PREDICTED: Homo sapiens tousled like kinase 1 (TLK1), transcript variant X2, mRN...
PREDICTED: Homo sapiens tousled like kinase 1 (TLK1), transcript variant X2, mRNA
gi|2462578970|ref|XM_054344769.1|

Nucleotide
PREDICTED: Homo sapiens flagellum associated containing coiled-coil domains 1 (F...
PREDICTED: Homo sapiens flagellum associated containing coiled-coil domains 1 (FLACC1), transcript variant X7, mRNA
gi|2217325606|ref|XM_047443396.1|

Nucleotide
flagellum-associated coiled-coil domain-containing protein 1 isoform X4 [Homo sa...
flagellum-associated coiled-coil domain-containing protein 1 isoform X4 [Homo sapiens]
gi|2462570119|ref|XP_054196513.1|

Protein
RecName: Full=Serine/threonine-protein kinase tousled-like 1; AltName: Full=PKU-...
RecName: Full=Serine/threonine-protein kinase tousled-like 1; AltName: Full=PKU-beta; AltName: Full=Tousled-like kinase 1
gi|34223086|sp|Q9UKI8.2|TLK1_HUMAN

Protein

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